Potential of germanium-based compounds in coronavirus infection by NAROKHA VIOLETTA, NIZHENKOVSKA IRYNA, KUZNETSOVA OLENA

“…Germanium-based compounds have shown the ability to influence the replication of various DNA/RNA viruses, stimulate the body’s natural resistance, prevent the development of metabolic intoxication of various origin, increase the efficacy of vaccines, and prevent the development of excessive accumulation of reactive oxygen species, which plays a decisive role in the development of inflammatory response caused by a viral infection. …”
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Gene Carriers and Transfection Systems Used in the Recombination of Dendritic Cells for Effective Cancer Immunotherapy by Yu-Zhe Chen, Xing-Lei Yao, Yasuhiko Tabata, Shinsaku Nakagawa, Jian-Qing Gao

“…Reported research in animal studies indicated that vaccine immunity could be a promising alternative therapy for cancer patients. …”
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Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation. by Louis Kuijpers, Evdokia-Anastasia Giannopoulou, Yuzhen Feng, Wouter van den Braak, Abbas Freydoonian, Ramon Ramlal, Hugo Meiring, Belén Solano, Wouter H Roos, Arjen J Jakobi, Leo A van der Pol, Nynke H Dekker

“…To counteract hand, foot, and mouth disease-causing viruses such as enterovirus A71 and coxsackievirus A6, virus-like particles (VLPs) have emerged as a leading contender for the development of a multivalent vaccine. However, VLPs have shown rapid conversion from a highly immunogenic state to a less immunogenic state and low particle integrity lifetimes compared to inactivated virus vaccines, thus raising concerns about their overall stability. …”
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Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy. by Sidra Zafar, Yuhe Bai, Syed Aun Muhammad, Jinlei Guo, Haris Khurram, Saba Zafar, Iraj Muqaddas, Rehan Sadiq Shaikh, Baogang Bai

“…To overcome the therapeutic challenges and exploration of immunotherapeutic options, broad spectral therapeutic vaccines could have significant impact. Based on immunoinformatic and integrated machine learning tools, we predicted the potential therapeutic vaccine candidates of liver cancer. …”
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Induced protein expression in Leptospira spp. and its application to CRISPR/Cas9 mutant generation by L. G. V. Fernandes, A. L. T. O. Nascimento, J. E. Nally

“…These newly controlled protein expression systems will advance studies on the basic biology and virulence of Leptospira, as well as facilitate knockout mutant generation for improved veterinary vaccines.…”
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Bioterrorism in Canada: An Economic Assessment of Prevention and Postattack Response by Ronald St John, Brian Finlay, Curtis Blair

“…Rapid implementation of a postattack prophylaxis program that includes the stockpiling of antibiotics, vaccines and antitoxins; training of first responders in the diagnosis, handling and treatment of pathogens; and the general enhancement of Canada's response capability would reduce both human and economic losses.…”
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ASSISTED REPRODUCTIVE TECHNOLOGY BETWEEN MEDICINE, RELIGION AND LAW by Dan LUPAȘCU, Ioana PĂDURARIU

“…That is what we do by nature: we figure out how things work and we make new steps, over and over. We created vaccines to help prevent diseases and, in the future, maybe we are about to create a human being outside the womb. …”
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Effectiveness of bovine immunoglobulin g against salmonella infections in mice by Hasan Hüseyin Hadimli, Gökçenur Sanioğlu Gölen, Zafer Sayın

“…<p> <b> Results:</b> The antibodies titres in blood of immunized cattle were found to be high than before vaccination and controls. The numbers of morbidity and mortality in groups of vaccine were determined as 9 in combined vaccine (6 in S. …”
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Beyond immortality: Epstein–Barr virus and the intricate dance of programmed cell death in cancer development by Arezoo Esmaeili, Prankur Awasthi, Samira Tabaee

“…Furthermore, the insights gleaned from this review could catalyze the design of vaccines aimed at preventing EBV infection or curtailing its oncogenic impact. …”
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THE INFLUENCE OF MOTHER'S KNOWLEDGE AND ATTITUDE ON BASIC IMMUNIZATION COVERAGE by Nina Herlina, erik ekowati, Alfida Faqih Dhea firanti, Elsya Hildatrian, Fairy Prudencia, Wanelis Wanelis, Nabilla Ramadhani

“…Background: Basic Immunization is the administration of vaccines to infants aged 0-18 months. The success of the basic immunization program in infants is supported by the important role of parents who are responsible for their babies Objective: To determine the influence of mothers' knowledge and attitudes on basic immunization coverage. …”
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SPREAD OF LOW PATHOGENIC AVIAN INFLUENZA А/Н9N2 IN THE WORLD AND RUSSIAN FEDERATION. CHALLENGES OF DISEASE ERADICATION by M. S. Volkov, A. V. Varkentin, V. N. Irza

“…Н9 virus circulation is reflected not only in the physical condition of birds and their productivity, but it also affects the live vaccines’ efficacy during scheduled immunizations through the reduction of their protective effect and increase of post-vaccination reactions. …”
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In Silico Study of Alkaloids: Neferine and Berbamine Potentially Inhibit the SARS-CoV-2 RNA-Dependent RNA Polymerase by Rishab Marahatha, Asmita Shrestha, Kabita Sharma, Bishnu P. Regmi, Khaga Raj Sharma, Pramod Poudel, Ram Chandra Basnyat, Niranjan Parajuli

“…While there have been some vaccines and drugs, the rapid emergence of variants due to mutations has threatened public health. …”
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Nucleic acid therapeutics: Past, present, and future by Sajid Naeem, Ju Zhang, Yang Zhang, Yu Wang

“…The field of nucleic acid therapeutics has been brought to the forefront by the rapid development of vaccines against COVID-19, followed by a number of approvals for clinical use including much anticipated CRISPR-Cas9. …”
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COVID-19 and the Medical Devices in India: Trade for a Resilient Health System by Ravinder Jha, Diwas Saun, Indrani Gupta

“…The COVID-19 pandemic exposed a lack of resilience in areas of drugs and vaccines but also in medical products. Objectives: The study analyzes India’s strengths and weaknesses in the trade of medical devices and identifies specific devices where India can attain self-sufficiency and areas where trade is still beneficial. …”
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Quinoline and Quinazoline Alkaloids against COVID-19: An In Silico Multitarget Approach by Esraa M. O. A. Ismail, Shaza W. Shantier, Mona S. Mohammed, Hassan H. Musa, Wadah Osman, Ramzi A. Mothana

“…Although, recently, vaccines have been approved for the prevention of COVID-19, there is still an urgent need for the discovery of more efficacious and safer drugs especially from natural sources. …”
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Characterization of environmental and clinical surveillance inputs to support prospective integrated modeling of the polio endgame. by Kamran Badizadegan, Kimberly M Thompson

“…Relatively recently, the GPLN expanded to include environmental surveillance to obtain additional information about poliovirus transmission in some geographies and to increase confidence about the absence of poliovirus transmission after successful eradication and/or the cessation of use of live-attenuated oral poliovirus vaccines (OPVs). Historical polio eradication strategic plans anticipated that successful global poliovirus eradication would lead to reduced requirements for financial investments for a poliovirus-specific surveillance system, and consequent transition of capacity and resources into integrated national disease surveillance systems. …”
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Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals by Ghyda Murad Hashim, Mehdi Shahgolzari, Kathleen Hefferon, Afagh Yavari, Srividhya Venkataraman

“…Also addressed are plant-derived anti-cancer vaccines, nanoparticles, monoclonal antibodies, and immunotherapies. …”
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The Immune Response to Tumors as a Tool toward Immunotherapy by F. Pandolfi, R. Cianci, D. Pagliari, F. Casciano, C. Bagalà, A. Astone, R. Landolfi, C. Barone

“…Immunotherapy of tumors has developed several techniques: immune cell transfer, vaccines, immunobiological molecules such as monoclonal antibodies that improve the immune responses to tumors. …”
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Natural compounds from medicinal plants against COVID-19 by Anton Kolodnitsky, Nikita Ionov, Irina Gravel, Vladimir Poroikov

“…Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. …”
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RISK OF INTRODUCING HIGHLY DANGEROUS ANIMAL VESICULAR DISEASES INTO THE RUSSIAN FEDERATION by V. P. Semakina, T. P. Akimova, I. Yu. Solomatina, A. K. Karaulov

“…The transboundary spread of vesicular diseases is mainly caused by legal and illegal movements of animals, animal products, feeds, live vaccines; migration of wild animals across the borders from neighboring countries and passive mechanical transmission of infection. …”
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