A machine learning and clustering-based approach for county-level COVID-19 analysis. by Charles Nicholson, Lex Beattie, Matthew Beattie, Talayeh Razzaghi, Sixia Chen

“…This paper employs both supervised and unsupervised methods to identify the critical county-level demographic, mobility, weather, medical capacity, and health related county-level factors for studying COVID-19 propagation prior to the widespread availability of a vaccine. We use this feature subspace to aggregate counties into meaningful clusters to support more refined disease analysis efforts.…”
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Pertussis Reinfection in an Adult: A Cause of Persistent Cough Not to Be Ignored by Theocharis Koufakis, Anastasia Paschala, Dimitrios Siapardanis

“…Despite the fact that reinfection after natural disease or vaccination is not uncommon, the index of clinical suspicion of pertussis diagnosis in adults remains low. …”
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Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205 by Luciana D’Apice, Valerio Costa, Rossella Sartorius, Maria Trovato, Marianna Aprile, Piergiuseppe De Berardinis

“…The filamentous bacteriophage fd, codisplaying antigenic determinants and a single chain antibody fragment directed against the dendritic cell receptor DEC-205, is a promising vaccine candidate for its safety and its ability to elicit innate and adaptive immune response in absence of adjuvants. …”
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Novel coronavirus 2019-nCoV: Could this virus become a possible global pandemic by Vengadesh Letchumanan, Nurul-Syakima Ab Mutalib, Bey-Hing Goh, Learn-Han Lee

“…At this point, there is no specific drug or vaccine to treat infected patients besides supportive care. …”
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HIV and Malnutrition: Effects on Immune System by Shalini Duggal, Tulsi Das Chugh, Ashish Kumar Duggal

“…Continuous research is being done in many parts of the world regarding its treatment and vaccine development, and a lot of money has flown into this. …”
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Development and Validation of Chlamydia muridarum Mouse Models for Studying Genital Tract Infection Pathogenesis by Yihui Wang, Zixuan Han, Luying Wang, Xin Sun, Qi Tian, Tianyuan Zhang

“…Animal infection models play significant roles in the study of bacterial pathogenic mechanisms and host–pathogen interactions, as well as in evaluating drug and vaccine efficacies. Chlamydia trachomatis is responsible for infections in various mucosal tissues, including the eyes and urogenital, respiratory, and gastrointestinal tracts. …”
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Trafficked Proteins—Druggable in Plasmodium falciparum? by Jasmin Lindner, Kamila Anna Meissner, Isolmar Schettert, Carsten Wrenger

“…Annually this parasitic disease leads to more than half a million deaths; most of these are children in Africa. An effective vaccine is not available, and the treatment of the disease is solely dependent on chemotherapy. …”
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Tetanus Complicated by Dysautonomia: A Case Report and Review of Management by Nishant Sharma, Si Li, Metlapalli Venkata Sravanthi, Dan Kazmierski, Yichen Wang, Amit Sharma, Pragya Dhaubhadel

“…Tetanus is a life-threatening infectious neurological disorder that is now a rare disease due to the institution of wide-spread vaccination strategies. We present an uncommon case of generalized severe tetanus with consequent respiratory failure requiring mechanical ventilation, which was associated with dysautonomia. …”
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[IN1438] Dengue and Dengue Virus in Florida by Yasmin V. Ortiz, Daniel W. Pérez-Ramos, Eric P. Caragata, Panpim Thongsripong

“…The biology and ecology of the primary vectors, Aedes aegypti and Aedes albopictus, play  important roles in the disease's transmission cycle. No vaccine and no specific antiviral treatments are yet available, and diagnosis is difficult because dengue symptoms overlap with those of other, similar febrile illnesses. …”
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COVID-19 Situation in Thailand by Yi-He Kuai, Hooi-Leng Ser

“…The health authorities in Thailand are constantly promoting the COVID-19 vaccination plan to achieve herd immunity against the coronavirus. …”
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Helicobacter pylori: Basic Mechanisms to Clinical Cure by ABR Thomson, CN Williams

“…Therapy of H pylori infection is complicated and involves dual therapy with an antibiotic plus a protein pump inhibitor, such as omeprazole 20 mg bid plus amoxicillin 1 g bid for two weeks, triple or quadruple therapy with bismuth, two antibiotics and an H2-receptor antagonist. Vaccination against H pylori is on the far horizon.…”
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Mange in Rabbits: An Ectoparasitic Disease with a Zoonotic Potential by Wafaa A. Abd El-Ghany

“…Control measures mainly depend on the use of different types of systemic and topical acaricides and the use of natural products and supportive elements. Vaccine is not commercially available and is still under investigation. …”
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Anti-phenolic glycolipid antibodies in Mycobacterium bovis infected cattle by Zijie Zhou, Anouk van Hooij, J. Hessel M. van Dijk, Nina Musch, Louise Pierneef, Hamza Khalid, Kees Franken, Thomas Holder, Neil Watt, Anita L. Michel, Jeroen D.C. Codée, Martin Vordermeier, Paul L.A.M. Corstjens, Elisabeth M.D.L. van der Heijden, Jayne C. Hope, Annemieke Geluk

“…The sensitivity for anti-M. bovis PGL IgM in infected animals was, however, moderate (44.9 %) and the false-positive rate was 6.3 % in SICCT-negative cattle. Notably, vaccination with BCG- or heat-killed M. bovis did not affect serum levels of anti-M. bovis PGL IgM in cattle. …”
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On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance, health and robustness in broiler chickens by Guilloteau, Laurence A, Bertin, Aline, Crochet, Sabine, Bagnard, Charlotte, Hondelatte, Alice, Ravon, Laure, Schouler, Catherine, Germain, Karine, Collin, Anne

“…On their return to the original room, the chicken density was increased, and birds were orally vaccinated with the Gumboro vaccine. The impacts of these conditions on hatchability, chick quality score, performance, health and robustness were determined. …”
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Short-term effects of air pollution on the infectious disease spectrum in Shanghai, China: a time-series analysis from 2013 to 2019 by Yihan Lin, Hao Meng, Yong He, Wenzhuo Liang, Yiran Niu, Zhenliang Liu, Ziying Wang, Yangyang Tian, Shiyang Chang

“…A 10 μg/m3 increase in O3 was associated with a higher risk of total NNIDs (relative risk [RR] at lag 1 month: 1.29, 95% confidence interval [CI]: 1.02–1.65), vaccine-preventable diseases (RR at lag 1 month: 1.75, 95% CI: 1.02–3.01), and sexually transmitted and bloodborne diseases (RR at lag 2 month: 1.12, 95% CI: 1.00–1.26). …”
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Characterisation of EfbA from the Endodontic Pathogen Enterococcus faecalis and Prediction of Immunodominant EfbA Epitope Peptides: An In-vitro and In-silico Study by Dev Arora, AS Smiline Girija, J Vijayashree Priyadharsini

“…Thus, there is a need to identify novel vaccine candidates as immunodominant epitope peptides from the Enterococcal Fibronectin Binding Protein-A (EfbA) protein for E. faecalis. …”
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A bioinformatics approach for identifying the probable cause of the cross-interaction of antibodies to the antigenic protein HPV16 L1 with the HPV6 L1 protein by A. S. Stolbikov, R. K. Salyaev, N. I. Rekoslavskaya

“…In this work, the amino acid sequences of HPV16 L1 and HPV6 L1 used for the development of a binary vaccine against cervical cancer and anogenital papillomatosis have been analyzed. …”
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Who is engaging with lateral flow testing for COVID-19 in the UK? The COVID-19 Rapid Survey of Adherence to Interventions and Responses (CORSAIR) study by Nicola T Fear, Susan Michie, Richard Amlot, G James Rubin, Louise E Smith, Henry WW Potts

“…Increased uptake of testing was associated with being vaccinated (adjusted ORs (aORs)=1.52–2.45, 95% CI 1.25 to 3.07, analysed separately by vaccine dose), employed (aOR=1.94, 95% CI 1.63 to 2.32), having been out to work in the last week (aOR=2.30, 95% CI 1.94 to 2.73) and working in a sector that adopted LFT early (aOR=2.54, 95% CI 2.14 to 3.02) . …”
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Du macaque rhésus au macaque fascicularis : le refus de l’Inde de l’exportation de ses rhésus (1970-1990) by Laure Hoenen

“…The use of the rhesus monkey as an animal model in biomedical research during the 1950’s, principally for toxicity tests and polio vaccine production, fostered a dependence upon countries that exported these animals. …”
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Recent Advances in Peptide-Loaded PLGA Nanocarriers for Drug Delivery and Regenerative Medicine by Hossein Omidian, Renae L. Wilson, Ana M. Castejon

“…The versatility of PLGA nanocarriers extends across therapeutic domains, including cancer therapy, neurodegenerative diseases, vaccine development, and regenerative medicine. Innovations in polymer chemistry, surface functionalization, and advanced manufacturing techniques, such as microfluidics and electrospraying, have further enhanced the efficacy and scalability of these systems. …”
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