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1581
Advancements in Liposomal Nanomedicines: Innovative Formulations, Therapeutic Applications, and Future Directions in Precision Medicine
Published 2025-01-01“…The recent COVID-19 pandemic has accelerated research in liposomal-based vaccines and antiviral therapies, underscoring the need for improved delivery mechanisms to overcome challenges like rapid clearance and organ toxicity. …”
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1582
Evaluation of In-House ELISA for Antirabies Antibodies Detection in Domestic Canine
Published 2023-01-01“…Postvaccination monitoring should be carried out to evaluate the success of vaccination by measuring antibody titers in serum of vaccinated dogs. …”
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1583
Developing a taxonomy to describe offspring outcomes in studies involving pregnant mammals' exposure to non-tobacco nicotine: A systematic scoping review.
Published 2023-01-01“…We excluded studies that investigated exposure to only smoking, e-cigarettes, nicotine vaccines, or studies with no 'nicotine only' group. …”
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1584
Testing and identification of bovine viral diarrhea virus isolates recovered in Russia between 2019 and 2022
Published 2023-12-01“…Studying the agents of bovine viral diarrhea (BVD) is an important task given the high probability of new isolate introduction into the Russian Federation, as well as the need to take into account the genotype and subgenotype of the virus circulating in a herd when developing vaccines and diagnostic kits for the infection. During the work performed, 6 BVD virus isolates were recovered and identified. …”
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1585
Therapeutic development to accelerate malaria control through intentional intervention layering
Published 2025-01-01“…Abstract The clinical development of novel vaccines, injectable therapeutics, and oral chemoprevention drugs has the potential to deliver significant advancements in the prevention of Plasmodium falciparum malaria. …”
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1586
Influenza D virus in cattle (review)
Published 2024-03-01“…There are currently no vaccines or specific treatment for influenza D virus. …”
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1587
Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L
Published 2025-02-01“…Taken together, these results highlight the important role of DP71L with respect to inhibition of interferon responses and provide guidance for a better understanding of ASFV pathogenesis and the development of live attenuated ASFV vaccines.…”
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1588
Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges
Published 2025-01-01“…Multiple forms of cancer immunotherapy, including immune checkpoint inhibitors (ICIs), adoptive cell therapy and cancer vaccines, have become widely available. However, the effectiveness of these immunotherapies is not much satisfying. …”
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1589
Antihepatitis B Virus Activity of a Protein-Enriched Fraction from Housefly (Musca domestica) in a Stable HBV-Producing Cell Line
Published 2014-01-01“…Hepatitis B virus (HBV) infection remains a major public health problem. Although several vaccines and therapeutic strategies are currently being implemented to combat HBV virus, effective antiviral therapy against HBV infection has not been fully developed. …”
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1590
Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023
Published 2025-02-01“…Furthermore, continued research into vaccines and therapeutic drugs remains indispensable for augmenting public health outcomes.…”
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1591
Replication-transcription complex of coronaviruses: functions of individual viral non-structural subunits, properties and architecture of their complexes
Published 2022-04-01“…Severe acute respiratory syndrome CoV (SARS-CoV), Middle East respiratory syndrome CoV (MERS-CoV), and the novel coronavirus (2019-nCoV, SARS-CoV-2) have been identif ied as causing global pandemics. Clinically tested vaccines are widely used to control rapidly spreading, acute, and often severe infections; however, effective drugs are still not available. …”
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1592
STUDY ON THE ESTIMATION OF SARS-CoV-2 VIRUS PATHOGENS’ TRANSMISSION PROBABILITIES FOR DIFFERENT PUBLIC BUS TRANSPORT SERVICE SCENARIOS
Published 2023-09-01“…The study draws on scenarios from the first and second waves of the COVID-19 pandemic in Poland, a period that was devastatingly marked by the lack of available vaccines. This study aims to add value to the scientific community by offering an estimation of the likelihood of SARS-CoV-2 transmission in public transport and a preliminary risk assessment for COVID-19 infection, considering the number of active, non-isolated COVID-19 cases in the Polish population. …”
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1593
Experimental Immunization Based on Plasmodium Antigens Isolated by Antibody Affinity
Published 2015-01-01“…Vaccines blocking malaria parasites in the blood-stage diminish mortality and morbidity caused by the disease. …”
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1594
Scoping review of the applications of peptide microarrays on the fight against human infections.
Published 2022-01-01“…<h4>Conclusion</h4>The most important application of peptide microarrays was found to be B-cell epitope mapping or antibody profiling to identify diagnostic and vaccine targets. Immunosignatures identified by random peptide microarrays were found to be applied in the diagnosis of infections and interrogation of vaccine responses. …”
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1595
Calreticulin as an Adjuvant In Vivo to Promote Dendritic Cell Maturation and Enhance Antigen-Specific T Lymphocyte Responses against Melanoma
Published 2022-01-01“…Our results demonstrate that CRT/39-272 can be used as a potential new adjuvant for tumor vaccines, and this finding may be useful in tumor vaccine development.…”
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1596
Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis
Published 2021-01-01“…The epitopes identified here provide a foundation for the diagnosis and treatment of patients infected with drug resistant and the future development of a multiepitope vaccine.…”
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1597
Proline isomerization modulates the bacterial IsdB/hemoglobin interaction: an atomic force spectroscopy study
Published 2025-02-01“…Abstract Iron surface determinant B (IsdB), a Staphylococcus aureus (SA) surface protein involved in both heme iron acquisition from host hemoglobin (Hb) and bacterial adhesion, is a proven virulence factor that can be targeted for the design of antibacterial molecules or vaccines. Recent single-molecule experiments on IsdB interaction with cell adhesion factors revealed an increase of the complex lifetime upon applying a stronger force (catch bond); this was suggested to favor host invasion under shear stress. …”
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1598
Dengue severity by serotype and immune status in 19 years of pediatric clinical studies in Nicaragua.
Published 2025-01-01“…<h4>Conclusions</h4>These findings demonstrate differences in dengue severity by serotype and immune status and emphasize the critical need for a dengue vaccine with balanced effectiveness against all four serotypes, particularly as existing vaccines show variable efficacy by serotype and serostatus.…”
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1599
Sealless Production Ultracentrifuge and Its Magnetically Self-Bearing Openable Motors for Purification in Viral Nanotechnology
Published 2025-01-01“…Viral nanotechnology enables new possibilities for gene therapies and vaccines. However, the manufacturing of viral vectors lacks a satisfactory production capable method for purification of full capsids. …”
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1600
Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer
Published 2021-01-01“…To explore the possibility of combining targeted drugs with Th1-polarizing vaccines, we undertook a study to examine the impact of combining Th1 cytokines with the relatively broad-spectrum receptor tyrosine kinase antagonist, sunitinib. …”
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