Role of SarA in Staphylococcus aureus: A Virulence Target For Therapeutic Strategies by Yi He Kuai, Jodi Woan-Fei Law, Yong Sze Ong, Vengadesh Letchumanan, Learn-Han Lee, Loh Teng-Hern Tan

“… Methicillin-resistant Staphylococcus aureus (MRSA) infection gives rise to significant morbidity and carries a grave prognosis, resulting in the demise of approximately 21.8% of afflicted individuals on a yearly basis Staphylococcus aureus has the capability to induce a myriad of diverse diseases, a phenomenon attributed to its extensive array of virulence factors and formation of biofilms. The regulation of key virulence determinants, crucial for pathogenicity, is intricately controlled by the staphylococcal accessory regulatory (sarA) system. …”
Get full text

Virulence Factors Contributing to Pathogenicity of Candida tropicalis and Its Antifungal Susceptibility Profile by Sachin C. Deorukhkar, Santosh Saini, Stephen Mathew

“…Phospholipase enzyme was the major virulent factor produced by C. tropicalis isolates. …”
Get full text

Comparing traditional surveys and web-scraped data to understand the pigeon racing industry in Southern California by Maurice Pitesky, Malekah Isa, Charlene Rivera, Elise Streba, Joseph D. Gendreau

Subjects: Get full text

In silico sequence and structure prediction analysis of biomarker genes in Aeromonas sp. of Andaman and Nicobar Islands by Balakrishnan Meena, Lawrance Anburajan, Dilip Kumar Jha, Gopal Dharani

Subjects: Get full text

Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China by Hongli An, Xiamei Kang, Chenhu Huang, Chenghao Jia, Jiaqi Chen, Yingying Huang, Qianzhe Cao, Yan Li, Biao Tang, Min Yue

Subjects: Get full text

Candida auris: an emergent virulent and multidrug-resistant yeast associated with serious health implications by Hassan Yahaya, Hamza Sule

Get full text

Modulation of virulence and metabolic profiles in Klebsiella pneumoniae under indole-mediated stress response by Xueyao Fang, Yanhui Chen, Longhua Hu, Shumin Gu, Junqi Zhu, Yaping Hang, Xingwei Cao, Yanping Xiao, Hong Luo, Chuwen Zhao, Lianhua Xiao, Qiaoshi Zhong

Subjects: Get full text

Innovative Approaches to Suppressing Pseudomonas aeruginosa Growth and Virulence: Current Status and Future Directions by Sandip Patil, Xiaowen Chen, Feiqiu Wen

“…This review explores current and future innovative approaches to suppress its growth and virulence. We delve into the bacterium’s virulence factors, discussing existing strategies like antibiotics, bacteriophages, probiotics, and small-molecule inhibitors. …”
Get full text

Characterization of Potential Virulence Factors of Vibrio mimicus Isolated from Fishery Products and Water by M. F. Hernández-Robles, I. Natividad-Bonifacio, A. K. Álvarez-Contreras, J. J. Tercero-Alburo, E. I. Quiñones-Ramírez, C. Vázquez-Salinas

“…Seventy-five percent of V. mimicus strains showed cytopathic effect on Chinese hamster ovary (CHO) cells and destruction of the monolayer, and 100% of the strains were adherent on the HEp-2 cell line with an aggregative adherence pattern. The presence of virulence factors in V. mimicus strains obtained from fishery products suggests that another member of the Vibrio genus could represent a risk to the consumer due to production of different metabolites that allows it to subsist in the host.…”
Get full text

Virulence profile of carbapenem-resistant Klebsiella pneumoniae strains by an in vivo model of Galleria mellonella by María Guembe, Rama Hafian, Marta Díaz-Navarro, Andrés Visedo, Flavio De Maio, Fulvia Pimpinelli, Ilaria Cavallo, Mauro Truglio, Francesca Sivori, Enea Gino Di Domenico

“…ABSTRACT Klebsiella pneumoniae is a significant healthcare-associated pathogen, notable for its diverse virulence and antibiotic resistance profiles. This study aimed to characterize the genotypic and phenotypic diversity of K. pneumoniae isolates and evaluate their virulence using the Galleria mellonella model. …”
Get full text

Asymptomatic Periprosthetic Joint Infection of the Hip with High-Virulence Pathogens: Report of Two Cases by Ruben A. Mazzucchelli, Christoph Meier, Yvonne Achermann, Peter Wahl

“…Periprosthetic joint infection (PJI) may be a life-threatening condition, particularly when caused by pathogens with high virulence, capable of developing secondary bloodstream infection. …”
Get full text

H3K4 methylation regulates development, DNA repair, and virulence in Mucorales by Macario Osorio-Concepción, Carlos Lax, Damaris Lorenzo-Gutiérrez, José Tomás Cánovas-Márquez, Ghizlane Tahiri, Eusebio Navarro, Ulrike Binder, Francisco Esteban Nicolás, Victoriano Garre

“…On the other hand, histone methylation is a regulatory mechanism with pleiotropic effects, including the virulence of several pathogenic fungi. However, the role of epigenetic changes at the histone level never has been studied in Mucorales. …”
Get full text

Molecular detection of some virulence gene in Proteus mirabilis isolated from chicken and human by Aamer Y. Alchalaby, Balsam Y. Rasheed, Ammar M. Al-AAlim

“…In conclusion, our findings underscore the potential danger of virulence genes in poultry, a human staple food. This highlights the crucial need for caution in meat processing and the use of effective methods to prevent infection and sterilize meat before human consumption.…”
Get full text

A functional approach to analyze the genetic basis for differences in virulence of monkeypox virus clades by Patricia L. Earl, Jeffrey L. Americo, Sara Reynolds, Wei Xiao, Catherine Cotter, Bernard Moss

Subjects: Get full text

Molecular Detection of Virulence Factors in Salmonella serovars Isolated from Poultry and Human Samples by Kelly Johanna Lozano-Villegas, María Paula Herrera-Sánchez, Mónica Alexandra Beltrán-Martínez, Stefany Cárdenas-Moscoso, Iang Schroniltgen Rondón-Barragán

“…The presence of 24 virulence genes was evaluated using end-point PCR. …”
Get full text

Prevalence of Hyper virulence and Multidrug resistance Klebsiella pneumoniae isolates from UTI patients by Manar Abdul karim, Zainab Mohammed Alzubaidy, Khazal Dabua Wadi

“… Urinary tract infections (UTIs) are the most common bacterial infections and are often caused by Klebsiella pneumoniae. the results of detection of some virulence factors 30(13.6%)  isolates of K. pneumoniae showed that Hemolysin production was tested using sheep blood agar and it was found that all the 30 (100%) isolates of K. pneumonia not capable to hemolysis red blood. …”
Get full text

First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale by Ivan Tsers, Ekaterina Marenina, Azat Meshcherov, Olga Petrova, Olga Gogoleva, Alexander Tkachenko, Natalia Gogoleva, Yuri Gogolev, Evgenii Potapenko, Olga Muraeva, Mira Ponomareva, Viktor Korzun, Vladimir Gorshkov

Subjects: Get full text

Fungal Dimorphism and Virulence: Molecular Mechanisms for Temperature Adaptation, Immune Evasion, and In Vivo Survival by Gregory M. Gauthier

“…The conversion to yeast within healthy and immunocompromised mammalian hosts is essential for virulence. In the yeast phase, the thermally dimorphic fungi upregulate genes involved with subverting host immune defenses. …”
Get full text

Pectinolytic and Cellulolytic Enzymes Enhance Fusarium compactum Virulence on Tubercles Infection of Egyptian Broomrape by Olubukola O. Babalola

Get full text

A Fatal Case of Necrotizing Fasciitis Caused by a Highly Virulent Escherichia coli Strain by Sadjia Bekal, André Vincent, Alex Lin, Josée Harel, Jean-Charles Côté, Cécile Tremblay

“…DNA microarray revealed the presence of 20 virulence genes.…”
Get full text