Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region by Weiping Zhou, Xiaoyan Chen, Jie Chen, Xiuhua Zheng, Xueqiang Zhang, Yubin Chen, Yuehua Pan, Chunling Ma

“…Having a college degree or above, absence of pregnancy vomiting, elevated levels of albumin, globulin, direct bilirubin, glutamyl transferase, and total bile acids, and decreased levels of alkaline phosphatase and lactate dehydrogenase are high-risk factors for GBS infection; ST10, ST19, ST529, and ST862 are the main genotypes prevalent in this region; there are regional differences in the distribution of GBS genotypes and CC groups; there are statistically significant differences in the distribution of virulence factors among GBS strains with different MLST genotypes (p<0.05); GBS shows high sensitivity to penicillin drugs and can still be used as the preferred medication for the prevention and treatment of GBS infection.…”
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Whole-genome sequencing surveillance of Siberian tick-borne encephalitis virus (TBEV) identifies an additional lineage in Kyrgyzstan by Jake D'Addiego, Mollie Curran-French, Jack Smith, Asankadyr T Junushov, Irena Breininger, Barry Atkinson, John Hay, Roger Hewson

“…In recent years, other TBEV subtypes have been described, namely the Himalayan and Baikalian subtypes. Differences in virulence between TBEV subtypes have been described, with the Far Eastern subtype causing the most severe disease in humans. …”
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Genomic characteristics and phylogenetic relationships of Cutibacterium acnes breast milk isolates by Jiaqi Sun, Guoxuan Hang, Huimin Lv, Yu Li, Qiujie Song, Zhi Zhong, Zhihong Sun, Wenjun Liu

“…In this study, the sequencing and assembly results of 10 C. acnes isolates from breast milk were compared with the genomic data of 454 strains downloaded from NCBI, and the characteristics of breast milk isolates from various perspectives, including phylogeny, genomic characteristics, virulence genes, drug resistance genes, and carbohydrate utilization, were elucidated. …”
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Draft genome sequence of a co-harbouring blaNDM-5 and mcr-1.1 Escherichia coli phylogroup A isolate associated with patient colonisation in Ireland by Anna Tumeo, Francesca McDonagh, Aneta Kovarova, Kate Ryan, Christina Clarke, Georgios Miliotis

“…Objectives: While Escherichia coli phylogroup-A is typically associated with commensal strains, some isolates can harbour virulence and exhibit multidrug-resistant (MDR) phenotypes. …”
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Development of ptxD/Phi as a new dominant selection system for genetic manipulation in Cryptococcus neoformans by Muthita Khongthongdam, Tanaporn Phetruen, Sittinan Chanarat

“…Growth assays showed that ptxD integration did not adversely affect cell growth or key virulence factors, including pleomorphism, capsule size, and melanin production. …”
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Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching ho... by Pengyu Zhang, Jingchen Hao, Yafen Zhang, Junfeng Su, Guozhuang Sun, Jun Xie, Jian Hu, Guocai Li

“…Acquired antimicrobial resistance genes and virulence factors carried in the isolated group genome were analyzed by ResFinder, PubMLST and VFDB. …”
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RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection by Yukihiro Hiramatsu, Takashi Nishida, Dendi Krisna Nugraha, Fuminori Sugihara, Yasuhiko Horiguchi

“…This study proposes melanin as a virulence factor involved in the increased survival of B. parapertussis during host infection.…”
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Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development. by Seung-Joo Lee, James B McLachlan, Jonathan R Kurtz, Danhua Fan, Sebastian E Winter, Andreas J Baumler, Marc K Jenkins, Stephen J McSorley

“…Pathogens can substantially alter gene expression within an infected host depending on metabolic or virulence requirements in different tissues, however, the effect of these alterations on host immunity are unclear. …”
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Helicobacter pylori: Genomic Insight into the Host-Pathogen Interaction by Kathryn P. Haley, Jennifer A. Gaddy

“…Together, these techniques have revealed novel virulence determinants in numerous pathogens and have provided information for potential chemotherapeutics. …”
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New Concepts in the Diagnosis and Pathogenesis of Trichomonas vaginalis by Renuka Bhatt, Mary Abraham, Dino Petrin, Gary E Garber

“…There is a need for more accurate and rapid laboratory diagnostic methods, leading to better control and treatment strategies. Various virulence factors such as adherence, contact-independent factors, hemolysis and acquisition of host macromolecules have been shown to play a role in the pathogenesis of this infection. …”
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Comparative Genomic Analysis of Rhodococcus equi: An Insight into Genomic Diversity and Genome Evolution by Jianchao Ying, Jun Ye, Teng Xu, Qian Wang, Qiyu Bao, Aifang Li

“…Moreover, genomic islands in R. equi were always involved in virulence, resistance, or niche adaptation and possibly working with prophages to cause the majority of genome expansion. …”
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Effective anti-adhesives of uropathogenic Escherichia coli by Ribić Rosana, Meštrović Tomislav, Neuberg Marijana, Kozina Goran

“…Although UPEC may harbour a plethora of virulence factors, type I fimbriae and P pili are two of the most studied adhesive organelles, since the attachment to host cells in the urinary tract is a crucial step towards infection. …”
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Future Directions and Molecular Basis of Ventilator Associated Pneumonia by Kubra Aykac, Yasemin Ozsurekci, Sevgen Tanir Basaranoglu

“…All of the bacteria have different pathogenesis due to their different virulence factors and host reactions. This review article focused on mechanisms of VAP with molecular pathogenesis of the causative bacteria one by one from the literature. …”
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Modern approaches to treatment of acute anaerobic paraproctitis by M. A. Yegorkin

“…The majority of researchers agree that anaerobic directivity of inflammatory process at AP is determined by high load and virulence of the infectious agent on a background of decrease of immune resistance of the body. …”
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Morphology of Helicobacter pylori as a result of peptidoglycan and cytoskeleton rearrangements by Paweł Krzyżek, Grażyna Gościniak

“…In addition, the existence of proteins associated with modifications of H. pylori morphology as potential targets in therapies reducing the virulence of this bacterium has been suggested.…”
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2009 H1N1 Influenza by Seth J. Sullivan, MD; Robert M. Jacobson, MD; Walter R. Dowdle, PhD; and Gregory A. Poland

“…The virus has caused disproportionate disease among young people with early reports of virulence similar to that of seasonal influenza. This clinical review provides an update encompassing the virology, epidemiology, clinical manifestations, diagnosis, treatment, and prevention of the 2009 H1N1 virus. …”
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Dissemination of clinical Escherichia coli harboring the mcr-1 gene in Pakistan by Sabahat Abdullah, Sabahat Abdullah, Muhammad Ahmad Mushtaq, Kalim Ullah, Brekhna Hassan, Mariya Azam, Mariya Azam, Muhammad Asif Zahoor, Juan Wang, Jianzhen Xu, Mark A. Toleman, Mashkoor Mohsin

“…The Achtman MLST typing scheme revealed a large diversity of STs among the mcr-1-positive E. coli. VirulenceFinder analysis revealed the presence of numerous virulence factors ranging from 4 to 19.ConclusionOur study revealed the emergence and dissemination of colistin-resistant E. coli isolates carrying mcr-1 in hospital settings, posing a potential risk to anti-infective therapy. …”
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Genome-wide identification of short-chain dehydrogenases/reductases genes and functional characterization of ApSDR53C2 in melanin biosynthesis in Arthrinium phaeospermum by Jiao Liao, Yisi Wang, Han Liu, Sijia Liu, Peng Yan, Hang Chen, Shujiang Li, Shujiang Li

“…The pathogenicity analysis revealed that ApSDR53C2 and ApSDR548U2 play important roles in virulence, with ApSDR53C2 having a stronger effect. …”
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Characterization and molecular detection of pathogenicity and antibiotic resistance genes in Vibrio parahaemolyticus isolated from Pacific white shrimp by Muhammad Arif Mulya, Fachriyan Hasmi Pasaribu, Usamah Afiff, Munti Yuhana

“…The hemolysis test and PCR were applied to detect the presence of virulence genes, namely toxR, thermostable direct haemolysin (tdh), and tdh-related haemolysin (trh). …”
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Niobium Uptake and Release by Bacterial Ferric Ion Binding Protein by Yanbo Shi, Ian Harvey, Dominic Campopiano, Peter J. Sadler

“…Ferric ion binding proteins (Fbps) transport FeIII across the periplasm and are vital for the virulence of many Gram negative bacteria. Iron(III) is tightly bound in a hinged binding cleft with octahedral coordination geometry involving binding to protein side chains (including tyrosinate residues) together with a synergistic anion such as phosphate. …”
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