Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy by Hemanathan Vembuli, Sheeja Rajasingh, Patrick Nabholz, Jefferson Guenther, Brian R. Morrow, Margaret M. Taylor, Marziyeh Aghazadeh, Vinoth Sigamani, Johnson Rajasingh, Johnson Rajasingh, Johnson Rajasingh

“…However, their limited differentiation capacity and wound healing abilities necessitate the exploration of alternative cell sources. …”
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Characterization of Pseudomonas aeruginosa Isolates Obtained from Patients in Canadian Hospitals: Results of the CANWARD 2007 Study by Andrew Walkty, Melanie DeCorby, Kim Nichol, Melissa McCracken, Michael R Mulvey, James A Karlowsky, Daryl J Hoban, George G Zhanel

“…Each centre was asked to submit clinical isolates (consecutive, one per patient per infection site) from blood (n=360), respiratory (n=200), urine (n=100) and wound/intravenous (n=50) infections. Susceptibility testing was performed using Clinical and Laboratory Standards Institute broth microdilution methods. …”
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Evaluating the Effectiveness, Safety, and Satisfaction Rates of Phenol 90%, Trichloroacetic Acid 100%, and Radiofrequency in Lateral Matricectomy for the Treatment of Ingrown Toena... by Mohammadreza Ghassemi, Zahra Keshavarz, Elham Behrangi, Afsaneh Sadeghzadeh Bazargan, Alireza Jafarzadeh, Azadeh Goodarzi

“…Pain levels were measured using the Visual Analog Scale (VAS), while wound discharge and bleeding were rated on specified scales. …”
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Construction and validation of prognosis and treatment outcome models based on plasma membrane tension characteristics in bladder cancer by Zhipeng Wang, Sheng Li, Fuchun Zheng, Situ Xiong, Lei Zhang, Liangwei Wan, Chen Wang, Xiaoqiang Liu, Jun Deng

“…Biological functions were investigated using a series of experiments including quantitative reverse transcriptase polymerase chain reaction (qRT-PCR), wound healing, transwell, etc. Results Our MTRG score is based on eight genes (HTRA1, GOLT1A, DCBLD2, UGT1A1, FOSL1, DSC2, IGFBP3 and TAC3). …”
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Perioperative outcomes of video-assisted versus right anterior thoracotomy mitral valve replacement: an observational study by Gehad Awad, Fetoh Alaaeldin Fetoh, Noureldin Noaman Gwely, Usama Hamza, Sameh Amer, Yomna Mohammed Yehya, Amr Abdellateef

“…Results Intraoperative parameters showed no statistical difference between the two groups. Wound length in the VAMVR group was statistically smaller than the ATMVR group, 5.33 ± 0.96 cm versus 7.08 ± 1.24 cm, respectively (P < 0.001). …”
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Outcome of Pleural Empyema Treated With Video-Assisted Thoracoscopic Surgery in Patients With Severe Co-Morbidities: An Observational Study by Vu HA, Nguyen NV, Le TD, Nguyen ST, Viet Le A, The Vu A, Van Nguyen B, Van Nguyen B, Thanh Quan N, An NV, Duc Nghiem T

“…The surgery procedures were efficient with a short duration (65.6 ± 9.4 minutes), low incidence of blood transfusion (8.3%), and lower rate of postoperative complications (surgical wound infection 8.3%). The length of postoperative stay was 16.8 ± 9.9 days. …”
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What Is the Best Proximal Anastomosis for the Free Right Internal Thoracic Artery during Bilateral Internal Thoracic Artery Revascularization? A Prospective, Randomized Study by S. Neragi-Miandoab, R. E. Michler, F. Lalezarzadeh, R. Bello, J. J. DeRose

“…Thirty-day mortality and wound infection were 0% for each group. Over an average of 42.8+6.6 months of followup there were no mortalities in either group. …”
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MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1 by Kaiqiang Meng, Jian Song, Fan Qi, Jiamin Li, Zhichao Fang, Liang Song

“…Exploring the biological functions of MT1G overexpressing GC cell lines through wound healing and transwell experiments. Use specific fluorescence probes to examine mitochondrial membrane potential and Fe2+ fluorescence intensity. …”
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MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation by Yi Zhang, Qin-shan Li, Hong-lin Liu, Hong-ting Tang, Han-lin Yang, Dao-qiu Wu, Yu-ying Huang, Li-cheng Li, Li-hong Liu, Meng-xing Li

“…The impact of MKRN1 on CRC cell proliferation and migration was observed using CCK8, colony formation, wound healing, and transwell assays. A combination of MKRN1 quantitative proteomics, ubiquitination modification omics analysis, and a string of in vitro and in vivo experiments revealed the potential mechanisms by which MKRN1 regulates CRC metastasis. …”
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Therapeutic potential of adipose-derived stem cells for diabetic foot ulcers: a systematic review and meta-analysis by Mohamed A. Abu Elainein, Mohamad Mahmoud Whdan, Mahmoud Samir, Nada G. Hamam, Mohamed Mansour, Mohamed Abdel Mohsen Mohamed, Mahmoud Mostafa Snosy, Mahmoud Ayman Othman, Ahmed Sayed Sobieh, Mahmoud Gamal Saad, Mohamed A. Labna, Salma Allam

“…Conventional treatments such as traditional dressings often fall short in ensuring satisfactory wound healing, this Meta-analysis investigates the therapeutic potential of Adipose-derived Stem Cells (ADSCs) as a promising strategy for addressing this challenge. …”
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Evaluation of the merit of ethanolic extract of Annona reticulata as an anti-cancer agent in human colon cancer cell lines (HCT-116) [version 2; peer review: 2 approved, 1 not appr... by Sri Pragnya Cheruku, Krishnananda Prabhu, Akshatha G Nayak, Vijetha Shenoy Belle, Vanishree Rao, Pooja Prakash Rao, Nitesh Kumar

“…The anti-migratory effect was studied using a scratch wound healing assay. Gas chromatography-mass spectrometry (GC-MS) was done to identify the major phytocompounds present in the fraction. …”
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Anti-TNBC effects of Lappaol F by targeting epithelial-mesenchymal transition via regulation of GSK-3β/YAP/β-catenin and PI3K/AKT pathways by Qiqi Meng, Qiqi Meng, Zhiping Li, Xiaofeng He, Yuanhao Hu, Guiyun Wu, Jiawen Huang, Zhuohui Luo, Zhuohui Luo, Yingjie Hu, Xiaoling Shen

“…The present study aimed to reveal the potential mechanism of LAF against TNBC by in vivo and in vitro experiments.MethodsIn situ, transplantation-induced MDA-MB-231 solid tumor model in NCG mice and cultured MDA-MB-231 and Hs-578T cells were used to evaluate the anti-TNBC effect of LAF. Flow cytometry, wound healing, transwell assay, western blot, RT-PCR, and immunofluorescence analysis were carried out to investigate the pharmacological mechanism of LAF against TNBC.ResultsLAF significantly inhibited the growth of MDA-MB-231 tumors, with downregulated tumor level of vimentin and upregulated level of ZO-1. …”
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MANAGING MAXILLARY BONE LOSS USING GROWTH FACTORS IN PRE-IMPLANT THERAPY by Cardas Adelina, Stratan Ion, Moraru Daliana, Tibeica Andreea, Agop-Forna Doriana, Norina Forna

“…These factors are pivotal in promoting wound healing, angiogenesis, and the formation of the extracellular matrix. …”
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Strategic Infectious Diseases in Beef Cattle in Balongpanggang during 2023 by Wiwik Misaco Yuniarti, Bambang Sektiari Lukiswanto, Boedi Setiawan, Ira Sari Yudaniayanti, Nusdianto Triakoso, Mirza Atikah Madarina Hisyam, Lina Susanti, Apriliwiyani Niken Hastuti, Budi Santoso Sudjono

“…In addition to BEF, official veterinary services reported a total case of 1546 throughout 2023 that comprises; diarrhea (99), limping (24), helminthiasis (91), ectoparasite (11), hematochezia (3), wound (3), mastitis (4), allergy (1), dystocia (28), vaginal prolapse (11), dermatitis (45), enteritis (27), tympani (11), scabiosis (122), arthritis (67), ophthalmic problem (11), endometritis (1), uterine retention (13), indigestion (2), pneumonia (21), hypoglycemia (5), abscess (21), ovariohysterectomy (1), orchitis (1), intoxication (1), and papilloma (1). …”
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Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells by Qi Zhao, Qi Zhao, Qi Zhao, Yan Zhang, Yan Zhang, Jieyu Liu, Peipei Chen, Annabeth Onga, Namki Cho, Ri Cui, Chenguo Zheng

“…Consequently, the search for anti-cancer components with high efficacy and low cytotoxicity has become a significant focus in recent years.MethodsThe anti-tumor effects of PD, OXA or their combination were assessed by cell viability, colony formation, and wound-healing assays. Reactive oxygen species (ROS) generation was measured by flow cytometry and DNA damage was assessed by immunofluorescence assay. …”
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Impact of re-operation on progression-free survival in patients with recurrent GBM: Experience in a tertiary referral center. by Houssein Darwish, Tasnim Diab, Sarah Kawtharani, Mounir Barake, Bader Ali, Nagham Ramadan, Hiba Fadlallah, Jeannot Kekedjian, Marwan Najjar, Hazem I Assi

“…The most common complications following both initial and subsequent surgeries included DVT, weakness, seizures, and wound leakage and infection. The progression-free survival for patients who underwent reoperation was 15.9 months, whereas for those who did not undergo reoperation, it was 6.7 months (log-rank p < 0.001) The median post progression survival for patients who underwent reoperation upon recurrence was 5.9 months, compared to 5.1 months for those who did not undergo reoperation. …”
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The Fabrication and Evaluation of a Potential Biomaterial Produced with Stem Cell Sheet Technology for Future Regenerative Medicine by Shukui Zhou, Ying Wang, Kaile Zhang, Nailong Cao, Ranxing Yang, Jianwen Huang, Weixin Zhao, Mahbubur Rahman, Hong Liao, Qiang Fu

“…However, the acellular matrix derived from natural tissues and organs has a lot of defects, including the limited amount of autogenous tissue and surgical complication such as risk of blood loss, wound infection, pain, shock, and functional damage in the donor part of the body. …”
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The burden and outcomes of firearm injuries at two district-level emergency centres in Cape Town, South Africa: A descriptive analysis by L Bush, C Hendrikse, C Van Koningsbruggen, K Evans

“…A total of 520 (67%) patients self-presented, and there were 18 (2.3%) deaths in the emergency centre and a further 23 (3%) as inpatients. Of the total where wound location was determined (n=595), 30.4% sustained more than one firearm injury, and 112 out of the 167 admitted to Mitchells Plain Hospital required at least one visit to theatre. …”
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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells by Zeynab Vakili-Ghartavol, Hoda Deli, Amir Shadboorestan, Roxana Sahebnasagh, Elahe Motevaseli, Mohammad Hossein Ghahremani

“…The effects of exosomes on parental cells were examined using various methods, including MTT assay for proliferation, wound healing assay for migration, flow cytometry for cell cycle and apoptosis analysis, Matrigel-coated transwell inserts for invasion, and western blot for integrin expression evaluation. …”
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