Research Progress of Fuzheng Jiedu Huayu Method in Reducing Toxicity and Enhancing Efficacy of Immunotherapy by Yufan CHEN, Sicong LI, Yiyuan CUI, Li FENG

“…Immunotherapy, including immune checkpoint inhibitors, tumor vaccine therapy, oncolytic virotherapy, and adoptive cell therapy, has made remarkably breakthroughs in the field of oncology. …”
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Different Transcriptional Profiles of Human Monocyte-Derived Dendritic Cells Infected with Distinct Strains of Mycobacterium tuberculosis and Mycobacterium bovis Bacillus Calmette-... by Nunzia Sanarico, Alessia Colone, Manuela Grassi, Viviana Speranza, Daniela Giovannini, Antonio Ciaramella, Vittorio Colizzi, Francesca Mariani

“…In order to analyze dendritic cells (DCs) activation following infection with different mycobacterial strains, we studied the expression profiles of 165 genes of human monocyte-derived DCs infected with H37Rv, a virulent Mycobacterium tuberculosis (MTB) laboratory strain, CMT97, a clinical MTB isolate, Mycobacterium bovis bacillus Calmette-Guérin (BCG), Aventis Pasteur, and BCG Japan, both employed as vaccine against tuberculosis. The analysis of the gene expression reveals that, despite a set of genes similarly modulated, DCs response resulted strain dependent. …”
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Camel milk is a neglected source of brucellosis among rural Arab communities by Peter Holloway, Matthew Gibson, Tanja Holloway, Iain Pickett, Brittany Crook, Jacqueline M. Cardwell, Stephen Nash, Imadidden Musallam, Bilal Al-Omari, Ahmad Al-Majali, Wail Hayajneh, Ehab Abu-Basha, Punam Mangtani, Javier Guitian

“…Control is largely via vaccination of small ruminant and cattle populations. …”
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The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet—Remaining Challenges in Hepatitis C by Nicholas van Buuren, Lorraine Fradette, Jason Grebely, Alexandra King, Mel Krajden, Sonya A. MacParland, Alison Marshall, Sahar Saeed, Joyce Wilson, Marina B. Klein, Selena M. Sagan

“…Comprehensive prevention strategies, including enhanced harm reduction, broader screening, widespread treatment, and vaccine development, are far from being realized. …”
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Expression of Proinflammatory and Regulatory Cytokines via NF-κB and MAPK-Dependent and IFN Regulatory Factor-3-Independent Mechanisms in Human Primary Monocytes Infected by Mycob... by Elena Giacomini, Maria Elena Remoli, Marta Scandurra, Valérie Gafa, Manuela Pardini, Lanfranco Fattorini, Eliana M. Coccia

“…Thus, by inducing a specific cytokine profile, Mtb can influence the immunoregulatory properties of monocytes, which represent important target of novel vaccinal strategies against Mtb infection.…”
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Local and Systemic Antibody Responses in Humans with Helicobacter pylori Infection by Thomas G Blanchard, John G Nedrud, Steven J Czinn

“…These studies suggest that the success of antihelicobacter immunization may be due to the ability of vaccination to induce an immune response against antigens that are normally not immunodominant during the course of infection.…”
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Batavia in Crisis: Disease Outbreaks and Public Health Responses in the 20th Century by Wisnu Rega Aditiya, Endang Susilowati, Dewi Yuliati

“…However, the introduction of mass vaccination programs in the 1910s and 1920s marked a turning point, demonstrating the potential of public health interventions in mitigating disease outbreaks. …”
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An HPLC-based Assay to Study the Activity of Cyclic Diadenosine Monophosphate (C-di-AMP) Synthase DisA from Mycobacterium smegmatis by Avisek Mahapa, Sudhanshu Gautam, Arti Rathore, Dipankar Chatterji

“…Additionally, c-di-AMP demonstrates potent adjuvant properties, particularly when administered alongside the Bacillus Calmette–Guérin (BCG) vaccine through mucosal routes. Because of its pivotal role in bacterial signaling and host immune response, this molecule has garnered significant interest from the pharmaceutical industry. …”
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Passive Protection of Diabetic Rats with Antisera Specific for the Polysaccharide Portion of the Lipopolysaccharide Isolated from Pseudomonas pseudomallei by Larry E Bryan, Sallene Wong, Don E Woods, David AB Dance, W Chaowagul

“…The wide distribution of the polysaccharide antigen among isolates of P pseudomallei used in this study and the protective role of antibody to the conjugated polysaccharide antigen suggest potential as a vaccine.…”
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Optimal control of chikungunya disease: Larvae reduction, treatment and prevention by Djamila Moulay, M. A. Aziz-Alaoui, Hee-Dae Kwon

“…Three main efforts are considered in order to limit the virus transmission. Indeed, there is no vaccine nor specific treatment against chikungunya, that is why the main measures to limit the impact of such epidemic have to be considered. …”
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Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting by Sofiia N. Rizatdinova, Alina E. Ershova, Irina V. Astrakhantseva

“…Such tools facilitated the search for potential therapeutic agents and accelerated epidemiological studies on post-infection and post-vaccination humoral immunity. This review focuses on the use of pseudoviruses as a model for large-scale applications to study enveloped viruses.…”
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Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review by Maria Eleonora Bizzoca, Stefania Leuci, Michele Davide Mignogna, Eleonora Lo Muzio, Vito Carlo Alberto Caponio, Lorenzo Lo Muzio

“…To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. …”
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In situ-formed cryomicroneedles for intradermal cell delivery by Mengjia Zheng, Tianli Hu, Yating Yang, Xuan Qie, Huaxin Yang, Yuyue Zhang, Qizheng Zhang, Ken-Tye Yong, Wei Liu, Chenjie Xu

“…As a proof-of-concept, we examined the loading and intradermal delivery of three cell types in clinically relevant in vitro and in vivo models, including mesenchymal stem cells for wound healing, melanocytes for vitiligo treatment, and antigen-pulsed dendritic cells for cancer vaccination.…”
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Virulence and pathogenicity of group B Streptococcus: Virulence factors and their roles in perinatal infection by Christina J. Megli, Sophia M. Carlin, Elizabeth J. Giacobe, Gideon H. Hillebrand, Thomas A. Hooven

“…We conclude by addressing current efforts in vaccine development, underscoring the need for effective prevention strategies against this pervasive pathogen.…”
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Evaluation of the Primary Healthcare attributes in a municipality located in the countryside of São Paulo State – Brazil by Lislaine Aparecida Fracolli, Marianne Junko Muramatsu, Maria Fernanda Pereira Gomes, Fabiana Rodrigues Zequini Nabão

“…Proper adaptations should be performed during the opening hours of the healthcare centers; facilitating access and appointment scheduling; improve the counter-reference and reference system; offer vaccination and stitch services; and also, improve the communication between professionals and users, review and reformulate the attendance model of the FHS…”
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National Consensus for the Management of Acute Gastroenteritis in Jordanian Children: Consensus Recommendations Endorsed by the Jordanian Paediatric Society by Mohammed Rawashdeh, Basim Al-Zoubi, Maha Barbar Aliwat, Salma Burayzat, Esam Alhindawi, Ali Attia Al-Matti, Eyad Altamimi

“…The prevention of diarrhoeal diseases should focus on the improvement of nutrition, hygiene, and sanitation, the introduction of routine vaccination against rotavirus, and the adoption of a standardised approach for AGE management (oral rehydration solution (ORS) use±adjunct therapies, continued feeding, and avoiding routine antibiotic use). …”
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Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease by Helen C. Steel, Riana Cockeran, Ronald Anderson, Charles Feldman

“…Despite the implementation of national pneumococcal polyvalent vaccine-based immunisation strategies targeted at high-risk groups, Streptococcus pneumoniae (the pneumococcus) remains the most common cause of CAP. …”
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The Disappearance of COVID-19 Data Dashboards: The Case of Ephemeral Data by Melinda Laituri, Yogya Kalra, Chaowei Yang

“…Data dashboards tracked global and country-specific statistics and provided cartographic visualizations of cases, deaths, vaccination rates and other metrics. We examined the role of geospatial data on COVID-19 dashboards in the form of maps, charts, and graphs. …”
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The Societal Impact of Herpes Zoster and Postherpetic Neuralgia on Patients, Life Partners, and Children of Patients in Germany by Thomas Weinke, Andrea Glogger, Isabelle Bertrand, Kati Lukas

“…We need to raise the awareness of the general public about the real life impact of HZ and PHN and their often severe, debilitating consequences and the potential benefits from vaccination.…”
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Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysisResearch in context by Anis Rassi, Jr, Alyssa Grimshaw, Ashwin Sarwal, Ranjit Sah, Sangam Shah, Nelson I. Agudelo Higuita, Fabio Mahamed Rassi, Michaele Francesco Corbisiero, Hannah M. Kyllo, Jordan Stellern, Samantha Kaplan, Luis A. Marcos, Edgar A. Ramírez-García, Martin Casapia, Peter Hotez, Maria Elena Bottazzi, Shital Patel, Carlos Franco-Paredes, José Antonio Marin-Neto, Andrés F. Henao-Martínez

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