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661
Risk of Cirrhosis in Patients with Non-alcoholic Fatty Liver Disease and Previous Viral Hepatitis B
Published 2020-09-01“…To confirm previous and occult hepatitis B virus (HBV) infection, blood of all participants was examined for anti-HBc (IgG) and HBV DNA. …”
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662
Correlation of the cycle threshold value of SARS-CoV-2 by RT-PCR with biomarker levels in the prognosis of patients hospitalized with COVID-19
Published 2025-01-01“…Background and Objective: The COVID-19 disease caused by SARS-CoV-2 was declared as pandemic by WHO soon after its emergence in 2019. This virus was known to cause serious clinical symptoms and severe illness. …”
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663
Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81
Published 2023-11-01“…They display anticancer and antiviral effects, reducing the entry of hepatitis C virus (HCV) into hepatocarcinoma cells. The large extracellular loop (LEL) of the tetraspanin protein CD81 represents a molecular target for both Hz-A and Hz-B. …”
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664
Diagnosis and presenting features of autoimmune hepatitis at a central referral hospital in South Africa
Published 2024-04-01“…Similarly, few studies have focused on the relationship between AIH and Human-Immunodeficiency Virus (HIV) infection. Aim We aim to describe the presenting features of AIH from a single referral centre in a Sub-Sahara African setting. …”
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665
LINC02282 promotes DNA methylation of TRIM6 by recruiting DNMTs to inhibit the progression of Parkinson's disease
Published 2025-03-01“…In addition, LINC02282 overexpression using an adeno-associated virus reduced neuronal damage in PD mice. LINC02282 was mainly localized in the nucleus, and LINC02282 promoted the methylation of the tripartite motif-containing protein 6 (TRIM6) promoter to inhibit TRIM6 expression. …”
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666
Neglected tropical diseases in Yemen: a systematic review of epidemiology and public health challenges
Published 2025-02-01“…Dengue virus, hepatitis B and C viruses were the most prominent viral pathogens, while bacterial NTDs were primarily caused by Escherichia coli, cholera, and Salmonella. …”
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667
Study of COVID-19 cases with real data analysis
Published 2025-02-01“…In this work, patients of corona virus disease 2019, known as COVID-19, have been studied in Pakistan and its neighboring countries Iran, India and Afghanistan through the mathematical model in the form of coupled system of five ordinary differential equations. …”
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668
Pregnancy-Specific Concerns and Psychological Impact of COVID-19 on Antenatal Women
Published 2022-08-01“…Pregnant women, being a vulnerable group, are grossly affected by these changing environmental scenarios. The spread of Corona Virus infection itself and the subsequent nation-wide lockdown in India, just like many other countries, has caused a serious impact on antenatal patients. …”
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669
Nanomechanical characterization of soft nanomaterial using atomic force microscopy
Published 2025-04-01“…Atomic force microscopy (AFM) is a promising method for generating high-spatial-resolution images, providing insightful perspectives on the nanomechanical attributes of soft matter, including cells, bacteria, viruses, proteins, and nanoparticles. AFM is widely used in biological and pharmaceutical sciences because it can scrutinize mechanical properties under physiological conditions. …”
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670
Acute hepatitis of non-specified etiology
Published 2011-02-01“…To estimate pathogenic and diagnostic value of detection of hepatotropic viruses components (DNA, RNA, antigens) and antiviral immune response at acute hepatitis of non-specified etiology by the methods of enzyme-linked immunoassay (EIA), polymerase chain reaction (PCR) and Т-cellular lymphocytes proliferation in response to HCV antigens stimulation.Methods. …”
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671
Nebulised 3% hypertonic saline versus 0.9% saline for treating patients hospitalised with acute bronchiolitis: protocol for a randomised, double-blind, multicentre trial
Published 2023-11-01“…It is most commonly caused by respiratory syncytial virus. Being a common reason for hospitalisation, it affects 13–17% of all hospitalised children younger than 2 years. …”
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672
Examining Effects of the COVID-19 National Lockdown on Ambient Air Quality Across Urban India
Published 2024-12-01“…Thus, India has enforced nation-wide lockdown from 25th March to lower the spread of this contagious virus and associated illness. This study aims to quantify the changes in pollution levels as well as meteorology during the 6-weeks COVID-19 lockdown over 17 cities of India for 5 major criteria pollutants using publicly available air quality data. …”
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673
Urine amino acid and gamma aminobutyric acid level in COVID 19 patients
Published 2025-02-01“…Conclusion: It has been thought that the height of GABA may be due to bacteria producing GABA as a result of the change in microbiota due to lactic acidosis, as well as that the virus may directly affect the brain and cause an increase in GABA. …”
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674
SARS-Cov-2 Incidence Monitoring and Statistical Estimation of the Basic and Time-Varying Reproduction Number at the Early Onset of the Pandemic in 45 Sub-Saharan African Countries.
Published 2024“…The region’s basic reproduction number (R0) was 1.89 (95% CI: 1.767 to 2.026) using the growth model and 1.513 (95% CI: 1.491 to 1.535) with the maximum likelihood method, indicating that, on average, infected individuals transmitted the virus to less than two secondary persons. Several countries, including Sudan (R0: 2.03), Ghana (R0: 1.87), and Somalia (R0: 1.85), exhibited high transmission rates. …”
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675
The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections
Published 2021“…PCR remains the standard benchmark for initial diagnosis of COVID- 19 infection, while advances in immunological profiling are guiding clinical treatment. The SARSCov- 2 virus has undergone multiple mutations since its emergence in 2019, resulting in changes in virulence that have impacted on disease severity globally. …”
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676
Tecovirimat in the management of poxviruses: a narrative review of available evidence
Published 2025-02-01“…Early intervention slowed disease progression in vulnerable populations, such as people living with HIV (PLWHIV). Recovery times, virus eradication, and symptom relief varied among studies, but wider access and usage showed better clinical symptoms and tolerable side effects. …”
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677
Indoor and Outdoor Exposure to PM2.5 during COVID-19 Lockdown in Suburban Malaysia
Published 2020-11-01“…Abstract During the COVID-19 pandemic, key policies aimed at reducing exposure to the virus from social distancing, restrictions on travel through to strongly enforced lockdowns. …”
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678
Results of the ORION open comparative randomized trial: evaluation of efficacy of the Russian drugs Altevir and Phosphogliv in combined treatment of chronic hepatitis C
Published 2012-11-01“…The patient of the group B received no phosphogliv treatment, they received only standard AVT according to revealed virus genotype.Results. Intravenous injection of phosphogliv, prior to beginning of standard AVT, resulted in essential decrease of serum transaminase activity in group A, that was statistically significantly different from initial level. …”
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679
Complete genome sequencing and probiotic characterization of promising lactic acid bacterial strains isolated from dairy products in Egyptian markets
Published 2025-02-01“…The antibiotic sensitivity test was performed later to the antimicrobial assessment against widespread both negative and positive gram-stained bacteria infecting humans, along with the antiviral evaluation against (SARS-CoV-2), the virus that has disturbed the world recently. Results Out of nineteen investigated isolates, five potential probiotic isolates were examined for probiotic characteristics. …”
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680
Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters
Published 2025-02-01“…As a subunit intranasal COVID-19 vaccine reduced nasopharyngeal virus more than did an intramuscular (IM) vaccine, we hypothesized that this vaccine might reduce onward transmission to others.MethodsWe vaccinated hamsters with either the IM-administrated licensed mRNA vaccine twice or one dose of mRNA IM followed by adjuvanted subunit intranasal vaccine. 24 hours after SARS-CoV-2 challenge, these animals were housed with naïve recipients in a contactless chamber that allows airborne transmission.ResultsOnward airborne transmission was profoundly blocked: the donor and recipients of the intranasal vaccine-boosted group had lower oral and lung viral loads (VL), which correlated with mucosal ACE2 inhibition activity. …”
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