The impact of vaccines and vaccinations: Challenges and opportunities for modelers by Roy Curtiss III

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The dilemma of X-linked agammaglobulinemia carriers by Federica Pulvirenti, MD, PhD, Cinzia Milito, MD, PhD, Francesco Cinetto, MD, PhD, Giulia Garzi, MD, Germano Sardella, MD, Giuseppe Spadaro, MD, Francesca Lippi, MD, Valentina Guarnieri, MD, Bianca Laura Cinicola, MD, Maria Carrabba, MD, PhD, Daniele Guadagnolo, MD, Giovanna Fabio, MD, Baldassarre Martire, MD, Caterina Cancrini, MD, PhD, Giulia Lanzoni, MD, Andrea Finocchi, MD, PhD, Gigliola Di Matteo, MD, PhD, Eva Pompilii, MD, Simona Ferrari, BD, PhD, Isabella Quinti, MD, PhD

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Acute respiratory tract infections during the first 6 years of life – results from the German birth cohort study LoewenKIDS by Bianca Klee, Sophie Diexer, Susan Langer, Cornelia Gottschick, Carla Hartmann, Nadine Glaser, Johannes Horn, Evelyn Dorendorf, Heike Raupach-Rosin, Lamiaa Hassan, Nicole Rübsamen, Kristin Maria Meyer-Schlinkmann, Carlos A. Guzman, Valerie Heselich, Eva Battin, Thomas Pietschmann, Dietmar H. Pieper, Mathias Pletz, Peggy Riese, Stephanie Trittel, Saskia Thies, Constantin von Kaisenberg, Frank Dressler, Florian Guthmann, Carsten Oberhoff, Ralf L. Schild, Andre Karch, Rafael Mikolajczyk

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The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity by Cuong J. Tran, Zahra Zubair-Nizami, Ingeborg M. Langohr, Matthew D. Welch

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Exploring AI governance in the Middle East and North Africa (MENA) region: gaps, efforts, and initiatives by Hana Trigui, Fatma Guerfali, Emna Harigua-Souiai, Radwan Qasrawi, Chiraz Atri, Elie Salem Sokhn, Christo El Morr, Karima Hammami, Oussama Souiai, Jianhong Wu, Jude Dzevela Kong, Jean Jacques Rousseau, Sadri Znaidi

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Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context by Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Djibrilla Issiaka, Adrian VS Hill, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Mehreen Datoo, Mala Sylla, Abdrahmane Boncane Dicko

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Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology by M. V. Sprindzuk, A. S. Vladyko, L. P. Titov, Lu Zhuozhuang, V. I. Bernik

“…The article is focused on the study of algorithms for processing bioinformatic data of genomic origin predominantly for the purposes of predominantly immunoinformatics and computational vaccinology. The schemes of algorithms developed by the authors for the analysis of bioinformatic data are presented. …”
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Routine Immunization of Adults in Canada: Review of the Epidemiology of Vaccine-Preventable Diseases and Current Recommendations for Primary Prevention by Michael D Parkins, Shelly A McNeil, Kevin B Laupland

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Heterogeneity of Rotavirus Testing and Admitting Practices for Gastroenteritis among 12 Tertiary Care Pediatric Hospitals: Implications for Surveillance by Julie A. Bettinger, Kathryn Wills, Nicole Le Saux, David W Scheifele, Scott A. Halperin, Wendy Vaudry, Members of the Canadian Immunization Monitoring Program, ACTive (IMPACT)

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Global, regional, and national burden inequality of chronic kidney disease, 1990–2021: a systematic analysis for the global burden of disease study 2021 by Jingxun Guo, Jingxun Guo, Zhen Liu, Zhen Liu, Pengjun Wang, Heming Wu, Kai Fan, Kai Fan, Jianbo Jin, Jianbo Jin, Lan Zheng, Lan Zheng, Zeyu Liu, Zeyu Liu, Renyi Xie, Renyi Xie, Renyi Xie, Cheng Li, Cheng Li, Cheng Li, Cheng Li

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Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205 by Luciana D’Apice, Valerio Costa, Rossella Sartorius, Maria Trovato, Marianna Aprile, Piergiuseppe De Berardinis

“…The filamentous bacteriophage fd, codisplaying antigenic determinants and a single chain antibody fragment directed against the dendritic cell receptor DEC-205, is a promising vaccine candidate for its safety and its ability to elicit innate and adaptive immune response in absence of adjuvants. By using a system vaccinology approach based on RNA-Sequencing (RNA-Seq) analysis, we describe a relevant gene modulation in dendritic cells pulsed with anti-DEC-205 bacteriophages fd. …”
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Advancing veterinary vaccines design through trained immunity insights by Xin Wang, Xin Wang, Xin Wang, Xin Wang, Guohua Yu, Guohua Yu, Guohua Yu

“…This approach could revolutionize veterinary vaccinology by offering enhanced efficacy and cross-protection against heterologous infections, particularly valuable for zoonotic disease control.…”
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Towards an HCV vaccine: an overview of the immunization strategies for eliciting an effective B-cell response by Gabriel L. Costa, Giuseppe A. Sautto

“…While progress has been made in this direction, continued investigations on the HCV virology, immunology, and vaccinology are essential to surmount associated obstacles, heling in the development of an HCV vaccine that can benefit the global public health.…”
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Comparative evaluation of sensititre YeastOne and VITEK2 antifungal susceptibility tests with CLSI broth microdilution method of clinical Cryptococcus isolates in Taiwan by Tzu-Ping Weng, Shin-Wei Wang, Shih-Ting Lo, Shu-Li Su, Ming-I Hsieh, Pei-Jane Tsai, Pei-Fang Tsai, Chi-Jung Wu, Nan-Yao Lee, Wen-Chien Ko, Po-Lin Chen

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Analysis of a case of pilomatricoma in an adolescent after receiving recombinant hepatitis B vaccine (CHO cell) in Beijing of China by Li Li, Jingyi Xu, Dongkun Zhang, Jianlin Cai, Zhen Li, Xiaohui Zhang, Shuping Li

“…Based on the professional branch of this case, we organized a seminar and we invited specialists in vaccinology, epidemiology, dermatology, infectiology, and immunology to participate in the conference. …”
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State of the Art, Unresolved Issues, and Future Research Directions in the Fight against Hepatitis C Virus: Perspectives for Screening, Diagnostics of Resistances, and Immunization by Cecilia Trucchi, Andrea Orsi, Cristiano Alicino, Laura Sticchi, Giancarlo Icardi, Filippo Ansaldi

“…Advances in molecular vaccinology, together with a strong financial, political, and societal support, will enable reaching this fundamental success in the coming years. …”
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Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity against Burkholderia cenocepacia infection in mice by Wesam E. Gawad, Yosra I. Nagy, Tamer M. Samir, Ahmed Mohamed Ibrahim Mansour, Omneya M. Helmy

“…We aimed to identify vaccine candidates using reverse vaccinology and evaluate their efficacy as protein-loaded chitosan: pectin nanoparticles (C:P NPs) in a vaccine model. …”
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Functional Potential and Chemical Profile Analysis of Propolis Oil Extracted from Propolis of Balochistan by Saliha Aziz, Ali Akbar, Zareen Gul, Muhammad Bilal Sadiq, Jahangir Khan Achakzai, Nazir Ahmad Khan, Abdul Samad, Zia Ur Rehman, Imran Ali

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In-silico formulation of a next-generation polyvalent vaccine against multiple strains of monkeypox virus and other related poxviruses. by Abu Tayab Moin, Nurul Amin Rani, Rajesh B Patil, Tanjin Barketullah Robin, Md Asad Ullah, Zahidur Rahim, Md Foyzur Rahman, Talha Zubair, Mohabbat Hossain, A K M Moniruzzaman Mollah, Nurul Absar, Mahboob Hossain, Mohammed Abul Manchur, Nazneen Naher Islam

“…This study utilized a reverse vaccinology approach to retrieve conserved epitopes for monkeypox virus and construct a vaccine that could provide cross-protection against related viruses with similar antigenic properties. …”
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How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines by R. Gasparini, D. Panatto, N. L. Bragazzi, P. L. Lai, A. Bechini, M. Levi, P. Durando, D. Amicizia

“…The understanding of these mechanisms has opened new horizons in the field of vaccinology. Nowadays different licensed meningococcal vaccines are available and used: conjugate meningococcal C vaccines, tetravalent conjugate vaccines, an affordable conjugate vaccine against the N. menigitidis serogroup A, and universal vaccines based on multiple antigens each one with a different and peculiar function against meningococcal group B strains.…”
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