An adenoviral vector encoding an inflammation-inducible antagonist, HMGB1 Box A, as a novel therapeutic approach to inflammatory diseases by Kari Ann Shirey, John Joseph, Lynda Coughlan, Haye Nijhuis, Alan W. Varley, Jorge C. G. Blanco, Stefanie N. Vogel

“…ABSTRACT Influenza, as well as other respiratory viruses, can trigger local and systemic inflammation resulting in an overall “cytokine storm” that produces serious outcomes such as acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). …”
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New Onset of Diabetes Mellitus and Associated Factors among COVID-19 Patients in COVID-19 Care Centers, Addis Ababa, Ethiopia 2022 by Asaminew Habtamu Sane, Migbar Sibhat Mekonnen, Melsew Getnet Tsegaw, Wuletaw Chane Zewde, Edmialem Getahun Mesfin, Hailu Asmare Beyene, Taye Mezgebu Ashine, Kasie Gebeyehu Tiruneh, Melkie Ambaw Mengistie

“…Existing evidence showed that new-onset diabetes is associated with increased mortality compared to nondiabetic and known diabetic patients in the COVID-19 era. SARS-CoV-2 virus can worsen existing diabetes; at the same time, it can trigger new-onset diabetes that eventually worsens patient outcomes. …”
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Prevalence and phylogenetic analysis of cytomegalovirus (Orthoherpesviridae: <i>Cytomegalovirus: Cytomegalovirus humanbeta5</i>) genetic variants from children and immunocompromise... by Ol’ga E. Van’kova, Nina F. Brusnigina, Nadezhda A. Novikova

“…Cytomegalovirus (CMV) is a DNA-containing virus that is widespread worldwide and is of great importance in infectious pathology of children and adults. …”
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Lack of Tissue Virological Response as a Predictor of Relapse in Chronic Hepatitis D after Completion Bulevirtide Therapy by P. O. Bogomolov, N. A. Shub, N. A. Gasilova, A. A. Belyakova, T. G. Lidzhieva, E. A. Kondrasheva, N. A. Barsukova, M. V. Arapova, E. A. Isaeva, S. V. Koblov, M. V. Kalashnikov, O. S. Kuzymina, A. Yu. Demyanov, A. O. Bueverov, I. V. Maev

“…Aim: to evaluate the significance of a positive polymerase chain reaction result for hepatitis D virus RNA (HDV RNA) in liver biopsy specimens of patients with chronic hepatitis D (CHD) after completion of antiviral therapy (AVT) as a predictor of infection relapse.Materials and methods. …”
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Transmitted Drug Resistance among People Living with HIV/Aids at Major Cities of Sao Paulo State, Brazil by Joao Leandro Paula Ferreira, Rosangela Rodrigues, Andre Minhoto Lança, Valeria Correia de Almeida, Simone Queiroz Rocha, Taisa Grotta Ragazzo, Denise Lotufo Estevam, Luis Fernando de Macedo Brigido

“…Human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) is an important public health issue. …”
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Under simulated microgravity and gravity, anthocyanin is regulated by DcaWRKY2 in Dendrobium catenatum leaves by Tianze Hou, Baoqiang Zheng, Fucheng Peng, Zehui Jiang, Wenbo Zhang, Yan Wang

“…A more in-depth analysis evaluating the function of DcaWRKY2, transcription factor gene DcaWRKY2, was silenced by virus-induced gene silencing under gravity conditions, which resulted in the increase of anthocyanin accumulation in leaves, and the expression levels of anthocyanin biosynthesis pathway (ABP) structural genes, including DcaCHS, DcaCHI, DcaF3H, DcaDFR, and DcaANS were increased significantly. …”
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Insights Into the Role of Bmi‐1 Deregulation in Promoting Stemness and Therapy Resistance in Glioblastoma: A Narrative Review by Fatima Shaalan, Nissrine Ballout, Wafaa Takash Chamoun

“…B‐cell‐specific Moloney murine leukemia virus insertion site‐1 (Bmi‐1) is a member of the highly conserved polycomb group (PcG) protein family that acts as a transcriptional repressor of multiple genes, including those that determine cell proliferation and differentiation. …”
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Epidemiological Features, Clinical Symptoms, and Environmental Risk Factors for Notifiable Japanese Encephalitis in Taiwan From 2008 to 2020: Retrospective Study by Fu-Huang Lin, Yu-Ching Chou, Chi-Jeng Hsieh, Chia-Peng Yu

“… Abstract BackgroundJapanese encephalitis (JE) is a zoonotic parasitic disease caused by the Japanese encephalitis virus (JEV), and may cause fever, nausea, headache, or meningitis. …”
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Geospatial distribution of Hepatitis E seroprevalence in Nepal, 2021. by Chulwoo Rhee, Amy Dighe, Nishan Katuwal, Haeun Cho, Ramzi Mraidi, Dipesh Tamrakar, Jacqueline KyungAh Lim, Nimesh Poudyal, Il-Yeon Park, Deok Ryun Kim, Ritu Amatya, Rajeev Shrestha, Andrew S Azman, Julia Lynch

“…<h4>Background</h4>Hepatitis E virus (HEV) causes acute jaundice and poses an important public health problem in low- and middle-income countries. …”
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Semi-field experiments reveal contrasted predation and movement patterns of aquatic macroinvertebrate predators of Anopheles gambiae larvae by Hudson Onen, Emmanuel W. Kaindoa, Joel Nkya, Alex Limwagu, Martha A. Kaddumukasa, Fredros O. Okumu, Jonathan K. Kayondo, Anne M. Akol, Frédéric Tripet

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Inhibition of Endothelial–Mesenchymal Transition Mediated by Activin Receptor Type IIA Attenuates Valvular Injury Induced by Group A Streptococcus in Lewis Rats by Zirong Lu, Yuan Li, Chuanghong Lu, Zhongyuan Meng, Ling Bai, Feng Huang, Zhiyu Zeng

“…We constructed a small interfering RNA (ACVR2A-siRNA) by silencing activin receptor type IIA (ACVR2A) and an adeno-associated virus (AAV-ACVR2A) containing a sequence that silenced ACVR2A. …”
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Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review by Paul Little, Simon J Griffin, Hajira Dambha-Miller, Nazrul Islam, Ali Albasri, Christopher R Wilcox, Sam Hodgson, Shareen Khan

“…Our review indicates that the impact of currently prescribed drugs on ACE2 has been poorly studied in vivo, particularly in human lungs where the SARS-CoV-2 virus appears to enact its pathogenic effects. We found no convincing evidence to justify starting or stopping currently prescribed drugs to influence outcomes of COVID-19 disease.…”
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Caracterización de pacientes diagnosticados de carcinoma epidermoide de canal anal. Cienfuegos, 2017-2019 by Yeidy Santos Toledo, Jorge Luis Estepa Pérez, José Antonio Feliú Rosa, Tahiluma Santana Pedraza, Daniel Alejandro Díaz Conde

“…<br /><strong>Resultados:</strong> predominaron pacientes en edades entre 50 y 70 años, femeninas; la rectorragia y el dolor anal fueron los síntomas fundamentales, acompañados o no de cambios en el hábito intestinal, pujo y tenesmo; el virus del papiloma humano fue el antecedente patológico personal más observado; la colostomía fue la técnica quirúrgica más empleada.…”
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NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8+ T Cell Evolution towards Senescence by John Heath, Nicholas Newhook, Emilie Comeau, Maureen Gallant, Neva Fudge, Michael Grant

“…Expansion of NKG2C+CD57+ NK was measured in peripheral blood mononuclear cells (PBMC) from groups distinguished by HCMV and human immunodeficiency virus (HIV) infection status. Anti-HCMV antibody levels against HCMV-infected MRC-5 cell lysate were assessed by ELISA and HCMV-specific CD8+ T cell responses characterized by intracellular flow cytometry following PBMC stimulation with immunodominant HCMV peptides. …”
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High-Resolution Microscopic Images of Mosquito Vectors (Diptera: Culicidae): Proper Identification of Culex and Aedes during Dengue Outbreak Situation in Bangladesh by Farzana Yesmin, Md. Fahad Hasan, Tahera Hossain, Shamme Akter, Md Nazim Uddin, Md. Hasanuzzaman

“…Results obtained in this study revealed that dengue virus can also be carried by other Aedes species rather than A. aegypti. …”
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Genistein Attenuates Lipopolysaccharide-Induced Hepatic Oxidative Stress and Inflammatory Responses in Turbot (Scophthalmus maximus L.) Juveniles by Xiao-qian Zhou, Zi-yan Shi, Hai-hong Chen, Xin Xiao, Dan Xu, Zhi-jie Dan

“…Furthermore, the main signaling pathways associated with inflammation included Herpes simplex virus 1 infection, RIG-I-like receptor, NOD-like receptor, C-type lectin receptor, and p53 signaling pathways. …”
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Integrating hepatitis B care and treatment with existing HIV services is possible: cost of integrated HIV and hepatitis B treatment in a low-resource setting: a cross-sectional hos... by Andrew Kambugu, Philippa Easterbrook, Jacinto Amandua, David Livingstone Ejalu, Joan N Mutyoba, Claude Wandera, Emmanuel Seremba, Alex Muganzi, Racheal Beyagira, Kaggwa Mugagga, Ponsiano Ocama

“…Data were extracted from 3121 files of HIV and hepatitis B virus (HBV) monoinfected patients from the two study sites.Objective To estimate provider costs associated with running an integrated HBV and HIV clinical pathway for patients on lifelong treatment in low-resource setting in Uganda.Outcome measures The annual cost per patient was simulated based on the total amount of resources spent for all the expected number of patient visits to the facility for HBV or HIV care per year.Results Findings showed that Arua hospital had a higher cost per patient in both clinics than did Koboko Hospital. …”
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Sources of HIV information and women’s HIV knowledge in Southwest Sumba Indonesia: a cross-sectional study with mediation analysis by Angela Kurniadi, Judith A. Levy, Timothy P. Johnson

“…Most incorrect answers pertained either to Mother-to-Child HIV Transmission (MTCT) or misconceptions about the virus. One-way ANOVA revealed that the mean of HIV knowledge increased as the number of informational sources increased (p < .001). …”
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Frequency of Lower Lung Field Tuberculosis in Diabetes Mellitus Patients Attending Tertiary Care Hospital in Bangladesh: A Cross‐Sectional Study by Raihan Kamal Galib, Susanta Kumar Paul, Khujjista Akter, Manzurul Ibrahim Musa, Dip Jyoti Sarker, Shah Ashiqur Rahman Ashiq Choudhury, Shipan Chandra Paul, Rajashish Chakrabortty

“…Extrapulmonary tuberculosis and seropositive human immunodeficiency virus (HIV) were excluded from this study. A chest x‐ray posterior‐anterior (P/A) view was done to assess the frequency and patterns of lung involvement. …”
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Relación entre el proceso evolutivo del ser humano y su predisposición al cáncer by Armando Ernesto Pérez Cala, Edgar Benítez Sánchez, Dunia García Massó

“…La conducta sexual incrementó el riesgo de contraer infecciones por virus oncogénicos. El paso a una predominantemente cárnica y la introducción de la cocción, se tradujo en la incorporación de agentes xenobióticos cuyo metabolismo deriva agentes carcinógenos. …”
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