Electroacupuncture attenuates ferroptosis by promoting Nrf2 nuclear translocation and activating Nrf2/SLC7A11/GPX4 pathway in ischemic stroke by Xi-chen Yang, Ya-ju Jin, Rong Ning, Qiu-yue Mao, Peng-yue Zhang, Li Zhou, Cheng-cai Zhang, Yi-chen Peng, Na Chen

“…The behavioral function was evaluated by Neurologic severity score (NSS), Garcia score, Foot-fault Test, and Rotarod Test. The infarct volume was detected by TTC staining, and the neuronal damage was observed by Nissl staining. …”
Get full text

Diagnostic markers of severe diabetic macular edema in patients with type 2 diabetes by S.A. Suk, S.Yu. Mogilevskyy

“…According to OCT data, area thickness was 357.62 ± 1.80 μm, min in fovea — 360.04 ± 2.40 μm, central sector — 403.52 ± 2.10 μm, volume — 10.67 ± 0.10 mm3, NFL + GCL + IPL average — 139.26 ± 0.40 μm, NFL + GCL + IPL min — 124.38 ± 0.30 μm, GCL — 98.94 ± 0.30 μm, NFL — 42.42 ± 0.20 μm. …”
Get full text

Longitudinal Outcomes of Patients with Aortic Stenosis Stratified by Sex: An Asian Perspective by Joy Y. S. Ong, Aloysius S. T. Leow, Chun Yi Ng, Poay Huan Loh, Swee Chye Quek, William K. F. Kong, Tiong Cheng Yeo, Ching Hui Sia, Kian Keong Poh

“…Echocardiographically, females had a smaller left ventricular outflow tract diameter (LVOTd) (<i>p</i> < 0.001), LV mass (<i>p</i> < 0.001), and left ventricle end diastolic volume (LVEDV) (<i>p</i> < 0.001). Conversely, the left atrial (LA) area (<i>p</i> < 0.001) and volume index (LAVI) (<i>p</i> < 0.001) were larger in females. …”
Get full text

Automated Synthesis and Initial Evaluation of (4′-Amino-5′,8′-difluoro-1′H-spiro[piperidine-4,2′-quinazolin]-1-yl)(4-[18F]fluorophenyl)methanone for PET/MR Imaging of Inducible Nit... by Skye Hsin-Hsien Yeh, Wen-Sheng Huang, Chuang-Hsin Chiu, Chuan-Lin Chen, Hui-Ting Chen, Dae Yoon Chi, Zhengxing Ge, Tsung-Hsun Yu, Pao-Yeh Wang, Yu-Yeh Kuo, Chun-Tse Hung, Geng-Ying Li, Chi-Wei Chang

“…Standard uptake value (SUV), total volume of distribution (Vt), and area under the curve (AUC) based on the [18F]FBAT PET signals were determined. …”
Get full text

Mature Tiankengs are biodiversity hotspots of soil microorganisms in the karst region by Junbo Yang, Xiaohui Wang, Keyi Wang, Danjuan Zeng, Ling Mo, Shuai Li, Baozhu Fang, Bhagwan Rekadwad, Wenjun Li, Gaozhong Pu

“…Since the soil microbial hotspot was defined as soil with small volume and high process rates, we suggest that the theory of soil microbial hotspot may be applied on landscape scales. …”
Get full text

Enzymic Activity, Metabolites, and Hematological Responses Changes of Clinical Healthy High-Risk Beef Calves During Their First 56-Days from Arrival by Octavio Carrillo-Muro, Pedro Hernández-Briano, Paola Isaira Correa-Aguado, Alejandro Rivera-Villegas, Oliver Yaotzin Sánchez-Barbosa, Rosalba Lazalde-Cruz, Alberto Barreras, Alejandro Plascencia, Daniel Rodríguez-Cordero

“…The following parameters were determined: total white blood cells (WBC): lymphocytes (LYM), lymphocytes % (LYM%), monocytes (MON), monocytes % (MON%), granulocytes (GRA), granulocytes % (GRA%), platelets (PLT), and mean platelet volume (MPV); red blood cells (RBC): red blood cell distribution width test % (RDW%), hematocrit (HCT), and mean corpuscular volume (MCV); hemoglobin (HGB): mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). …”
Get full text

Effect of ERAS-based sputum drainage nursing model on improving postoperative pulmonary function recovery in elderly patients with aneurysmal subarachnoid hemorrhage (基于ERAS模式的排痰护理... by CAO Shuonan (曹硕楠), YUAN Qiaoling (袁巧玲), LIU Ranran (刘冉冉)

“…Results At 5th day after intervention, the daily expectoration volume ［(40. 51±9. 25) mL vs. (22. 52±4. 25) mL, P＜0. 01］ and blood oxygen saturation［(94. 52±4. 57)% vs…”
Get full text

Association of body composition with neuroimaging biomarkers and cognitive function; a population-based study of 70-year-oldsResearch in context by Jessica Samuelsson, Anna Marseglia, Ola Wallengren, Olof Lindberg, Caroline Dartora, Nira Cedres, Sara Shams, Silke Kern, Anna Zettergren, Eric Westman, Ingmar Skoog

“…Methods: Dual-energy X-ray absorptiometry body composition measures in relation to neuroimaging measures of cortical thickness, hippocampal volume, small vessel disease, predicted brain age, and cognitive performance were explored in a cross-sectional study of 674 dementia-free 70-year-olds from the Swedish Gothenburg H70 Birth Cohort study. …”
Get full text

Optimization of salinity range for rearing glass eel Anguilla bicolor bicolor by Ade Yulita Hesti Lukas, Daniel Djokosetiyanto, Tatag Budiardi, Agus Oman Sudrajat, Ridwan Affandi

“…The experiment was conducted in an aquarium of 60×30×30 cm with a volume of 30 Liters and at a stocking density of 2 g/L for 14 days. …”
Get full text

Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis. by Javier Lozano-Gerona, Aida Oliván-Viguera, Pablo Delgado-Wicke, Vikrant Singh, Brandon M Brown, Elena Tapia-Casellas, Esther Pueyo, Marta Sofía Valero, Ángel-Luis Garcia-Otín, Pilar Giraldo, Edgar Abarca-Lachen, Joaquín C Surra, Jesús Osada, Kirk L Hamilton, Siba P Raychaudhuri, Miguel Marigil, Ángeles Juarranz, Heike Wulff, Hiroto Miura, Yolanda Gilaberte, Ralf Köhler

“…Here, we explored the consequences of genetically encoded induction of the cell volume-regulating Ca2+-activated KCa3.1 channel (Kcnn4) for murine epidermal homeostasis. …”
Get full text

Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter by Su Jeong Song, Soo-Wang Hyun, Tae Gu Lee, Bongkyun Park, Kyuhyung Jo, Ik Soo Lee, Chan-Sik Kim

“…Topical administration of LPE attenuated the PM-induced decrease in tear volume and reduced corneal epithelial irregularity and damage. …”
Get full text

Research hotspots and frontiers in metakaolin-based geopolymer studies: a bibliometric analysis by Peng Wang, Mingquan Ma, Fei Wang

“…The findings reveal a pronounced growth trend in the annual publication volume of metakaolin-based geopolymers, particularly entering a phase of accelerated development after 2019. …”
Get full text

Toyin Falola and Akintunde Akinyemi (Eds). Encyclopedia of the Yoruba. Bloomington and Indianapolis: Indiana University Press, 2016. 371pp. by Ibrahim A. Odugbemi

“… Encyclopedia of the Yoruba is a single-volume encyclopedia that is comprised of 285 entries of short essays written by 188 authors who are predominantly scholars and academic researchers from Africa, Europe and North America. …”
Get full text

Developability considerations for bispecific and multispecific antibodies by Alaa Amash, Gesa Volkers, Patrick Farber, Daniel Griffin, K. Shawn Davison, Allison Goodman, Raffi Tonikian, Aaron Yamniuk, Bryan Barnhart, Tim Jacobs

“…Important considerations when assessing the developability of bsAbs/msAbs include their molecular format, likelihood for immunogenicity, specificity, stability, and potential for high-volume production. Here, we summarize the critical aspects of developability assessment, and provide guidance on how to develop a comprehensive plan tailored to a given bsAb/msAb.…”
Get full text

Novel Modifications and Delivery Modes of Cyclic Dinucleotides for STING Activation in Cancer Treatment by Lu Y, Li Z, Zhu X, Zeng Q, Liu S, Guan W

Get full text