Rapid aging of influenza epidemics in China from 2005/06 to 2016/17: A population-based study by Weibo Tang, Hao Lei, Nan Zhang, Yaojing Wang, Shimeng Cai, Shuyi Ji, Lei Yang, Mengya Yang, Can Chen, Shigui Yang, Dayan Wang, Yuelong Shu

“…This finding highlights the importance of influenza vaccination among older individuals in China.…”
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Genetic proxies for clinical traits are associated with increased risk of severe COVID-19 by N. J. M. Chaddock, S. S. R. Crossfield, M. Pujades-Rodriguez, M. M. Iles, A. W. Morgan

“…PRS were optimized for 23 clinical variables and related traits previously-associated with severe COVID-19 in up to 450,449 UK Biobank participants, and tested in 9,560 individuals diagnosed in the pre-vaccination era. Associations were further adjusted for (i) sociodemographic and (ii) clinical variables. …”
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Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen by Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

“…Our study suggests a temporal window soon after BCG vaccination, in which STAT1-dependent activation of long-lived resident cells in the tissue mediates localized protection.…”
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A scoping review of transmission models for soil-transmitted helminth infections to underpin the development of a transmission model for Strongyloides stercoralis by Mackrina Winslow, Juan Pablo Villanueva-Cabezas, Vito Colella, Patricia T. Campbell

“…Models were frequently used to simulate the effectiveness of mass drug administration, including drug efficacy and treatment coverage, while water, sanitation, and hygiene (WASH), health education, and vaccination were less explored. Given the limitation of individual-level data, compartmental models may be a reasonable starting point for S. stercoralis transmission. …”
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Performance of a Point-of-Care Test Kit (Anigen Rapid^®) to Diagnose Feline Immunodeficiency Virus (FIV) Infection in Domestic Cats Using Saliva Instead of Blood in Austr... by Jennifer Green, Adele Scannell, Evelyn Hall, Mark E. Westman

“…This study proves the ability to utilise cheap and readily available consumables for less invasive FIV testing purposes by using saliva instead of blood, for example, when screening cat before adoption in shelters and in cats prior to annual FIV re-vaccination.…”
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Avian colibacillosis – current aspects by A. O. Gerasimova, O. B. Novikova, A. A. Savicheva

“…Colibacillosis prevention includes improvement of poultry keeping practice (control of feed and water quality, disinfection, pest control, microclimate control) as well as timely complex vaccination of all poultry. The disease shall be treated taking into account primary etiological factors and bacteria sensitivity to antimicrobials.…”
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Some of the applications level of the protection and control of mastitis in dairy cattle farms in turkey with different qualifications by Ali Rişvanlı, Nevzat Saat, Tarık Şafak, Öznur Yılmaz, Burak Fatih Yüksel, Mehmet Akif Kılınç, Halef Doğan, Murat Yüksel, Selim Kul, İbrahim Şeker

“…It was determined that the applications of teat dipping (70.4%), dry period antibiotics (72.8%), teat seal (9.5%) and mastitis vaccine (55.6%) in large farms were higher than small scale farms and It was determined that the proportion of those which do predipping and postdipping is higher than those which do not, and that iodine antiseptics are used the most in applications. …”
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Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England by Pablo N. Perez-Guzman, Edward Knock, Natsuko Imai, Thomas Rawson, Cosmo Nazzareno Santoni, Joana Alcada, Lilith K. Whittles, Divya Thekke Kanapram, Raphael Sonabend, Katy A. M. Gaythorpe, Wes Hinsley, Richard G. FitzJohn, Erik Volz, Robert Verity, Neil M. Ferguson, Anne Cori, Marc Baguelin

“…We quantified the impact of non-pharmaceutical interventions (NPIs), therapeutics, and vaccination on virus transmission and severity. Each successive variant had a higher intrinsic transmissibility. …”
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Features and Functionalities of Medical Mobile Applications for the Endemic Phase of COVID‐19: Review and Content Analysis by Mei Jun Loy, Khang Wen Goh, Norliza Osili, Long Chiau Ming, Jagjit Singh Dhaliwal, Andi Hermansyah, Yaser Mohammed Al-Worafi, Kah Seng Lee

“…Functionality assessment wise, 79.3% included information regarding COVID-19, 12.1% included COVID-19 contact tracing, 17.2% had vaccination status, a health authority maintained 50%, 31.0% included COVID-19 statistics, and 25.8% were able to report ART/PCR test. …”
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Assessment of knowledge and practices of exclusive breastfeeding among rural women during the COVID-19 pandemic in Egypt: a cross sectional study by Noura El-Gamel, Amina El-Nemer

“…A total of 98.3% of rural women had never made skin-to-skin contact, and 79.2% of them had not been vaccinated against COVID-19. Additionally, a statistically significant association between good knowledge and practice with highly educated women aged 26–30 years, with a monthly income of 4000–6000 L.E was found. …”
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Preparation of a Novel ACS/CS/EDTA Composite from Sugarcane Bagasse for Enhanced Adsorption of Carbon Dioxide by Quang Minh Pham, Xuan Son Nghiem, Thang Le Minh, Anh-Tuan Vu

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Anti-Tn Monoclonal Antibody Ameliorates Hyperoxia-Induced Kidney Injury by Suppressing Oxidative Stress and Inflammation in Neonatal Mice by Julie Chi Chow, Hsiu-Chu Chou, Jaulang Hwang, Chung-Ming Chen

“…Maternal immunization with the Tn vaccine increases serum anti-Tn antibody titers and attenuates hyperoxia-induced kidney injury in neonatal rats. …”
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Mycophenolate mofetil: an update on its mechanism of action and effect on lymphoid tissue by Anna Krawczyk, Bernard Kravčenia, Tomasz Maślanka

“…The study demonstrated the following actions of the drug: (a) proapoptotic action on effector CD4+ and CD8+ T (Teff) cells, and B cells; (b) the down-regulation or prevention of activation-induced expression of CD25 on CD4+ and CD8+ Teff cells; (c) the generation of Foxp3+CD25+CD4+ and Foxp3+CD25+CD8+ T cells resulting in the shift of the Treg cell/activated Teff cell balance toward an increased proportion of Treg cells.ConclusionThe depletive effect of MMF on CD4+ and CD8+ T cells and B cells in lymphoid tissues should be taken into account when assessing the benefit-risk ratio of using MMF in patients with microbial infections and undergoing vaccination. The study contributed new insight into this mechanism, indicating that MMF effectively prevents the proliferation of T and B cells, but may be less effective against already proliferating cells. …”
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A vicious cycle of frailty and acute lower respiratory infection among community-dwelling adults (≥ 60 years): Findings from a multi-site INSPIRE cohort study, India. by Siddhartha Saha, Ritvik Amarchand, Rakesh Kumar, Aslesh O Prabhakaran, Prabu Rajkumar, Sumit Dutt Bhardwaj, Suman Kanungo, Radhika Gharpure, Kathryn E Lafond, Eduardo Azziz-Baumgartner, Anand Krishnan

“…The association between ALRIs and worsened frailty suggests prevention of ALRIs through vaccination and other strategies may have broad reaching health benefits for older adults.…”
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A review of emerging techniques for pyrethroid residue detection in agricultural commodities by Dirong Goh, Ahmad Faizal Abdull Razis, Nor Azah Yusof, Norida Mazlan, Noordiana Nordin, Choo Yee Yu

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Pediatric Sickle Cell Disease in Sudan: Complications and Management by Meysaa Talha, Bashier Osman, Safa Abdalla, Hind Mirghani, Iman Abdoon

“…Prophylactic penicillin was prescribed for 15% of patients, and 41.1% were immunized with pneumococcal vaccine (PPSV23). Most patients had been scheduled for planned follow-up visits every 3–6 months (93.2%). …”
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Urban Dealing with Pandemic: Comparative Responses on Spanish Flu and the Covid-19 Era in Indonesia by Pulung Sumantri, Ahmad Muhajir, Taslim Batubara

“…The emphasized responses are specific on countermeasures and vaccination programs during the Spanish Flu 1918 and Covid-19 pandemics. …”
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The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review by Asma D. Alshammari, Mona Matar Aldhafeeri, Amal M. Aldhafeeri, Maram Asaad Alanzi, Maha Bandar Almutairi, Jawaher Abdullah Alrasheedi, Thikra Adel Alsurur, Aeshah Dhahawi Alshammri

“…Additionally, it is important to administer vaccinations for specific pathogens (such as pneumococcal, herpes zoster, and influenza) before and during treatment. …”
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Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression by Juan Du, Ruyun Liu, Lin Ma, Yue Liu, Wei Wei, Ning Liu, Qiuhua Cao, Jianqiang Yu

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An Overview on The Pandemic Coronavirus Disease 2019 (COVID-19) Outbreak by Mariwan Abdulla Hama Salih

“…At the moment nothing can stop the virus from spreading, neither vaccine nor medicines were found to stop the virus and secure life of people of the planet.  …”
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