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141
EFFICIENT RETINAL IMAGE SEGMENTATION BY U-NET FOR AGE-RELATED MACULAR DEGENERATION DIAGNOSIS
Published 2024-12-01“…Age-related Macular Degeneration (AMD) is a prominent factor contributing to visual impairment in older people, characterized by deterioration of the macula, the center part of the retina. …”
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142
Inherited glycosylphosphatidylinositol deficiency disorders: a new group of inherited metabolic disorders
Published 2024-12-01“…Patients present a variety of symptoms including developmental delay with intellectual disability, abnormalities of the central nervous, skeletal, circulatory, gastrointestinal, and urinary systems, facial dysmorphia as well as hearing and visual impairment. Elevated alkaline phosphatase is a characteristic biochemical feature. …”
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143
A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis
Published 2018-01-01“…Early diagnosis and aggressive antiviral therapy are important in cases of herpes zoster ophthalmicus to prevent the possible development of MS as well as visual impairment as sequela.…”
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144
The Role of SGLT2 Inhibitor on the Treatment of Diabetic Retinopathy
Published 2020-01-01“…DR has an early onset and is not easy to detect. When visual impairment occurs, the optimal period for therapy is often missed. …”
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145
CLN6‐related continuum phenotype caused by aberrant splicing
Published 2025-02-01“…Abstract Neuronal ceroid lipofuscinoses (NCLs) are genetically heterogeneous neurodegenerative disorders, characterized by progressive cognitive and motor decline, epilepsy, visual impairment, and shortened life‐expectancy. CLN6‐related NCLs include both late‐infantile and adult myoclonic form. …”
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146
The Successful Use of Infliximab in a Relapsing Case of Susac’s Syndrome
Published 2020-01-01“…He has the sequelae of bilateral sensorineural hearing loss but no visual impairment or cognitive deficits on follow-up with neuropsychometric testing. …”
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147
Non-Viral Delivery Systems to Transport Nucleic Acids for Inherited Retinal Disorders
Published 2025-01-01“…Inherited retinal disorders (IRDs) represent a group of challenging genetic conditions that often lead to severe visual impairment or blindness. The complexity of these disorders, arising from their diverse genetic causes and the unique structural and functional aspects of retinal cells, has made developing effective treatments particularly challenging. …”
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148
Cholinergic Potentiation of Restoration of Visual Function after Optic Nerve Damage in Rats
Published 2017-01-01“…Enhancing cortical plasticity and brain connectivity may improve residual vision following a visual impairment. Since acetylcholine plays an important role in attention and neuronal plasticity, we explored whether potentiation of the cholinergic transmission has an effect on the visual function restoration. …”
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149
Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy
Published 2018-01-01“…Inherited retinal dystrophies (IRDs) are a leading cause of visual impairment in the developing world. These conditions present an irreversible dysfunction or loss of neural retinal cells, which significantly impacts quality of life. …”
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150
Prevalence of amblyopia among adult population and their various impacts on life: An experience over a period of eight months
Published 2024-12-01“…Conclusion: Awareness of amblyopia among the parents is essential for early detection and treatment of the disease, which will, in turn, reduce the burden of childhood visual impairment.…”
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151
Retina Modeling by Artificial Neural Networks
Published 2024-03-01“…The model, as mentioned above, has potential applications in the development of artificial retinas, serving as a hardware implementation to restore some visual capabilities in individuals with visual impairments.…”
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152
Neuroprotection as a Therapeutic Target for Diabetic Retinopathy
Published 2016-01-01“…DR has long been regarded as a vascular disorder, although neuronal death and visual impairment appear before vascular lesions, suggesting an important role played by neurodegeneration in DR and the appropriateness of neuroprotective strategies. …”
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153
Limbal Stem Cell Transplantation: Clinical Results, Limits, and Perspectives
Published 2018-01-01“…In these patients, the conjunctivalization of the cornea is associated with visual impairment and cornea transplantation has poor prognosis for recurrence of the conjunctivalization. …”
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154
Detection of Diabetic Retinopathy Using a Multi-Decision Inception-ResNet-Blended Hybrid Model
Published 2025-01-01“…Diabetic retinopathy (DR) is a severe complication of diabetes that affects the retinal structures and can lead to significant visual impairment or even blindness. Early diagnosis is crucial for reducing and preventing the progression of this condition. …”
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155
Prediction of OCT contours of short-term response to anti-VEGF treatment for diabetic macular edema using generative adversarial networks
Published 2025-04-01“…However, a significant portion of patients remain insensitive to anti-VEGF, resulting in sustained visual impairment. Therefore, it's imperative to predict prognosis and formulate personalized therapeutic regimens. …”
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156
A Study and Development of Workplace Facilities and Working Environment to Increase the Work Efficiency of Persons with Disabilities: A Case Study of Major Retail and Wholesale Com...
Published 2018-01-01“…It focuses on the environment and facilities needed by people with three types of disabilities, visual impairment, hearing impairment, and wheelchair users. …”
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157
Single-cell sequencing in diabetic retinopathy: progress and prospects
Published 2025-01-01“…Abstract Diabetic retinopathy is a major ocular complication of diabetes, characterized by progressive retinal microvascular damage and significant visual impairment in working-age adults. Traditional bulk RNA sequencing offers overall gene expression profiles but does not account for cellular heterogeneity. …”
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158
Web Accessibility Analysis of Massive Open Online Courses in Mathematical Disciplines
Published 2019-11-01“…By automatic testing using Web Accessibility Checker, the accessibility of the functional and informational content of the MOOCs was evaluated. 73% of MOOCs were found to conform to the syllabus subjects “Probability Theory and Mathematical Statistics”, “Discrete Mathematics” and “Algebra and Geometry”; 8 basic disciplines of higher mathematics education are not covered by online education; 96,4% of the courses have accessibility limitations, especially for people with visual impairment. Accessibility problems are related to shortcomings of the platforms and MOOC developers’ errors. …”
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159
Mechanism of Inflammation in Age-Related Macular Degeneration
Published 2012-01-01“…Age-related macular degeneration (AMD) is a multifactorial disease that represents the most common cause of irreversible visual impairment among people over the age of 50 in Europe, the United States, and Australia, accounting for up to 50% of all cases of central blindness. …”
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160
Prevalence of Non-Communicable Diseases Among Elderly in India: A Scoping Review
Published 2025-02-01“…Significant gender disparities existed in hypertension, depression, diabetes, and visual impairments. Conclusion: This review highlights the significant NCD burden among elderly Indians, particularly hypertension and diabetes, underscoring the need for targeted health interventions. …”
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