Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study by Seyed Moayed Alavian, Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena HL Borba, Asma Sabermahani, Behzad Hajarizadeh

“…Introduction Low-cost generic direct-acting antiviral (DAA) regimens for treatment of hepatitis C virus (HCV) are available in several low-income/middle-income countries, important for treatment scale-up. …”
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Association between medication adherence and disease outcomes in patients with hepatitis B-related cirrhosis: a population-based case–control study by Vivian Chia-Rong Hsieh, Kuo-Yu Fu, Meng-Lun Hsieh, Jou-An Chen

“…Similar results are observed for the adjusted likelihood of mortality (log 1-year MPR OR: 0.70, 95% CI: 0.68 to 0.72).Conclusions Long-term patient adherence to oral antiviral therapy remains inadequate in patients with hepatitis B virus-related cirrhosis. Their adherence to oral antiviral therapy appears to be inversely associated with decompensation and mortality.…”
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On the nature of picobirnaviruses by A. Yu. Kashnikov, N. V. Epifanova, N. A. Novikova

“…The picobirnaviruses (Picobirnaviridae, Picobirnavirus, PBVs) are currently thought to be animal viruses, as they are usually found in animal stool samples. …”
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Sick leave and disability pension in patients with chronic hepatitis C compared with a matched general population: a nationwide register study by Matti Sällberg, Katharina Büsch, Fredrik Hansson, Michelle Holton, Martin Lagging, Johan Westin, Jan Kövamees, Jonas Söderholm

“…Objective The objective of this study was to evaluate sick leave and disability pension in patients with chronic hepatitis C virus (HCV) infection as compared with a matched general population cohort.Design Retrospective register study.Setting Nationwide in Sweden.Participants This register-based study used the Swedish National Patient Register to identify working-age patients with HCV in 2012 (n=32 021) who were diagnosed between 1999 and 2007 (n=19 362). …”
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Roles of mobile teams in tracing lost to follow–up clients: evidence from the optimization of COVID-19 vaccination uptake and routine immunization in Ekiti State by Saheed Dipo Isiaka, Dapo Awobeku, Akolade Uthman Jimoh, Mahfus Dauda, Olugbemisola Wuraola Samuel, Stephen Olabode Asaolu, Oluwafisayo Azeez Ayodeji, Sunday Atobatele, Segun Adenipekun, Chukwudinma Okoh, Zubair Adegoke, Sidney Sampson

“…Abstract Background Evidence from literature has established that tracing lost to follow-up clients is an effective strategy for complementing other mechanisms for infectious disease control like human immunodeficiency virus (HIV), tuberculosis, and other diseases such as Ebola. …”
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A network medicine approach to investigating ME/CFS pathogenesis in severely ill patients: a pilot study by Li-Yuan Hung, Chan-Shuo Wu, Chia-Jung Chang, Peng Li, Kimberly Hicks, Joshua J. Dibble, Braxton Morrison, Chimere L. Smith, Ronald W. Davis, Wenzhong Xiao

“…Our pathway analysis revealed potential associations between ME/CFS and conditions such as COVID-19, Epstein–Barr virus (EBV) infection, neurodegenerative diseases, and pathways involved in cortisol synthesis and secretion, supporting the hypothesis that ME/CFS is a neuroimmune disorder. …”
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Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury by Jessica M. Herrera, Yun Weng, Tyler J. Lieberthal, Marcus Paoletti, Tammy T. Chang

“…Rock1 fl/fl , Rock2 fl/fl , and Rock1 fl/fl ; Rock2 fl/fl mice were given adeno-associated virus serotype 8 (AAV8)-thyroid hormone-binding globulin (TBG)-Cre to produce targeted gene deletion in hepatocytes, or given AAV8-TBG-Null to generate littermate controls (WT). …”
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Manifestaciones digestivas en pacientes hospitalizados con la COVID-19 by Cesar Abrahan Aguero Figueredo, Moyra Agüero Figueredo, Yenier López Barrero, Lilian Zúñiga Fernández

“…Nuevas cepas diferentes a la variante original del virus, ya han sido identificadas, lo que pudiera significar un cambio en sus patrones de presentación clínica. …”
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Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraep... by Fei Chen, Jinghe Lang, Peter Hillemanns, Youzhong Zhang, Zoltán Novák, Long Sui, Ling Han, Christian Dannecker, Ctirad Mokráš, Zhixue You

“…Introduction High-risk human papilloma virus (HPV)-associated cervical cancer is the fourth most common cancer in women worldwide. …”
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CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production by Emily E. O’Driscoll, Sakshi Arora, Jonathan F. Lang, Beverly L. Davidson, Ophir Shalem

“…Recombinant adeno-associated virus (rAAV) vectors are an effective and well-established tool in the growing gene therapy field, with five U.S. …”
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Simultaneous determination of nirmatrelvir, ritonavir, and beta-D-N4-hydroxycytidine in human plasma and epithelial lining fluid using LC-MS/MS and its clinical application to comp... by Wenjing Zhang, Lin Xia, Zhilong Yuan, Mengdan Liu, Yang Jiao, Zhuo Wang

“…By setting target plasma concentrations of 292 ng/mL for nirmatrelvir and 1205 ng/mL for NHC, based on in vitro antiviral 90 % virus inhibitory concentrations (EC90), the drug's molecular weight and its binding to human plasma proteins, we observed that ritonavir-boosted nirmatrelvir had substantially greater rates of achieving target plasma concentrations. …”
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Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 by Leisha D. Nolen, Courtney Gustin, Sara Seeman, Neil Murphy, Sarah Truitt, Sarah Schillie, Michael G. Bruce, Dana Bruden, James Tiesinga, Brian McMahon

“…Hepatitis C virus (HCV) infection in pregnant women is of concern as it presents a health threat not only to the mother, but also to her infant. …”
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Analysis of oral cancer carcinogens in repeatedly heated cooking oils by Vidhant Krishna Nambiar, Vidya Mudliar, Inosi Salababa

“…The incidence of oral cancer in recent years has been on the rise; ninety percent of the cancers present in the oral cavity are squamous cell carcinoma with multiple major contributing lifestyle factors such well as the presence of the human papilloma virus. Not all mechanisms of carcinogenesis are fully understood and are complex. …”
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A Five-Year Retrospective Study of Foot-and-Mouth Disease Outbreaks in Southern Africa, 2014 to 2018 by Elliot Mpolokang Fana, Sununguko Wata Mpoloka, Melvin Leteane, LaToya Seoke, Kelebogile Masoba, Mokganedi Mokopasetso, Aobakwe Rapharing, Tshephang Kabelo, Patricia Made, Joseph Hyera

“…Foot-and-mouth disease (FMD) virus (FMDv), like other ribonucleic acid (RNA) genome viruses, has a tendency to mutate rapidly. …”
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QSPR/QSAR study of antiviral drugs modeled as multigraphs by using TI’s and MLR method to treat COVID-19 disease by Ugasini Preetha P, M. Suresh, Fikadu Tesgera Tolasa, Ebenezer Bonyah

“…Researchers are actively exploring antiviral treatments to assess their efficacy against emerging virus variants. The aim of the study is to employ M-polynomial, neighborhood M-polynomial approach and QSPR/QSAR analysis to evaluate specific antiviral drugs including Lopinavir, Ritonavir, Arbidol, Thalidomide, Chloroquine, Hydroxychloroquine, Theaflavin and Remdesivir. …”
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Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice by Ying Huang, Haiying Hu, Ling Liu, Jing Ye, Zhen Wang, Bin Que, Wenjing Liu, Ying Shi, Tao Zeng, Lei Shi, Qingwei Ji, Chao Chang, Yingzhong Lin

“…Interleukin- (IL-) 35, a novel functional cytokine of regulatory T cells (Treg) comprised of the IL-12p35 subunit and the other subunit Epstein-Barr virus-induced gene 3 (EBI3), regulates the activity of CD4+ T cells and macrophages, thereby playing a critical role in inflammatory and autoimmune diseases. …”
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The transcriptome of MHV‐infected RAW264.7 cells offers an alternative model for macrophage innate immunity research by Yun Liu, Ting‐Ting Feng, Wei Tong, Zhi Guo, Xia Li, Qi Kong, Zhi‐Guang Xiang

“…Methods In the current in vitro research, murine macrophage RAW 264.7 cell were infected by mouse hepatitis virus, a coronavirus existed in mouse. At 3‐, 6‐, 12‐, 24‐, and 48‐h post infection (hpi.), the attached cells were washed with PBS and harvested in Trizol reagent. …”
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Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon by Ornella J. T. Ngalani, Armelle T. Mbaveng, Wiliane J. T. Marbou, Roland Y. Ngai, Victor Kuete

“…Human immunodeficiency virus (HIV) infection is a serious problem throughout the world and especially in developing countries. …”
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Hepatitis B care cascade among people with HIV/HBV coinfection in the North American AIDS Cohort Collaboration on Research and Design, 2012-2016. by Jessica Kim, Craig W Newcomb, Dean Carbonari, Jessie Torgersen, Keri N Althoff, Mari M Kitahata, Marina B Klein, Richard D Moore, K Rajender Reddy, Michael J Silverberg, Angel M Mayor, Michael A Horberg, Edward R Cachay, Joseph K Lim, M John Gill, Kara Chew, Timothy R Sterling, Mark Hull, Eric C Seaberg, Gregory D Kirk, Sally B Coburn, Raynell Lang, Kathleen A McGinnis, Kelly A Gebo, Sonia Napravnik, H Nina Kim, Vincent Lo Re, North American AIDS Cohort Collaboration on Research and Design of IeDEA

“…However, there have been few data describing the hepatitis B virus (HBV) care cascade among people living with HIV infection who have HBV coinfection. …”
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Real-World Assessment of Weight Change in People with HIV-1 After Initiating Integrase Strand Transfer Inhibitors or Protease Inhibitors by Yen-Wen Chen, Helene Hardy, Christopher D. Pericone, Wing Chow

“…**Background:** Studies have shown an increase in weight among people living with human immunodeficiency virus (PLWH) who have also initiated integrase strand transfer inhibitors (INSTI). …”
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