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581
Specific features of African swine fever control activities in China
Published 2023-09-01“…The country with the largest swine population in the world achieved rather moderate spread rates if compared to Europe.In addition, the virus strains, which circulated in the Chinese territory, were genetically diverse and different in virulence, leading to a wide range of clinical signs manifested by diseased animals. …”
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582
Bioinformatics exploration of identified garlic-derived antimicrobial peptides: a food-based approach to quorum sensing inhibition in foodborne pathogens
Published 2025-01-01“…Quorum Sensing (QS), a bacterial communication system, is critical for controlling virulence factors and biofilm development, contributing to many foodborne bacteria' pathogenicity. …”
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583
Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae.
Published 2025-01-01“…Klebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. …”
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584
Evolution of parasite transmission dispersion
Published 2025-01-01“…Furthermore, parasite adaptation can maintain increased transmission dispersion at endemic equilibria if virulence differs between hosts in a heterogeneous population. …”
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585
Helicobacter pylori Infection in Gastroesophageal Reflux Disease in the Asian Countries
Published 2015-01-01“…The interactions between genetic factors and the virulence of H. pylori infection may be the reason for the low prevalence of GERD in Asian countries. …”
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586
Conservative Women and Feminism in the United States: Between Hatred and Appropriation
Published 2010-09-01“…Le mouvement féministe a toujours suscité de fortes polémiques aux Etats-Unis et ses adversaires les plus virulents ont souvent été des femmes. L’antiféminisme féminin a été particulièrement vivace lors de la deuxième vague du féminisme, à partir des années 1970. …”
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587
Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
Published 2025-01-01“…Capsule, an essential virulence determinant, is a major cause of the enhanced pathogenicity of hvKP and thus represents an attractive drug target to prevent the devastating clinical outcomes caused by hvKP infection. …”
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588
Mycoketide: A CD1c-Presented Antigen with Important Implications in Mycobacterial Infection
Published 2012-01-01“…Mycobacterium tuberculosis and related mycobacteria species are unique in that the acid-fast bacilli possess a highly lipid-rich cell wall that not simply confers resistance to treatment with acid alcohol, but also controls their survival and virulence. It has recently been established that a fraction of the cell wall lipid components of mycobacteria can function as antigens targeted by the acquired immunity of the host. …”
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589
Inflammasomes, Autophagy, and Cell Death: The Trinity of Innate Host Defense against Intracellular Bacteria
Published 2019-01-01“…Various pathogens produce virulence factors to control inflammasomes, subvert autophagy, and modulate host cell death in order to evade host defense. …”
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590
E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature
Published 2017-01-01“…E. coli strains B2 and D produce cyclomodulin toxins as part of their virulence, which interferes with the cell cycle regulation, promoting chromosomal instability, and increasing susceptibility to cancer. …”
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591
Biofilm removal mediated by Salmonella phages from chicken-related sources
Published 2023-09-01“…Complete genome sequence analysis revealed that the genomes of phage CW1 is composed of 41763 bp with 58 open reading frames (ORFs) and a holin-endolysin system and it does not encode any virulence or lysogeny. A phage cocktail consisted of CW1 (with the broadest spectrum of 70.49 %) and CW11, M4 and M10 (with a high lytic activity of more than 67.11 %) was established. …”
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592
Pyoverdine, the Major Siderophore in Pseudomonas aeruginosa, Evades NGAL Recognition
Published 2012-01-01“…P. aeruginosa produces a major siderophore known as pyoverdine, found to be important for bacterial virulence and biofilm development. We report that pyoverdine did not bind to NGAL, as measured by tryptophan fluorescence quenching, while enterobactin bound to NGAL effectively causing a strong response. …”
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593
Leptospira and Inflammation
Published 2012-01-01“…The recent sequencing of the Leptospira genome has increased our knowledge about this pathogen. Although the virulence factors, molecular targets, mechanisms of inflammation, and signaling pathways triggered by leptospiral antigens have been studied, some questions are still unanswered. …”
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594
First detection of recombinant variant of African swine fever virus in the Russian Federation (brief communication)
Published 2024-09-01“…Zhao et al. reported on high virulence of the virus related variants as revealed by the challenge tests in domestic pigs. …”
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595
Novel mitochondrial-targeted alkyl chains act as fungal specific inhibitors of C. neoformans
Published 2025-02-01“…For example, C. neoformans possesses an Alternative Oxidase enzyme (Aox) that has been implicated in stress resistance and virulence that may represent a viable antifungal target. …”
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596
Helicobacter pylori CagA and IL-1β Promote the Epithelial-to-Mesenchymal Transition in a Nontransformed Epithelial Cell Model
Published 2016-01-01“…Gastric cancer is the third cause of cancer death worldwide and infection by Helicobacter pylori (H. pylori) is considered the most important risk factor, mainly by the activity of its virulence factor CagA. H. pylori/CagA-induced chronic inflammation triggers a series of gastric lesions of increased severity, starting with gastritis and ending with cancer. …”
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597
The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in <i>Klebsiella oxytoca</i>
Published 2025-01-01“…Our research highlights the pivotal role of OmpR, a key regulator within the EnvZ/OmpR two-component system, in controlling the virulence factors associated with <i>K. oxytoca</i>. …”
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598
Association of Lumican Gene with Susceptibility to Pathological Myopia in the Northern Han Ethnic Chinese
Published 2009-01-01“…Further studies are needed to confirm finally whether the two genes are the virulence genes of PM.…”
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599
Poly ADP-Ribosylation in a Plant Pathogenic Oomycete <i>Phytophthora infestans</i>: A Key Controller of Growth and Host Plant Colonisation
Published 2025-01-01“…Using dsRNA-mediated RNA silencing of the PiPARP2 gene and chemical (pharmacological) inhibition of PARP activity by 3-aminobenzamide (3AB) PARP inhibitor, we demonstrate the critical functional role of ADP-ribosylation in <i>Phytophthora</i> mycelium growth. Virulence test on detached leaves also suggests an important role of ADP-ribosylation in <i>Phytophthora</i> host plant colonisation and pathogenesis. …”
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600
A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro
Published 2013-01-01“…Lethal factor (LF) is a component of lethal toxin (LeTx), which is the major virulence of anthrax toxin. A murine IgG monoclonal antibody (mAb) against LF with blocking activity (coded LF8) was produced in a previous study. …”
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