Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma by Yujiao Zhou, Feifei Liu, Chengmin Li, Guo Shi, Xiaolei Xu, Xue Luo, Yuanling Zhang, Jingjie Fu, Aizhong Zeng, Limin Chen

“…Secondly, bone marrow-derived DCs were infected by Ad-AAH-IRES2-EGFP to yield AAH-DC vaccines. Matured DCs were demonstrated by increased expression of CD11c, CD80, and MHC-II costimulatory molecules. …”
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COVID-19 workplace countermeasures that occupational physicians could not change in Japan: a qualitative study by Yu Igarashi, Seiichiro Tateishi, Juri Matsuoka, Tomoko Sawajima, Mika Kawasumi, Arisa Harada, Koji Mori

“…The responses were categorized into basic systems, occupational health services, workplace countermeasures, vaccines, and incidents, with a code count of 7, 8,147, 10, and 82, respectively. …”
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Difficulties faced by physicians from four European countries in rebutting antivaccination arguments: a cross-sectional study by Fernanda Rodrigues, Cornelia Betsch, Pierre Verger, Harriet Fisher, Philipp Schmid, Dawn Holford, Angelo Fasce, Amanda Garrison, Linda Karlsson, Frederike Taubert, Stephan Lewandowsky, Anna Soveri

“…Introduction Physicians play a critical role in encouraging their patients to get vaccinated, in part by responding to patients’ concerns about vaccines. …”
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Choosing the most suitable NGS technology to combine with a standardized viral enrichment protocol for obtaining complete avian orthoreovirus genomes from metagenomic samples by Sonsiray Álvarez-Narváez, Sonsiray Álvarez-Narváez, Telvin L. Harrell, Islam Nour, Sujit K. Mohanty, Steven J. Conrad

“…Currently available commercial vaccines are ineffective against new ARV variants and ARV outbreaks are increasing worldwide, requiring whole genome sequencing (WGS) to characterize strains that evade vaccines. …”
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Primary ciliary dyskinesia: Meeting the challenges of diagnosis in South Africa by Z Dangor, M Birkhead, C Verwey, D Gray, A Vanker, L Githinji, A Goga, R Masekela, M Zampoli

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Omicron: The rising fear for another wave in Malaysia by Lydia Ngiik-Shiew Law, Ke-Yan Loo, Joanna Xuan Hui Goh, Priyia Pusparajah

“…Pharmaceutical companies raced against the time to develop vaccines, believing that it would be sufficient to control COVID-19. …”
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Diagnosis and Management of Bacterial Meningitis in the Paediatric Population: A Review by Catherine L. Tacon, Oliver Flower

“…Over recent decades new vaccines have led to a change in epidemiology of the disease; however, it remains a condition that requires a high index of suspicion, prompt diagnosis, and early management in the emergency department. …”
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The effect of heat stress on humoral immnuity in broyler chickens by H. Hüseyin Hadimli, Kürşat Kav, Osman Erganiş

“…The broilers were mucosally and orally vaccinated with ND and IB vaccines at 1 and 17 days, respectively. …”
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EDITORIAL PAPER - MEDICAL TECHNIQUES by JT ADMIN

“…Health technology research could be in the form of procedures, vaccines, devices and systems as outlined by the world health organization in its Health technology assessment report. …”
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The Involvement of Microglial Cells in Japanese Encephalitis Infections by Thananya Thongtan, Chutima Thepparit, Duncan R. Smith

“…Despite the availability of effective vaccines, Japanese encephalitis virus (JEV) infections remain a leading cause of encephalitis in many Asian countries. …”
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Tailored Therapy in Lung Cancer by George Rakovich, Lise Tremblay

“…In addition, other related areas of active investigation, including tumour vaccines and pharmacogenetics, are briefly reviewed.…”
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Immunisation schedule of the Pediatric Spanish Association: 2024 recommendations by Francisco José Álvarez García, Antonio Iofrío de Arce, Javier Álvarez Aldeán, Elisa Garrote Llanos, Lucía López Granados, María Luisa Navarro Gómez, Valentín Pineda Solas, Irene Rivero Calle, Jesús Ruiz-Contreras, Ignacio Salamanca de la Cueva, Pepe Serrano Marchuet, Francisco José Álvarez García, Antonio Iofrío de Arce, Javier Álvarez Aldeán, María Garcés-Sánchez, Elisa Garrote Llanos, Abián Montesdeoca Melián, María Luisa Navarro Gómez, Valentín Pineda Solas, Irene Rivero Calle, Jesús Ruiz-Contreras, Pepe Serrano Marchuet

“…The AEP 2025 Vaccination and Immunization Schedule recommended for children, adolescents and pregnant women residing in Spain features the following novelties:Due to the increase in measles cases and outbreaks in recent years, we recommend advancing the second dose of measles, mumps and rubella (MMR) vaccine to 2 years of age.As a consequence of the above, since many autonomous communities (ACs) use the quadrivalent vaccine for the second dose of MMR and varicella vaccines, we recommend, for all ACs, advancing the second dose of varicella vaccine to 2 years of age.Due to the very significant increase in cases of pertussis since late 2023 and especially in 2024, we recommend advancing the dose of Tdap given in adolescence to 10–12 years of age.To complete protection against meningococcal disease in adolescence, we recommend vaccination against MenB at age 12 years.We believe that vaccination against seasonal influenza should be routine up to age 18 years, but given the disappointing coverage in children aged 6–59 months, we currently consider that improving this coverage should be prioritised, extending vaccination to children and adolescents aged 5–18 years once this objective has been achieved.Among other aspects, the routine immunization tables for healthy individuals and risk groups, the use of the new extended-valence conjugate vaccines against pneumococcal disease, routine vaccination at 4 months of age with MenACWY and vaccination against SARS-CoV-2 for individuals aged more than 6 months with risk factors remain unchanged with respect to the 2024 schedule. …”
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Evaluation of IgG binding capability to SARS-CoV-2 variants in early COVID-19 convalescent sera using an indirect ELISA by Behzad Hussain, Peizhe Zhao, Yu Liu, Bo Yang, Xiaoxiong Li, Zhichao Zhang, Guoqiang Feng, Demei Zhang, Defen Lu, Wu Changxin

“…These results indicate that the patients recovering from natural infection of early original Wuhan strain may have the potential to resist infection of current circulating variants and the vaccines using the prototype antigen may still work for newly emerged variants.…”
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Individual and community level maternal factors for zero-dose children in Ethiopia using mini-EDHS 2019: a mixed effects model by Anteneh Kassa Yalew, Werkneh Melkie Tilahun, Meron Asmamaw Alemayehu, Tigabu Kidie Tesfie, Muluken Chanie Agimas, Mekuriaw Nibret Aweke, Worku Necho Asferie, Moges Tadesse Abebe

“…Introduction Zero-dose children refer to a child who has not yet received any childhood vaccines. Globally, zero-dose children are the major public health problem. …”
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The Mycoplasma hyopneumoniae protein Mhp274 elicits mucosal and systemic immune responses in mice by Mengqi Xie, Zhongshun Huang, Yun Zhang, Yujie Gan, Huiying Li, Dan Li, Honglei Ding

“…The bottleneck in the development of more effective vaccines for MPS is the stimulation of effective immune responses in the host. …”
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Cohort profile: the potentially preventable burden of community-acquired pneumonia in South African adults in the era of widespread PCV13 immunisation and antiretroviral therapy ro... by Jo Southern, Kennedy Otwombe, Eileen Dunne, Khuthadzo Hlongwane, Bradford D Gessner, Michelle Wong, Cheryl Cohen, Anne von Gottberg, Elizabeth Begier, Sharon Gray, Ebrahim Variava, Tumelo Moloantoa, Neil Martinson, Firdaus Nabeemeeah, Nadia Sabet, Lebohang M Mlambo, Phetho Mangena, Pattamukkil Abraham, Floris Swanepoel, Fahima Moosa, Mark Fletcher, Bha Ndungane-Tlakula, Jerusha Naidoo, Minja Milovanovic

“…Purpose In the setting of an established childhood pneumococcal vaccination programme with immediate initiation and treatment of antiretroviral therapy (ART) for people living with HIV (PLWH), the risk of adult pneumococcal community-acquired pneumonia (CAP) is not recently described. …”
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A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment by Sandra Viz-Lasheras, Alberto Gómez-Carballa, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Nina Schweintzger, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Ulrich Von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Henriëtte A. Moll, Clementien Vermont, Michael Levin, Federico Martinón-Torres, Antonio Salas, On behalf of EUCLIDS, PERFORM, and DIAMONDS consortia

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Transgenic Killer Commensal Bacteria as Mucosal Protectants by Luciano Polonelli

“…Unfortunately, current strategies for mucosal protection against candidiasis are severely limited by the lack of effective vaccines and the relative paucity and toxicity of commercially available antifungal drugs. …”
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Beyond Borders: Understanding the Role of Drones in Healthcare Services in India and Abroad by Ankita Sharma, Bhavna Rani

“…Drones have the potential to be reliable medical delivery platforms for microbiological and laboratory samples, pharmaceuticals, vaccines, emergency medical equipment and patient transport. …”
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