Adapting to ulcerative colitis to try to live a ‘normal’ life: a qualitative study of patients’ experiences in the Midlands region of England by Rachel Cooney, Christel McMullan, Dmitri Nepogodiev, Laura Magill, Thomas D Pinkney, Jonathan M Mathers, Laura L Jones, Shri Pathmakanthan

“…Objective To provide a framework that is able to categorise whether patients are able to adapt to and lead a ‘normal’ life with ulcerative colitis (UC) and to detail the factors that influence this.Design Qualitative research study using in-depth semi-structured interviews.Setting Four clinical sites in the West and East Midlands regions of England.Participants 28 adult patients diagnosed with UC for years between 1 and 22.Results Medication was rarely sufficient for patients to adapt to UC and live as ‘normal’ a life as possible. Virtually all patients tested and adopted non-medical adaptation methods to improve physical and psychological well-being, to help them carry on working and to prevent embarrassment. …”
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A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice by Cristina Méndez-Vidal, Nereida Bravo-Gil, Javier Pérez-Florido, Irene Marcos-Luque, Raquel M. Fernández, José Luis Fernández-Rueda, María González-del Pozo, Marta Martín-Sánchez, Elena Fernández-Suárez, Marcela Mena, Rosario Carmona, Joaquín Dopazo, Salud Borrego, Guillermo Antiñolo

“…Methods Our approach involved customized probe designs, the generation of virtual panels and the development of a personalized medicine module (PMM) for variant prioritization. …”
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Observations of Unusual Daytime Range Spread F at Middle Latitude During the Afternoon Hours by Lehui Wei, Chunhua Jiang, Ting Lan, Wenxuan Wang, Hua Shen, Ercha Aa, Wengeng Huang, Jing Liu, Guobin Yang, Yaogai Hu, Zhengyu Zhao

“…Analysis of the iso‐frequency of ionospheric virtual height from ZHY ionosonde data during this event revealed the presence of wave‐like disturbances consistent with traveling ionosphere disturbances (TIDs)/atmospheric gravity waves (AGWs). …”
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Magnesium Oxide Nanoparticles Reinforced Electrospun Alginate-Based Nanofibrous Scaffolds with Improved Physical Properties by R. T. De Silva, M. M. M. G. P. G. Mantilaka, K. L. Goh, S. P. Ratnayake, G. A. J. Amaratunga, K. M. Nalin de Silva

“…SEM images revealed the spinnability of the complex composite nanofibrous scaffolds, showing randomly oriented, ultrafine, and virtually defects-free alginate-based/MgO nanofibrous scaffolds. …”
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Therapeutic strategies for tongue musculature: a systematic literature review by Andressa Colares da Costa Otavio, Arthur Cherem Netto Fernandes, Maria Eduarda Pollachinni Andrade, Brenda Barros Dias, Erissandra Gomes, Marco Aurélio Vaz

“…Research strategies Regional Portal of the Virtual Health Library for Latin America and the Caribbean, Embase, PubMed/MEDLINE, Scientific Electronic Library Online, SciVerse Scopus and Cochrane databases were consulted, with the descriptors "exercise therapy” OR “physiology” OR “musculoskeletal physiological phenomena” OR “digestive system and oral physiological phenomena” AND “speech therapy” OR “myofunctional therapy” OR “speech language pathology” AND “tongue”. …”
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First molecules to reactivate RASG12V GTPase activity by Aneta Wlodarczyk, Cezary Treda, Marcin Pacholczyk, Adrianna Rutkowska, Marta Wegierska, Amelia Kierasinska-Kalka, Katarzyna Wasiak, Damian Ciunowicz, Dagmara Grot, Pawel Glowacki, Ewelina Stoczynska-Fidelus, Piotr Rieske

“…Methods The compounds were initially identified through virtual screening, and their optimal binding conformation in the RAS SW-II pocket was determined using the flexible docking technique. …”
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Isolation of PCSK9-specific nanobodies from synthetic libraries using a combined protein selection strategy by Apisitt Thaiprayoon, Yodpong Chantarasorn, Worrapoj Oonanant, Anongnard Kasorn, Phoomintara Longsompurana, Satita Tapaneeyakorn, Pinpunya Riangrungroj, Fabien Loison, Andrew C. Kruse, Matthew P. DeLisa, Dujduan Waraho-Zhmayev

“…We anticipate that our strategy will be a valuable addition to the protein engineering toolkit, allowing development of Nbs or virtually any other synthetic binding protein for a wide range of applications.…”
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Structural bioinformatics for rational drug design by Soroush Mozaffari, Agnethe Moen, Che Yee Ng, Gerry A.F. Nicolaes, Kanin Wichapong

“…Key techniques, including structure- and ligand-based virtual screening, molecular dynamics simulations, and artificial intelligence–driven models are allowing researchers to explore vast chemical spaces, investigate molecular interactions, predict binding affinity, and optimize drug candidates with unprecedented accuracy and efficiency. …”
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Analysis of Digital Workflow in Implantology by Gustavo Vargas da Silva Salomão, Eliseo Pablo Chun, Renato dos Santos Panegaci, Fernando Toledo Santos

“…The patient had grade II mobility and external root resorption of tooth 11. After virtual planning, a surgical guide was fabricated by a CAD/CAM system, with immediate placement of a dental implant using the guided surgery technique. …”
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The use of nano-structured cellulose to improve plywood: A review by L.C. Lirya Silva, F.O. Lima, S.N. Monteiro, A.R.G. Azevedo, A.L. Christoforo, B.S. Ferreira, D. Goveia, C.I. de Campos

“…A subsequent search included the acronym “plywood” combined with terms such as “nanocellulose,” “cellulose nanocrystals,” and “cellulose nanofibrils.” The Virtual Operating System (VOS) Viewer was used to develop a graphical mapping. …”
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Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…For this purpose, the molecular modeling of the protein complexes and virtual screening of the potential inhibitors of FA DD has been performed. …”
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Social Entrepreneurship in Providing Employment: the Experience of Poland and Ukraine by Oleksandr Shpykuliak, Diana Shelenko, Ivan Balaniuk, Аnna Diuk, Hennadii Mazur, Sergiy Balaniuk, Andrii Boichuk

“…It was emphasized that classic social enterprises are virtually absent in Ukraine due to a lack of specific institutional and legal regulations. …”
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Digital mental health treatment implementation playbook: successful practices from implementation experiences in American healthcare organizations by David C. Mohr, David C. Mohr, Alexandra L. Silverman, Alexandra L. Silverman, Soo Jeong Youn, Soo Jeong Youn, Soo Jeong Youn, Patricia Areán, Andrew Bertagnolli, Jenna Carl, Tarolyn Carlton, Neha Chaudhary, David Cooper, Shelly DeVito, Stephanie Eaneff, Megan Flom, Valerie L. Forman-Hoffman, Leanna Fortunato, Karen Franchino, Andrea K. Graham, Heidi Greenberger, Jessica Hauflaire, Benjamin Kaveladze, Rachel Kornfield, Kaylee P. Kruzan, Eric Kuhn, Eric Kuhn, Carolyn MacIver, Frederick Muench, Regina Misch, Adrian Ortega, Lisa Palko, Derek Richards, Derek Richards, Louisa Salhi, Jonathan Schremp, Eva Szigethy, Eva Szigethy, Nathan Tatro, Bethany A. Teachman, Bethany A. Teachman, Trina Histon

“…To address this, the Society for Digital Mental Health established a DMHT Implementation Workgroup, with the goal of developing a DMHT Playbook that describes current best practices in DMHT implementation in American healthcare settings.MethodsThe workgroup was comprised of representatives from 7 healthcare systems and 10 DMHT companies that have conducted implementations, along with other stakeholders and technical experts. The workgroup met virtually to discuss implementation of effective DMHT implementation processes and inform the development of an interview guide, which was then administered to another 20 key opinion leaders with DMHT implementation experience. …”
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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

“…To address this challenge, digital twins have emerged as a promising approach, which have led to international initiatives aiming at clinical implementations. Digital twins are virtual representations of health and disease processes that can integrate real-time data and simulations to predict, prevent, and personalize treatments. …”
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MODELLING OF THE PREPARATION OF MASTERS OF PROFESSIONAL EDUCATION FOR ACTIVITIES IN THE INFORMATION AND DIGITAL ENVIRONMENT by Nataliia I. Lazarenko, Roman S. Gurevych, Alla P. Kobysia, Volodymyr M. Kobysia, Nadiia R. Opushko

“…The research demonstrates that it is necessary to include subjects aimed at developing digital competencies at a certain level in the content of their professional training in order to increase the effectiveness of teachers' activities in the modern conditions of informatization and digitalization of society and the formation of a virtual social and educational system. …”
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Bridging the Gap: Misaligned Perceptions of Urban Agriculture and Health Between Planning and Design Experts and Urban Farmers in Greater Lomé, Togo by Akuto Akpedze Konou, Kossiwa Zinsou-Klassou, Pablo Txomin Harpo De Roulet, Armel Firmin Kemajou Mbianda, Jérôme Chenal

“…Methodologically, 11 experts were selected in Greater Lomé and interviewed virtually via Zoom 5.6.6, and their audio files were anonymized, transcribed, and manually coded. …”
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High-Precision Sub-Wavelength Motion Compensation Technique for 3D Down-Looking Imaging Sonar Based on an Acoustic Calibration System by Jun Wang, Peihui Liang, Junqiang Song, Pan Xu, Yongming Hu, Peng Zhang, Kang Lou, Rongyao Ren, Wusheng Tang

“…The imaging scheme adopts a time-domain spatial beam-forming method with the Back Projection (BP) algorithm as the core, and the formation of a virtual plane array can effectively improve the along-track resolution. …”
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A comparative analysis of the health monitoring process using deep learning methods for brain tumour by N. Manjunathan, N. Gomathi

“…As technology improves, products for older people are developed in the health industry. Applications for virtual and remote interactions with patients are somewhat too simple to use. …”
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Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Apical Membrane Antigen 1 (AMA1) by Umashankar Vetrivel, Shalini Muralikumar, B Mahalakshmi, K Lily Therese, HN Madhavan, Mohamed Alameen, Indhuja Thirumudi

“…The proposed leads are the result of an exhaustive conformational search-based virtual screen with multilevel precision scoring of the docking affinities. …”
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Possibilities and limitations of applying ChatGPT in the educational process by Namesztovszk Zsolt B., Glušac Dragana R., Arsović Branka B., Kovacs Elvira I.

“…The article argues that ChatGPT has at least five main benefits, such as creating learning assessment, enhancing pedagogical practice, offering virtual personal tutoring, creating an essay or research article outline, and brainstorming ideas. …”
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