Antigen Presenting Cells and Stromal Cells Trigger Human Natural Killer Lymphocytes to Autoreactivity: Evidence for the Involvement of Natural Cytotoxicity Receptors (NCR) and NKG2... by Alessandro Poggi, Maria Raffaella Zocchi

“…Nevertheless, NK cells kill self cells expressing low levels or lacking HLA-I, as it may occur during viral infections (missing-self hypothesis). Herein, we show that human NK cells can be activated upon binding with self antigen presenting cells or stromal cells despite the expression of HLA-I. …”
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Early-Onset Chronic Inflammatory Disease Associated with Maternal Microchimerism by Tomoaki Ishikawa, Yoshihiko Sakurai, Tomohiro Takeda, Hiroshi Suzuki

“…Serum levels of IL-6 and B-cell activating factor were elevated. Viral infections were not identified. Although HLA typing revealed no noninherited maternal antigens in lymphocytes, female cells were demonstrated in the patient’s skin and lymph nodes, suggesting that maternal microchimerism might be involved in the pathogenesis of fever without source in infants.…”
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Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation by Xihang Chen, Yunfan He, Feng Lu

“…Impairment of this process has been implicated in various diseases, in the pathogenic response to bacterial and viral infections, and in aging. Pluripotent stem cells, with their ability to self-replicate and to give rise to any specialized cell type, are very valuable resources for cell-based medical therapies and open a number of promising avenues for studying human development and disease. …”
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Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation by Adam Aguirre, Carola J. Maturana, Paloma A. Harcha, Juan C. Sáez

“…During pregnancy, the previous responses promoted by viral infections and other proinflammatory conditions are common and might predispose the offspring to develop psychiatric disorders and neurological diseases. …”
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Analysis of Fractional Order Mathematical Model of Hematopoietic Stem Cell Gene-Based Therapy by Mohammad Imam Utoyo, Windarto, Aminatus Sa’adah

“…A mathematical model approach could be used to predict the dynamics of HSC gene-based therapy of viral infections. In this paper, we present a fractional mathematical model of HSC gene-based therapy with the fractional order derivative α∈0,1. …”
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Fatal acute liver failure following norovirus gastroenteritis in a child: A case report by Rabab Taha, Noura Elazhary, Sarah Alqhtani, Walaa Almansouri

“…Other potential causes including drugs and other possible viral infections were ruled out, only norovirus was isolated from his stool. …”
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A Case Series of Psychological Stress Evaluation as a Risk Factor for Oral Lichen Planus by Irna Sufiawati, Ani Megawati, Muhammad Al Farisyi, I. Nyoman Gede Juwita Putra

“…Suggested predisposing factors for the development of OLP include genetic factors, viral infections, psychological stress, trauma, drug intake, and some systemic diseases. …”
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Toll-Like Receptors in Natural Killer Cells and Their Application for Immunotherapy by Ji-Yoon Noh, Suk Ran Yoon, Tae-Don Kim, Inpyo Choi, Haiyoung Jung

“…TLRs in NK cells induce the innate immune responses against bacterial and viral infections via inducing NK cytotoxicity and cytokine production. …”
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Psychosis in a 15-Year-Old Female with Herpes Simplex Encephalitis in a Background of Mannose-Binding Lecithin Deficiency by Kenneth Asogwa, Kwame Buabeng, Amarjit Kaur

“…Historically, psychotic disorder has been associated with viral infection. Herpes simplex infections and Epstein-Barr virus (EBV) among other viral infections have been implicated in psychotic disorder. …”
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Molecular Modeling and Simulation Analysis of Antimicrobial Photodynamic Therapy Potential for Control of COVID-19 by Maryam Pourhajibagher

“…Since antiviral photodynamic therapy (aPDT) has been described as a new method for inhibiting viral infections, it is important to evaluate whether it can be used as a photoactivated disinfectant to control COVID-19. …”
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Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine by Sajib Chakraborty, Taibur Rahman, Rajib Chakravorty

“…Although the exact mechanism by which CTL epitopes and the restricting HLA alleles mediate their action towards slow disease progression is still not clear, the important CTL restricted epitopes for controlling viral infections can be utilized in future vaccine design. …”
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Targeting Herpetic Keratitis by Gene Therapy by Hossein Mostafa Elbadawy, Marine Gailledrat, Carole Desseaux, Diego Ponzin, Stefano Ferrari

“…By November 2012, approximately 28 clinical trials were approved to assess novel gene therapy agents. Viral infections such as herpetic keratitis caused by herpes simplex virus 1 (HSV-1) can cause serious complications that may lead to blindness. …”
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Identification and Characterization of a Novel Rat MAVS Variant Modulating NFκB Signaling by Ihsan Nalkiran, Hatice Sevim Nalkiran

“…The innate immune response serves as the primary defense against viral infections, with the recognition of viral nucleic acids by pattern recognition receptors (PRRs) initiating antiviral responses. …”
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Characterization of Esocid Herpesvirus 1 (EsHV1) from Europe by Mikael Leijon, Charlotte Axén, Fereshteh Banihashem, Tobias Lilja, Petter Tibblin, Björn David Persson

“…In addition to the EsHV1 infected pike, we also observed that 11.1% of the pike were affected by lymphosarcoma, a hyperplasia-disease caused by retroviruses. In conclusion, viral infections in pike are relatively common and likely have consequences for the local population dynamics.…”
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Severe Aplastic Anemia following Acute Hepatitis from Toxic Liver Injury: Literature Review and Case Report of a Successful Outcome by Kamran Qureshi, Usman Sarwar, Hicham Khallafi

“…HAAA is described to occur with AH caused by viral infections and also with idiopathic cases of AH and no clear etiology of liver injury. …”
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Association of anti-phospholipid antibodies and hepatitis B virus infection in Najaf Governorate by Ameer Mohammed Kadhim, Hawraa Ameer Mubark, Dhefaf Hameed Al-Mudhafar, Zainab Hayder Abdulmajeed

“…Hepatitis B virus (HBV) is one of the most prevalent viral infections in the world and has been connected to a number of autoimmune illnesses. …”
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Sensitive and label-free fluorescent microRNA detection via catalytic DNAzyme assembly initiated primer exchange reaction by Heng Wang, Yi Sun

“…MicroRNAs (miRNAs) have an intricate connection to the development of human diseases, such as malignancies, diabetes, and viral infections; therefore, their rapid and precise identification is critical in disease diagnosis and treatment. …”
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Clinical Profile of Dengue Fever in Children: A Study from Southern Odisha, India by Shubhankar Mishra, Ramya Ramanathan, Sunil Kumar Agarwalla

“…The majority of dengue viral infections are self-limiting, but complications may cause high morbidity and mortality. …”
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Enhancing Monkeypox Detection through Data Analytics: A Comparative Study of Machine and Deep Learning Techniques by Kinjal A. Patel, Asadi Srinivasulu, Kuntesh Jani, Goddindla Sreenivasulu

“…Monkeypox detection is a challenging task due to the disease's resemblance to other viral infections such as smallpox and chickenpox. This paper presents a comprehensive study that investigates the efficacy of machine and deep learning techniques in detecting monkeypox. …”
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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

“…This study leverages protein engineering to enhance ACE2’s therapeutic potential for treating conditions such as respiratory viral infections, acute respiratory distress syndrome, and diabetes. …”
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