The Impact of Baseline Risk Factors on the Incidence of Febrile Neutropenia in Breast Cancer Patients Receiving Chemotherapy with Pegfilgrastim Prophylaxis: A Real-World Data Analy... by Edward Li, Bridgette Kanz Schroader, David Campbell, Kim Campbell, Weijia Wang

“…Logistic regression and generalized estimating equations models were used to compare outcomes among patients with and without patient-specific risk factors and among those receiving regimens categorized as high-, intermediate-, or other-risk for FN (low-risk or undefinable by clinical practice guidelines). # Results A total of 4460 patients were identified. …”
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Combined Oral Contraceptives for Polycystic Ovary Syndrome: <i>Pro</i> and <i>Contra</i> (Review) by I. A. Mazerkina, I. G. Davydov, O. S. Alyautdina

“…Polycystic ovary syndrome (PCOS) is the main cause of female infertility. Clinical practice guidelines on PCOS recommend combined oral contraceptives (COCs) as first-line therapy. …”
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Rationale and Design of a Randomized Controlled Trial of Bivalirudin with a Prolonged High-Dose Infusion Versus Heparin Monotherapy During Primary Percutaneous Coronary Interventio... by Zhenyang Liang, Yi Li, Gregg W. Stone, Yaling Han

“…The procedures set out in this protocol are in accordance with the principles of the Declaration of Helsinki and Good Clinical Practice guidelines. The results will be published following the Consolidated Standards of Reporting Trials statement in a peer-reviewed scientific journal (Trial registration number: NCT03822975).…”
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The safety and efficacy of neutral electrolyzed water solution for wound irrigation: post-market clinical follow-up study by Veronika Valdová, Vladimíra Štěpánová, Lenka Lapčíková

“…A marked reduction in size was observed in all wound size categories. 19 (8%) patients healed by end of week 6; and 66 (28%) healed by week 9. 130 (55%) patients were considered healed by week 12.DiscussionThe current clinical practice guidelines refrain from recommending any of the available irrigation solutions and wound dressings due to low-quality evidence. …”
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Aerobic minutes and step number remain low in inpatient stroke rehabilitation. by Yunyi Yan, Janice J Eng, Stanley H Hung, Mark T Bayley, Krista L Best, Louise A Connell, Sarah J Donkers, Sean P Dukelow, Victor E Ezeugwu, Marie-Hélène Milot, Brodie M Sakakibara, Lisa Sheehy, Hubert Wong, Jennifer Yao, Sue Peters

“…<h4>Objective</h4>Rehabilitation is important for regaining mobility poststroke. Clinical practice guidelines suggest a high number of repetitive stepping activities to optimize subacute recovery especially when undertaken at intensities that challenge cardiovascular fitness. …”
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Cervical precancer thermal ablation versus LLETZ excision comparative efficacy study in WLWH (TALL Study): protocol for a randomised clinical trial in South Africa by Helen Kelly, Matthys H Botha, Frederick H Van der Merwe, Robyn A Adams, Jennifer L Butt, Johanna E Zwanepoel

“…All study procedures comply with the Declaration of Helsinki, South African Good Clinical Practice Guidelines and the Medical Research Council’s ethical guidelines. …”
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Non-pharmacological interventions for patients with axial spondyloarthritis: a meta-analysis by Lidong Hu, Xingkang Liu, Xiaojian Ji, Yiwen Wang, Jiaxin Zhang, Lulu Zeng, Yangqin Xun, Jianglin Zhang, Jian Zhu, Feng Huang

“…Background: Non-pharmacological interventions (NPIs) are recommended in current international clinical practice guidelines for the management of axial spondyloarthritis (axSpA) as a complementary therapy. …”
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Self-determined strategies for physical activity motivation among women with polycystic ovary syndrome by Pamela J. Wright, Cynthia Corbett, Bernardine M. Pinto, Michael D. Wirth, Robin M. Dawson

“…Background: According to clinical practice guidelines for polycystic ovary syndrome, first-line treatment includes performing 150 min of moderate-to-vigorous physical activity on most days of the week plus at least 2 days of resistance training. …”
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Effect of Training Eye Care Clinical Guideline for ICU Patients on Clinical Competence of Eye Care in Nurses by Zakieh Momeni Mehrjardi, Samaneh Mirzaei, Mohsen Gohari, Abbass Hafezieh, Khadijeh Nasiriani

“…The aim of the present study was to determine the effect of training EC clinical practice guidelines for ICU patients on nurses’ knowledge, attitude, and practice of EC. …”
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Methods for the early detection of drug-induced pancreatitis: a systematic review of the literature by Brian Hutton, David Moher, Becky Skidmore, Dianna Wolfe, Salmaan Kanji, Fatemeh Yazdi

“…Objectives We systematically reviewed the literature to identify evidence-informed recommendations regarding the detection of drug-induced pancreatitis (DIP) and, secondarily, to describe clinical processes for the diagnosis of DIP.Design Systematic review.Data sources Ovid MEDLINE, including Epub Ahead of Print, In-Process &amp; Other Non-Indexed Citations, Embase Classic+Embase, the Cochrane Library.Eligibility criteria We included clinical practice guidelines, systematic reviews, narrative reviews and observational studies with a focus of establishing incidence, prevalence or diagnostic approaches for DIP. …”
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Antibiotic use for acute respiratory infections among under-5 children in Bangladesh: a population-based survey by Jeffrey Braithwaite, Mohammad Riashad Monjur, Fahmida Chowdhury, Md Zakiul Hassan, Md Abdullah Al Jubayer Biswas, Mohammad Abdullah Heel Kafi

“…The significant prevalence of antibiotic exposure in under-5 children supports the need for coordinated policy interventions and implementation of clinical practice guidelines at point of care to minimise the adverse effects attributed to antibiotic overuse.…”
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Updated therapeutic options for human brucellosis: A systematic review and network meta-analysis of randomized controlled trials. by Shanjun Huang, Jiaying Xu, Hao Wang, Zhuo Li, Ruifang Song, Yiting Zhang, Menghan Lu, Xin Han, Tian Ma, Yingtong Wang, Jiaxin Hao, Shanshan Song, Qing Zhen, Tiejun Shui

“…<h4>Background</h4>In clinical practice guidelines, there is no consensus about the medications that should be initially offered to patients with brucellosis. …”
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Evaluating the utilisation patterns of pharmacological therapy in COVID-19 patients: an ecological study in Italy by Graziano Onder, Francesco Trotta, Maria Lucia Marino, Aurora Di Filippo, Davide Eleuteri

“…Backgound The drug central monitoring system set up in Italy to evaluate the real-time trends of medicines used in hospital and primary care settings contributed to inform drug supplies, avoided stockpiling and allowed to monitor adherence to clinical practice guidelines for the treatment of COVID-19 patients. …”
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Sustainable implementation efforts in physio- and occupational therapy: a scoping review by Johanna Fritz, Sara Landerdahl Stridsberg, Riikka Holopainen

“…The implementation of evidence-based methods in health care requires systematic support, but it is still unclear which strategies support professional adherence to clinical practice guidelines. Behavior change techniques can contribute to a more detailed description of implementation strategies. …”
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GABRINOX-2 protocol: a French, prospective, multicentre, randomised phase II trial evaluating gemcitabine/nab-paclitaxel followed by FOLFIRINOX versus FOLFIRINOX alone as first-lin... by Sophie Gourgou, Fabienne Portales, Marc Ychou, Catherine Fiess, Eric Assenat, Fanny Salasc

“…It will be carried out in accordance with European Reglementation 536/2014 on clinical trials, the Declaration of Helsinki, Good Clinical Practice guidelines and the French Public Health Code. …”
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Health professionals’ beliefs and attitudes towards preconception care: a systematic review by Cherie Caut, Danielle Schoenaker, Erica McIntyre, Amie Steel

“…Clinically relevant preconception information and clinical practice guidelines have since been developed to aid health professionals in preconception care delivery. …”
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QUALITY OF PATIENT’S LIFE AFTER MULTIPLE MYELOMAREGRESSION by Yu. M. Kolesnik, B. B. Samura

“…Methods: Subjects with full or partial remission of multiple myeloma were enrolled in the study.Diagnosis and staging of multiple myeloma were defined by current clinical practice guidelines. To be achieving remission chemotherapy with MPT, MP, CVP, PAD, VMPT, VADTD, CTD, VMP was used accordingly contemporary clinical guidelines. …”
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Stakeholders’ Perspectives on Quality Measurement of Oral Health Care in the Netherlands: A Qualitative Study by Amy Righolt, Denise Duijster, Kirsten Smits, Anke Oerlemans, Philip van der Wees, Stefan Listl

“…Facilitating factors were discussing quality in a trusted environment, and developing more clinical practice guidelines, which include meaningful quality measures. …”
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Rationale, design and objectives of two phase III, randomised, placebo-controlled studies of GLPG1690, a novel autotaxin inhibitor, in idiopathic pulmonary fibrosis (ISABELA 1 and... by Kevin K Brown, Toby M Maher, Michael Kreuter, David J Lederer, Wim Wuyts, Nadia Verbruggen, Simone Stutvoet, Ann Fieuw, Paul Ford, Walid Abi-Saab, Marlies Wijsenbeek

“…Key secondary endpoints are week 52 composite endpoint of disease progression or all-cause mortality (defined as composite endpoint of first occurrence of ≥10% absolute decline in per cent predicted FVC or all-cause mortality at week 52); time to first respiratory-related hospitalisation until end of study; and week 52 change from baseline in the St George’s Respiratory Questionnaire total score (a quality-of-life measure).Ethics and dissemination Studies will be conducted in accordance with Good Clinical Practice guidelines, Declaration of Helsinki principles, and local ethical and legal requirements. …”
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Comparison between intratympanic injection of dexamethasone and methylprednisolone in idiopathic sudden sensorineural hearing loss: A randomized clinical trial by Kourosh Eftekharian, Elnaz Najafi, Maryam Amizadeh, Noosheen Mokari, Mohammad Faramarzi, Yalda Izadparast, Yalda Jabbari Moghadam, Ali Eftekharian

“…Three comparisons between the initial and third‐month hearing tests were made to assess the degree of hearing change: (1) pure tone improvement in each individual tone (0.5, 1, 2, 3, and 4 kHz); (2) word‐recognition score improvement; and (3) complete, partial, and no recovery of hearing calculated (as defined by American Academy of Otolaryngology‐Head and Neck Surgery Clinical Practice Guidelines). Results The study was completed with 69 of the 75 patients—34 in the methylprednisolone group and 35 in the dexamethasone group. …”
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