Lynch Syndrome—Impact of the Type of Deficient Mismatch Repair Gene Mutation on Diagnosis, Clinical Presentation, Surveillance and Therapeutic Approaches by Tudor Razvan Grigorie, Gheorghe Potlog, Sorin Tiberiu Alexandrescu

“…In today’s world, with its continuing advancements in genetics, the identification of Lynch syndrome (LS) increasingly relies on sophisticated genetic testing techniques. …”
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The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper by H Finlayson, V Chibabhai, P Jeena, S Kolman, W Lowman, T C Manzini, T Nana, J Nuttall, A Parker, P Skosana, V Ueckermann, A Wise

“…It is increasing in both the public and private healthcare sectors within South Africa, especially in Gram-negative organisms, and is associated with increased use of World Health Organization watch and reserve antibiotics. …”
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Intra-uterine Growth Restriction Downregulates the Hepatic Toll Like Receptor-4 Expression and Function by Ozlem Equils, Sapna Singh, Semra Karaburun, Daning Lu, Manikkavasagar Thamotharan, Sherin U. Devaskar

“…Maternal starvation is a significant cause of intrauterine growth restriction (IUGR) in the world and increases the risk of infection in the neonate. …”
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Prevalence of the polymorphic H-ficolin (FCN3) genes and mannosebinding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions by M. V. Smolnikova, S. Yu. Tereshchenko

“…Analysis of the prevalence of the MASP2 genotypes has shown the predominance of the homozygous variant AA in all studied populations, which agrees with the available world data. The heterozygous genotype AG rs72550870 associated with a reduced level of protease was found to occur rarely in the Nenets, Dolgans and Nganasans compared to newborns of Caucasoid origin from Krasnoyarsk: 0.5 % versus 3.3 %, respectively. …”
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Characteristic and flavor profiles of specialty Arabica coffee derived from fermentation with protease, at different conditions by Wongyai Intugon, Suttisintong Khomson, Thumthanaruk Benjawan, Foophow Tita, Yasutomo Tamaki, Rungsardthong Vilai

“…Coffee is one of the most popular beverages in the world. Development of coffee beans with specific flavor profiles can enhance the quality and value of the product. …”
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The Potential Use of Mesenchymal Stem Cells and Their Derived Exosomes as Immunomodulatory Agents for COVID-19 Patients by Faisal A. Alzahrani, Islam M. Saadeldin, Abrar Ahmad, Dipak Kumar, Esam I. Azhar, Arif Jamal Siddiqui, Bassem Kurdi, Abdulrahim Sajini, Abdulmajeed F. Alrefaei, Sadaf Jahan

“…A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) causing lethal acute respiratory disease emerged in December 2019. The World Health Organization named this disease “COVID-19” and declared it a pandemic on March 11, 2020. …”
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Fermented soil amendments made from stabilized biosolids and fly ash improve maize (Zea mays L.) nutrition and growth by Karla E. Cortés-Tello, Pablo F Jaramillo-López

“…These two components were included because they are generated in large amounts and represent an environmental problem all over the world. Additionally, these materials have high concentrations of nutrients, but they have not been widely used because they also contain traces of heavy metals.…”
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Use of healthcare services during the COVID-19 pandemic in urban Ethiopia: evidence from retrospective health facility survey data by Getnet Alemu, Arjun S Bedi, Zemzem Shuka, Anagaw Mebratie, Matthias Rieger

“…The results underline the resilience and agility displayed by one of the world’s most resource-constrained healthcare systems. …”
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Development of measures to assess listening-related effort and fatigue in daily life among hearing aid users: protocol for a quantitative field trial by Trine Flensborg-Madsen, Andreea Micula, Jeppe Høy Konvalinka Christensen, Dorothea Wendt, Hamish Innes-Brown, Ingrid Johnsrude, Matthew Apps, Torsten Dau

“…However, there is a lack of objective measures to evaluate these experiences in real-world settings. Recent studies have found that higher sound pressure levels (SPL) and lower signal-to-noise ratios (SNR) are linked to increased heart rate and decreased heart rate variability, reflecting the greater effort required to process auditory information. …”
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Prognosis of invasive encapsulated follicular variant and classical papillary thyroid carcinoma: a propensity score-matched study using the SEER database by Shuai Jin, Lang Xie, Gongyou Zhang, Lei Liu, Kaide Xia, Hongzhou Liu, Haiwang Zhang, Peng Li

“…Abstract The latest World Health Organization Classification of Tumors, Fifth Edition, recognizes the invasive encapsulated follicular variant of papillary thyroid carcinoma (IEFVPTC) as a distinct malignant entity rather than a subtype of papillary thyroid carcinoma (PTC). …”
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Assessment of the potential and application of Be12O12 nanocage for removal of ciprofloxacin from water employing density functional theory by Qaisar Ali, Abdul Shakoor, Gul Rehman, Munir Ur Rehman, Momin Khan, Rashid Ahmad, Iftikhar Ahmad, Abdullah F. AlAsmari, Fawaz Alasmari

“…Abstract The modern world is facing the issue of emerging pollutants for its sustainable development. …”
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Sunflower lines originated from varieties with high oil content in their seed by V. A. Gavrilova, I. N. Anisimova, T. G. Stupnikova

“…Soviet varieties formed the basis for the world's sunflower breeding, and further for breeding commercial hybrids using the effect of heterosis. …”
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Investigation of sensory attenuation in the somatosensory domain using EEG in a novel virtual reality paradigm by Gianluigi Giannini, Till Nierhaus, Felix Blankenburg

“…Abstract We are not only passively immersed in a sensorial world, but we are active agents that directly produce stimulations. …”
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Does Health System Responsiveness Differ between Insured and Uninsured Outpatients in Primary Health Care Facilities in Asagirt District, Ethiopia? A Cross-Sectional Study by Wubshet Debebe Negash, Asmamaw Atnafu, Desale Bihonegn Asmamaw, Chalie Tadie Tsehay

“…Responsiveness was measured using the short version of the World Health Organization’s multicountry responsiveness survey, which has seven dimensions including autonomy, communication, confidentiality, attention, dignity, choice, and amenities. …”
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Induction of labour outcomes in a tertiary hospital: the Ghanaian cervix and misoprostol 25ug (GCAM-25 STUDY)—a cross-sectional study by Teresa Aba Mensah, Kwaku Asah-Opoku, Kwame Adu-Bonsaffoh, Evans Kofi Agbeno

“…Abstract Background Induction of labour is an indispensable obstetric procedure, although associated with some complications. The World Health Organization recommends the use of low dose misoprostol to reduce adverse induction outcomes like uterine hyperstimulation and rupture. …”
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Systematic development of quality indicators for skin cancer management in primary care: a mixed-methods study protocol by Frances Rapport, Jeffrey Braithwaite, Anne E Cust, David Wilkinson, Andrea Smith, Bela Ines Laginha

“…Introduction Australia has the highest incidence of skin cancer in the world, with two out of three Australians expected to be diagnosed with skin cancer in their lifetime. …”
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Detecting centennial changes in the clarity and colour of the Red and Eastern Mediterranean Seas by retracing the “Pola” expeditions by Jonathan R. Heath, Robert J. W. Brewin, Jaime Pitarch, Dionysios E. Raitsos

“…The world’s oceans and seas are changing rapidly due to several natural and anthropogenic reasons. …”
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The PDC30 Chatbot—Development of a Psychoeducational Resource on Dementia Caregiving Among Family Caregivers: Mixed Methods Acceptability Study by Sheung-Tak Cheng, Peter H F Ng

“…Chatbot-B was constructed using PDC30 Chatbot’s architecture but replaced the latter’s knowledge base with a collection of authoritative sources, including the World Health Organization’s iSupport, By Us For Us Guides, and 185 web pages or manuals by Alzheimer’s Association, National Institute on Aging, and UK Alzheimer’s Society. …”
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Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology by Matteo P. Ferla, Rubén Sánchez-García, Rachael E. Skyner, Stefan Gahbauer, Jenny C. Taylor, Frank von Delft, Brian D. Marsden, Charlotte M. Deane

“…This method has had a prior real-world application in hit-to-lead screening, yielding a sub-micromolar merger from parent hits in a single round. …”
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Multi-view knowledge representation learning for personalized news recommendation by Chao Chang, Feiyi Tang, Peng Yang, Jingui Zhang, Jingxuan Huang, Junxian Li, Zhenjun Li

“…Extensive experiments on three real-world datasets demonstrate that our proposed framework outperforms state-of-the-art baselines in recommendation accuracy, validating its effectiveness.…”
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