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5241
Pharmacological insights and therapeutic advances of mangiferin against various pathological conditions in liver diseases
Published 2025-03-01“…Currently, liver diseases have become a serious global health issue, and this situation occurs due to the exposure of the liver to different agents, such as chemicals, alcohol, viruses, and autoimmune diseases. Mangiferin is a natural bioactive xanthone C-glycoside compound and a potent antioxidant that is widely found in medicinal plants such as the leaves of Mangifera indica L. …”
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5242
Molecular Characterization and Evolution Analysis of Two Forms of TLR5 and TLR13 Genes Base on Larimichthys crocea Genome Data
Published 2020-01-01“…TLR13 is a TLR that localizes to endosomes and recognizes nucleic acids released by internal microorganisms, including viruses, bacteria, and fungi. Here, the full-length coding sequence (CDS), protein structure, and immune response and subcellular localization of TLR5 (TLR5S) and TLR13 were characterized in large yellow croaker (Larimichthys crocea). …”
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5243
Novel adaptive immune systems in pristine Antarctic soils
Published 2025-01-01“…Although several studies have investigated the phylogenetic repertoire of bacteria and viruses in these poly-extreme environments with freezing temperatures, high ultra violet irradiation levels, low moisture availability and hyper-oligotrophy, the evolutionary mechanisms governing microbial immunity remain poorly understood. …”
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5244
Characterization of acute respiratory infections behavior. Cienfuegos Province. First quarter 2020
Published 2020-10-01“…<br /><strong>Results:</strong> the characterizing essentialities were: its highest incidence in children under five years of age and adults 60 years and over; the leading cause of death was from community-acquired pneumonia; the identified circulating viruses were respiratory syncytial, parainfluenza, unsubtyped influenza A, and coronavirus. …”
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5245
Antibacterial Activity of Rationally Designed Antimicrobial Peptides
Published 2020-01-01“…Antimicrobial Peptides (AMPs) are components of the first line of defense for prokaryotes and eukaryotes and have a wide range of activities against Gram-negative and Gram-positive bacteria, fungi, cancer cells, and protozoa, as well as viruses. In this study, peptides which were initially identified for their HIV inhibitory activity were further screened for antibacterial activity through determination of their kinetics as well as their cytotoxicity. …”
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5246
A rapid visual detection method for porcine teschovirus through reverse transcription recombinase-aided amplification coupled with lateral flow dipstick
Published 2024-12-01“…Meanwhile, the assay established in this study showed no interaction with other associated diarrhea viruses, and has high specificity to PTV, with a minimal detection limit of 10 copies/μL and good repeatability. 128 clinical samples suspected of having a PTV infection were tested by RT-PCR and RT-RAA-LFD, respectively. …”
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5247
Real-World Effectiveness of Portable Air Cleaners in Reducing Home Particulate Matter Concentrations
Published 2023-11-01“…Abstract Portable air cleaners (PACs) equipped with HEPA filters are gaining attention as cost-effective means of decreasing indoor particulate matter (PM) air pollutants and airborne viruses. However, the performance of PACs in naturalistic settings and spaces beyond the room containing the PAC is not well characterized. …”
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5248
NRF2 Antioxidant Response and Interferon‐Stimulated Genes Are Differentially Expressed in SARS‐CoV‐2‐Positive Young Subjects
Published 2025-01-01“…ABSTRACT Background Several respiratory viruses, including Severe Acute Respiratory Syndrome‐Coronavirus‐2 (SARS‐CoV‐2), suppress nuclear factor‐E2‐related factor‐2 (NRF2) antioxidant response, generating oxidative stress conditions to its advantage. …”
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5249
Fungi in the Gut Microbiota: Interactions, Homeostasis, and Host Physiology
Published 2025-01-01“…The mammalian gastrointestinal tract is a stage for dynamic inter-kingdom interactions among bacteria, fungi, viruses, and protozoa, which collectively shape the gut micro-ecology and influence host physiology. …”
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5250
Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings
Published 2025-01-01“…We explore the mechanism of action of AMPs against bacteria, viruses, fungi and parasites. While these peptides hold significant promise, their application in mainstream drug development is hindered by challenges such as low bioavailability and potential toxicity. …”
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5251
Microbial biopesticides: A one health perspective on benefits and risks
Published 2025-06-01“…Microbial biopesticides, derived from bacteria, viruses, fungi, protozoa, or nematodes, offer potentially significant benefits for promoting One Health and contributing to several United Nations Sustainable Development Goals (SDGs). …”
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5252
Simple and Fail-safe Method to Transform Miniprep Escherichia coli Strain K12 Plasmid DNA Into Viable Agrobacterium tumefaciens EHA105 Cells for Plant Genetic Transformation
Published 2025-01-01“…Conventionally, plant genetic transformation has relied on time-consuming, costly, and technically demanding procedures, such as electroporation and chimeric viruses or biolistic methods, which usually yield variable transformation efficiencies. …”
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5253
Conducting polymer-based electrochemical sensors: Progress, challenges, and future perspectives
Published 2025-08-01“…Conducting polymers and their nanocomposites-based electrochemical sensors have demonstrated exceptional capabilities towards detecting various biomolecules, heavy metals, pesticides, and viruses like SARS-COV-2. Incorporation of redox mediators, use of conducting hydrogels, and molecular imprinting are promising strategies for better performance of the derived sensor. …”
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5254
Plant Mediated Green Synthesis and Antiviral Activity of Gold and Copper Nanoparticles using Malva parviflora L. Leaf Extract
Published 2024-06-01“…Although CuNPs have more cytotoxicity than AuNPs, they are more effective at killing viruses. Additionally, ethanolic extract showed significant antiviral activity at non-cytotoxic concentrations.…”
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5255
Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features
Published 2025-01-01“…However, in the detection of CMV/EBV viruses, there was no significant difference between the detection rate of mNGS and that of viral DNA quantification (p = 1.000 and 0.152). mNGS analysis revealed Prevotella, Streptococcus, Veillonella, Rothia, and Capnocytophaga as the most prevalent genera in the LRT of lung cancer patients. …”
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5256
A scoping review on bio-aerosols in healthcare and the dental environment.
Published 2017-01-01“…Fifty-five bacterial species, 45 fungi genera and ten viruses were identified in a hospital setting and 16 bacterial and 23 fungal species in the dental environment. …”
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5257
GENOME POLITICS: STRATEGY AND TACTICS
Published 1999-01-01“…This is clearly seen when the comparison between the information content (the gene number) and the life cycle of small genomes (plasmids, viruses, singlecellular prokaryotic organisms) is made: large space is occupied by information on replication enzymes and the sequence of replication origin. …”
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5258
Temperate phage-antibiotic synergy is widespread—extending to Pseudomonas—but varies by phage, host strain, and antibiotic pairing
Published 2025-02-01“…ABSTRACT Bacteriophages (phages) are bacterial-specific viruses that can be used alone or with antibiotics to reduce bacterial load. …”
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5259
Povidone-iodine in ophthalmological practice
Published 2018-07-01“…Antiseptic drugs, in particular different concentrations of povidone-iodine solution, have bactericidal activity with a wide spectrum of action (against bacteria, fungi, viruses, protozoa), lack of resistance to microorganisms, safety and good tolerability in local applications, and economic accessibility. …”
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5260
Enhancers and genome conformation provide complex transcriptional control of a herpesviral gene
Published 2024-11-01“…Abstract Complex transcriptional control is a conserved feature of both eukaryotes and the viruses that infect them. Despite viral genomes being smaller and more gene dense than their hosts, we generally lack a sense of scope for the features governing the transcriptional output of individual viral genes. …”
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