Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases by Linda Zhou, Thomas H. Leung

“…We describe a single-cell RNA-sequencing–based strategy to interrogate human skin biopsies for viral transcripts, permitting detection of viral infection within a sample, single-cell resolution of virally infected cells and identification of subsequent transcriptomic perturbations. …”
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Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption. by Lauren A Hirao, Irina Grishina, Olivier Bourry, William K Hu, Monsicha Somrit, Sumathi Sankaran-Walters, Chris A Gaulke, Anne N Fenton, Jay A Li, Robert W Crawford, Frank Chuang, Ross Tarara, Maria L Marco, Andreas J Bäumler, Holland Cheng, Satya Dandekar

“…Further, the impact of early viral infection on mucosal responses to pathogenic and commensal microbes has not been investigated. …”
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SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells by Katie V. Tieu, Madaline Espey, Aarthi Narayanan, Rebecca L. Heise, Farhang Alem, Daniel E. Conway

“…Abstract SARS-CoV-2 is a viral infection, best studied in the context of epithelial cell infection. …”
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The increasing importance of Dengue virus infection in Saudi Arabia: A review by Ahmad M. Alharbi

“…Herein, we discuss the epidemiology of dengue viral infection in Saudi Arabia, dengue fever biology and clinical manifestation. …”
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Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells by Christopher A. Alvarez-Breckenridge, Jianhua Yu, Balveen Kaur, Michael A. Caligiuri, E. Antonio Chiocca

“…The immune response to viral infection appears to be an essential factor that determines the efficacy of oncolytic viral therapy. …”
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Analysis of an HIV infection model incorporating latency age and infection age by Jinliang Wang, Xiu Dong

“…There is a growing interest to understand impacts of latent infection age and infection age on viral infection dynamics by using ordinary and partial differential equations. …”
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Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells by Madison R. Mix, Stephanie van de Wall, Mohammad Heidarian, Elizabeth A. Escue, Cori E. Fain, Lecia L. Pewe, Lisa S. Hancox, Sahaana A. Arumugam, Cassie M. Sievers, Vladimir P. Badovinac, John T. Harty

“…However, the impact of repeated peripheral viral infection on the generation, phenotype, localization, and recall responses of brain TRM remains elusive. …”
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Portal-splenic-mesenteric venous thrombosis in COVID-19 patients: a systematic review by Ricardo Zanetti Gomes, Matheus Von Jelita Salina, Vitor Hugo Moro Pironatto, Julia Kapp Lepinski, Tiago Daniel Gueiber, Beatriz Moreira Salles Juliatto, Milena Zadra Prestes, Camila Marinelli Martins

“…In addition to respiratory impairment, this viral infection can also provoke gastrointestinal symptoms caused by vascular disorders, such as portal-splenic-mesenteric venous thrombosis (PSMVT). …”
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How the tulip breaking virus creates striped tulips by Aidan A. Wong, Gustavo Carrero, Thomas Hillen

“…This work shows how a viral infection that inhibits pigment production can lead to beautiful tulip patterns.…”
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Dynamics of coagulation proteins upon ICU admission and after one year of recovery from COVID-19: a preliminary study by Raquel Behar-Lagares, Ana Virseda-Berdices, Ana Virseda-Berdices, Óscar Martínez-González, Óscar Martínez-González, Óscar Martínez-González, Rafael Blancas, Rafael Blancas, Rafael Blancas, Marcela Homez-Guzmán, Eva Manteiga, Juan Churruca-Sarasqueta, Madian Manso-Álvarez, Madian Manso-Álvarez, Madian Manso-Álvarez, Ángela Algaba, Ángela Algaba, Ángela Algaba, Salvador Resino, Salvador Resino, Amanda Fernández-Rodríguez, Amanda Fernández-Rodríguez, María A. Jiménez-Sousa, María A. Jiménez-Sousa

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Glutamine-glutamate centered metabolism as the potential therapeutic target against Japanese encephalitis virus-induced encephalitis by Mengyuan Li, Hang Yuan, Xiaofei Yang, Yingfeng Lei, Jianqi Lian

“…Given that viruses are obligate intracellular parasites, cellular metabolic reprogramming triggered by viral infection is intricately related to the establishment of infection and progression of disease. …”
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COVID-19: An Update on the Latest Therapeutic Agents by Ke-Yan Loo, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Kar-Wai Hong, Kok-Gan Chan, Vengadesh Letchumanan

“…This public health emergency prompted the rapid development of vaccines and treatments to fight against viral infection. Vaccines against the viral infection started rolling out in late 2020, and the distribution of the vaccines worldwide managed to reduce the symptoms of COVID-19 and prevent outbreaks in local communities. …”
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Phenazine biosynthesis-like domain-containing protein (PBLD) and Cedrelone promote antiviral immune response by activating NF-ĸB by Peili Hou, Hongchao Zhu, Fengyun Chu, Yan Gao, Xiaonan Sun, Fuzhen Zhang, Xiaomeng Wang, Yueyue Feng, Xingyu Li, Yu Liu, Jun Wang, Xiaoyun Wang, Daniel Chang He, Hongmei Wang, Hongbin He

“…Here, we demonstrate that PBLD upregulates the type I interferon (IFN-I) response through activating NF-kappaB (NF-κB) signaling pathway to resist viral infection in cells and mice. Mechanistically, PBLD activates NF-κB signaling pathway during viral infection via blocking tripartite motif containing 21 (TRIM21)-mediated phosphorylated inhibitory kappa B kinase beta (IKKβ) degradation. …”
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Efficacy of traditional herb aqua extract of Teucrium stocksianum and its fractions against HSV-1 virus expression levels of genes (UL46 and US6) by Emad Asgari, Zohreh Sharifi, Farahnaz Bineshian, Mahsa Zamanian

“…Time intervals of 24 and 48 hours after viral infection revealed that the cell viability is reduced by the viral infection time (MOI=0.1), log 10-3, p <0.001). …”
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Piezo1-directed neutrophil extracellular traps regulate macrophage differentiation during influenza virus infection by Yuexin Wang, Qiuli Yang, Yingjie Dong, Likun Wang, Zhiyuan Zhang, Ruiying Niu, Yufei Wang, Yujing Bi, Guangwei Liu

“…Abstract Neutrophils and macrophages are critical for antiviral immunity, but their reciprocal regulatory roles and mechanisms in the response to viral infection remain unclear. Herein, we found that the ion channel Piezo1 directs neutrophil extracellular trap (NET) formation and regulates macrophage functional differentiation in anti-influenza virus immunity. …”
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Sleep Quality in Patients with Human Immunodeficiency Virus by Faiha Nurul Aqilah, Iqbal Pramukti, Bambang Aditya Nugraha, Mamat Lukman, Hasniatisari Harun, Siriluk Sithichoksakulchai

“…Human Immunodeficiency Virus (HIV) is a viral infection that occurs in the human immune system and makes the body unable to fight infection because the virus can replicate itself. …”
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Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review by Tsuyoshi Nakayama, Mitsuteru Akahoshi, Kensuke Irino, Yasutaka Kimoto, Yojiro Arinobu, Hiroaki Niiro, Hiroshi Tsukamoto, Takahiko Horiuchi, Koichi Akashi

“…Viral infection is known to induce transient autoimmunity in humans. …”
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Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry. by Nousheen Bibi, Maleeha Shah, Shahzad Khan, Muhammad Shahzad Chohan, Mohammad Amjad Kamal

“…The binding of the spike protein to the b1 domain of NRP1 has been shown to enhance viral infection twofold. Consequently, targeting NRP1 to disrupt this interaction represents a promising strategy to mitigate viral infection. …”
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Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…Globally, SARS-CoV-2 outbreak is considered as pandemic viral infection by the World Health Organization (WHO). …”
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Oncolytic alphavirus-induced extracellular vesicles counteract the immunosuppressive effect of melanoma-derived extracellular vesicles by Darshak K. Bhatt, Annemarie Boerma, Silvina Odete Bustos, Andréia Hanada Otake, Alexis Germán Murillo Carrasco, Patrícia Pintor Reis, Roger Chammas, Toos Daemen, Luciana Nogueira de Sousa Andrade

“…Specifically, we demonstrate that viral infection causes a differential loading of regulatory microRNAs (miRNAs) in EVs in addition to changes in their physical features. …”
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