Differential regulation of the release of tumor necrosis factor-α and of eicosanoids by mast cells in rat airways after antigen challenge by Aryene Goes Trezena, Zilma Lucia da Silva, Ricardo Martins Oliveira-filho, Amilcar Sabino Damazo, Anita Hilda Straus, Helio Kiyoshi Takahashi, Sonia Maria Oliani, Wothan Tavares de Lima

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Impact of COVID-19 on routine childhood immunisations in low- and middle-income countries: A scoping review. by Milena Dalton, Benjamin Sanderson, Leanne J Robinson, Caroline S E Homer, William Pomat, Margie Danchin, Stefanie Vaccher

“…Routine vaccines are critical to child health. The COVID-19 pandemic significantly impacted essential health services, particularly in low-and middle-income countries (LMICs). …”
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The Informed Consent in Allergology from a Scientific, Technological and Social Perspective by Marisela Luisa Pérez Pacaréu, Yanet Morejón del Rosario, Gloria Arlenys Suárez Rodríguez, Aleima Rodríguez Carbajal

“…This paper reviews the application of the informed consent within the specialty of allergology in procedures (skin tests), therapeutic interventions (immunotherapy) and research (clinical trials) from a scientific, technological and social perspective, based on the advances achieved in Cuba in recent years to obtain better allergenic extracts for testing, high-quality vaccines and new drugs to benefit the allergic patient. …”
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Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus by Kam Lun Hon, Margaret Ip, Winnie Chiu Wing Chu, William Wong

“…We report a young girl who died of Streptococcus pneumoniae 19A pneumonia, septic shock, and hemolytic uremic syndrome despite prior pneumococcal vaccination, appropriate antibiotics, and aggressive intensive care support. …”
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Design and Performance of Solar PV Integrated Domestic Vapor Absorption Refrigeration System by Divya Arputham Selvaraj, Kirubakaran Victor

“…They can also help lifesaving vaccines to reach even the isolated parts of the world. …”
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AAV-based vectors for human diseases modeling in laboratory animals by Timur I. Aliev, Dmitry V. Yudkin

“…The development of therapeutic drugs and vaccines requires the availability of appropriate model animals that replicate the pathogenesis of human diseases. …”
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Strategies to Overcome Antileishmanial Drugs Unresponsiveness by Shyam Sundar, Anup Singh, Om Prakash Singh

“…In the absence of effective vector control measures and vaccines against leishmaniasis, effective chemotherapy remains the mainstay of treatment. …”
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Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection by Zeyu Liu, Xue Li, Xiaohong Li, Xingyu Yan, Yuan Tian, Yue Zhao, Kexin Liu, Pei Hao, Shuye Zhang, Chao Zhang

“…Licensed inactivated EV-A71 vaccines do not provide cross-protection against other enteroviruses. …”
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Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology by M. V. Sprindzuk, A. S. Vladyko, L. P. Titov, Lu Zhuozhuang, V. I. Bernik

“…However, for the complete analysis and implementation of, for example, the epitope vaccines, subsequent validation by the laboratory and in vivo experiments are required.…”
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Aging Adults and Seasonal Influenza: Does the Vitamin D Status (H)Arm the Body? by Pierre Olivier Lang, Dimitrios Samaras

“…Evidence that VitD affects clearance of selected pathogens is supported by epidemiological and clinical data, while its coadministration with influenza vaccine in mice enhanced both mucosal and systemic antibody responses. …”
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Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections by Aziz Alami Chentoufi, Lbachir BenMohamed

“…The progress and limitations in developing a safe and efficient mucosal herpes vaccine are discussed.…”
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New Immunotherapeutic Approaches for Glioblastoma by Gustavo Ignacio Vázquez Cervantes, Dinora F. González Esquivel, Saúl Gómez-Manzo, Benjamín Pineda, Verónica Pérez de la Cruz

“…The immunotherapies for GMB including monoclonal antibodies, checkpoint inhibitors, vaccines, and oncolytic viruses, among others, have shown favorable results alone or as a multimodal treatment. …”
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Anti-HSV-1 agents: an update by Wenwen Lv, Lei Zhou, Jia Wu, Jishuai Cheng, Yongzhong Duan, Wen Qian

“…To date, there are no approved commercially available vaccines, and anti-HSV-1 drugs such as specific or non-specific nucleotide (nucleoside) analogs and helicase-primase inhibitors have become the main clinical agents for the treatment of HSV-1 infections despite challenges from resistance. …”
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Current strategies in diagnostics and therapeutics against novel coronavirus disease (COVID-19) by ALOTAIBI FAISAL

“…However, in several areas of the world, vaccination initiatives took place; the vaccines’ safety and efficacy to control the outbreak is yet to be identified. …”
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Immunogenetic Factors Associated with Severe Respiratory Illness Caused by Zoonotic H1N1 and H5N1 Influenza Viruses by Jennifer Juno, Keith R. Fowke, Yoav Keynan

“…By better defining the role of genetic variability in influenza infection and identifying key polymorphisms that impair the host immune response or correlate with protection, we will be able to better identify at-risk populations and new targets for therapeutic interventions and vaccines. This paper will summarize known immunogenetic factors associated with susceptibility or severity of both pH1N1 and H5N1 infections and will also identify genetic pathways and polymorphisms of high relevance for future study.…”
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Fundamentals and Methods for T- and B-Cell Epitope Prediction by Jose L. Sanchez-Trincado, Marta Gomez-Perosanz, Pedro A. Reche

“…There is great interest in identifying epitopes in antigens for a number of practical reasons, including understanding disease etiology, immune monitoring, developing diagnosis assays, and designing epitope-based vaccines. Epitope identification is costly and time-consuming as it requires experimental screening of large arrays of potential epitope candidates. …”
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Decision Support System Based on CoCoSo Method with the Picture Fuzzy Information by Muhammad Qiyas, Muhammad Naeem, Saifullah Khan, Saleem Abdullah, Thongchi Botmart, Tajammul Shah

“…The number of instances of this disease is increasing at an exponential, but there are now commercially accessible COVID-19 vaccines. The weak symptoms of COVID-19 disease, on the other hand, are treated with a variety of antiviral treatments. …”
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Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature by Angus Nnamdi Oli, Samson Adedeji Adejumo, Adekunle Babajide Rowaiye, Joyce Oloaigbe Ogidigo, Jarrad Hampton-Marcell, Gordon C. Ibeanu

“…We critically evaluate the current immunotherapy approaches, including cancer vaccines, adoptive T cell therapies, and cytokine-based treatments, highlighting their efficacy and safety. …”
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Long-Term Survival and PSA Control with Radiation and Immunotherapy for Node Positive Prostate Cancer by M. Kamrava, Kwong Y. Tsang, R. A. Madan, A. Kaushal, C. N. Coleman, J. Gulley

“…Further evaluation of therapeutic cancer vaccines in combination with radiation and hormonal therapy in the definitive management of prostate cancer is warranted.…”
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Heat stable and intrinsically sterile liquid protein formulations by Atip Lawanprasert, Harminder Singh, Sopida Pimcharoen, Mariangely González Vargas, Arshiya Dewan, Girish S. Kirimanjeswara, Scott H. Medina

“…Abstract Over 80% of biologic drugs, and 90% of vaccines, require temperature-controlled conditions throughout the supply chain to minimize thermal inactivation and contamination. …”
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