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761
Biological Characteristics and Whole-Genome Analysis of a Porcine <i>E. coli</i> Phage
Published 2025-01-01“…No known resistance, lysogenic, or virulence-related genes were detected. The whole genome contains 55 open reading frames (ORFs). (4) Conclusions: This study isolated a bacteriophage that is capable of lysing multidrug-resistant <i>E. coli</i>. …”
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762
Comparative transcriptomics reveal stage-dependent parasitic adaptations in the myxozoan Sphaerospora molnari
Published 2025-02-01“…Notably, we identified genes that are similar to known virulence factors in other parasitic organisms, particularly blood and intestinal parasites like Plasmodium, Trypanosoma, and Giardia. …”
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763
Probiotic potential and safety properties of Limosilactobacillus fermentum A51 with high exopolysaccharide production
Published 2025-01-01“…Hemolysis and antibiotic resistance tests, combined with the analysis of genes involved in antibiotic resistance, virulence factor, and hemolysins, suggested that L. fermentum A51 is safe. …”
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764
Host–virus interactions during infection with a wild-type ILTV strain or a glycoprotein G deletion mutant ILTV vaccine strain in an ex vivo system
Published 2025-02-01“…The glycoprotein G (gG) of ILTV is a virulence factor and a chemokine-binding protein with immunoregulatory functions. …”
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765
Antibiotic susceptibility and molecular characterization based on whole-genome sequencing of Staphylococcus aureus causing invasive infection in children and women living in Southw...
Published 2025-01-01“…Most isolates carried common virulence genes, among which the carriage rate of pvl reached 33.33%. …”
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766
Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination
Published 2025-02-01“…GAS, especially skin-tropic bacterial strains, utilize specific virulence factors, plasminogen binding M-protein (PAM) and streptokinase (SK), to manipulate hemostasis and activate plasminogen to cause fibrinolysis and fibrin clot escape. …”
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767
Deciphering the functional roles of PE18 and PPE26 proteins in modulating Mycobacterium tuberculosis pathogenesis and immune response
Published 2025-01-01“…A crucial factor in Mtb's virulence is the ESX-5 secretion system, which transports PE/PPE proteins such as PE18 and PPE26. …”
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768
Diversity and Complexity of CTXΦ and Pre-CTXΦ Families in <em>Vibrio cholerae</em> from Seventh Pandemic
Published 2024-09-01“…CTXΦ is a lysogenic filamentous phage that carries the genes encoding cholera toxin (<i>ctxAB</i>), the main virulence factor of <i>Vibrio cholerae</i>. The toxigenic conversion of environmental <i>V. cholerae</i> strains through CTXΦ lysogenic infection is crucial for the emergence of new pathogenic clones. …”
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769
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770
Engineering a live-attenuated porcine reproductive and respiratory syndrome virus vaccine to prevent RNA recombination by rewiring transcriptional regulatory sequences
Published 2025-02-01“…Vaccine strains are also involved in PRRSV recombination, which leads to the emergence of new variants and alterations in virulence and pathogenesis. A recombination-resistant genome was engineered by rewiring the entire transcriptional regulatory sequence (TRS) circuit of the live PRRSV vaccine strain. …”
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771
Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming
Published 2025-01-01“…These rods can vary in phenotypic characteristics and virulence levels.DiscussionThe research conducted allows to draw attention to the occurrence of pathogens, including L. monocytogenes in crops from organic farming. …”
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772
Prevalence of common diarrheagenic enterobacteriaceae in Iran (2000–2023): a systematic review and meta-analysis
Published 2025-01-01“…Further research should investigate the factors contributing to the prevalence of diarrheagenic Enterobacteriaceae, including genetic diversity of diarrheagenic Enterobacteriaceae isolates, molecular mechanisms underlying the virulence of these pathogens, or antibiotic resistance patterns.…”
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773
Stem rust in Western Siberia – race composition and effective resistance genes
Published 2020-04-01“…A low frequency of virulence (10–25 %) of the Omsk population pathotypes was found for Sr11, Sr24,Sr30, and for Altai population – Sr7b,Sr9b,Sr11,SrTmp, which are ineffective in Omsk region. …”
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774
Sdd3 regulates the biofilm formation of Candida albicans via the Rho1-PKC-MAPK pathway
Published 2025-02-01“…As an upstream component of the pathway and lacking a homolog in mammals, Sdd3 has the potential to serve as an antifungal target for biofilm infections.IMPORTANCEThe human fungal pathogen Candida albicans is categorized as a critical priority pathogen on the World Health Organization’s Fungal Priority Pathogens List. A key virulence attribute of this pathogen is its ability to form biofilms on the surfaces of indwelling medical devices. …”
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775
Kloning gen virulen Streptococcus agalactiae sebagai bahan dasar vaksin rekombinan
Published 2016-12-01“…Mga is DNA-binding protein that activates expression of several important virulence gene, including those encoding M protein (emm), C5a peptidase (SCPA) and mga. …”
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776
Spatiotemporal analysis of Plasmodium falciparum erythrocyte binding antigen-175 gene dimorphism in Ghana
Published 2025-01-01“…EBA-175 is known to exist in two dimorphic allelic (F and C) forms with each found to infer different virulence. There is paucity of data on the prevalence of these alleles and their epidemiology in the Ghanaian malaria landscape and hence this study. …”
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777
Genetic and Molecular Characterization of Avian Influenza A(H9N2) Viruses from Live Bird Markets (LBM) in Senegal
Published 2025-01-01“…The A/H9N2 strains carried the low pathogenicity RSSR/GLF motif at the HA cleavage site and possessed several key amino acid mutations, including HA-I155T and HA-Q226L, which are associated with human host adaptation, PB2-T105V, PB2-A661T, and PB2-A588V, which are linked to the human-to-human transmission and increased polymerase activity, NS2-T14M, NS2-M100I, NS1-I106M, NS1-V222M, NS1-E223A, NS1-I226V, NS1-E227G, and NS1-P228S, which are known to alter virulence (increased or reduced) in humans or mice, and M2-S31N, which promotes drug resistance. …”
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