Gene Carriers and Transfection Systems Used in the Recombination of Dendritic Cells for Effective Cancer Immunotherapy by Yu-Zhe Chen, Xing-Lei Yao, Yasuhiko Tabata, Shinsaku Nakagawa, Jian-Qing Gao

“…Reported research in animal studies indicated that vaccine immunity could be a promising alternative therapy for cancer patients. …”
Get full text

Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation. by Louis Kuijpers, Evdokia-Anastasia Giannopoulou, Yuzhen Feng, Wouter van den Braak, Abbas Freydoonian, Ramon Ramlal, Hugo Meiring, Belén Solano, Wouter H Roos, Arjen J Jakobi, Leo A van der Pol, Nynke H Dekker

“…To counteract hand, foot, and mouth disease-causing viruses such as enterovirus A71 and coxsackievirus A6, virus-like particles (VLPs) have emerged as a leading contender for the development of a multivalent vaccine. However, VLPs have shown rapid conversion from a highly immunogenic state to a less immunogenic state and low particle integrity lifetimes compared to inactivated virus vaccines, thus raising concerns about their overall stability. …”
Get full text

Induced protein expression in Leptospira spp. and its application to CRISPR/Cas9 mutant generation by L. G. V. Fernandes, A. L. T. O. Nascimento, J. E. Nally

“…These newly controlled protein expression systems will advance studies on the basic biology and virulence of Leptospira, as well as facilitate knockout mutant generation for improved veterinary vaccines.…”
Get full text

Bioterrorism in Canada: An Economic Assessment of Prevention and Postattack Response by Ronald St John, Brian Finlay, Curtis Blair

“…Rapid implementation of a postattack prophylaxis program that includes the stockpiling of antibiotics, vaccines and antitoxins; training of first responders in the diagnosis, handling and treatment of pathogens; and the general enhancement of Canada's response capability would reduce both human and economic losses.…”
Get full text

Beyond immortality: Epstein–Barr virus and the intricate dance of programmed cell death in cancer development by Arezoo Esmaeili, Prankur Awasthi, Samira Tabaee

“…Furthermore, the insights gleaned from this review could catalyze the design of vaccines aimed at preventing EBV infection or curtailing its oncogenic impact. …”
Get full text

SPREAD OF LOW PATHOGENIC AVIAN INFLUENZA А/Н9N2 IN THE WORLD AND RUSSIAN FEDERATION. CHALLENGES OF DISEASE ERADICATION by M. S. Volkov, A. V. Varkentin, V. N. Irza

“…Н9 virus circulation is reflected not only in the physical condition of birds and their productivity, but it also affects the live vaccines’ efficacy during scheduled immunizations through the reduction of their protective effect and increase of post-vaccination reactions. …”
Get full text

In Silico Study of Alkaloids: Neferine and Berbamine Potentially Inhibit the SARS-CoV-2 RNA-Dependent RNA Polymerase by Rishab Marahatha, Asmita Shrestha, Kabita Sharma, Bishnu P. Regmi, Khaga Raj Sharma, Pramod Poudel, Ram Chandra Basnyat, Niranjan Parajuli

“…While there have been some vaccines and drugs, the rapid emergence of variants due to mutations has threatened public health. …”
Get full text

COVID-19 and the Medical Devices in India: Trade for a Resilient Health System by Ravinder Jha, Diwas Saun, Indrani Gupta

“…The COVID-19 pandemic exposed a lack of resilience in areas of drugs and vaccines but also in medical products. Objectives: The study analyzes India’s strengths and weaknesses in the trade of medical devices and identifies specific devices where India can attain self-sufficiency and areas where trade is still beneficial. …”
Get full text

Quinoline and Quinazoline Alkaloids against COVID-19: An In Silico Multitarget Approach by Esraa M. O. A. Ismail, Shaza W. Shantier, Mona S. Mohammed, Hassan H. Musa, Wadah Osman, Ramzi A. Mothana

“…Although, recently, vaccines have been approved for the prevention of COVID-19, there is still an urgent need for the discovery of more efficacious and safer drugs especially from natural sources. …”
Get full text

Characterization of environmental and clinical surveillance inputs to support prospective integrated modeling of the polio endgame. by Kamran Badizadegan, Kimberly M Thompson

“…Relatively recently, the GPLN expanded to include environmental surveillance to obtain additional information about poliovirus transmission in some geographies and to increase confidence about the absence of poliovirus transmission after successful eradication and/or the cessation of use of live-attenuated oral poliovirus vaccines (OPVs). Historical polio eradication strategic plans anticipated that successful global poliovirus eradication would lead to reduced requirements for financial investments for a poliovirus-specific surveillance system, and consequent transition of capacity and resources into integrated national disease surveillance systems. …”
Get full text

Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals by Ghyda Murad Hashim, Mehdi Shahgolzari, Kathleen Hefferon, Afagh Yavari, Srividhya Venkataraman

“…Also addressed are plant-derived anti-cancer vaccines, nanoparticles, monoclonal antibodies, and immunotherapies. …”
Get full text

The Immune Response to Tumors as a Tool toward Immunotherapy by F. Pandolfi, R. Cianci, D. Pagliari, F. Casciano, C. Bagalà, A. Astone, R. Landolfi, C. Barone

“…Immunotherapy of tumors has developed several techniques: immune cell transfer, vaccines, immunobiological molecules such as monoclonal antibodies that improve the immune responses to tumors. …”
Get full text

Natural compounds from medicinal plants against COVID-19 by Anton Kolodnitsky, Nikita Ionov, Irina Gravel, Vladimir Poroikov

“…Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. …”
Get full text

RISK OF INTRODUCING HIGHLY DANGEROUS ANIMAL VESICULAR DISEASES INTO THE RUSSIAN FEDERATION by V. P. Semakina, T. P. Akimova, I. Yu. Solomatina, A. K. Karaulov

“…The transboundary spread of vesicular diseases is mainly caused by legal and illegal movements of animals, animal products, feeds, live vaccines; migration of wild animals across the borders from neighboring countries and passive mechanical transmission of infection. …”
Get full text

Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses by Tamana Eskandari, Yasamin Eivazzadeh, Fatemeh Khaleghinia, Fatemeh Kashi, Valentyn Oksenych, Dariush Haghmorad

“…These advancements have paved the way for lipid-based vaccines and immunotherapies through the application of nanoparticles and synthetic lipid antigens designed to boost immune responses against cancers and infectious diseases. …”
Get full text

Cleaner Production Quality Regulation Strategy of Pharmaceutical with Collusive Behavior and Patient Feedback by Junmei Rong, Lilong Zhu

“…However, the various types of counterfeit pharmaceuticals and fake vaccines exposed in the recent years have revealed many problems, such as lacking government regulation, loose quality management of companies, illegal profit of medical service agencies, and failure of patient complaints. …”
Get full text

Meta-Analysis of Pulmonary Transcriptomes from Differently Primed Mice Identifies Molecular Signatures to Differentiate Immune Responses following Bordetella pertussis Challenge by René H. M. Raeven, Jeroen L. A. Pennings, Elly van Riet, Gideon F. A. Kersten, Bernard Metz

“…Complement-mediated responses were more prominent in mice immunized with an outer membrane vesicle pertussis vaccine than in mice that received a whole-cell pertussis vaccine. …”
Get full text

Comparison of β-Propiolactone and Formalin Inactivation on Antigenicity and Immune Response of West Nile Virus by Pritom Chowdhury, Rashmee Topno, Siraj A. Khan, Jagadish Mahanta

“…Till now there are no approved vaccines against WNV for human use. In this study, the effect of two alkylating agents, formaldehyde and β-PL, generally used for inactivated vaccine preparation, was assessed on the basis of antigenic and immunogenic potential of the inactivated WNV. …”
Get full text

Post-pandemic insights on COVID-19 and premature ovarian insufficiency by Han Yaguang, Dai Yang, Wang Kexin, Zhang Xin, Shao Zishen, Zhu Xiaolin

“…Vaccines could mitigate the severity of COVID-19’s impact on ovarian function, while isolation may reduce stress and inflammation. …”
Get full text

The JN.1 variant of COVID-19: immune evasion, transmissibility, and implications for global health by Araj Naveed Siddiqui, Imshaal Musharaf, Bashar Haruna Gulumbe

“…It is essential to encourage the public to maintain vaccination and preventive measures to reduce JN.1’s impact. …”
Get full text