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461
The prevalence and immune response to coinfection by avian haemosporidians in wild Eurasian blackbirds Turdus merula
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462
The Strategies Used by Animal Viruses to Antagonize Host Antiviral Innate Immunity: New Clues for Developing Live Attenuated Vaccines (LAVs)
Published 2025-01-01“…A summary of viral antagonistic mechanisms might provide a new theoretical basis for understanding the pathogenic mechanism of animal viruses and developing LAVs based on antagonistic mechanisms and viral virulence factors.…”
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463
Why Does Pnemococcus Kill?
Published 1999-01-01“…This paper reviews the major bacterial virulence factors and pathogenesis steps that characterize fatal pneumococcal pneumonia, with a focus on the inflammation that was observed from the initial infection to death in an experimental murine pneumonia model. …”
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464
An insight into the genome-wide analysis of bacterial defense mechanisms in a uropathogenic Morganella morganii isolate from Bangladesh.
Published 2025-01-01“…The beta-lactam resistance gene blaDHA was found using antimicrobial resistance (AMR) gene analysis across three databases. The virulence genes kdsA and cheY, which may be involved in chemotaxis and lipopolysaccharide production, were also available in the isolate, suggesting its high pathogenicity. …”
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465
Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model.
Published 2025-01-01“…We characterized the multiplication kinetics of rMACV-Chicava in African green monkey kidney epithelial Vero cells, followed by determining the virulence phenotype in outbred Hartley guinea pigs.…”
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466
Healthcare-associated infections caused by Candida spp. in critical infants: a look at environmental surfaces
Published 2025-01-01“…Biofilm was the only virulence factor produced by all nine isolates. Molecular analysis revealed high similarity between one environmental isolate and one clinical isolate of C. parapsilosis sensu stricto. …”
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467
Hypervirulent Klebsiella pneumoniae have better clinical outcomes than classical Klebsiella pneumoniae for lower respiratory tract infection patients
Published 2025-01-01“…All these strains underwent annotation for resistance and virulence factors, with 141 strains undergoing mouse infection experiments to assess their virulence. …”
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468
Microbiota Associated with Infections of the Jaws
Published 2012-01-01“…This paper discuss the possibility of spread of these infections and their clinical implications for dentistry, as well as their etiology and aspects related to microbial virulence and pathogenesis.…”
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469
Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages
Published 2002-01-01“…Here we review the present knowledge of the recently identified ASFV genes with special attention to those which affect viral virulence, host range, and pathogenesis by regulating viral-induced apoptotic mechanisms.…”
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470
Pathogenicity, Host Responses and Implications for Management of Enterohemorrhagic Escherichia coli O157:H7 Infection
Published 2013-01-01“…The present review focuses on the history, epidemiology and evolution of the pathogen; provides a mechanistic overview of major virulence factors (including Shiga toxins, locus of enterocyte effacement pathogenicity island and pO157 plasmid); discusses host immune responses to infection; considers available animal models; and provides an overview of current and potential future management considerations.…”
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471
The dangerous biology of pathogenic germs
Published 2024-09-01“…The convergence of biotechnologies with other disciplines, including computer science and Artificial Intelligence (AI), may make it possible to carry out dangerous genetic manipulations on pathogenic germs, as the gain-of-function experiments exacerbating virulence, as those carried out on myxoviruses and coronaviruses. …”
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472
Pulmonary Nocardiosis in an Immunocompetent Patient with Cystic Fibrosis
Published 2015-01-01“…Nocardia spp. are bacteria of low virulence that cause infection classically in immunocompromised hosts with the lungs as the primary site of infection in the majority of cases. …”
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473
Adherence of Helicobacter pylori to the Gastric Mucosa
Published 1997-01-01“…The mechanism by which H pylori causes disease has not yet been elucidated but adherence to the gastric mucosa is thought to be an important virulence determinant of the organism. What is known about adherence of H pylori to the gastric mucosa is summarized. …”
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474
Distribution of sasX, mupA, and qacA/B genes and determination of genetic relatedness of epidemic methicillin-resistant Staphylococcus aureus strains associated with bloodstream in...
Published 2025-01-01“…IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) exhibits diverse genotypes with varying virulence and resistance profiles, particularly in the context of bloodstream infections (BSI). …”
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475
Prevalence and Characterization of Streptococcus pyogenes Clinical Isolates from Different Hospitals and Clinics in Mansoura
Published 2020-01-01“…Different isolates were typed serotypically and genotypically by BOX-PCR. Different virulence factors were identified in S. pyogenes isolates. …”
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476
Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages
Published 2025-01-01“…Serine proteases emerge as important virulence factors in the Leishmania genus, as they participate in important processes involved in their infectivity, virulence, and survival. …”
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477
Flow cytometry sorting of cells infected with African swine fever virus
Published 2022-06-01“…The use of attenuated virus variants enables a thorough investigation of the factors influencing the virulence of African swine fever virus and the immune response to it. …”
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478
Global asymptotic properties of staged models with multiple progression pathways for infectious diseases
Published 2011-07-01“…For example, these models reflect cases when there is considerable difference in virulence, or when only a part of the infected individuals undergoes a treatment whereas the rest remains untreated. …”
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479
Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis
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480
High-quality draft genome and characterization of commercially potent probiotic strains
Published 2019-11-01“…The genomic analysis of all the strains confirmed the absence of genes encoding putative virulence factors, antibiotic resistance, and the plasmids.…”
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