The Model of PPARγ-Downregulated Signaling in Psoriasis by Vladimir Sobolev, Anastasia Nesterova, Anna Soboleva, Evgenia Dvoriankova, Anastas Piruzyan, Dzerassa Mildzikhova, Irina Korsunskaya, Oxana Svitich

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Life Science 2.0: reframing the life science sector for ‘the benefit on mankind’ by Michaela Vallin, Göran Tomson, Beate Kampmann, Eivind Engebretsen, Stefan Swartling Peterson, Rhoda K. Wanyenze, Ole Petter Ottersen

“…The COVID-19 pandemic put the life science sector to the test. Vaccines were developed at unprecedented speed, benefiting from decades of fundamental research and now honoured by a Nobel Prize. …”
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The Beneficial Effect of IL-12 and IL-18 Transduced Dendritic Cells Stimulated with Tumor Antigens on Generation of an Antitumor Response in a Mouse Colon Carcinoma Model by Jagoda Mierzejewska, Katarzyna Węgierek-Ciura, Joanna Rossowska, Agnieszka Szczygieł, Natalia Anger-Góra, Bożena Szermer-Olearnik, Magdalena Geneja, Elżbieta Pajtasz-Piasecka

“…Application of the developed DC-based vaccines may exert a favorable impact on stimulation of an antitumor immune response, especially if these DC vaccines are administered repeatedly.…”
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Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent by V. A. Graham, G. J. Hatch, K. R. Bewley, K. Steeds, A. Lansley, S. R. Bate, S. G. P. Funnell

“…This allows licensure of drugs and vaccines using protection data generated in animal models. …”
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Médecines créoles guyanaise et haïtienne face au Covid-19 by Marc-Alexandre Tareau, Guillaume Odonne

“…Contrary to the usual pluralism, a strong cleavage between biomedicine and local herbal medicine was noted, and in particular a significant distrust of vaccines by the Creole population. This opposition has largely materialized in the form of a communitarianism of « them » against « us », « their vaccine » against « our plants ». …”
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Deep learning-based malaria parasite detection: convolutional neural networks model for accurate species identification of Plasmodium falciparum and Plasmodium vivax by Diego A. Ramos-Briceño, Alessandro Flammia-D’Aleo, Gerardo Fernández-López, Fhabián S. Carrión-Nessi, David A. Forero-Peña

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Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants by Susana Martiñón, Angel Cisneros, Sergio Villicaña, Ricardo Hernández-Miramontes, Edgar Mixcoha, Psyché Calderón-Vargas

“…Adjuvants are a diverse family of substances whose main objective is to increase the strength, quality, and duration of the immune response caused by vaccines. The most commonly used adjuvants are aluminum-based, oil-water emulsion, and bacterial-origin adjuvants. …”
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A New Experimental Infection Model in Ferrets Based on Aerosolised Mycobacterium bovis by Lyanne McCallan, David Corbett, Peter L. Andersen, Claus Aagaard, David McMurray, Claire Barry, Suzan Thompson, Samuel Strain, Jim McNair

“…There is significant interest in developing vaccines to control bovine tuberculosis, especially in wildlife species where this disease continues to persist in reservoir species such as the European Badger (Meles meles). …”
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Bovine Genital Campylobacteriosis by Max B. Irsik, Jan K. Shearer

“…Shearer, DVM, MS, describes this venereal disease of cattle formerly known as vibriosis, clinical findings and epidemiology, how to determine if there is a campylobacter problem in a herd, and the use of vaccines. Published by the UF Department of Veterinary Medicine -- Large Animal Clinical Sciences, March 2007. …”
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Immunology and the Central Nervous System by Carlos Barcia, James Curtin, Jeffrey Zirger, Daniel Larocque

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A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia by Sandra Viz-Lasheras, Alberto Gómez-Carballa, Jacobo Pardo-Seco, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Cristina Calvo, María del Carmen Martínez-Padilla, Ana Pérez-Aragón, Esteban Gómez-Sánchez, Juan Valencia-Ramos, Francisco Giménez-Sánchez, Paula Alonso-Quintela, Laura Moreno-Galarraga, Ulrich von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Clementien L. Vermont, Henriëtte A. Moll, Michael Levin, Federico Martinón-Torres, Antonio Salas

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New Insights for Immune-Based Diagnosis and Therapy for Infectious Diseases by Giuseppe A. Sautto, Roberta A. Diotti, Karin Wisskirchen, Kristen M. Kahle

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Q Fever: Current State of Knowledge and Perspectives of Research of a Neglected Zoonosis by Sarah Rebecca Porter, Guy Czaplicki, Jacques Mainil, Raphaël Guattéo, Claude Saegerman

“…However, inactive whole-cell vaccines present several defects. Recombinant vaccines have been developed in experimental conditions and have great potential for the future. …”
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Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies. by Peter R McIlroy, Le Thanh Mai Pham, Thomas Sheffield, Maxwell A Stefan, Christine E Thatcher, James Jaryenneh, Jennifer L Schwedler, Anupama Sinha, Christopher A Sumner, Iris K A Jones, Stephen Won, Ryan C Bruneau, Dina R Weilhammer, Zhuoming Liu, Sean Whelan, Oscar A Negrete, Kenneth L Sale, Brooke Harmon

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to persist, demonstrating the risks posed by emerging infectious diseases to national security, public health, and the economy. Development of new vaccines and antibodies for emerging viral threats requires substantial resources and time, and traditional development platforms for vaccines and antibodies are often too slow to combat continuously evolving immunological escape variants, reducing their efficacy over time. …”
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Attitudes of Final-Year Medical Students in Jordan Towards Volunteering During a Pandemic by Alassaf A, Gharaibeh L, Alkubaisi F, Alkhawaldeh M, Dababseh S, Odeh R

“…Around 60% of students were willing to participate in future voluntary work that does not involve patients infected with COVID-19, while 29.3% of them were willing to do so depending on the type of pandemic and the availability of vaccines. There were 86.1% of students who thought that participating in voluntary work involving infected patients during pandemics, should be optional; where 10.1% suggested that it should be compulsory if vaccines were available.Conclusion: The majority of medical students did not volunteer during the COVID 19 pandemic. …”
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Immunological Responses and Epitope Mapping by Tuberculosis-Associated Antigens within the RD1 Region in Japanese Patients by Hideaki Nagai, Maho Suzukawa, Yumi Sakakibara, Ken Ohta, Pedro A. Reche, Koichi Suzuki, Yoshihiko Hoshino

“…Tuberculosis remains a major global health problem worldwide, and hence there is a need for novel vaccines that better induce cellular-mediated immunity (CMI). …”
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Exploring Strategies to Improve Adherence to Immunization Schedule: A Study among Children Attending Maternal and Child Health Clinic at Kenyatta National Hospital, Nairobi, Kenya by Esther Cheptanui Muathe, Mary Kamau, Eve Rajula

“…The highest fatality rates from vaccine preventable diseases are usually among children under five. …”
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The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 by Lingxian Qiu, Wenting Luo, Youlan Chen, Zhinan Guo, Jiali Quan, Jiahuang Chi, Yingying Guan, Yue Huang, Yilan Lin

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Recent advances of nanovaccines on cancer theranostics by Xiaobing Yuan, Xiaobing Yuan, Xiaobing Yuan, Tianyou Xu, Mubashir Hussain, Bin Liu, Jianwei Zhu, Jianwei Zhu

“…This paper reviewed the research progress of some nanovaccines in cancer immunotherapy, including polymer nanoparticle vaccine, liposome nanoparticle vaccine, cell-based nanoparticle vaccine, inorganic nanoparticle vaccine, adjuvant and auxiliary work. …”
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Impact of non-pharmacological interventions on the first wave of COVID-19 in Portugal 2020 by Dinis B. Loyens, Constantino Caetano, Carlos Matias-Dias

“…Introduction: The COVID-19 pandemic caused over 7 million global deaths. Without vaccines during the first wave, governments implemented nonpharmacological interventions (NPIs) such as lockdowns, school closures, and travel restrictions. …”
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