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521
RETRACTED: LncRNA CCAT2 promotes the proliferation and metastasis of colorectal cancer through activation of the ERK and Wnt signaling pathways by regulating GNB2 expression
Published 2024-09-01“…Functional analyses including CCK8, colony formation, wound healing migration, transwell chamber, and Muse® Cell Analyzer assays were performed to study the effects of CCAT2 gene deletion on CRC cells. …”
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522
Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice
Published 2025-02-01“…Both models showed significant reactive gliosis, suggesting comparable late-stage wound healing responses. These findings underscore the utility of these approaches for subretinal delivery, offering insights into their distinctive leukocyte infiltration and late-stage tissue responses.…”
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523
A Comprehensive Analysis of Moist Versus Non‐Moist Dressings for Split‐Thickness Skin Graft Donor Sites: A Systematic Review and Meta‐Analysis
Published 2025-01-01“…Hydrocolloid dressings were particularly effective in accelerating wound healing. Additionally, moist dressings were associated with lower pain levels during dressing removal and had comparable rates of adverse events. …”
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524
Prednisone inhibits osteosarcoma cell by regulating the Wnt/β-catenin signaling pathway
Published 2024-12-01“…To investigate the effect of prednisone on osteosarcoma cells in vitro, CCK8, wound healing, Transwell assays, flow-cytometry, western blot, and ELISA were used to measure cell proliferation, cell migration, cell invasion, cell cycle, cell apoptosis, and the key proteins in Wnt/β-catenin pathway. …”
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525
Scurvy as a Cause of Leg Pain and Limp in Pediatric and Adolescent Patients
Published 2025-02-01“…The resulting disease, known as scurvy, can present with various findings, including gingival bleeding, bruising, other skin lesions, poor wound healing, and tooth and bone abnormalities. VCD is also an uncommon cause of musculoskeletal pain among children. …”
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526
Functional Properties of Human-Derived Mesenchymal Stem Cell Spheroids: A Meta-Analysis and Systematic Review
Published 2021-01-01“…For instance, research exhibited reduced inflammation, faster wound healing, and closure, functional recovery and tissue repair due to immunomodulatory effects, better MSC engraftment in damaged tissue, higher MSC survival and less apoptosis at the injury. …”
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527
Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models
Published 2025-01-01“…Here, we established a series of VEGF-based computational docking analyses and cell models, such as a wound healing assay in HaCaT cells and an evaluation of NF-κB performance in macrophages, to screen a large library of flavonoid-type phytochemicals. …”
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528
Effect of preoperative immunonutrition on complications after salvage surgery in head and neck cancer
Published 2019-05-01“…Abstract Background Patients undergoing salvage surgery for recurrent head and neck squamous cell carcinoma are at high risk of postoperative complications due to the adverse effects of radiotherapy on wound healing. Malnutrition is an additional risk factor and we tested the hypothesis that preoperative administration of immunonutrition would decrease complications in this high risk population. …”
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529
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways
Published 2019-01-01“…Liver fibrosis is a consequence of wound-healing responses to chronic liver insult and may progress to liver cirrhosis if not controlled. …”
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530
Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential
Published 2016-01-01“…We also discuss the role of S1P-S1PR1 axis in inflammatory diseases and wound healing.…”
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531
Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance
Published 2013-12-01“…A radioresistant cell line was established by fractionated ionizing radiation (IR) and assessed by a clonogenic assay, flow cytometry, and Western blot analysis, as well as zymography and a wound healing assay. Microarray was performed to profile global expression and to search for differentially expressed genes (DEGs) in response to IR. …”
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532
KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA
Published 2024-12-01“…The migratory and invasive capabilities were evaluated utilizing wound healing and Transwell. Angiogenesis was assessed by ELISA, tube formation assay and western blot. …”
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533
hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways
Published 2025-01-01“…The anti-proliferative, anti-migratory, anti-invasive and pro-apoptotic effects of hERG activators were evaluated using the Cell Counting Kit-8, wound healing assay, transwell assay and cell apoptosis assay, respectively. …”
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534
Comparative Efficacy and Tolerability of Imiquimod 3.75% Cream vs 5-Fluorouracil 4% cream in the Treatment of Actinic Keratosis: A Split-Face Study
Published 2025-01-01“…Conclusions: This study reports a non-superiority of efficacy, tolerability, wound-healing time, and cosmetic outcome of topical IMQ 3.75% treatment compared to topical 5-FU 4% treatment in AK management. …”
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535
GGCT participates in the malignant process of hepatocellular cancer cells by regulating the PTEN/PI3K/AKT pathway through binding to EZH2
Published 2025-02-01“…Methods GGCT expression in HCC and its effect on patient survival curve in HCC were evaluated utilizing the UALCAN database, along with western blot. CCK-8, EdU, and wound healing, together with transwell and western blot assays were adopted to assess the capabilities of cells to proliferate, migrate, invade, and epithelial-mesenchymal transition (EMT). …”
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536
The potential of stem cell therapy in Multiple Sclerosis treatment: a review
Published 2023-12-01“…There are currently 371 clinical trials involving mesenchymal stem cells and 462 clinical trials involving adipose derived stem cells, with research focused on skeletal applications, wound healing, and to a lesser degree, haematological and neurological disorders. …”
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537
Lactoferrin: a secret weapon in the war against pathogenic bacteria
Published 2024-10-01“…Lf is a multifunctional glycoprotein with immunomodulatory, anticarcinogenic, wound-healing, antioxidant, antimicrobial, and bone regeneration properties, in addition to improving the gut microbiota. …”
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538
Therapy of Prostate Cancer by Nanoyam Polysaccharide
Published 2019-01-01“…The scratch adhesion test showed that the rate of wound healing in the intervention group was significantly lower than that in the control group (p<0.05). …”
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539
Antitumor Activity of Whole-Plant Extracts from In Vitro Cultured and Wild-Growing <i>Clinopodium vulgare</i> Plants on a Panel of Human Tumor Cell Lines
Published 2025-01-01“…The ability of <i>C. vulgare</i> to inhibit cancer cell migration and induce apoptosis in the tumor cells was examined by wound healing assay and fluorescence microscopic methods. …”
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540
Developing incisional hernia after open liver resection and liver transplantation: A single-center risk factor analysis
Published 2024-01-01“…Of course, many other risk factors may interfere with wound healing and can increase the risk of developing IH after this type of surgery. …”
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