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Retroviral and Lentiviral Vectors for the Induction of Immunological Tolerance
Published 2012-01-01“…They have been used for some time for gene therapy and the development of gene vaccines. Recently retroviral and lentiviral vectors have been used to generate tolerogenic dendritic cells, key professional antigen presenting cells that regulate immune responses. …”
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1562
Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model.
Published 2025-01-01“…<h4>Background</h4>Machupo virus (MACV) is a New World mammarenavirus (hereafter referred to as "arenavirus") and the etiologic agent of Bolivian hemorrhagic fever (BHF). No vaccine or antiviral therapy exists for BHF, which causes up to 35% mortality in humans. …”
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1563
Seroprevalence Study of Dengue at a Tertiary Care Hospital in Jaipur, Rajasthan
Published 2024-05-01“…In the absence of specific treatments and vaccines for dengue fever (DF), vector control is the only method by which the spread of dengue can be prevented. …”
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1564
The Efforts to Implement a Malaria Elimination Strategy in The Highly Endemic Malaria Region of Papua Province, Indonesia
Published 2024-10-01“…Indonesia has recently completed a malaria vaccine trial, the IDSPZV1, which included the PfSPZ Vaccine and PfSPZ-CVac (CQ), conducted among soldiers deployed to Papua Province, New Guinea, for 10 months. …”
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1565
Multiple outbreaks for the same pandemic: Local transportation and social distancing explain the different 'waves' of A-H1N1pdm cases observed in México during 2009
Published 2010-12-01“…The limited impact of the late arrival of the vaccine is also analyzed.…”
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1566
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1567
4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets
Published 2025-01-01“…At the moment, there are neither approved vaccines nor effective drugs for the treatment of human leishmaniasis for any of its three typical clinical manifestations, and, importantly, the drugs of clinical use have several side effects, require complex administration regimens, present high cost, and are ineffective in many populations due to pathogen resistance. …”
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1568
Changes in the Profile of Antibiotic Prescriptions by Dentists in Brazil during the Pandemic
Published 2022-01-01“…During the COVID-19 pandemic, people worldwide, including the scientific community, were insecure and fearful. The lack of vaccines at the beginning of the pandemic and the high mortality rate led to a search for alternative treatments for COVID-19. …”
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1569
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Single cell RNA sequencing improves the next generation of approaches to AML treatment: challenges and perspectives
Published 2025-01-01“…Generated data of the transcriptional profile of the AML could even allow the development of cancer vaccines and CAR T-cell therapies while saving valuable time and alleviating dangerous side effects of chemotherapy and HSCT in vivo. …”
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1571
A lyophilised formulation of chimpanzee adenovirus vector for long-term stability outside the deep-freeze cold chain
Published 2025-01-01“…Abstract Background The adenovirus-vaccine platform has come to prominence with the COVID-19 vaccination campaigns. …”
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1572
Method of obtaining and storing hyperimmune anthrax serum
Published 2023-09-01“…A live culture of Bacillus anthracis 55-VNIIVViM vaccine strain, used to produce live vaccines against animal anthrax, was used in the experiments. …”
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1573
Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy
Published 2025-02-01“…MAGEA4-based TCR-T cell therapy and cancer vaccines show clinical potential. This article comprehensively reviews the structure and function of MAGEA4, as well as recent research progress in solid tumors, providing a theoretical foundation for the clinical translation of MAGEA4 and its application in immunotherapy.…”
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1574
Confidence intervals for the COVID-19 neutralizing antibody retention rate in the Korean population
Published 2020-09-01“…No specific therapeutic agents or vaccines for COVID-19 are available, though several antiviral drugs, are under investigation as treatment agents for COVID-19. …”
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1575
Multi-target and natural product-based multi-drug approach for anti-VEGF resistance in glioblastoma
Published 2024-09-01Get full text
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1576
Effect of attenueted parapoxvirus ovis on levels of some serum cytokines and antibody response in sheep
Published 2022-06-01“…<p> <b>Conclusion:</b> It was concluded that the vaccines against ORFV infection considered to be used in the future should be applied after the effects on the immune system have been clearly demonstrated.…”
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1577
Analysis of the Complete Genomes of Enterovirus 71 Subtypes in China
Published 2021-01-01“…This study indicated that the major C4 and B5 subtypes will contribute to the development of vaccines and drugs of EV-A71 for prevention and monitoring of EV-A71-associated HFMD in China.…”
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1578
Recombinant XBB.1.5 boosters induce robust neutralization against KP.2- and KP.3-included JN.1 sublineages
Published 2025-01-01“…We further investigated humoral immune response of recombinant XBB vaccines against Omicron variants and estimated the neutralization resistance of JN.1 sublineages, including KP.2 and KP.3. …”
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Chiral polypeptide hydrogels regulating local immune microenvironment and anti-tumor immune response
Published 2025-01-01“…Abstract The impact of chirality on immune response has attracted great interest in cancer vaccine research recently. However, the study of chiral synthetic polypeptide hydrogels as cancer vaccines as well as of the impact of biomaterials themselves for antitumor immunotherapy has rarely been reported. …”
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