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541
Transcriptome-wide dynamics of m6A methylation in ISKNV and Siniperca chuatsi cells infected with ISKNV
Published 2025-01-01“…N6-methyladenosine (m6A), recognized as a common epigenetic modification of RNA, plays an important regulatory role during viral infection. However, the impact of m6A RNA methylation on the pathogenicity of ISKNV remains unexplored. …”
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542
Blood Genomics Identifies Three Subtypes of Systemic Lupus Erythematosus: “IFN-High,” “NE-High,” and “Mixed”
Published 2021-01-01“…We speculated that IFN-high might be due to the overproduction of interferons (IFNs) caused by viral infection, leading to the formation of autoantibodies. …”
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543
Recurrent Pneumothorax in a Critically Ill Ventilated COVID-19 Patient
Published 2020-01-01“…We present this case of a young woman with SARS-CoV-2 viral infection resulting in coronavirus 2019 (COVID-19) lung disease complicated by a complex hydropneumothorax, recurrent pneumothorax, and pneumatoceles. …”
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544
Therapeutic potential of the neutralizing monoclonal antibody 45G3 against encephalomyocarditis virus
Published 2025-01-01“…Additionally, posttreatment analysis revealed reduced tissue damage and a markedly decreased inflammatory response in the brain, indicating that the 45G3 antibody effectively blocked viral infection, thereby mitigating tissue damage and enhancing survival. …”
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545
Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus
Published 2025-01-01“…In summary, our findings demonstrate that viral infection rapidly depletes neuronal progenitor cells and causes aberrant migration of the remaining ones, potentially contributing to hyperexcitability. …”
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546
Evaluation of Yellow Fever Virus Infection in <i>Aedes aegypti</i> Mosquitoes from Pakistan with Distinct Knockdown Resistance Genotypes
Published 2024-12-01“…Two kdr genotypes (II + CC and TI + FC) were identified, with no significant differences in viral infection or dissemination rates. Conclusions: The <i>Ae</i>. …”
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547
A20 as a Potential Therapeutic Target for COVID‐19
Published 2025-01-01“…It effectively suppresses the immune damage and inflammatory storm caused by viral infection. Conclusions Understanding the relationship between A20‐regulated signaling pathways and pathological processes of COVID‐19 can provide insight into potential targets for intervention. …”
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548
Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir.
Published 2024-04-01“…Taken together, these data highlight the heterogeneity of the RCVR between RMs, the stochastic establishment of the very early RCVR, and the saturability of the RCVR prior to peak viral infection.…”
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549
Evaluation and diagnostic approach in patient with Perrault Syndrome
Published 2024-07-01“…At age 9, she was diagnosed with a viral infection by an ENT specialist due to bilateral hearing loss, leading to emotional disturbances. …”
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550
Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2
Published 2025-01-01“…Our findings complement previous research identifying specific genetic variants that influence COVID-19 susceptibility and severity, emphasizing the complex interplay between host genetics and viral infection outcomes. Our results are consistent with a potential causative role of IGH regulatory regions (e.g. …”
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551
HCV and HBV genotypes: vital in the progression of HCV/ HBV co-infection
Published 2025-01-01“…To determine the liver damage due to viral infection levels of ALT, ALP, and total bilirubin were also determined. …”
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552
Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity
Published 2025-01-01“…The contribution of extracellular ACBP to immunometabolic responses during viral infection should be further studied.…”
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553
Genotype-driven sensitivity of mice to tick-borne encephalitis virus correlates with differential host responses in peripheral macrophages and brain
Published 2025-01-01“…Abstract Background Tick-borne encephalitis (TBE) is the most common tick-borne viral infection in Eurasia. Outcomes range from asymptomatic infection to fatal encephalitis, with host genetics likely playing a role. …”
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554
A study of the clinico-demographical profile of different dengue serotypes circulating in a Southern district of West Bengal, India
Published 2025-02-01“…Background: Dengue virus (DENV) which is endemic in many tropical and subtropical areas around the world has four serotypes (DENV1, DENV2, DENV3and DENV4), this viral infection can either cause mild febrile illness Dengue fever or severe, such as Dengue hemorrhagic fever or Dengue Shock Syndrome. …”
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555
Monitoring of hepatitis E virus infection and replication by functional tagging of the ORF2 protein
Published 2025-03-01“…Proof-of-concept experiments revealed that convenient and quantitative monitoring of viral infection and replication is possible with this system, allowing for the evaluation of antiviral drugs and neutralizing antibodies.…”
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556
Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors
Published 2025-01-01“…Abstract The monkeypox virus (MPXV), which is a member of the Orthopoxvirus genus in the class Poxviridae, is the causative agent of the zoonotic viral infection MPXV. The disease is similar to smallpox, but it is usually less dangerous. …”
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557
A new pathogen pattern of acute respiratory tract infections in primary care after COVID-19 pandemic: a multi-center study in southern China
Published 2025-01-01“…Overall, patients with viral infection or viral-bacterial co-infection had more clinical symptoms, and patients with bacterial infection had higher inflammatory indicators. …”
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558
Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids
Published 2025-01-01“…Abstract Background Severe and critical COVID-19 is characterized by pulmonary viral infection with SARS-CoV-2 resulting in local and systemic inflammation. …”
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559
Increases in the susceptibility of human endometrial CD4+ T cells to HIV-1 infection post-menopause are not dependent on greater viral receptor expression frequency
Published 2025-01-01“…Treatment of EM derived CD4+ T cells with 17β-estradiol (E2) prior to viral infection, reduced infection frequency independent of changes in either CCR5 or α4β7 expression frequency. …”
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560
The Epidemiological Characteristics of Coronavirus Disease (COVID-19) in Halabja Province/Kurdistan –Iraq
Published 2022-01-01“…The new highly transmitted pathogenic viral infection started from Wuhan, China at the end of 2019. …”
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