Prediction of influenza A virus-human protein-protein interactions using XGBoost with continuous and discontinuous amino acids information by Binghua Li, Xin Li, Xiaoyu Li, Li Wang, Jun Lu, Jia Wang

“…Identifying protein-protein interactions (PPIs) between IAV and human proteins is beneficial for understanding the mechanism of viral infection and designing antiviral drugs. In this article, we developed a sequence-based machine learning method for predicting PPI. …”
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Serum levels of the Parkinson's disease-linked protein Parkin are specifically elevated in COVID-19 by Nadezhda G. Gumanova, Natalya L. Bogdanova, Alexander Yu. Gorshkov

“…Specificity versus another viral infection was tested in the serum samples with positive or negative status of IgG-AdV antibodies. …”
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Spatiotemporal Distributions of Sheep and Goat Pox Disease Outbreaks in the Period 2013–2019 in Eastern Amhara Region, Ethiopia by Sileshi Aregahagn, Belege Tadesse, Bethelihem Tegegne, Yalelet Worku, Seid Mohammed

“…Sheep and goat pox is highly contagious viral infection of sheep and goats caused by the genus Capripox virus. …”
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Change in exacerbation rate of COPD patients before and after COVID-19 infection by Joon Young Choi, Kyung Joo Kim, Chin Kook Rhee

“…Abstract The COVID-19 pandemic has profoundly affected global health system, significantly altering not only the acute management of viral infection, but also management strategies for chronic diseases. …”
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Long-term Air Pollution Exposure Impact on COVID-19 Morbidity in China by Yihan Wu, Qingming Zhan, Qunshan Zhao

“…Abstract Although previous studies have proved the association between air pollution and respiratory viral infection, given the relatively short history of human infection with the severe acute respiratory syndrome coronavirus (SARS-CoV-2), the linkage between long-term air pollution exposure and the morbidity of 2019 novel coronavirus (COVID-19) pneumonia remains poorly understood. …”
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Recurrent Herpes Zoster Ophthalmicus Preceded by Anabolic Steroids and High-Dose L-Arginine by Stephen A. LoBue, Adam Goldman, Richard A. Giovane, Stacy M. Carlson, Michael Bivona, Sinan Albear, Thomas D. LoBue

“…Anabolic steroids have also been demonstrated by various studies to negatively affect cell-mediated immunity necessary to prevent viral infection. Thus, it is possible that anabolic steroids in conjunction with increased L-arginine intake may have precipitated a recurrent HZO in a previously healthy, immunocompetent individual.…”
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Urinary Lactate Dehydrogenase Activity and Its Isozyme Patterns in Kawasaki Disease by Yoichi Kawamura, Seiichiro Takeshita, Takashi Kanai, Mari Takizawa, Yusuke Yoshida, Yuki Tsujita, Shigeaki Nonoyama

“…Total U-LDH activity and its isozymes (U-LDH1-5) levels were compared among 120 patients with KD, 18 patients with viral infection (VI), and 43 patients with upper urinary tract infection (UTI) and additionally compared between intravenous immunoglobulin (IVIG) responders (n=89) and nonresponders (n=31) with KD. …”
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Release of Type 2 Cytokines by Epithelial Cells of Nasal Polyps by Monica Boita, Caterina Bucca, Giuseppe Riva, Enrico Heffler, Giovanni Rolla

“…CRSwNP epithelial cells release TSLP and IL-25 when stimulated by poly(I:C) but not by DP or AF, suggesting that viral infection may contribute to maintain and amplify the T2 immune response seen in CRSwNP.…”
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Transcription factor KLF2 is associated with the dysfunctional status of NK cells and the prognosis of pediatric B-ALL patients by Fang Wu, Huimin Xu, Benshan Zhang

“…BackgroundNatural killer cells, an important component of the innate immune system, can directly recognize and lyse virally infected or transformed cells. However, NK cells fail to restrain the growth of malignancies, such as B-cell acute lymphoblastic leukemia (B-ALL). …”
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The viral and cellular microRNA targetome in lymphoblastoid cell lines. by Rebecca L Skalsky, David L Corcoran, Eva Gottwein, Christopher L Frank, Dong Kang, Markus Hafner, Jeffrey D Nusbaum, Regina Feederle, Henri-Jacques Delecluse, Micah A Luftig, Thomas Tuschl, Uwe Ohler, Bryan R Cullen

“…Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. …”
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Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department by John E. Schneider, Jonathan Romanowsky, Philipp Schuetz, Ivana Stojanovic, Henry K. Cheng, Oliver Liesenfeld, Ljubomir Buturovic, Timothy E. Sweeney

“…., assesses the likelihood of a bacterial infection, the likelihood of a viral infection, and the severity of the condition. …”
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Clinical Evaluation of Acute Pancreatitis Caused by SARS-CoV-2 Virus Infection by Hulya Vatansev, Mehmet Aykut Yıldırım, Serkan Kuccukturk, Mehmet Ali Karaselek, Cengiz Kadiyoran

“…We aimed to present acute pancreatitis (AP) cases caused by SARS-CoV-2 viral infection. Methods. The study was conducted retrospectively between April 2020 and June 2020 in Necmettin Erbakan University Meram, Medical Faculty Hospital, and 150 hospitalized patients diagnosed with COVID-19 were included. …”
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Differential gene expression during recall of behaviorally conditioned immune enhancement in rats: a pilot study [version 3; peer review: 1 approved, 3 approved with reservations] by Marcus Picard-Mareau, Markus Rueckels

“…Methods Rats were conditioned with camphor smell and poly I:C injection, mimicking a viral infection. Following stimulus re-exposure, animals were sacrificed at different time points, and neural tissues along the HPA axis was analyzed with a rat genome array together with plasma protein using Luminex analysis. …”
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EFFECTS OF MODERATELY VIRULENT AFRICAN SWINE FEVER VIRUS ON INTERLEUKIN-10 PRODUCTION by A. S. Pershin, I. V. Shevchenko, A. S. Igolkin, Ye. V. Aronova, N. N. Vlasova

“…Cytokines are important factors for various viral infection pathologies. The virulence of ASFV isolates may depend on the capacity to regulate cytokine expression by macrophages. …”
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Mpox gastrointestinal manifestations: a systematic review by Rahul Ramakrishnan, Atira Shenoy, Ranganathan Madhavan, Damon Meyer

“…Introduction Mpox is a viral infection caused by the monkeypox virus, a member of the Poxviridae family and Orthopoxvirus genus. …”
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Nebulised 3% hypertonic saline versus 0.9% saline for treating patients hospitalised with acute bronchiolitis: protocol for a randomised, double-blind, multicentre trial by Sara Szupieńko, Aleksandra Buczek, Henryk Szymański

“…Introduction Bronchiolitis is an acute viral infection of the lower respiratory tract. It is most commonly caused by respiratory syncytial virus. …”
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Construction of a Vero cell line expression human KREMEN1 for the development of CVA6 vaccines by Dongqing Zhang, Yuxiang Zou, Jiaying Wu, Longfa Xu, Zhifeng Ke, Yuanyuan Wu, Zhenhong Zhou, Mujin Fang, Ling Chen, Henggang Xu, Jianping Chu, Ningshao Xia, Rui Zhu, Tong Cheng

“…The expression level of virus-specific receptors on the cell membrane significantly influences viral infection. Here, a Vero cell line with stable over-expressing of KREMEN1 (KRM1), a crucial receptor for CVA6, was constructed using the lentivirus system. …”
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Asymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks by Fiona Greco, Hannah M. Ravenswater, Francisco Ruiz-Raya, Chiara D’Avino, Mark A. Newell, Josie Hewitt, Erin Taylor, Ella Benninghaus, Francis Daunt, Gidona Goodman, David Steel, Jenny Park, Emma Philip, Saumya S. Thomas, Marek J. Slomka, Marco Falchieri, Scott M. Reid, Joe James, Ashley C. Banyard, Sarah J. Burthe, Emma J. A. Cunningham

“…We therefore tested for antibodies, indicative of previous exposure and recovery, and for active viral infection in apparently healthy individuals (n = 350) across five co-occurring seabird species on the Isle of May, Scotland, during 2023, following H5N1 HPAIV associated mortality in the preceding summer. …”
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Multiscale modelling of hepatitis B virus at cell level of organization by Huguette Laure Wamba Makeng, Ivric Valaire Yatat-Djeumen, Bothwell Maregere, Rendani Netshikweta, Jean Jules Tewa, Winston Garira

“…The between-cell scale is linked to the within-cell scale by a once off inflow of initial viral infective inoculum dose from the between-cell scale to the within-cell scale through the process of infection; the within-cell scale is linked to the between-cell scale through the outflow of the virus from the within-cell scale to the between-cell scale through the process of viral shedding or excretion. …”
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Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function by Jennifer L. Schwedler, Maxwell A. Stefan, Christine E. Thatcher, Peter R. McIlroy, Anupama Sinha, Ashlee M. Phillips, Christopher A. Sumner, Colleen M. Courtney, Christina Y. Kim, Dina R. Weilhammer, Brooke Harmon

“…In addition to preventing viral infection through neutralization, Abs can clear infected cells and induce immunomodulatory functions through engagement of their crystallizable fragment (Fc) with complement proteins and Fc receptors on immune cells. …”
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