Picolinic Acid in Patients with Chronic Hepatitis C Infection: A Preliminary Report by Jolanta Zuwała-Jagiello, Monika Pazgan-Simon, Krzysztof Simon, Maria Warwas

“…The rationale for seeking increased PA formation in chronic viral hepatitis is based on the involvement of activated macrophages in chronic viral hepatitis-associated inflammation. …”
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Antibody to Hepatitis C Virus in Risk Groups in Canada by RK Chaudhary, Theresa Mo

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Genotype 3 is linked to worse liver disease progression in hepatitis C patients even after SVR following DAA therapy by Xiping Ran, Xiping Ran, Yang Xu, Ying Wang, Cheng Zeng, Chen Gong, Ni Wang, Dachuan Cai, Dachuan Cai

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Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparati... by Melashu Balew Shiferaw, Ketema Tafess Tulu, Amtatachew Moges Zegeye, Amarech Asratie Wubante

“…Blood specimen was collected to determine alanine aminotransferase (ALT) and aspartate aminotransferase (AST), CD4 count, and viral hepatitis. The prevalence of liver enzyme abnormality was 20.1% and 22.0% among HAART experienced and HAART naïve patients, respectively. …”
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Characteristics of TPT initiation and completion among people living with HIV by L. Gunde, A. Wang, D. Payne, S. O'Connor, A. Kabaghe, N. Kalata, A. Maida, D. Kayira, V. Buie, L. Tauzi, A. Sankhani, A. Thawani, E. Rambiki, A. Ahimbisibwe, T. Maphosa, K. Kudiabor, R. Nyirenda, J. Mpunga, K. Mbendera, P. Nyasulu, F. Kayigamba, M. Farahani, A. C. Voetsch, K. Brown, A. Jahn, B. Girma, K. Mirkovic, the MPHIA Survey Team

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Impact of Hepatitis B Exposure on Sustained Virological Response Rates of Highly Viremic Chronic Hepatitis C Patients by Ioannis S. Elefsiniotis, Christos Pavlidis, Elena Vezali, Theodoros Mariolis-Sapsakos, Sotirios Koutsounas, George Saroglou

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Prevalence and trends of transfusion transmissible infections among blood donors in Basra, Iraq by Khairallah A S Mohammed, Maha M Hameed, Abdullah H Mousa, Amar T Saleh

“…A total of 197 898 samples were collected and screened for hepatitis B surface antigen (HBsAg), anti-hepatitis B core (HBc), anti-hepatitis C virus (HCV) and syphilis immunologically.Results The prevalence rates of seropositive of viral hepatitis for the year 2019, 2020, 2021 were as following: hepatitis B virus (HBV) rates 1.54%, 1.45% and 1.14% with significant declined trend by 26%; anti-HCV rates were 0.14, 0.12 and 0.11% with significant declined trend by 21.4%; and the syphilis rates were 0.38, 0.47, 0.36 with marked declined trend 5.3%, respectively.Of those donors showed HBV positive, 2503 (1.26%) had positive anti-HBc results, while only 173 (0.0874) showed positive test results for both anti-HBc and HBsAg.Conclusion Prevalence rates of viral hepatitis and syphilis showed a steady decline between 2019 and 2021, and these rates were much lower in Basra than in other parts of Iraq and neighbouring countries. …”
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Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease by Tomonori Sugita, Katsushi Amano, Masanori Nakano, Noriko Masubuchi, Masahiro Sugihara, Tomokazu Matsuura

“…The levels of UDCA and GUDCA were significantly higher in the ALD group, and the levels of DCA and UDCA were significantly lower in the biliary tract diseases group than in viral hepatitis group. In the UDCA therapy (−) subgroup, a significantly lower level of TLCA was observed in the ALD group, with lower levels of CDCA, DCA, and GLCA noted in biliary tract diseases group compared to viral hepatitis group. …”
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Liver Dysfunction Associated with Intravenous Methylprednisolone Pulse Therapy in Patients with Graves’ Orbitopathy by Hiroyuki Eguchi, Junichi Tani, Saori Hirao, Munehisa Tsuruta, Ichiro Tokubuchi, Kentaro Yamada, Masataka Kasaoka, Yasuo Teshima, Tatsuyuki Kakuma, Yuji Hiromatsu

“…It suggests that, in patients with GO, evaluation of preexisting risk factors—including viral hepatitis—and careful weekly monitoring of liver function during IVMP therapy and monthly thereafter for 12 months are warranted.…”
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Analysis of the 2016 – 2025 fiscal budget of U.S. Centers for Disease Control and Prevention by Nana LIU, Lieyu HUANG, Yuan DANG, Zekai YU, Qianqiu LIU, Yan GUO

“…From 2016 to 2025, the allocation of basic funds/project budgets mainly focused on areas such as "HIV/AIDS, Viral Hepatitis, STD, and TB Prevention," "Chronic Disease Prevention and Health Promotion," and "Immunization and Respiratory Diseases," all accounting for more than 10% of the total budget. …”
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Exploration of the Role of Cyclophilins in Established Hepatitis B and C Infections by Jennifer Molle, Sarah Duponchel, Jennifer Rieusset, Michel Ovize, Alexander V. Ivanov, Fabien Zoulim, Birke Bartosch

“…Amongst the Cyp family, the molecular mechanisms underlying the antiviral effects of CypA have been investigated in detail, but potential roles of other Cyps are less well studied in the context of viral hepatitis. Furthermore, most studies investigating the role of Cyps in viral hepatitis did not investigate the potential therapeutic effects of their inhibition in already-established infections but have rather been performed in the context of neo-infections. …”
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Etiology and Outcome of Acute Liver Failure: Experience from a Liver Transplantation Centre in Montreal by Geneviève Tessier, Edith Villeneuve, Jean-Pierre Villeneuve

“…BACKGROUND: Acute liver failure is a rare condition in which massive liver injury is associated with the rapid development of hepatic encephalopathy. Although viral hepatitis and drug-induced liver injury are the most common causes, no specific etiology is found in a substantial proportion of cases reported from Europe and the United States.…”
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Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 by Leisha D. Nolen, Courtney Gustin, Sara Seeman, Neil Murphy, Sarah Truitt, Sarah Schillie, Michael G. Bruce, Dana Bruden, James Tiesinga, Brian McMahon

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The Role of Liver Biopsy in the Management of Patients with Liver Disease by Florence Wong

“…Prognostic information can be obtained in patients with this disorder, as well as in those with alcoholic liver disease and viral hepatitis, and liver biopsy can be used as a guide to their management.…”
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Aetiology of chronic liver disease is a valuable factor for stratifying adverse outcomes of acute decompensation: prospective observational study by Jung Hee Kim, Sung-Eun Kim, Do Seon Song, Hee Yeon Kim, Eileen L. Yoon, Ji Won Park, Tae Hyung Kim, Young-Kul Jung, Ki Tae Suk, Hyung Joon Yim, Jung Hyun Kwon, Sung Won Lee, Seong Hee Kang, Moon Young Kim, Soung Won Jeong, Jae-Young Jang, Jeong Ju Yoo, Sang Gyune Kim, Young-Joo Jin, Gab Jin Cheon, Byung Seok Kim, Yeon Seok Seo, Hyoungsu Kim, Dong Hyun Sinn, Woo Jin Chung, Hwi Young Kim, Han Ah Lee, Seung Woo Nam, In Hee Kim, Ji Hoon Kim, Hee Bok Chae, Joo Hyun Sohn, Ju Yeon Cho, Yoon Jun Kim, Jin Mo Yang, Jung Gil Park, Won Kim, Hyun Chin Cho, Dong Joon Kim

“…The most common aetiology of CLD was alcohol (n = 1021), followed by viral hepatitis (n = 206), viral hepatitis with alcohol-related (n = 129), cryptogenic (n = 108) and autoimmune (n = 37). …”
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HIV Infection and TLR Signalling in the Liver by Megan Crane, Kumar Visvanathan, Sharon R. Lewin

“…Despite the availability of effective combination antiretroviral therapy (cART), liver disease is one of the leading causes of morbidity and mortality in Human Immunodeficiency Virus (HIV)-infected individuals, specifically, in the presence of viral hepatitis coinfection. HIV, a single stranded RNA virus, can bind to and activate both Toll-like receptor (TLR)7 and TLR8 in circulating blood mononuclear cells, but little is known about the effect of HIV on TLRs expressed in the liver. …”
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Hyperferritinemia in the Chinese and Asian Community: A Retrospective Review of the University of British Columbia Experience by Paul R Yenson, Eric M Yoshida, Charles H Li, Henry V Chung, Peter WK Tsang

“…The etiology of hyperferritinemia in the Asia-Pacific population is less clear due to a low prevalence of known HFE mutations such as C282Y and H63D, as well as an increased prevalence of viral hepatitis and hereditary anemia. A retrospective case review of 80 patients of Asian ethnicity referred to three subspecialists in tertiary care teaching hospitals between January 1997 and March 2005 for assessment of hyperferritinemia was performed.…”
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Stauffer’s Syndrome in Patient with Metastatic Prostate Cancer by Andris Romašovs, Aldis Puķītis, Viktorija Mokricka, Elina Frolova

“…Cholestasis is a symptom that can be present in many conditions, such as bile duct obstruction by malignant mases, obstruction by gallstone, acute and chronic viral hepatitis, and autoimmune disorders, such as primary biliary and sclerosing cholangitis. …”
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Serological Evidence of Hepatitis B and E and Dengue Coinfection in Chadian Patients and Impact on Lipidemia Profile by Alexandre Kanga Djasrabe, Borris Rosnay Tietcheu Galani, Moussa Mahamat Ali, Fissou Henry Yandai, Bessimbaye Nadlaou, Mayann Habkreo, Nicolas Yanou Njintang

“…Objective. Viral hepatitis is an endemic disease in Chad. However, few studies have documented coinfection cases and their impact on cardiovascular risk. …”
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Albumin Binding Function: The Potential Earliest Indicator for Liver Function Damage by Penglei Ge, Huayu Yang, Jingfen Lu, Wenjun Liao, Shunda Du, Yingli Xu, Haifeng Xu, Haitao Zhao, Xin Lu, Xinting Sang, Shouxian Zhong, Jiefu Huang, Yilei Mao

“…Currently there is no indicator that can evaluate actual liver lesion for early stages of viral hepatitis, nonalcoholic fatty liver disease (NAFLD), and cirrhosis. …”
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