Showing 81 - 100 results of 186 for search '"zebrafish"', query time: 0.08s Refine Results
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    A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafish. by Ugo Coppola, Bitan Saha, Jennifer Kenney, Joshua S Waxman

    Published 2024-11-01
    “…CRISPR-mediated deletion of the endogenous 3'reg1 abrogates the ability of Foxf1 and Wnt signaling to produce surplus ACs in zebrafish embryos. Together, our data support that downstream members of a conserved regulatory network involving Wnt signaling and Foxf1 function on a nr2f1a enhancer to promote AC differentiation in the zebrafish heart.…”
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  4. 84

    Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment by Katherine M. Ranard, Bruce Appel

    Published 2025-01-01
    “…Here, we create a novel DHA-deficient zebrafish model by 1) disrupting elovl2, a key gene in the DHA biosynthesis pathway, via CRISPR/Cas9 genome editing, and 2) feeding mothers a DHA-deficient diet. …”
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    Transcriptome analysis unveils the mechanisms of oxidative stress, immunotoxicity and neurotoxicity induced by benzotriazole UV stabilizer-328 in zebrafish embryos by Xinlu Yang, Yijing Gan, Menghuan Zhang, Shaolin Xie, Mingfu Lin, Lixiang Zhong, Mengke Song, Jun Wang, Yumei Huang

    Published 2025-02-01
    “…By measuring the growth and developmental indices, production of ROS, enzyme activities, MDA content and expression of genes related to oxidative, immune and nerve, and histopathological analysis, it was found that UV-328 had developmental toxicity to zebrafish larvae, and could induce oxidative stress, immunotoxicity and neurotoxicity to zebrafish larvae even at environmental concentrations with concentration-dependent effects. …”
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    Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters by Luiza Wilges Kist, Angelo Luis Piato, João Gabriel Santos da Rosa, Gessi Koakoski, Leonardo José Gil Barcellos, João Sarkis Yunes, Carla Denise Bonan, Maurício Reis Bogo

    Published 2011-01-01
    “…In this study, we assessed behavioral patterns and whole-body cortisol levels of adult zebrafish (Danio rerio) exposed to cell culture of the microcystin-producing cyanobacterium M. aeruginosa (MC-LR, strain RST9501). …”
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  10. 90

    Stability and Efficacy of Live-Attenuated Vibrio harveyi Vaccines Under Different Storage Conditions in Zebrafish (Danio rerio) Models by Mohd Hafiz Ngoo Muhamad-Sofie, Aslah Mohamad, Mohamad Azzam-Sayuti, Mohammad Noor Azmai Amal, Mohd Zamri-Saad, Md Shirajum Monir, Ina Salwany Md Yasin

    Published 2024-09-01
    “…Graphical Abstract Highlight Research • The LD50 (median lethal dose) of Vibrio parahaemolyticus and harveyi in zebrafish was determined to be 1 x 106 CFU/mL, while for V. alginolyticus it was found to be 1 x 105 CFU/mL…”
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  11. 91

    Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation by S.Z. Raduan, Q.U. Ahmed, M.R.A. Rusmili, A.S.M. Sabere, M.S. Haris, M.F. Shaikh, W.A.W. Sulaiman, M.H. Mahmood

    Published 2025-01-01
    “…Introduction/objectives: Alzheimer's disease (AD) is characterised by a progressive decline in cognitive abilities, especially learning and memory. To validate the zebrafish as a suitable model organism for AD, the study examined the effects of 2 neurotoxin agents, aluminium chloride (AlCl3) and okadaic acid (OKA). …”
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    Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish by Wang Lin, Ling Liao, Ling Ling, Huimin Luo, Ying Jiang, Xinru Li, Yilong Yao, Pinhong Yang

    Published 2025-02-01
    “…However, the presence of PSMPs disrupts this self-regulatory equilibrium, thereby exacerbates the thyroid endocrine disruption cause by MCLR in zebrafish.…”
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  16. 96

    Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

    Published 2007-01-01
    “…Keywords: desaturase, nutraceutical fatty acid, transgenic, zebrafish, masu salmon   Abstrak Promoter merupakan regulator yang menentukan tempat, waktu dan tingkat ekspresi gen.  …”
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