Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on P... by Mpho Ndou, Marthe C. D. Fotsing, Michael H. K. Kengne, Edwin M. Mmutlane, Derek T. Ndinteh, Mthokozisi B.C. Simelane, Lesetja Motadi, Mpho Choene

“…Cell migration was assessed using wound healing. Alamar blue assay showed that the molecule studied exhibited antiproliferative activity on both the PaCa-2 and A375 cell lines, however, with higher cytotoxicity on PaCa-2 which suggests that it is cell-line dependent. …”
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Enhanced Expression and Bioactivity Assessment of Recombinant SUMO-Protease-1 in E. coli BL21 (DE3) via Cleavage of His6-SMT3-SDF-1 Fusion Protein by Farzad Sadri, Hossain Safarpour, Zahra Ansari, Yazdan Ebrahimpour, Mohammad Feriedouni

“…Enzymatic activity was shown by the effective cleavage of the His6-SUMO-SDF-1 fusion protein. In the scratch wound-healing assay, recombinant SDF-1 increased cell migration following cleavage, confirming that biological activity was retained. …”
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Everolimus in Heart Transplantation: An Update by Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, Hans B. Lehmkuhl

“…Caution about the use of everolimus immediately after transplantation should be exercised in certain patients with the risk of severe proteinuria, with poor wound healing, or with uncontrolled severe hyperlipidemia. …”
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Bio-orthogonal crosslinking and hyaluronan facilitate transparent healing after treatment of deep corneal injuries with in situ-forming hydrogels by Fang Chen, Uiyoung Han, Thitima Wungcharoen, Youngyoon Amy Seo, Peter Le, Li Jiang, Nae-Won Kang, Euisun Song, Kyeongwoo Jang, David Mundy, Gabriella Maria Fernandes-Cunha, Sarah Heilshorn, David Myung

“…Here we performed a direct, side-by-side comparison of a composite hyaluronan-collagen (HA-Col) hydrogel crosslinked by either photochemistry or bio-orthogonal chemistry to ascertain the impact of reaction specificity on corneal wound healing. Testing in rodent and rabbit models suggests that composite HA-Col gels crosslinked by bio-orthogonal chemistry results in more rapid and optically favorable wound healing compared to the same composition crosslinked by photochemistry as well as bio-orthogonally crosslinked collagen alone. …”
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Vacuum-Assisted Closure and Muscle Flap as An Alternative Modality for Infected Wound After Orif of Tibial Fracture: Case Report by OK Ilham Abdullah Irsyam, Saraswati Hastika, Hendra Hendra, Andrew Budiartha Budisantoso, Tesar Akbar Nugraha

“…This finding was associated with accompanying morbidities or a good wound healing process.…”
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Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes by Flavia Bruna, David Contador, Paulette Conget, Benjamín Erranz, Claudia L. Sossa, Martha L. Arango-Rodríguez

“…No systematic information is currently available regarding whether donor age modifies MSC regenerative potential on cutaneous wound healing. Here, we evaluate whether donor age influences this potential. …”
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Therapeutic Effect of Zataria Multiflora Essential Oil on Burn Wound Infected by Pseudomonas aeruginosa by Maryam Zare, Elahe Sattarinezhad, Ali Karimi Akhormeh, Maryam Motevasel, Marzieh Ashrafmansouri, Maral Mokhtari, Omid Koohi Hosseinabadi, Aida Iraji, Azar Purkhosrow

“…This study was designed to investigate antibacterial and wound healing effects of Zataria multiflora essential oil (ZMEO) on burn wounds infected with P. aeruginosa in Sprague-Dawley rats. …”
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Application of suture-stretching technique in repairing skin defect of lower limb by Yuan Pan, Yingying Deng, Chaoran Hu, Kunzhi Zhu, Chao Feng

“…We collected the data of the two groups, including wound size, number of debridements, operation time, wound healing time, hospital stays, and surgury cost, and the data were analyzed statistically. …”
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Biosynthesis of Silver Nanoparticles and Its Applications by M. Jannathul Firdhouse, P. Lalitha

“…Silver nanoparticles possess unique properties which find myriad applications such as antimicrobial, anticancer, larvicidal, catalytic, and wound healing activities. Biogenic syntheses of silver nanoparticles using plants and their pharmacological and other potential applications are gaining momentum owing to its assured rewards. …”
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The Efficacy of Platelet-Rich Plasma in the Repair of Tympanic Membrane Perforation by Kudure Basavaraj Prashanth, Haraganahalli Anandappa Manjunatha, Prathvi P. Nayak

“… Introduction Platelet-rich plasma (PRP) contains high platelet concentration and growth factors that help in rapid wound healing, hemostasis, and decreased scarring. It has been used in various conditions to aid in healing, but its use in ear, nose, and throat (ENT) is not yet common.…”
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A novel approach for managing the incisions of tibial plateau fractures with soft tissue swelling by Yang Zhang, Yangyang Zhao, Shuanggong Liu, Zihan Yao, Zikang Jin, Wanli Ma

“…There were no significant differences in one-stage operation time, intraoperative blood loss, or wound healing time between the two groups (P > 0.05). …”
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Stimulative Effects of Low Intensity He-Ne Laser Irradiation on the Proliferative Potential and Cell-Cycle Progression of Myoblasts in Culture by Cui-Ping Zhang, Shao-Dan Li, Yan Chen, Yan-Ming Jiang, Peng Chen, Chang-Zhen Wang, Xiao-Bing Fu, Hong-Xiang Kang, Ben-Jian Shen, Jie Liang

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Stryphnodendron adstringens have a modulatory effect on inflammatory cytokines markers of in vitro activated macrophages by Ivana Beatrice Mânica da Cruz, Cibele Ferreira Teixeira, Neida Luiza Pellenz, Moisés Henrique Mastella, Verônica Farina Azzolin, Euler Esteves Ribeiro, Fernanda Barbisan

“….; S. adstringens), a Brazilian wound-healing plant, on the expression of inflammatory cytokines. …”
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Encapsulation of Hydrogen Peroxide in PVA/PVP Hydrogels for Medical Applications by Natalie Mounayer, Sivan Shoshani, Elena Afrimzon, Taly Iline-Vul, Moris Topaz, Ehud Banin, Shlomo Margel

“…These findings support further in vivo investigation into controlled HP release systems for improved wound-healing outcomes.…”
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Comparative analysis of viability, proliferation, and mineralization potential of human pulp and osteoblastic cells exposed to different bioceramic endodontic sealers by Marcos Coelho Santiago, Gustavo Henrique de Oliveira Salles, Gustavo Gomes de Lima, Laudimar Alves de Oliveira, Loise Pedrosa Salles

“…Statistical analysis was performed using Two-way ANOVA for calcium release and wound healing assays and One-way ANOVA for other assays, with post-test Bonferroni correction. …”
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A human acellular dermal matrix coated with zinc oxide nanoparticles accelerates tendon repair in patients with hand flexor tendon injuries in zone 5 of the hand by Seyedeh-Sara Hashemi, Mohsen Pirmoradi, Alireza Rafati, Mehdi Kian, Ali Akbar Mohammadi, Mohamad Ali Hoghoughi

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Blastocyst-Derived Lactate as a Key Facilitator of Implantation by Kathryn H. Gurner, David K. Gardner

“…While historically perceived as a metabolic waste product, lactate serves as a signaling molecule which facilitates the invasion of surrounding tissues by cancers and promotes blood vessel formation during wound healing. However, the role of lactate in reproduction, particularly at the implantation site, is still being considered. …”
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Hydrolyzed Collagen from Salmon Skin Increases the Migration and Filopodia Formation of Skin Keratinocytes by Activation of FAK/Src Pathway by Wanwipha Woonnoi, Lalita Chotphruethipong, Supita Tanasawet, Soottawat Benjakul, Nuthathai Sutthiwong, Wanida Sukketsiri

“…Keratinocyte migration and filopodia formation were measured by wound healing assay and phalloidin‐rhodamine staining, respectively. …”
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Analgesic efficacy and safety of methylene blue combined with cocktail for periarticular infiltration following total knee arthroplasty: a prospective, randomized, controlled study by Yijiang Deng, Yong Yang, Feng Zhu, Wenzhi Liu, Jiarui Chen, Guangmin Xu

“…Then, the rest and movement Numeric Rating Scale (NRS) scores, postoperative sufentanil consumption, postoperative inflammatory markers, and the occurrence of adverse reactions such as wound infection and poor wound healing were compared after postoperative 24 h, 48 h, 72 h, and 7-day, 14-day, 28-day between the two groups. …”
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights by Lingxia Wu, Chenxiaoxiao Liu, Weicai Hu

“…Functional assays, including cell proliferation, colony formation, and wound healing, were conducted post-MMP7 knockdown using siRNA in A375 cells. …”
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