Production of a new variant of soluble trimer Env of HIV-1 CRF63_02A6 SOSIP.664 by Nadezhda B. Rudometova, Andrey P. Rudometov, Anastasia A. Fando, Danil I. Vahitov, Alexander A. Ilyichev, Alexander P. Agafonov, Larisa I. Karpenko

“…The obtained results indicate the prospects for further study of the structural features of the trimer Env CRF63_02A6 SOSIP.664, as well as its immunogenicity and the possibility of using it as a vaccine antigen.…”
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Atomic Force Microscopy (AFM) nanomechanical characterization of micro- and nanoplastics to support environmental investigations in groundwater by Massimiliano Galluzzi, Michele Lancia, Chunmiao Zheng, Viviana Re, Valter Castelvetro, Shifeng Guo, Stefano Viaroli

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Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening by Hengrui Liu, Arie Zask, Farhad Forouhar, Sho Iketani, Alana Williams, Daniel R. Vaz, Dahlya Habashi, Karenna Choi, Samuel J. Resnick, Seo Jung Hong, David H. Lovett, Tian Bai, Alejandro Chavez, David D. Ho, Brent R. Stockwell

“…Due to the limited efficacy of vaccines against SARS-CoV-2 and resistance to current therapies, additional anti-viral therapeutics with pan-coronavirus activity are of high interest. …”
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Genotyping <em> Escherichia coli </em> O157:H7 strains isolated from cattle and small ruminants in Fars province (Iran) using Enterobacterial Repetitive Intergenic Consensus PCR A... by Sedigheh Mokhtari, Yahya Tahamtan, Mohammad Kargar, Keyvan Tadayon, Elham Moazamian

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The Prevalence of High Carcinogenic Risk of HPV Genotypes among HIV-Positive and HIV-Negative MSM from Russia by Ilia Beliakov, Maria Senina, Yuriy Tyulenev, Elena Novoselova, Viktor Surovtsev, Alexander Guschin

“…According to our data, 25% of HIV-positive MSM have HPV39; this is the only one of the five types of HR HPV (16, 18, 58, 33, and 39) associated with this group of MSM that has not yet been included in the HPV vaccines available on the market.…”
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Multi-platform diagnostic strategy and biosecurity as basis of contagious agalactia control programs in endemic areas by Christian De la Fe, Ana Grau, Olga Minguez, Antonio Sánchez, Rosario Esquivel, Juan C. Corrales

“…Vaccination against AC proved to be a protective factor against the occurrence of herds with bucks or rams testing positive. …”
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The incidence of radiologically verified community-acquired pneumonia requiring hospitalisation in adults living in southern Sweden, 2016-2018: a population-based study by Elisabeth Rünow, Frida Valeur, Gustav Torisson, Karin Hansen, Christian Theilacker, Kristian Riesbeck, Jonas Ahl

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Characterising COVID-19 empirical research production in Latin America and the Caribbean: A scoping review. by Cristián Mansilla, Cristian A Herrera, Laura Boeira, Andrea Yearwood, Analia S Lopez, Luis E Colunga-Lozano, Eva Brocard, Tatiana Villacres, Marcela Vélez, Gabriel Di Paolantonio, Ludovic Reveiz

“…<h4>Conclusion</h4>During the first part of the COVID-19 pandemic, LAC countries have contributed to the global research effort primarily with epidemiological studies, with little participation on vaccines research, meaning that this type of knowledge would be imported from elsewhere. …”
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Interactions between Leishmania braziliensis and Macrophages Are Dependent on the Cytoskeleton and Myosin Va by Elisama Azevedo, Leandro Teixeira Oliveira, Ana Karina Castro Lima, Rodrigo Terra, Patrícia Maria Lourenço Dutra, Verônica P. Salerno

“…Leishmaniasis is a neglected tropical disease with no effective vaccines. Actin, microtubules and the actin-based molecular motor myosin Va were investigated for their involvement in Leishmania braziliensis macrophage interactions. …”
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Social network analysis of key stakeholders in Brucellosis prevention in Western Iran by Meysam Behzadifar, Mohammad Yarahmadi, Ahad Bakhtiari, Sahar Kargar, Saeed Shahabi, Samad Azari, Mariano Martini, Masoud Behzadifar

“…Economic constraints, such as the high cost of vaccines, along with limited public awareness, further hinder effective control efforts. …”
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

“…African trypanosomiasis is a major neglected tropical disease with significant health and economic concerns in sub-Saharan Africa. In the absence of vaccines for African trypanosomiasis, there is a consideration for alternative sources of chemotherapy. …”
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Decreasing hepatitis B seroprevalence in pregnant women in Taiwan between 2016 and 2021: a claim-based cohort study by Li-Nien Chien, Juan C. Vargas-Zambrano, Meng-Yun Ku

“…Abstract Background Hepatitis B virus (HBV) surface antigen (HBsAg) seroprevalence was high before the national vaccine policy was introduced in Taiwan, indicating significant HBV infection rates. …”
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Generation of Chicken IgY against SARS-COV-2 Spike Protein and Epitope Mapping by Yan Lu, Yajun Wang, Zhen Zhang, Jingliang Huang, Meicun Yao, Guobin Huang, Yuanyuan Ge, Peichun Zhang, Huaxin Huang, Yong Wang, Huiliang Li, Wen Wang

“…Repurposing approved drugs, developing vaccines and employing passive immunization are three major therapeutic approaches to fighting COVID-19. …”
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Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment by A. G. Galeeva, A. R. Akhunova, K. V. Usoltsev, N. I. Khammadov, M. A. Efimova

“…Optimal PCVD prevention is known to be achieved through a set of veterinary and sanitary measures in combination with vaccination. High evolutionary virus variability facilitating new genotype and strain emergence requires development of new candidate recombinant vaccines against PCV-2 infection. …”
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COVID-19–sensitive tumour response: 2-year assessment of the SARS-CoV-2 humoral response in cancer patients in oncology hospital in Poland by Piotr Kosiorek, Bożena Mikołuć, Samuel Stróż, Anna Hryniewicz, Dorota E. Kazberuk, Robert Milewski, Anna Grzeszczuk, Magdalena J. Borkowska, Anna Stasiak‐Barmuta

“…Abstract Vaccination has been considered the most crucial defence against viral infections, including SARS-CoV-2. …”
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Heterogeneity of avian infectious bronchitis virus population by Ye. V. Ovchinnikova, L. O. Scherbakova, S. N. Kolosov, A. N. Andriyasova, N. G. Zinyakov, Z. B. Nikonova, A. A. Kozlov, P. B. Akshalova, D. A. Altunin, D. B. Andreychuk

“…This is facilitated by widespread use of live vaccines, simultaneous circulation of field viruses belonging to different serotypes in one flock and rapid spread of the virus. …”
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The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains by Joseph N. Patria, Luka Jwander, Ifeoma Mbachu, Levi Parcells, Brian Ladman, Jakob Trimpert, Benedikt B. Kaufer, Phaedra Tavlarides-Hontz, Mark S. Parcells

“…Over the last 50 years, losses due to MDV infection have been controlled worldwide through vaccination; however, these live-attenuated vaccines are non-sterilizing and potentially contributed to the virulence evolution of MDV field strains. …”
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In Silico Screening of Putative Corynebacterium pseudotuberculosis Antigens and Serological Diagnosis for Caseous Lymphadenitis in Sheep by Enzyme-Linked Immunosorbent Assay by Daniela Droppa-Almeida, Caroline de Santana Ferreira, Ioná Brito, Sibele Borsuk, Jorge Alberto López Rodríguez, Isabel Bezerra Lima-Verde, Francine Ferreira Padilha

“…In this context, several strategies in an attempt to discover new antigens to compose diagnosis assays or vaccines are fundamental. Therefore, this study aimed to use bioinformatics software to evaluate the critical chemical characteristics of unknown proteins of C. pseudotuberculosis by selecting them for heterologous expression in Escherichia coli. …”
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Peripheral lncRNA NEAT-1, miR374b-5p, and IL6 panel to guide in COVID-19 patients' diagnosis and prognosis. by Marwa A Ali, Olfat G Shaker, Eman M Ezzat, El Shaimaa Gomaa Ali, Mahmoud I Aboelor, Mona I Ahmed, Essam A Hassan, Doaa Y Ali, Heba Mostafa Ahmed, Abeer A Khalefa, Rasha A Hussein, Ahmed Fathy Elkhateeb, Esam Ali Mohamed

“…<h4>Background</h4>The SARS-CoV-2 virus's frequent mutations have made disease control with vaccines and antiviral drugs difficult; as a result, there is a need for more effective coronavirus drugs. …”
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Exploring phytochemical, antioxidant, and antimicrobial properties of Plumeria pudica Jacq. leaves by Kavan Shukla, Kunal N. Odedra, B. A. Jadeja

“…Abstract Since the emergence of the coronavirus disease, there has been a notable surge in demand for herbal remedies with minimal or no adverse effects. Notably, existing vaccines and medications employed in its treatment have exhibited significant side effects, some of which have proven fatal. …”
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