Resistance-Associated Substitutions (RAS) and Clinical Factors as Determinants of Sofosbuvir-Daclatasvir Treatment Outcomes in Chronic Hepatitis C Patients by Juferdy Kurniawan, Anugrah Dwi Handayu, Gita Aprilicia, Darlene Raudhatul Bahri, Irsan Hasan

“…Methods: We conducted a prospective longitudinal study in naïve hepatitis C patient population. The virus was examined for RAS by RNA sequencing before starting treatment. …”
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From fibrosis to granuloma: drug induced systemic sarcoidosis-like reaction after rituximab in a patient with primary Sjögren’s syndrome by Rui Rua Coelho, Sara Xavier Pires, José Ricardo Brandão, Inês Furtado

“…Moreover, granulomatous lymphocytic interstitial lung disease associated with common variable immunodeficiency and immune reconstitution syndrome in patients wirh human immunodeficiency virus show clinical similarities to DISR and can help unveil new cytogenic and physiologic pathways. …”
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Incidence and Predictors of Pulmonary Tuberculosis among Children Who Received Antiretroviral Therapy (ART), Northwest Ethiopia: A Multicenter Historical Cohorts Study 2009–2019 by Fassikaw Kebede, Habtamu Tarekegn, Mulugeta Molla, Dube Jara, Abebe Abate

“…The human immune deficiency virus (HIV) is the strongest risk factor for endogenous reactivation of pulmonary tuberculosis (PTB) through target reduction of CD4, T-lymphocytes, and cellular immune function. …”
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Modelling COVID-19 in the North American region with a metapopulation network and Kalman filter by Matteo Perini, Teresa K. Yamana, Marta Galanti, Jiyeon Suh, Roselyn Kaondera-Shava, Jeffrey Shaman

“…Methods: We developed a novel metapopulation model for simulating respiratory virus transmission in the North America region, specifically for the 96 states, provinces, and territories of Canada, Mexico, and the United States. …”
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Desenvolvimento do ensino remoto emergencial em uma instituição pública do ensino superior by Maria Denise Nunes Rodrigues, Iasmin Ribeiro Diniz, Mônica Carvalho Alves Cappelle

“… O ano 2020 teve uma realidade imposta e fora do controle da humanidade, tivemos que rever determinados comportamentos, bem como readequar a novos procedimentos, dentre estes, restrições quanto aos contatos sociais, de se manter em distanciamento social, tudo isso por conta de uma pandemia gerada pelo vírus COVID-19. Frente a essa realidade, as instituições de ensino sofreram com a suspensão das aulas e repensarem em uma nova forma de oferecer o ensino, surgindo, por autoridades da educação, o ensino remoto emergencial (ERE). …”
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Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel by Seungkyu Choi, Jai Hyang Go, Eun Kyung Kim, Hojung Lee, Won Mi Lee, Chun-Sung Cho, Kyudong Han

“…Although extranodal NKTCL reportedly has a strong association with Epstein-Barr virus, the molecular pathogenesis of NKTCL has been unexplored. …”
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A comprehensive review and meta-analysis of the relationships between interleukin-7 levels and COVID-19 severity by Michal MATUSZEWSKI, Michal PRUC, Lukasz SZARPAK, Alla NAVOLOKINA, Katarzyna KIEZUN, Francesco CHIRICO, Gabriella NUCERA, Yuriy STEPANOVSKYY, Murat YILDIRIM, Anna HILFANOVA, Anastasia BONDARENKO

“…Despite the first hyper-inflammatory phase, emerging data show that virus-induced poor host immunity may be the true cause of mortality in many individuals. …”
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Refractory human cytomegalovirus infection without evidence of genetic resistance in the UL-54 and UL-97 genes in a pediatric hematopoietic stem cell transplant recipient: a case r... by Alejandra Pando-Caciano, Ketty Adid Escudero-Ramirez, Jackeline Carol Rodríguez-Torres, Holger Maita-Malpartida, Holger Maita-Malpartida

“…Furthermore, this case highlights the importance of using highly sensitive genetic tools to detect mutations associated with virus resistance in a broader range of the viral genome.…”
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Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases by Daniele del Re, Luigi Palla, Paolo Meridiani, Livia Soffi, Michele Tancredi Loiudice, Martina Antinozzi, Maria Sofia Cattaruzza

“…., the number of new positive cases, deaths and hospitalizations, have been used to monitor virus spread, but all suffer from biases. The aim of this study was to evaluate an alternative data source from Emergency Medical Service (EMS) activities for COVID-19 monitoring. …”
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Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses by Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

“…To evaluate the clinical usefulness of these EVs, we measured the serum levels in patients with inflammatory diseases, including Epstein-Barr virus (EBV, n=13) infection, atopic dermatitis (AD, n=10), rheumatoid arthritis (RA, n=20), and osteoarthritis (OA, n=20) and compared the levels with those of healthy adults (n=20). …”
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Squamous cell carcinoma in a kidney transplant recipient after 26 years by Carolina da Silva Nunes, Andreia Bufalino, Cláudia Maria Navarro, Jorge Esquiche León, Héric de Souza Camargo, Elaine Maria Sgavioli Massucato

“…The oral cavity is a predilection site in the head and neck region, and many lesions are associated with human papillomavirus (HPV), an oncogenic virus whose infection can be potentiated by chronic immunosuppression in transplant patients. …”
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NS5A replication complex inhibitor daclatasvir in the basis of chronic hepatitis C interferon-free therapy by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

“…Daclatasvir is NS5A inhibitor which has proven high antiviral activity in relation to all hepatitis C virus genotypes. Prescription of the drug in combination to pegilated interferon and ribavirin for treatment-naive patients made possible to reduce treatment duration from 48 to 24 weeks and to increase frequency of sustained virologic response (SVR) to 87% in 1b genotypeand to 100% — in 4-th genotype. …”
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RETRACTED ARTICLE: Impact TB co-infections on immune tolerance among people living with HIV: a systematic review by Yimam Getaneh, Siti qamariyah Khairunisa, Dominicus Husada, Kuntaman Kuntaman, Maria Inge Lusida

“…Novel developments in the epidemic of human immunodeficiency virus and tuberculosis coinfection. Am J Respir Crit Care Med. 2011 Apr 15;183(8):987-97. https://www.atsjournals.org/doi/full/10.1164/rccm.201008-1246CI Figure 2 and the associated caption in the above article are from Sharan, R., Bucşan, A. …”
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Segurança microbiológica de hortaliças orgânicas no Brasil by Karina Rosa Morgado, Mariana Guedes Resende da Silva, Rafaela Anjos Fagundes Evaristo, Roger Santos Souza, Hilana Ceotto Vigoder

“…Tendo em vista as práticas relacionadas à agricultura orgânica, principalmente o uso de fertilizantes a base de esterco compostado em substituição aos fertilizantes sintéticos, o risco de contaminação microbiológica de hortaliças, durante a sua produção, o controle microbiológico das hortaliças orgânicas é essencial a fim de se garantir a sua qualidade e evitar surtos de DTAs (Doenças Transmitidas por Alimentos). Apesar dos vírus serem os seus agentes mais comuns, as bactérias representam os casos mais graves, podendo levar a hospitalizações e mortes. …”
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Impact of Comorbidities on the Severity of Disease & Outcome in Children with COVID 19 at a Tertiary Care Pediatric Hospital, Rawalpindi. by Rai Muhammad Asghar, Muddassar Sharif, Khalid Saheel, Isfandyar Khan, Abid Hussain, Rai Rijjal Ashraf

“… Introduction: Coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was initially identified in Wuhan, China, in December 2019. The virus affects almost all countries of the world. …”
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Histopathology of the tongue in a hamster model of COVID-19 by John Coggins, Marina Hosotani Saito, Rebecca Cook, Shinji Urata, Megumi Urata, Nantian Lin Harsell, Wilhelmina Nanrui Tan, Bibiana Toro Figueira, Megan Bradley, Nadia Z. Quadri, Janisah Amirah I. Saripada, Rachel A. Reyna, Junki Maruyama, Slobodan Paessler, Tomoko Makishima

“…Conclusion The presence and distribution of SARS-CoV-2 suggest that the virus could cause taste disturbance by infecting the vallate papillae taste buds. …”
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Cross-Cultural Sense-Making of Global Health Crises: A Text Mining Study of Public Opinions on Social Media Related to the COVID-19 Pandemic in Developed and Developing Economies by Adham Kahlawi, Firas Masri, Wasim Ahmed, Josep Vidal-Alaball

“…MethodsA total of 755,215 social media posts from X (formerly Twitter) were collected across 3 time periods: the virus' emergence (February 15 to March 31, 2020), strict lockdown (April 1 to May 30, 2020), and the vaccine rollout (December 1, 2020 to January 15, 2021). …”
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Procalcitonin and High APACHE (Acute Physiological and Chronic Health Evaluation) Level Are Associated with the Course of Acute Kidney Injury in Patients with SARS-CoV-2 by Jorge Andrade Sierra, Claudia Delgado Astorga, Miriam Gabriela Nava Vargas, Enrique Rojas Campos, Kevin Javier Arrelano Arteaga, Karla Hernández Morales, Carlos A. Andrade Castellanos, Antonio de Jesús Andrade-Ortega, Luis Gerardo González Correa

“…Sepsis, direct injury to kidney cells by the virus, and severe systemic inflammation are mechanisms implicated in its development. …”
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Sexual Health Advocacy for Guys (SHAG): a randomized trial of the impact of a text-messaging program on HIV incidence and STI testing among a national sample of sexual minority cis... by M. L. Ybarra, D. J. Feaster, R. Garofalo, S. Bull

“…Abstract Background Disparities in sexually transmitted infections (STI) including human immunodeficiency virus (HIV) among sexual minority boys and young men are substantial. …”
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African swine fever in the Primorsky Krai: disease situation and molecular and biological properties of the isolate recovered from a wild boar long bone by А. R. Shotin, A. S. Igolkin, Ali Mazloum, I. V. Shevchenko, N. S. Bardina, E. O. Morozova, А. А. Shevtsov

“…It is necessary to continue the analysis of the situation and molecular and biological properties of the current African swine fever virus isolates, recovered in the Russian border territories to cover the following tasks: eradication of African swine fever; development of effective disease surveillance and control programs; search for promising genome markers for the vaccine development; implementation of the differentiation strategy between vaccinated and non-vaccinated animals; and clustering of the isolates. …”
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