Interesting Cytokine Profile Caused by Clinical Strains of Pseudomonas aeruginosa MDR Carrying the exoU Gene by Nallely S. Badillo-Larios, Edgar Alejandro Turrubiartes-Martínez, Esther Layseca-Espinosa, Roberto González-Amaro, Luis Fernando Pérez-González, Perla Niño-Moreno

“…Pseudomonas aeruginosa is an opportunistic pathogen in HAIs with two facets: the most studied is the high rate of antimicrobial resistance, and the less explored is the long list of virulence factors it possesses. This study aimed to characterize the virulence genes carried by strains as well as the profile of cytokines related to inflammation, according to the resistance profile presented. …”
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A Phage‐Based Approach to Identify Antivirulence Inhibitors of Bacterial Type IV Pili by Tori M. Shimozono, Nancy J. Vogelaar, Megan T. O'Hara, Zhaomin Yang

“…Antivirulants are small molecules designed to target virulence factors, thereby attenuating the virulence of infectious microbes. …”
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Comparative Genomics Reveals Pathogenicity-Related Loci in Shewanella algae by Jui-Hsing Wang, Guo-Cheng He, Yao-Ting Huang, Po-Yu Liu

“…However, there is scarce literature related to the understanding of the genetic background of virulence determinants in S. algae. In this study, we aim to determine the occurrence of common virulence genes in S. algae using whole-genome sequence and comparative genomic analysis. …”
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Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection. by Markus Schrettl, Elaine Bignell, Claudia Kragl, Yasmin Sabiha, Omar Loss, Martin Eisendle, Anja Wallner, Herbert N Arst, Ken Haynes, Hubertus Haas

“…Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for virulence, but non-existent in humans, presenting a rare opportunity to strategize therapeutically against this pathogen. …”
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Impacts of Pta-AckA pathway on CPS biosynthesis and type 3 fimbriae expression in Klebsiella pneumoniae by Tien-Huang Lin, Chen-Yu Wang, Chien-Chen Wu, Ching-Ting Lin

“…Understanding how K. pneumoniae regulates its virulence factors is crucial. Acetyl-phosphate (AcP) is essential for bacterial metabolism and can affect virulence factor expression. …”
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Leaf spot resistance in sweet and sour cherries by M. S. Lenivtseva, A. P. Kuznetsova, E. E. Radchenko

“…Five phenotypes of the fungus, differing in virulence to six cherry genotypes, were identified. …”
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Complex System Analysis of Blumeria graminis f.sp. tritici Isolates Collected in Central Hebei Province, China by Qingping Zhou, Lingli Li, Long Wang

“…Race 077 is the second dominant race. (2) The frequency of virulence genes VEra, V8, V1, V3c, and V3f in population toxicity frequency analysis was more than 70%, while the frequency of virulence genes V2, MID, V20, V21, V4b, and V4 was less than 16.7%, and 46% of virulence genes of powdery mildew were higher than 40%. …”
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Microevolution during Chronic Infection May Lead T. asahii to Coexist with the Host by Gen Ba, Xuelian Lv, Xin Yang, Wenling Wang, Junhong Ao, Rongya Yang

“…These results demonstrated that the microevolution during chronic infection could induce changes in immunogenicity, virulence, and transcriptome, which might lead T. asahii to coexist with the host.…”
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Pathogenesis of Helicobacter pylori-Related Gastroduodenal Diseases from Molecular Epidemiological Studies by Yoshio Yamaoka

“…H. pylori has a genome of approximately 1,600 genes; therefore, there might be other novel virulence factors. Because genome wide analyses using whole-genome sequencing technology give a broad view of the genome of H. pylori, we hope that next-generation sequencers will enable us to efficiently investigate novel virulence factors.…”
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Comparative Genomic Analysis of <i>Campylobacter</i> Plasmids Identified in Food Isolates by Yiping He, Gretchen Elizabeth Dykes, Siddhartha Kanrar, Yanhong Liu, Nereus W. Gunther, Katrina L. Counihan, Joe Lee, Joseph A. Capobianco

“…Plasmids, known as important mobile genetic elements, often carry genes for antibiotic resistance, virulence, and self-mobilization. They serve as the main vectors for transferring genetic material and spreading resistance and virulence among bacteria. …”
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Intraspecific variability of Puccinia triticina on hexaploid Triticum species and Aegilops trivialis by E. I. Gultyaeva, E. L. Shaydayuk, I. A. Kazartsev

“…To characterize the structure of the populations, virulence to Thatcher lines with leaf rust resistance genes (TcLr) and microsatellite markers may be used. …”
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Streptococcus halichoeri: Comparative Genomics of an Emerging Pathogen by Kirsi Aaltonen, Ravi Kant, Marjut Eklund, Mirja Raunio-Saarnisto, Lars Paulin, Olli Vapalahti, Thomas Grönthal, Merja Rantala, Tarja Sironen

“…A phylogenetic tree was constructed using the genes of the core genome. Virulence factors were assessed using the Virulence Factor Database (VFDB) concentrating on the previously confirmed streptococcal factors. …”
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Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors by Wen-Si Tan, Jodi Woan-Fei Law, Lydia Ngiik-Shiew Law, Vengadesh Letchumanan, Kok-Gan Chan

“…Also, many QS-controlled activities are involved in virulence and pathogenicity. Hence, understanding the details of quorum sensing mechanisms, its phenotype regulation (biofilm), and QS inhibitors (which attenuate virulence/pathogenicity) may open a new avenue for controlling bacterial infections. …”
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Alzheimer’s Disease and <i>Porphyromonas gingivalis</i>: Exploring the Links by Ivana Shawkatova, Vladimira Durmanova, Juraj Javor

“…While the exact pathways remain uncertain, studies detecting <i>P. gingivalis</i> virulence factors and its other components in AD-affected brains support their possible role in disease pathogenesis. …”
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Strain-limited biofilm regulation through the Brg1-Rme1 circuit in Candida albicans by Min-Ju Kim, Aaron P. Mitchell

“…ABSTRACT Prominent virulence traits of Candida albicans include its ability to produce filamentous hyphal cells and grow as a biofilm. …”
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Elegant and Innovative Recoding Strategies for Advancing Vaccine Development by François Meurens, Fanny Renois, Uladzimir Karniychuk

“…This method enhances vaccine safety and efficacy while minimizing the risk of reversion to virulence. Recoding enhances the frequency of CpG dinucleotides, which in turn activates immune responses and ensures a strong attenuation of the pathogens. …”
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Genomic characterization of foodborne Salmonella enterica and Escherichia coli isolates from Saboba district and Bolgatanga Municipality Ghana. by Gabriel Temitope Sunmonu, Frederick Adzitey, Erkison Ewomazino Odih, Boniface Awini Tibile, Rejoice Ekli, Martin Aduah, Anderson O Oaikhena, Olabisi C Akinlabi, Akebe Luther King Abia, Daniel Gyamfi Amoako, Iruka N Okeke

“…While strains belonging to virulence-associated lineages lacked key plasmid-encoded virulence plasmids, several plasmid replicons were detected in most of the E. coli (14/19) strains. …”
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Dual Control of Host Actin Polymerization by a Legionella Effector Pair by M. Pillon, C. Michard, N. Baïlo, J. Bougnon, K. Picq, O. Dubois, C. Andrea, L. Attaiech, V. Daubin, S. Jarraud, E. Kay, P. Doublet

“…Legionella pneumophila virulence relies on the injection of the largest known arsenal of bacterial proteins, over 300 Dot/Icm type 4 secretion system effectors, into the host cytosol. …”
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Identification of Staphylococcus aureus Causing Contamination in Raw Beef and Meat-Processing Environments in Ulaanbaatar, Mongolia by Amgalanzaya Dorjgochoo, Anujin Batbayar, Altansukh Tsend-Ayush, Bayarlakh Byambadorj, Sarantuya Jav, Munkhdelger Yandag

“…Resistance genes (mecA, mecC, vanA, and vanB) and virulence genes (sea, sed, tsst, eta, and etb) were detected via PCR. …”
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Computational protocol for analyzing whole-genome sequencing data from Staphylococcus aureus clinical isolates by Miquel Sánchez-Osuna, Ivan Erill, Oriol Gasch, Oscar Q. Pich

“…Summary: Analyzing whole-genome sequencing (WGS) data from bacterial isolates is pivotal for understanding virulence and predicting clinical outcomes through association studies. …”
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