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3641
Swarm-Based Trajectory Generation and Optimization for Stress-Aligned 3D Printing
Published 2025-01-01“…The method utilizes swarming dynamics to simulate the motion of virtual agents along the stress field of a part under loading conditions. …”
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3642
An exploratory qualitative assessment of patient and clinician perspectives on patient-reported outcome measures and disease-modifying therapies in adults with spinal muscular atro...
Published 2025-01-01“…Methods: Semi-structured interviews were conducted virtually or in person with participants after they completed outcome measures at a routine clinic visit. …”
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3643
On Control of Reaching Movements for Musculo-Skeletal Redundant Arm Model
Published 2009-01-01“…The task-space feedback is extended to the ‘virtual spring-damper hypothesis’ based on the research by Arimoto et al. (2006) to reduce the muscle output forces and heterogeneity of convergence depending on the initial state and desired position. …”
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3644
Informed circular fields: a global reactive obstacle avoidance framework for robotic manipulators
Published 2025-01-01“…Furthermore, we extend the virtual agents framework introduced in Becker et al. (2021) to incorporate this global information, simulating multiple robot trajectories with varying parameter sets to enhance avoidance strategies. …”
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3645
Impact of Domain Knowledge and Multi-Modality on Intelligent Molecular Property Prediction: A Systematic Survey
Published 2024-09-01“…The precise prediction of molecular properties is essential for advancements in drug development, particularly in virtual screening and compound optimization. The recent introduction of numerous deep learningbased methods has shown remarkable potential in enhancing Molecular Property Prediction (MPP), especially improving accuracy and insights into molecular structures. …”
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3646
NeRF View Synthesis: Subjective Quality Assessment and Objective Metrics Evaluation
Published 2025-01-01“…This capability has significant advantages for applications such as virtual/augmented reality, 3D modelling, and content creation for the film and entertainment industry. …”
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3647
Identification of Epinastine as CD96/PVR inhibitor for cancer immunotherapy
Published 2025-01-01“…Results In this investigation, we employed MOE software to conduct virtual screening of small molecules from the FDA-approved drug library. …”
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3648
X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women
Published 2025-02-01“…Mechanistically, we found that USP11 facilitates the deubiquitination of the key transcription factor TPIT in functioning ACTH PitNETs, enhancing its protein stability and thereby promoting POMC transcription and ACTH secretion. Additionally, virtual screening identified Lomitapide and Nicergoline as potential inhibitors of USP11, reducing POMC expression and ACTH secretion. …”
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3649
Innovative models of healthcare delivery: an umbrella review of reviews
Published 2023-02-01“…Objective To undertake a synthesis of evidence-based research for seven innovative models of care to inform the development of new hospitals.Design Umbrella review.Setting Interventions delivered inside and outside of acute care settings.Participants Children and adults with one or more identified acute or chronic health conditions.Data sources PsycINFO, Ovid MEDLINE and CINAHL.Primary and secondary outcome measures Clinical indicators and mortality, healthcare utilisation, quality of life, self-management and self-care and patient knowledge.Results A total of 66 reviews were included, synthesising evidence from 1272 primary studies across the 7 models of care. Virtual care was the most common model studied, addressed by 47 (73%) of the reviews. …”
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3650
Negociações dialógicas nas identidades de cuidadoras de pessoas idosas: uma reflexão sobre um trabalho de quase
Published 2024-06-01“…Foram realizadas entrevistas abertas e de formato virtual, objetivando alcançar narrações autobiográficas sobre suas trajetórias de vida e ocupacionais. …”
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3651
Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1
Published 2025-01-01“…Domperidone was identified by pharmacophore-based virtual screening as a small molecule that can bind to both the viral envelope (E) and the nonstructural protein 1 (NS1) of DENV. …”
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3652
Smad1 Promotes Tumorigenicity and Chemoresistance of Glioblastoma by Sequestering p300 From p53
Published 2025-01-01“…Therefore, a small molecule is identified through virtual screening that specifically disrupts the Smad1‐p300 interaction, offering a promising strategy for inhibiting GBM and increasing chemosensitivity by inhibiting Smad1 acetylation and restoring p53 acetylation.…”
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3653
Digital Twin’s Anatomy: A Cross-Sector Framework With Healthcare Validation
Published 2025-01-01“…Digital twins (DT) in manufacturing, healthcare, and across different industrial domains are often over-simplified as solely a virtual representation of a physical object or service. …”
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3654
Autonomous sortie scheduling for carrier aircraft fleet under towing mode
Published 2025-01-01“…Specifically, eight processing procedures are abstracted, where tractors, preparing spots, catapults, and launching are virtualized as machines. By analyzing the constraints in sortie scheduling, a mixed-integer planning model is constructed. …”
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3655
Discovery and Characterization of Two Selective Inhibitors for a Mu-Class Glutathione S-Transferase of 25 kDa from <i>Taenia solium</i> Using Computational and Bioinformatics Tools
Published 2024-12-01“…Representative structures from these simulations and a putative binding site with low conservation relative to human GSTs, identified via the SILCS methodology, were employed for virtual screening through ensemble docking against a commercial compound library. …”
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3656
A double dissociation between semantic and spatial cognition in visual to default network pathways
Published 2025-01-01“…Participants learned virtual environments consisting of buildings populated with objects, drawn from either a single semantic category or multiple categories. …”
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3657
Improving Effectiveness of Safety Training at Construction Worksite Using 3D BIM Simulation
Published 2020-01-01“…This research will provide implications that an innovative method using the virtual reality is more effective than the conventional lecture method.…”
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3658
Dance Is an Accessible Physical Activity for People with Parkinson’s Disease
Published 2021-01-01“…To evaluate the outcomes of face-to-face, digital, and virtual modes of dancing for people living with Parkinson’s disease (PD). …”
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3659
Improved Performance and Voltage Stability of Islanded Inverters Using Single-Loop PI-Lead Controller
Published 2025-01-01“…Additionally, the control strategy reduces dependence on current measurements, except when dealing with inductive loads where virtual resistor-based active damping is necessary. …”
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3660
Digital competencies: perceptions of primary school teachers pursuing master’s degrees from eight African countries
Published 2022-08-01“…The teachers were master’s students in teacher training on virtual platforms. A mixed methodological perspective (quantitative-qualitative) was adopted and a questionnaire with closed and open-ended questions was applied. …”
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