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2601
Discovering broad-spectrum inhibitors for SARS-CoV-2 variants: a cheminformatics and biophysical approach targeting the main protease
Published 2025-02-01“…Therefore, a thorough receptor-based virtual screening study was conducted to screen different natural and synthetic drug libraries, such as the Asinex Antiviral, Seaweed Metabolite Database, Medicinal Fungi Secondary Metabolite and Therapeutics Library, and Comprehensive Marine Natural Products Database comprising 6,827, 1,191, 1,830, and 45,000 compounds, respectively, against the main protease enzyme of SARS-CoV-2. …”
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2602
Do discurso de ódio homofóbico à resistência lgbtqia+: uma análise das mensagens publicadas nas redes sociais
Published 2020-11-01“…Desse modo, esperamos que essa reflexão contribua para uma mudança de comportamento entre os sujeitos, levando-os a assumirem uma postura mais empática, respeitando as diferentes expressões de gênero e orientações afetivossexuais, nos variados espaços de convivência social, virtual ou físico. …”
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2603
Species specificity and specificity diversity (SSD) framework: a novel method for detecting the unique and enriched species associated with disease by leveraging the microbiome het...
Published 2024-12-01“…This prompts many researchers to believe that the promise should be downward to species or even strain level—effectively and efficiently identifying unique or enriched species in diseased microbiomes with statistical rigor. Nevertheless, virtually, all species-level approaches such as differential abundance and differential network analysis methods exclusively rely on species abundances without considering species distribution information, while it can be said that distribution is equally, if not more, important than abundance in shaping the spatiotemporal heterogeneity of community compositions. …”
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2604
Optimal Non-Pharmacological Interventions for Reducing Problematic Internet Use in Youth: A Systematic Review and Bayesian Network Meta-Analysis
Published 2025-01-01“…We identified 90 RCTs including 15 different NPIs (5986 participants), namely sports intervention (SI), electroencephalogram biological feedback (EBF), reality therapy (RT), positive psychology therapy (PPT), sandplay therapy (ST), educational intervention (EI), compound psychotherapy (CPT), electroacupuncture therapy (AT), group counseling (GC), family therapy (FT), electrotherapy (ELT), craving behavior intervention (CBI), virtual reality therapy (VRT), cognitive behavior therapy (CBT), and mindfulness therapy (MT). …”
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2605
Overview of styles, content, learning effects and attitudes of students towards digitally enhanced physiotherapy education – a scoping review
Published 2025-02-01“…Synchronous and asynchronous methods were used, with varying success across theoretical and practical courses. Gamification and virtual reality emerged as promising tools for enhancing engagement and learning outcomes. …”
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2606
SYSTEM ANALYSIS AND DESIGN OF THE GAME «SHOOTING SIMULATION IN A SHOOTING RANGE»
Published 2024-12-01“…Thus, the presented development serves as an example of the successful application of modern technologies in the field of interactive entertainment and demonstrates the prospects for developing such projects in the context of the growing popularity of virtual games and simulators.…”
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2607
Iranian Pediatric COVID-19 Epidemiology and Clinical Characteristics
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2608
Residual organochlorine pesticide contaminants profile in fish and sediment from a dam
Published 2021-04-01“…Indigenes rely on the dam for drinking water and irrigation of their farmlands as well as for fish and other aquatic delicacies. Virtually there exists no study on the residual levels of organochlorine or other pesticide contaminants in the dam despite its susceptibility to pesticide contamination. …”
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2609
A biomechanical comparison of posterior malleolar fracture fixation using screws and locking plates in Trimalleolar fractures: a finite element study
Published 2025-02-01“…The medial, lateral, and posterior malleoli were segmented using three virtual planes to create a trimalleolar fracture model, with the posterior malleolar fracture fragment comprising approximately 30% of the articular surface. …”
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2610
The impact of climate change on the development of water resources
Published 2024-07-01“…However, it is impossible to determine this change's direction definitively until the model results are assessed under various scenarios. Therefore, the virtual future of socio-hydrologic assessment and better integration of stakeholders is needed to understand the dynamics in the basin for sustainable water resource development and management.…”
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2611
Screening, diagnosis, treatment and outcomes of developmental dysplasia of the hip in Brazilian population: a scoping review
Published 2025-02-01“…Objective This study aims to map the literature on screening, diagnosis, treatment and outcomes of developmental dysplasia of the hip (DDH) in the Brazilian population aged 0–18 years, to describe regional variations in its presentation and management.Design Scoping review.Data sources PubMed/MEDLINE, Web of Science, Scopus, “Biblioteca Virtual em Saúde” and “Biblioteca Digital Brasileira de Teses e Dissertações”. …”
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2612
Time-Varying Total Stiffness Matrix of a Rigid Machine Spindle-Angular Contact Ball Bearings Assembly: Theory and Analytical/Experimental Verifications
Published 2011-01-01“…The bearing dynamic stiffness/damping marix is derived in terms of the bearing motions (displacements/rotations) and then the principal of virtual work is used to transfer it from the bearing location to the rotor mass center to obtain the total dynamic stiffness/damping matrix. …”
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2613
Diabetes mellitus na gestação como fator de risco para complicações neonatais
Published 2025-02-01“…Foram utilizadas as bases Biblioteca Virtual em Saúde (BVS), LILACS, SciELO e PubMed. Após o processo de análise, foram selecionados 12 estudos sobre os impactos da abordagem diagnóstica e terapêutica do DMG na saúde do recém-nascido. …”
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2614
Information Technology Framework for Pharmaceutical Supply Chain Demand Management: a Brazilian Case Study
Published 2016-01-01“…One spec ific for infrastructure, to enable data and systems interoperability among SC participants, considering a virtualized infrastructure environment (Cloud); 2. …”
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2615
Cs+ Adsorption and Pyrolytic Volume Reduction Performance of KR-01 Mixed Ion Exchange Resin
Published 2025-02-01“…After pyrolysis at 900 ℃, the residual amount of resin is around 48.970%, and Cs+ is virtually undetectable in the pyrolytic volatile gases, achieving efficient volume reduction and stable disposal of the waste resin. …”
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2616
Desarrollo de habilidades socioemocionales en la formación de educadores en la sociedad actual
Published 2025-02-01“…El proceso involucró la participación activa del docente, quien asumió el rol inicial en la intervención mediante la entrega de instrucciones y guías para el desarrollo de las habilidades socioemocionales sobre ética y educación en sus diversos contextos, realizada de manera virtual en un centro de educación superior de Chile. …”
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2617
Nueva narrativa digital para la simulación del control en el género aventura gráfica: el caso The Walking Dead
Published 2022-08-01“…Se distinguen 3 tipos de jugabilidades: 1) la exploración e interacción libre del mundo virtual que ofrecen la inmersión en el videojuego; 2) los diálogos y acciones elegidos por el jugador que simulan el control narrativo; 3) las cinemáticas no interactivas que dan mayor profundidad a la historia mientras desvelan los efectos de las elecciones. …”
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2618
Value of dual-energy CT quantitative parameters combined with clinical features in diagnosis of stages T2 and T3 colorectal cancer
Published 2025-01-01“…Results Univariate analysis showed that carcinoembryonic antigen (CEA), N stage, tumor location, tumor longest diameter (LD), CT value of virtual noncontrast (CT-VNC), fat fraction, electron density (Rho) and dual energy index (DEI) were significantly different between the T2 and T3 groups (P<0.05). …”
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2619
Quetiapine-related weight loss: Report of a rare adverse effect
Published 2018-07-01“…Though weight gain could occur in virtually every antipsychotic, weight loss has been recorded in very few cases. …”
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2620
Research on Operation Characteristics and Safety Risk Forecast of Bus Driven by Multisource Forewarning Data
Published 2020-01-01“…Finally, model checking and virtual simulation experiments are carried out. The result of the research shows that the driver’s fatigue risk during the period of 7 : 00-8 : 00 am is much higher than other periods. …”
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