Ferroptosis and recurrent miscarriage: a critical review of pathophysiology and emerging therapeutic targets by Mohammad Masoud Khodaei, Zahra Noori, Fateme Zare, Ahmad Meshkin

“…Further, new strategies targeting non-coding RNAs, and epigenetic regulators emphasize ferroptosis as a viable therapeutic target. …”
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LncRNA NRAD1 regulates the triple-negative breast cancer transcriptome by miRNA biogenesis, localization, and predominately non-ceRNA interactions by Hannah F. Cahill, Justin M. Brown, Manhattan Leslie-Toogood, Jaganathan Venkatesh, Marie-Claire D. Wasson, Raj Pranap Arun, Meghan E. McLean, Dejan Vidovic, Paola Marcato

“…These findings demonstrate novel regulatory interactions between the cancer-promoting lncRNA NRAD1 and miRNAs that alter gene expression in TNBC, expanding our understanding of regulatory lncRNA–miRNA effects, TNBC biology, and highlighting future therapeutic strategies for targeting non-coding RNAs.…”
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Osthole mitigates the myofibroblast properties in oral submucous fibrosis by suppressing the TGF-β/smad2 signaling pathway and NCK-AS1 expression by Po-Yu Yang, Pei-Ling Hsieh, Jung-Chun Yeh, Chun-Te Ho, Yi-Wen Liao, Yu-Lei Wei, Shih-Min Wang, Cheng-Chia Yu, Pei-Ming Chu

“…Background/purpose: Natural products are gaining increasing recognition as an alternative source for alleviating fibrosis as they can regulate various mediators or pathways against fibrosis by targeting non-coding RNAs. In the current study, we aimed to investigate the therapeutic effects of osthole in oral submucous fibrosis (OSF), a precancerous condition of the oral cavity. …”
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Systematic librarian-led zip code analysis to target underserved communities by Rachel Roberts, Kelsey L. Grabeel

“…Lastly, researchers also reviewed the hospital’s targeted zip codes to see if those overlapped with the top zip codes that utilize the health information service. …”
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Test data generation based on a formal analysis of the project conguration by A. V. Bataev, A. A. Davydov, N. Y. Nalutin, S. V. Sinitsyn

“…An approach the formalizing the target system code and requirements analysis is proposed. …”
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Nucleic acid therapeutics: Past, present, and future by Sajid Naeem, Ju Zhang, Yang Zhang, Yu Wang

“…Nucleic acid therapeutics have become increasingly recognized in recent years for their capability to target both coding and non-coding sequences. Several types of nucleic acid modalities, including siRNA, mRNA, aptamer, along with antisense oligo, have been approved by regulatory bodies for therapeutic use. …”
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Implementation of Polar Codes in 5G Systems with Different Waveform Modulations by Using USRP by Marwan Dhuheir, Sıtkı Öztürk

“…The OFDM signal istransmitted to the receiver at different frequencies which they are orthogonalto each other by dividing the bandwidth of a signal into smaller sub-carriers.Recently, the use of polar codes as a coding scheme in the new generation 5Gsystems has come to the communications markets. Polar codes as a channel codingscheme are a promising technique for the future because it is the first codesthat reach Shannon capacity limit. …”
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Comparing Social Media Platforms for Recruiting Special Education Teachers in a High-Need Area by Eric Landers, Caitlin Criss, Kathryn Haughney, Cynthia Massey, Stephanie Devine, Karin Fisher

“…Three groups were targeted (a) likely to have a bachelor’s degree, (b) likely to be associated with a targeted postal code, or (c) teacher candidates with a high likelihood of staying in a target area. …”
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Addressing Ethics in Plastic and Aesthetic Surgery: Società Italiana di Chirurgia Plastica Ricostruttiva ed Estetica’s Social Media Policy by Fabrizio Schonauer, MD, Anna Scarabosio, MD, Matilde Tettamanzi, MD, Monica Zena, MD, Annachiara Cavaliere, MD, Roberta Tornambene, MD, Mirco Pozzi, MD, Giulio Tarantino, MD, Daniele Matta, MD, Dorina Macchi, MD, Stefania De Fazio, MD

“…SICPRE’s ethical code, formulated through collaborative efforts and multiple revisions, includes 10 fundamental points addressing professionalism, transparency, patient privacy, and ethical marketing. The code was integrated into SICPRE’s broader ethical guidelines to ensure consistency and comprehensiveness. …”
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Acoustic Representation of Prosodic Cues during the Production of Persian Irony and Sarcasm in Spontaneous Discourse by Raha Koochacki, Mohammad Hossein Sharafzadeh, Ameneh Zare

“…Thereupon any pragmatic strategies (irony subtypes), the observed lexical-syntactic cues accompanied by the prosodic features of the target utterances coded considering TOBI system and using Praat software, were annotated manually in different ELAN tiers. …”
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Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals by Darine Villela, Rodrigo F. Ramalho, Aderbal R. T. Silva, Helena Brentani, Claudia K. Suemoto, Carlos Augusto Pasqualucci, Lea T. Grinberg, Ana C. V. Krepischi, Carla Rosenberg

“…This miRNA set is predicted to target 33 coding genes from the neuregulin receptor complex (ErbB) signaling pathway, which is required for the neurons myelination process. …”
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FingerDTA: A Fingerprint-Embedding Framework for Drug-Target Binding Affinity Prediction by Xuekai Zhu, Juan Liu, Jian Zhang, Zhihui Yang, Feng Yang, Xiaolei Zhang

“…Ultimately, the docking experiment demonstrates that FingerDTA can find novel drug candidates for targets. All codes are available at http://lanproxy.biodwhu.cn:9099/mszjaas/FingerDTA.git.…”
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MicroRNA-200b suppresses the invasion and migration of hepatocellular carcinoma by downregulating RhoA and circRNA_000839 by Ben-gang Wang, Jun-shuai Li, Yong-feng Liu, Qian Xu

“…MicroRNAs could mediate the targeted coding gene and the targeted non-coding RNA to form endogenous competition, which have an important regulatory role in tumorigenesis of many types of cancer, including hepatocellular carcinoma. …”
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GPCR-A17 MAAP: mapping modulators, agonists, and antagonists to predict the next bioactive target by Ana B. Caniceiro, Ana M. B. Amorim, Nícia Rosário-Ferreira, Irina S. Moreira

“…By guiding experimental validation, GPCR-A17 MAAP accelerates drug discovery for various therapeutic targets. The code and data are available on GitHub ( https://github.com/MoreiraLAB/GPCR-A17-MAAP ). …”
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Dysregulation of microRNA (miRNA) Due to Phthalate/Phthalate Metabolite Exposure and Associated Health Effects: A Narrative Review by Aamer Mohammed, Stephen L. Atkin, Edwina Brennan

“…As miRNAs mostly target protein-coding transcripts, they are involved in nearly all networks that regulate developmental and pathological processes. …”
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A protocol for microRNA extraction from gastrointestinal digesta by Miguel Cifuentes Acebal, Yvan Devaux, Torsten Bohn

“…MicroRNAs (miRNAs) are non-coding RNAs that influence gene-expression via post-transcriptional regulation of target protein-coding RNAs. With literature reports indicating survival of diet-derived miRNAs following their ingestion, it is important to study their stability and concentration during gastrointestinal digestion. …”
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Effective inhibition of dengue virus replication using 3′UTR-targeted Vivo-Morpholinos by Mengwei Niu, Wenyanbo Yi, Zhuofan Dong, Xiaofeng Li, Xue Dong, Lifang Yu, Yao Han, Oujia Zhang, Ziyang Sheng, Jing An, Hao Li, Yansong Sun

“…Nucleic acid drugs, particularly Vivo-Morpholinos (MOs), have emerged as a promising avenue for antiviral treatment due to their programmability and precise targeting, as well as their safety and stability.MethodIn this study, we designed and developed 10 morpho-modified (octa-guanidine dendrimer) vivo-MO molecules that target each coding gene of DENV. Subsequently, we assessed the inhibitory impact of vivo-MOs on dengue viral RNA load utilizing qRT-PCR. …”
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A quantitative PCR to detect non-toxigenic Clostridioides difficile by Khurshida Begum, Hubert C. Chua, M. Jahangir Alam, Kevin W. Garey, Jinhee Jo

“…To better guide clinical decisions and enhance the understanding of NTCD epidemiology, molecular assays that specifically target non-coding regions unique to NTCD strains are needed. …”
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Early Vascular Developmental Toxicity and Underlying Mechanisms of 1-Bromo-3,6-dichlorocarbazole (1-B-36-CCZ) in Zebrafish Larvae by Jie Gu, Ziyu Gong, Yue Fan, Jun Hu, Liguo Guo, Wenming Pei, Daqiang Yin

“…Enrichment analysis of target protein-coding genes and verapamil replication experiments indicated that 1-B-36-CCZ may cause damage to early vascular development in zebrafish larvae by altering intracellular calcium ion content through the activation of the SRC-mediated calcium ion signaling pathway. …”
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Identification and characterization of long non-coding RNA (lncRNA) in wild and semi-wild cucumbers by Shi-Wei Xia, Chang-Jiang Song, Xiao-Fang Zheng, Yuan Zhang, Wajid Anwar, Dissanayakalage D.N.V. Dissanayaka, Ping-Zhi Zhu, Jun-Li Liu, Yun-Song Lai

“…The competing endogenous RNA (ceRNA) network analysis revealed that 31 lncRNAs interacted with 26 miRNAs and competed for 134 targeted protein-coding genes. MiR156 plays a crucial role in the ceRNA network, competing with CsLncRNA94 to target the 7 members of the SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factor gene family. …”
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