Systematic Evaluation of Clinical Efficacy of Shiyiwei Shenqi (Ginseng and Astraglus, Eleven Ingredients) Preparation in Adjuvant Chemotherapy for Malignant Tumor by Bowei HUANG, Yuhui ZENG, Lisha LU, Huijuan GAN

“…Outcome indicators were: clinical efficacy (effective rate, stability rate), karnofsky performance scale, bone marrow suppression (white blood cells, hemoglobin), gastrointestinal reactions (nausea, vomiting), liver and renal function, etc.Results:A total of nine RCTs were included, including 633 patients, with 318 cases in the experimental group, 315 cases in the control group. …”
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Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study by Wei Ji, Wei Ji, Liping Sun, Liping Sun, Yue Huang, Yue Huang, Jie Bai, Jie Bai, Jijian Zheng, Jijian Zheng, Kan Zhang, Kan Zhang

“…The incidence of postoperative vomiting was also lower among children receiving oxycodone [14.1% (7/41) vs. 24.4% (10/41), p = 0.032].ConclusionOxycodone (0.2 mg kg−1) can provide effective analgesia and stable hemodynamics in children undergoing ERCP. …”
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De Novo Mutation of m.3243A>G together with m.16093T>C Associated with Atypical Clinical Features in a Pedigree with MIDD Syndrome by Zhixin Jiang, Yinan Zhang, Jingbin Yan, Fengwen Li, Xinqian Geng, Huijuan Lu, Xiaoer Wei, Yanmei Feng, Congrong Wang, Weiping Jia

“…The proband (F1957-II-1) and her son (F1957-III-1) both manifested diabetes with mild bilateral sensorineural hearing loss (SNHL) and abnormal brain MRI, and F1957-III-1 also complained of severe nausea and vomiting. Mitochondrial function evaluation in PBMCs revealed an increased level of ROS generation and decreased levels of ATP and mitochondrial membrane potential (ΔΨm) in the two m.3243A>G carriers. …”
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Clinical findings of acute necrotizing esophagitis complicated by diabetic ketoacidosis by Yuichiro Iwamoto, Tomohiko Kimura, Takashi Itoh, Shigehito Mori, Taku Sasaki, Mana Ohnishi, Haruka Takenouchi, Hideyuki Iwamoto, Junpei Sanada, Yoshiro Fushimi, Yukino Katakura, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto

“…Gastrointestinal symptoms were also significantly more pronounced in the ANE group, with vomiting occurring in 85.7% of patients compared to only 13.0% in the non-ANE group. …”
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Investigation of the optimal platinum-based regimen in the postoperative adjuvant chemotherapy setting for early-stage resected non-small lung cancer: a Bayesian network meta-analy... by Li Zhang, Wen-Feng Fang, Yi Lv, Lan-Lan Pang, Jia-Di Gan, Yi-Hua Huang, Jun Liao, Wael Abdullah-Sultan Ali

“…In terms of the safety of adjuvant chemotherapy, the incidence of haematological toxicities and nausea/vomiting was not significantly higher in the ‘cisplatin_vinorelbine’ arm than in other chemotherapy group.Conclusion This study summarised the adjuvant cytotoxicity chemotherapy regimens for patients with early-stage resected NSCLC. …”
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Application of pediatric massage combined with Traditional Chinese Medicine application in antipyretic treatment of children with exogenous fever (小儿推拿联合中药敷贴在外感发热患儿退热中的应用)... by TANG Xianlan (汤先兰), GAN Na (甘娜), HUANG Biqiu (黄碧秋)

“…No adverse reaction was reported in the treatment group; There were 3 cased of headache and 7 cases of nausea/vomiting reported in the control group. The antipyretic onset time and complete antipyretic time in the treatment group were shorter than those in the control group (P＜0. 01). …”
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A retrospective study of pembrolizumab combined with XELOX regimen in the treatment of advanced gastric cancer by FENG Huizhi, LIU Jingmei, BU Xiaoqian

“…There was no significant difference in the incidence of nausea and vomiting, diarrhea, leukopenia, rash, liver function damage between the two groups (P > 0.05). …”
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Emerging burden of post-cancer therapy complications on unplanned hospitalisation and costs among Australian cancer patients: a retrospective cohort study over 14 years by Rashidul Alam Mahumud, Md. Shahjalal, Padam Kanta Dahal, Md. Parvez Mosharaf, Sabuj Kanti Mistry, Kamrun Nahar Koly, Sujana Haque Chowdhury, Andre M. N. Renzaho, Jeff Gow, Khorshed Alam, Olivia Wawryk

“…A significant proportion of patients (71%) experienced multiple complications, with the most common being anemia (26%), sepsis (15%), nausea and vomiting (14%), and neutropenia (11%). Patients undergoing combined systemic and radiotherapy exhibited higher odds of post-therapy complications (OR = 8.24, 95%CI: 7.48 to 9.08) compared with those who only received systemic therapy. …”
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Intra-Arterial Chemotherapy with Doxorubicin and Cisplatin Is Effective for Advanced Hepatocellular Cell Carcinoma by Ming-Chun Ma, Yen-Yang Chen, Shau-Hsuan Li, Yu-Fan Cheng, Chih-Chi Wang, Tai-Jan Chiu, Sung-Nan Pei, Chien-Ting Liu, Tai-Lin Huang, Chen-Hua Huang, Yu-Li Su, Yen-Hao Chen, Sheng-Nan Lu, Kun-Ming Rau

“…Worsening of liver function, nausea, and vomiting were uncommon side effects. This study demonstrated clinical efficacy and tolerable side effects of repeated IACT with doxorubicin and cisplatin in advanced HCC. …”
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Application of care bundles based on the concept of enhanced recovery after surgery in perioperative nursing of patients undergoing laparoscopic cholecystectomy (基于加速康复外科理念的集束化干预在腹... by FANG Shuheng (房树恒), ZHU Hengmei (朱恒美), DONG Zhitao (董志涛), HE Dandan (贺丹丹)

“…The time to first postoperative exhaustion, time to off-bed activities and hospital stays in the observation group were shorter than those in the control group (P＜0. 05). The incidence of vomiting, incision infection, and bile leakage in the control group was significantly higher than that in the observation group, with a significant difference (P＜0. 05). …”
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Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms by Billy Ogwel, Vincent H. Mzazi, Alex O. Awuor, Caleb Okonji, Raphael O. Anyango, Caren Oreso, John B. Ochieng, Stephen Munga, Dilruba Nasrin, Kirkby D. Tickell, Patricia B. Pavlinac, Karen L. Kotloff, Richard Omore

“…The following variables were associated with LDD in decreasing order: pre-enrolment diarrhea days (55.1%), modified Vesikari score(18.2%), age group (10.7%), vomit days (8.8%), respiratory rate (6.5%), vomiting (6.4%), vomit frequency (6.2%), rotavirus vaccination (6.1%), skin pinch (2.4%) and stool frequency (2.4%). …”
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

“…Typhimurium, ST) is a food-borne pathogen that can be transmitted from animals to humans and causes symptoms such as diarrhea, fever, and vomiting. While antibiotics are commonly used to treat clinical infections, the increase in drug resistance has limited their effectiveness. …”
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Faecal microbiota transplantation for patients with diabetes type 1 and severe gastrointestinal neuropathy (FADIGAS): a randomised, double-blinded, placebo-controlled trialResearch... by Katrine Lundby Høyer, Simon Mark Dahl Baunwall, Ditte Smed Kornum, Mette Winther Klinge, Asbjørn Mohr Drewes, Knud Bonnet Yderstræde, Louise Bruun Thingholm, Martin Steen Mortensen, Susan Mikkelsen, Christian Erikstrup, Christian Lodberg Hvas, Klaus Krogh

“…Summary: Background: Diabetic gastroenteropathy is associated with nausea, vomiting, bloating, pain, constipation, and diarrhoea. …”
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Safety and efficacy of intraoperative radiation therapy using a low-energy X-ray source for resectable pancreatic cancer: an interim evaluation of an ongoing prospective phase II s... by Xingyun Chen, Shuo Li, Chuntao Gao, Wei Wang, Haorui Li, Yuxiao Liu, Rui Liu, Jihui Hao

“…Within 30 days after surgery, one patient experienced abdominal pain, another experienced vomiting, and one died because of abdominal infection and a grade C pancreatic fistula. …”
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Clinical Characteristics, Laboratory Parameters, and Molecular Epidemiology of Neuroinvasive Flavivirus Infections in a Hotspot Region of Eastern Croatia by Dario Sabadi, Kristian Bodulić, Vladimir Savić, Nika Vlahović Vlašić, Maja Bogdanić, Ljiljana Perić, Irena Tabain, Dubravka Lišnjić, Mario Duvnjak, Snježana Židovec-Lepej, Barbara Grubišić, Ilija Rubil, Ljubo Barbić, Luka Švitek, Vladimir Stevanović, Petra Smajić, Bernarda Berišić, Mihaela Zlosa, Ivana Rončević, Tatjana Vilibić-Čavlek

“…No significant differences in the frequency of clinical symptoms were observed between WNV and TBEV-infected patients (fever 93.7 vs. 100%; malaise 78.1 vs. 100%; headache 75.0 vs. 100%; nausea 50.0 vs. 63.6%; vomiting 34.4 vs. 54.6%). Comparative analysis of total and differential leukocyte blood count showed similar results. …”
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Effect of Bian-stone hot ironing-massage and Chinese herbal medicine penetration combined with auricular acupoint sticking and pressing on relief of incomplete intestinal obstructi... by ZHANG Lihua (张丽华), XUE Li (薛丽), HUANG Yanping (黄砚萍), WANG Guifang (王贵芳)

“…Results The time to relief of abdominal pain, abdominal distension, nausea and vomiting and difficult defecation in the treatment group was shorter than that in the control group (P＜0. 01). …”
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Meta Analysis of Effectiveness on Acupuncture Assisted Rehabilitation after Total Knee Arthroplasty by LI Naping, YANG Shaofeng, KUANG Gaoyan, ZENG Fan, TU Duxing, LU Min

“…Compared with the routine treatment, the meta-analyses indicated that: 1) The resting visual analogue scale (VAS-R) score after TKA in the acupuncture group was significantly decreased [postoperatively 1 d, <italic>MD</italic>=-0.65, 95%<italic>CI</italic> (-0.87, -0.42), <italic>P</italic>&lt;0.000 01; postoperatively 2 d, <italic>MD</italic>=-0.35, 95%<italic>CI</italic> (-0.50, -0.21), <italic>P</italic>&lt;0.000 01]. 2) The passive functional exercises visual analogue scale (VAS-P) score in the acupuncture group was significantly decreased after the surgery [postoperatively 1 d, <italic>MD</italic>=-1.01, 95%<italic>CI</italic> (-1.70, -0.33), <italic>P</italic>=0.004&lt;0.05; postoperatively 2 d, <italic>MD</italic>=-0.80, 95%<italic>CI</italic> (-1.43, -0.17), <italic>P</italic>=0.001&lt;0.05; postoperatively 3 d, <italic>MD</italic>=-0.90, 95%<italic>CI</italic> (-1.61, -0.18), <italic>P</italic>=0.01&lt;0.05; postoperatively 7 d, <italic>MD</italic>=-0.60, 95%<italic>CI</italic> (-0.98, -0.21), <italic>P</italic>=0.002&lt;0.05; postoperatively 14 d, <italic>MD</italic>=-0.63, 95%<italic>CI</italic> (-1.07, -0.19), <italic>P</italic>=0.005&lt;0.05]. 3) The range of motion of the acupuncture group was significantly improved [postoperatively 3 d, <italic>SMD</italic>=0.47, 95%<italic>CI</italic> (0.19, 0.75), <italic>P</italic>=0.001&lt;0.05; postoperatively 7 d, <italic>SMD</italic>=0.47, 95%<italic>CI</italic> (0.12, 0.83), <italic>P</italic>=0.009&lt;0.05; postoperatively 14 d, <italic>SMD</italic>=0.26, 95%<italic>CI</italic> (0.00, 0.53), <italic>P</italic>=0.05≤0.05]. 4) There was significantly better postoperative improvement in the joint function score of the acupuncture group [postoperatively 7 d, <italic>SMD</italic>=0.71, 95%<italic>CI</italic> (0.41, 1.01), <italic>P</italic>&lt;0.000 01; postoperatively 14 d, <italic>SMD</italic>=0.66, 95%<italic>CI</italic> (0.36, 0.96), <italic>P</italic>&lt;0.000 1; at the end of the study, <italic>SMD</italic>=0.69, 95%<italic>CI</italic> (0.21, 1.17), <italic>P</italic>=0.005&lt;0.05]. 5) The incidence of postoperative analgesic adverse reactions was lower in the acupuncture group [vomiting, <italic>OR</italic>=0.11, 95%<italic>CI</italic> (0.06, 0.24), <italic>P</italic>&lt;0.000 01; urinary retention, <italic>OR</italic>=0.26, 95%<italic>CI</italic> (0.11, 0.63), <italic>P</italic>=0.003&lt;0.05].ConclusionThe effectiveness of acupuncture-assisted TKA postoperative rehabilitation is better than that of routine treatment. …”
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Acute gastrointestinal and post-acute COVID-19 gastrointestinal syndrome assessment on the Gastrointestinal Symptom Rating Scale scoring system: A questionnaire-based survey by Sunita Singh, Niraj K. Srivastava, Rahul Yadav, Saurabh Paul, Shefali Gupta, Sankalp, Priyanshi Dixit

“…The four major GI symptoms analyzed in the study were vomiting, pain in the abdomen, diarrhea, and constipation. …”
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Pediatric bacterial meningitis in southern China: analysis of 838 cases by Lianfeng Chen, Wen-Lin Wu, Yuanyuan Gao, Xiaojing Li, Sida Yang, Huici Liang, Kelu Zheng, Yani Zhang, Haixia Zhu, Yang Tian, Bingwei Peng, Haisheng Lin, Xiuying Wang, Shuyao Ning, Yinyan Gan, Chi Hou, Yinting Liao, Huiling Sheng, Wen-Xiong Chen, Wen-Xiong Chen

“…Common symptoms included fever, seizure, lethargy, vomiting, anorexia, poor feeding, and irritability. …”
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Clostridioides difficile infection and recurrence in cancer patients (CIRCA): A multicentre, international study by Pedro Puerta-Alcalde, Jessica O'Keefe, Rachel Woolstencroft, Shipraa Kaul, Néstor López, Katie Cronin, Andrew Lim, Nicole Garcia-Pouton, Míriam Álvarez, Lynette Chee, Mateu Espasa, Ignacio Grafia, Maria Suárez-Lledó, Olivia Smibert, Carolina Garcia-Vidal, Monica A. Slavin, Michelle K. Yong, Alex Soriano, Leon J. Worth

“…Independent risk factors for CDI recurrence were female sex (OR 2.26, 95% CI 1.13-4.52), age >75 years (OR 2.69, 95% CI 1.30-5.59), dialysis (OR 5.15, 95% CI 1.45-18.27), vomiting at presentation (OR 0.06, 95% CI 0.01-0.55), colonic wall thickening in the CT abdomen (OR 2.42, 95% CI 1.06-5.49) and vancomycin therapy (OR 4.60, 95% CI 1.34-15.84). …”
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