Effect of soil-groundwater system on migration and transformation of organochlorine pesticides: A review by Haohao Li, Lin Huo, Rui Zhang, Xuefan Gu, Gang Chen, Ying Yuan, Wenbing Tan, Kunlong Hui, Yu Jiang

“…Soil and groundwater are important strategic resources highly valued by countries around the world. However, in recent years, the deterioration of the ecological environment of soil-groundwater caused by industrial, domestic, and agricultural pollution sources has continued to threaten human health and ecological security. …”
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Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes: protocol for a nati... by François Schiele, Mikael Mazighi, Nicolas Danchin, Igor Sibon, Gilles Lemesle, Kamel Mohammedi, Laurent Fauchier, Bruno Detournay, Alexandre Caron, Corinne Emery, Camille Nevoret, Lucile Vigié, Christine Massien

“…However, the strict requirements of randomised controlled trials to avoid most confounding factors are at the expense of external validity. Using national real-world data, we aimed to evaluate the effectiveness of GLP-1RAs in association with metformin especially on cardiovascular events, hospitalisation for heart failure and all-cause death in comparison with other diabetes treatment schemes using dipeptidyl peptidase IV inhibitors, sulfonylureas/glinides or insulin also associated with metformin. …”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…Associations for other previously reported drugs (25/36) were not detected.Conclusions and relevanceThis study represents a comprehensive evaluation of suspected drug triggers of pemphigus using real-world data. The significant associations reported here provide empirical support for the hypothesis that certain drugs act as triggers for PV. …”
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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

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Identification of potential corticosteroid binding sites on the SARS CoV-2 main protease Mpro — in silico docking study by Н. В. Хміль, А. В. Шестопалова, В. Г. Колесніков, А. О. Боєчко-Немовча

“…Background: Currently, an increase in the number of new cases of Covid-19 caused by the severe acute respiratory syndrome virus (SARS-CoV-2) is recorded in Ukraine and the world. SARS-CoV-2 provokes exacerbation of chronic diseases and activates inflammatory and allergic reactions. …”
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Characteristics and outcomes of patients with LAM receiving sirolimus in France based on real-life data by Vincent Cottin, Vincent Cottin, Antoine Cases, Virginie Bourdin, Martine Reynaud-Gaubert, Sandrine Hirschi, Mallorie Kerjouan, Rémi Diesler, Rémi Diesler, Brieux Chardès, Stéphane Fiévez, Nada Assi, Aurélie Schmidt, Hélène Denis, Lidwine Wémeau-Stervinou, Yurdagul Uzunhan

“…Even though some of the results should be interpreted cautiously in the light of limitations related to the use of claims database, evolution of the disease and missing safety data, the information retrieved in this study is very valuable, as few studies provide real-world information on LAM populations.…”
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Physical and Sensory Long-Term Disabilities from <i>Bothrops</i> Snakebite Envenomings in Manaus, Western Brazilian Amazon by Eduardo M. G. Fernández, Débora N. Oliveira, Alexandre V. Silva-Neto, Rafaela N. Dávila, Ligia Lengler, Marco A. Sartim, Altair S. Farias, Luiz C. L. Ferreira, Érica da Silva Carvalho, Fan H. Wen, Felipe Murta, Fernando Almeida-Val, Manuela B. Pucca, Jacqueline A. G. Sachett, Wuelton M. Monteiro

“…Assessment of disability was also performed using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). …”
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Performance of a hybrid capture-based target enrichment next-generation sequencing for the identification of respiratory pathogens and resistance-associated genes in patients with... by Wei-Yu Hsu, Ting-Wei Kao, Hsin-Ching Cho, Sheng-Yuan Ruan, Tai-Fen Lee, Yu-Tsung Huang, Jung-Yien Chien

“…The study facilitated the implementation of molecular diagnosis by presenting real-world data, whereas future studies are mandated to generalize such an approach toward different clinical settings.…”
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Megagrazer loss drives complex landscape-scale biophysical cascades by Olli Hyvarinen, Mariska te Beest, Elizabeth le Roux, Graham I H Kerley, Robert Buitenwerf, Dave J Druce, Jiquan Chen, Linda Rapp, Joana Fernandes, Joris P G M Cromsigt

“…Leveraging a unique, ecosystem-scale, semi-experimental approach, we study how the local removals of the world’s largest, terrestrial grazer, white rhinoceros ( Ceratotherium simum ), affected the coupling between fire dynamics, woody encroachment and surface albedo in Hluhluwe–iMfolozi Park (HiP), South Africa. …”
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Impactos ambientales en la ciudad de Manaus: una búsqueda de comprensión Ambient impacts in the city of Manaus: an understanding search by Eveline Maria Damasceno do Nascimento, Iraildes Caldas Torres

“…It is essential to articulate the search for political, cultural, social, and educational vision that comprise the world of the residents living around the municipal park of Mindu. …”
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Sources of right to freedom of peaceful assembly by М. А. Sambor

“…It is in such treaties that the world community, humanity, has recognized the right of each person to the right to freedom of peaceful assembly, to freedom of exercise and to the exclusivity of grounds for restricting the exercise of the right to freedom of peaceful assembly. …”
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Modeling Portfolio Optimization based on behavioral Preferences and Investor’s Memory by vahideh mousavi kakhki, Sanaz Khatabi

“…However, these models often fail to capture the complexities of real-world investment decisions, which are often influenced by behavioral factors. …”
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The Impact of Bacterial Leaf Blight Disease (<i>Pantoea agglomerans</i>) on Grain Yield and Nutritional Quality of Oat by Ruochen Zhang, Jianjun Wang, Longhai Xue, Malik Kamran, Yue Wang, Xuekai Wei, Guiqin Zhao, Chunjie Li

“…As an important cereal and feed crop, oat has significant economic value and is widely cultivated throughout the world. However, leaf diseases have become a crucial factor limiting the increase in oat grain yield and the optimization of its nutritional quality. …”
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Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000 by Aleksandar M. Kostov, Maj-Britt Jensen, Bent Ejlertsen, Mads Thomassen, Caroline Maria Rossing, Inge S. Pedersen, Annabeth H. Petersen, Lise Lotte Christensen, Karin A.W. Wadt, Anne-Vibeke Lænkholm

“…This observational cohort study presents real-world data on BRCA testing within the context of clinical practice challenges, including incomplete family history and under-referral. …”
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Three different methods for ZnO-RGO nanocomposite synthesis and its adsorption capacity for methylene blue dye removal in a comparative study by Safaa A. Hussein, Gharib M. Taha, F. A. Adam, Marwa A. Moghazy

“…However, due to rapid industrialization, urbanization and lack of awareness, the world population now facing the threat of water shortage. …”
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Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in... by Imran Khan, Stephanie J. C. Taylor, Clare Robinson, Elisavet Moschopoulou, Paul McCrone, Liam Bourke, Mohamed Thaha, Kamaldeep Bhui, Derek Rosario, Damien Ridge, Sheila Donovan, Ania Korszun, Paul Little, Adrienne Morgan, Olivier Quentin, Rebecca Roylance, Peter White, Trudie Chalder

“…Registered on 09 December 2019. All items from the World Health Organization Trial Registration Data Set for this protocol can be found in Additional file 2 Table S1.…”
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Pengaruh Hiperglikemia terhadap Gambaran Histopatologis Pulau Langerhans Mencit by Muhammad Farid, Eryati Darwin, Delmi Sulastri

“…<br />Kata kunci: hiperglikemia, pulau Langerhans, gambaran histopatologis</p><p>Abstract</p><p>Diabetes mellitus become a serious health threat which prevalence have been increasing steadily all over the world. With complex interactions of risk factors on the disease, therapeutic approach of diabetes still centered on preventive measures and diagnosis was made entirely from the presence of hyperglycemia. …”
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A Comparative Study of the Reasons for the Persistence of Buddhism and the Decline of Zoroastrianism in Ancient China by Amin Yazdkhasti, Hamidreza Pashazanous

“…Buddhism with its pacifist and conservative approach, institutionalized the principle of accepting the concept of suffering as a reality in the world and offered the Chinese people what they wanted and remained in this land. …”
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Lung function improvement on triple modulators: high-resolution, nationwide data from the Danish Cystic Fibrosis Cohort by Christian Leo-Hansen, Daniel Faurholt-Jepsen, Tavs Qvist, Christine Højte, Bibi U. Nielsen, Thomas Bryrup, Esben H. Henriksen, Terese Katzenstein, Marianne Skov, Inger H.M. Mathiesen, Majbritt Jeppesen, Søren Jensen-Fangel, Hanne V. Olesen, Frederik Fouirnaies Buchvald, Kim Gjerum Nielsen, Espen Jimenez-Solem, Christian Ritz, Tacjana Pressler, Mette F. Olsen, the TransformCF Study Group

“…Conclusions Using high-resolution data from a nationwide real-world setting, our study documents the impact of elexacaftor/tezacaftor/ivacaftor on lung function across subgroups based on age, disease severity and treatment history. …”
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Pengaruh Pemberian Kopi Instan Oral Terhadap Kadar Asam Urat pada Tikus Wistar by Fauzan Arisyi Koto, Husnil Kadri, Zelly Dia Rofinda

“…<br />Kata kunci: kopi, polifenol, asam urat serum</p><p>Abstract<br />Coffee is one of the most frequently consumed beverages in the world. Many studies have examined the effect of coffee consumption on a wide range of specific medical condition. …”
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