Fabry cardiomyopathy: Gb3‐induced auto‐reactive panmyocarditis requiring heart transplantation by Andrea Frustaci, Maurizio Scarpa, Rosalia Maria da Riol, Chiara Agrati, Nicoletta Finato, Romina Verardo, Claudia Grande, Cristina Chimenti, Concetta Di Nora, Matteo Antonio Russo, Ugolini Livi

“…Examining the explanted heart from a 57‐year‐old man with FD cardiomyopathy (CM) on 3‐year ERT presenting incoming ventricular fibrillation, we documented a severe virus‐negative myocarditis extended to cardiomyocytes, intramural coronary vessels, conduction tissue, and subepicardial ganglia. …”
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Cytotoxic Function and Cytokine Production of Natural Killer Cells and Natural Killer T-Like Cells in Systemic Lupus Erythematosis Regulation with Interleukin-15 by Syh-Jae Lin, Ming-Ling Kuo, Hsiu-Shan Hsiao, Pei-Tzu Lee, Wen-I Lee, Ji-Yih Chen, Jing-Long Huang

“…Natural killer cells and NKT-like cells are the first line immune defense against tumor and virus infection. Deficient NK and NKT-like cell effector function may contribute to increased susceptibility to infection in SLE patients. …”
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Solid medical waste management practices and awareness in COVID-19 screening stations by S.E. Alzghoul, O.A. Smadi, T. Almomani, M.B. Alzghoul, O.M. Al-Bataineh

“…Furthermore, the results of the third module revealed that the private sector fails to successfully execute national and international procedures, with the most significant negative responses among other categories.CONCLUSION: It was concluded that Jordan's solid waste collection and disposal methods were effectively implemented, which might aid in the virus eradication. Even though most Jordanian screening stations have effectively implemented knowledge and awareness regarding solid Coronavirus disease 2019 wastes management practices, there is a need to undertake periodic training and continuous monitoring with a specific focus on the appropriate administrative and collecting processes for both technicians, and private sector stations.…”
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Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases by Marilena Durazzo, Arianna Ferro, Victor Manuel Navarro-Tableros, Andrea Gaido, Paolo Fornengo, Fiorella Altruda, Renato Romagnoli, Søren K. Moestrup, Pier Luigi Calvo, Sharmila Fagoonee

“…Etiology-specific treatments, such as those for hepatitis B and C viruses, are already in clinical use, and efforts to develop new, targeted therapies for other chronic hepatobiliary diseases are ongoing. …”
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Lopinavir and Ritonavir have High Affinity Toward the SARS-CoV-2 S-protein Receptor-binding Domain Sequenced in Brazil by Aline Diogo Marinho, Helyson Lucas Bezerra Braz, João Alison de Moraes Silveira, Danilo Galvão Rocha, Roberta Jeane Bezerra Jorge, Geanne Matos de Andrade

“…Understanding the structural and functional interactions between the virus and host cells is critical for developing therapeutic strategies. …”
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Assessment of the quality of life in metastatic colorectal cancer patients with KRAS gene mutant: a case-control study by Fahmideh Bagrezaei, Bahram Pourghassem Gargari, Reza Eghdam Zamiri, Abdolrasoul Safaiyan, Mohammad Alizadeh

“…Abstract Background The mutation of the KRAS (Kirsten rat sarcoma virus) gene is a prevalent genetic alteration in metastatic colorectal cancer (mCRC). …”
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A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment by Ali Hussain Ansari, Saqib Hussain Ansari, Mubarak Jabeen Salman, Muhammad Usman Hussain Ansari, Rawshan Jabeen

“…These largely include hepatitis C, hepatitis B, and the Human immunodeficiency virus (HIV). TTIs impact the quality of life of these patients and their overall survival. …”
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Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression. by Julia Michalow, Magdalene K Walters, Olanrewaju Edun, Max Wybrant, Bethan Davies, Tendesayi Kufa, Thabitha Mathega, Sungai T Chabata, Frances M Cowan, Anne Cori, Marie-Claude Boily, Jeffrey W Imai-Eaton

“…In 2015, estimated primary aetiologies for vaginal discharge were candidiasis (69.4% [95% confidence interval (CI): 44.3% to 86.6%], n = 50), bacterial vaginosis (50.0% [95% CI: 32.3% to 67.8%], n = 39), chlamydia (16.2% [95% CI: 8.6% to 28.5%], n = 50), and trichomoniasis (12.9% [95% CI: 7.7% to 20.7%], n = 80); for urethral discharge were gonorrhoea (77.1% [95% CI: 68.1% to 84.1%], n = 68) and chlamydia (21.9% [95% CI: 15.4% to 30.3%], n = 48); and for genital ulcer were herpes simplex virus type 2 (HSV-2) (48.3% [95% CI: 32.9% to 64.1%], n = 47) and syphilis (9.3% [95% CI: 6.4% to 13.4%], n = 117). …”
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Cytomegalovirus infection in an immunocompetent host presenting as haemophagocytic lymphohistiocytosis by Inês Matias-Lopes, Henrique Atalaia Barbacena, Margarida Guiomar, Raquel Soares, Catarina Barão, Ana Rita Ferreira, Federica Parlato, Patrícia Howell-Monteiro

“…Cytomegalovirus (CMV) is a human herpes virus with a worldwide seroprevalence of 60-100%, mainly known to cause severe life-threatening disease in immunocompromised patients. …”
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Drug-Drug Interactions Between HIV Antivirals and Concomitant Drugs in HIV Patients: What We Know and What We Need to Know by Emanuela De Bellis, Danilo Donnarumma, Adele Zarrella, Salvatore Maria Mazzeo, Annarita Pagano, Valentina Manzo, Ines Mazza, Francesco Sabbatino, Graziamaria Corbi, Pasquale Pagliano, Amelia Filippelli, Valeria Conti

“…Protease inhibitors, followed by nonnucleoside reverse transcriptase inhibitors and integrase inhibitors have been recognized as the main players in DDIs with antivirals used to control co-infection, such as Hepatitis C virus, or with drugs commonly used to treat HIV comorbidities, such as lipid-lowering agents, proton pump inhibitors and anticancer drugs. …”
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Gingival Anaplastic Large-Cell Lymphoma Mimicking Hyperplastic Benignancy as the First Clinical Manifestation of AIDS: A Case Report and Review of the Literature by Rafaela Elvira Rozza-de-Menezes, Stefânia Jeronimo Ferreira, Diogo Lenzi Capella, Stephan Schwartz, Ana Helena Willrich, Lúcia de Noronha, Aline Cristina Batista Rodrigues Johann, Paulo Henrique Couto Souza

“…Further laboratory tests revealed positivity for human immunodeficiency virus (HIV). The patient was submitted to chemotherapy, but four months after diagnosis, the patient died due to pneumonia and respiratory failure. …”
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A Performance Evaluation and Inter-laboratory Comparison of Community Face Coverings Media in the Context of COVID-19 Pandemic by Soleiman Bourrous, Mathieu Barrault, Victor Mocho, Stéphane Poirier, Nathalie Bardin-Monnier, Augustin Charvet, Dominique Thomas, Alexandre Bescond, Axel Fouqueau, Tatiana Mace, François Gaie-Levrel, François-Xavier Ouf

“…To ensure the quality of such devices and their relevance to slow down the virus spreading, a quick reaction of the certification organisms was necessary to fix the minimal acceptable performances requirements. …”
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Impact of pulmonary yoga module on lung capacity of COVID-19 adult survivors by Adarsh Tomar, Sudhanshu Verma

“…Nowadays, yogic practices are being used as a preventive measure against this deadly virus. There is a hypothesis that yoga improves lung capacity significantly, which is a front-line fighter against any pathogens or viruses that intrude inside the body. …”
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Combating COVID-19 and its co-infection by Aspergillus tamarii SP73-EGY using in vitro and in silico Studies by Eman Abdelsalam, Amal Mosad Ibrahim, Ahmed A. El-Rashedy, Mohamed S. Abdel-Aziz, Omnia Kutkat, Faten K. Abd EL-Hady

“…Severe Acute Respiratory Syndrome-2 (SARS-CoV-2) virus is capable of causing severe and fatal diseases. …”
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Curtailing the spread of COVID-19 in Nigeria using digital framework and data driven approaches by Bolanle Adefowoke Ojokoh, Benjamin S. Aribisala, Oluwafemi A. Sarumi, Tobore V. Igbe, Abimbola H. Afolayan, Arome J. Gabriel, Abiola Ezekiel Taiwo, Olatunji M. Omisore, Uchechukwu M. Chukwuocha, Olusola T. Babalola, Tolulope A. Adebayo

“…Some nations managed to mitigate the spread of the virus sufficiently early through implementing digital frameworks and other containment measures. …”
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Validación de métodos serológicos y moleculares para la certificación viral de la materia prima del HEBERTRANS® by Kenia Romero Martínez, Maria Teresa Pérez Guevara, Madeline Blanco de Armas, Liuber Yans Machado Zaldívar, Alicia Fleites Vázquez, Esperanza Sánchez Diéguez

“…Para su certificación viral se emplea el sistema serológico HIV Ab & Ag (DIA.PRO, Italia) y 2 sistemas moleculares desarrollados en Cuba, basados en la reacción en cadena de la polimerasa (PCR) cualitativa para la detección de los virus de la hepatitis C y de inmunodeficiencia humana tipo 1, los cuales deben ser validados para demostrar que funcionan con este tipo de muestras. …”
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AI-Driven Plant Health Assessment: A Comparative Analysis of Inception V3, ResNet-50 and ViT with SHAP for Accurate Disease Identification in Taro by Valeria Maeda-Gutiérrez, Juan José Oropeza-Valdez, Luis C. Reveles-Gómez, Cristian Padron-Manrique, Osbaldo Resendis-Antonio, Luis Octavio Solís-Sánchez, Hector A. Guerrero-Osuna, Carlos Alberto Olvera Olvera

“…This study addresses the challenges of Taro disease identification by employing two key strategies: integrating explainable artificial intelligence techniques to interpret deep learning models and conducting a comparative analysis of advanced architectures Inception V3, ResNet-50, and Vision Transformers for classifying common Taro diseases, including leaf blight and mosaic virus, as well as identifying healthy leaves. The novelty of this work lies in the first-ever integration of SHapley Additive exPlanations (SHAP) with deep learning architectures to enhance model interpretability while providing a comprehensive comparison of state-of-the-art methods for this underexplored crop. …”
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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution. by Nicolas Tessandier, Baptiste Elie, Vanina Boué, Christian Selinger, Massilva Rahmoun, Claire Bernat, Sophie Grasset, Soraya Groc, Anne-Sophie Bedin, Thomas Beneteau, Marine Bonneau, Christelle Graf, Nathalie Jacobs, Tsukushi Kamiya, Marion Kerioui, Julie Lajoie, Imène Melki, Jean-Luc Prétet, Bastien Reyné, Géraldine Schlecht-Louf, Mircea T Sofonea, Olivier Supplisson, Chris Wymant, Vincent Foulongne, Jérémie Guedj, Christophe Hirtz, Marie-Christine Picot, Jacques Reynes, Vincent Tribout, Édouard Tuaillon, Tim Waterboer, Michel Segondy, Ignacio G Bravo, Nathalie Boulle, Carmen Lía Murall, Samuel Alizon

“…We performed 974 on-site visits for a total of 1,619 months of follow-up. We collected data on virus load, local immune cell populations, local concentrations of cytokines, and circulating antibody titres. …”
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COVID-19 EM PEDIATRIA: PERFIL EPIDEMIOLÓGICO DOS CASOS SUSPEITOS by Khétene Joyce Freitas Zacarias, Victoria Liery Ribeiro Alves, Yure Batista de Sousa, Mirela Lopes Figueiredo, Ana Augusta Maciel de Souza, Patrícia Fernandes do Prado

“…Dentre as 268 crianças inclusas, 14 (5.22%) foram diagnosticadas com presença de antígenos do vírus SARS-CoV-2. Os resultados permitem concluir que houve maior prevalência da faixa etária 0 a 2 anos (53.36%), do sexo masculino (57.47%) e da raça/cor parda (68.65%). …”
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A Study of Molecular Mimicry and Immunological Cross-reactivity between Hepatitis B Surface Antigen and Myelin Mimics by Dimitrios-Petrou Bogdanos, Heather Smith, Yun Ma, Harold Baum, Giorgina Mieli-Vergani, Diego Vergani

“…On the basis of the reported association between hepatitis B vaccination (HBvacc) and autoimmune demyelinating complications such as multiple sclerosis (MS), we have looked for aminoacid similarities between the small hepatitis B virus surface antigen (SHBsAg), and the MS-autoantigens myelin basic protein (MBP) and myelin oligodendrocyte glycoprotein (MOG) that could serve as targets of immunological cross-reactivity. …”
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