Estimation of respiratory syncytial virus-associated hospital admissions in five European countries: a modelling studyResearch in context by Caroline Klint Johannesen, David Gideonse, Richard Osei-Yeboah, Toni Lehtonen, Ombeline Jollivet, Rachel A. Cohen, Arantxa Urchueguía-Fornes, María Herrero-Silvestre, Mónica López-Lacort, Rolf Kramer, Thea K. Fischer, Terho Heikkinen, Harish Nair, Harry Campbell, Michiel van Boven, Harish Nair, Hanna Nohynek, Anne Teirlinck, Louis Bont, Peter Openshaw, Andrew Pollard, Veena Kumar, Elizabeth Begier, Jim Janimak, Jenny Hendrix, Rolf Kramer, Alejandro Orrico Sánchez, Eva Molero

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Specifically blocking αvβ8-mediated TGF-β signaling to reverse immunosuppression by modulating macrophage polarization by Cuicui Guo, Hui Sun, Yulei Du, Xiaodong Dai, Yu Pang, Zhen Han, Xinhui Xiong, Shaowei Li, Junhua Zhang, Qingbing Zheng, Xun Gui

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Increased serum soluble PD-l1 levels in patients with advanced stages of chronic kidney disease by Ayaka Hayashi, Ayaka Hayashi, Hiroto Ishihara, Mayuko Kawabe, Kazuhiko Kato, Kazuhiko Kato, Akio Nakashima, Akio Nakashima, Izumi Yamamoto, Teppei Sakano, Teppei Sakano, Hiroe Kobashi, Makoto Morita, Makoto Morita, Takashi Yokoo, Mitsuyoshi Urashima

“…In the Vaccine and Cancer cohorts, sPD-L1 levels increased significantly with age (P < 0.001) and male sex (P < 0.001). …”
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Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms by Billy Ogwel, Vincent H. Mzazi, Alex O. Awuor, Caleb Okonji, Raphael O. Anyango, Caren Oreso, John B. Ochieng, Stephen Munga, Dilruba Nasrin, Kirkby D. Tickell, Patricia B. Pavlinac, Karen L. Kotloff, Richard Omore

“…We used 7 ML algorithms to build prognostic models for the prediction of LDD among children < 5 years using de-identified data from Vaccine Impact on Diarrhea in Africa study (N = 1,482) in model development and data from Enterics for Global Health Shigella study (N = 682) in temporal validation of the champion model. …”
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Clinical, pathological, and genotypic analysis of infectious bronchitis virus in broiler chickens in the Abu Dhabi Emirate, United Arab Emirates by Hassan Zackaria Ali Ishag, Abdelnasir Mohammed Adam Terab, Ebrahim Mohamad Abdalsalam Osman, El Tigani Ahmed El Tigani-Asil, El Tigani Ahmed El Tigani-Asil, Mohammed Saleh Albreiki, Oum Keltoum Bensalah, Asma Abdi Mohamed Shah, Abdelmalik Ibrahim Khalafalla

“…This complex scenario of different IBV lineages circulation may account for the persistent outbreaks despite vaccination efforts. The results of the study are crucial for optimum IB vaccination and monitoring strategies or designing new vaccines based on local IBV field strains.…”
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Inflammation and Infection in Critical Care Medicine by Jesús F. Bermejo-Martin, Ignacio Martín-Loeches, Steven Bosinger

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Inflammatory Mediators in Autoimmunity and Systemic Autoimmune Diseases by Britt Nakken, György Nagy, Peter C. Huszthy, Even Fossum, Yrjö Konttinen, Peter Szodoray

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Rabies Elimination: Is It Feasible without Considering Wildlife? by Krishna Prasad Acharya, Rakesh Chand, Falk Huettmann, Tirth Raj Ghimire

“…Rabies is a vaccine-preventable fatal viral disease that is zoonotic in nature. …”
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Influenza Immunization Practices and Policies for Health Care Students in Canada by Kiersten Pianosi, Tara Chobotuk, Beth A Halperin, Scott A Halperin

“…Little is known about how health care student programs provide information about influenza vaccination to their students, deliver vaccines and document their vaccination status.…”
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Immunity to Visceral Leishmaniasis by Nahid Ali, Asrat Hailu Mekuria, Jose M. Requena, Christian Engwerda

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Optimization of Conditions for Expression of Dengue Serotype 2 EDIII Protein in <i>Escherichia coli</i> and Immune Responses of Adjuvant-Free EDIII Ferritin Nanoparticles Against D... by M.S.B.W.T.M. Nipuna Sudaraka Tennakoon, Kyoung-Ho Lee, Hye-Mi Lee, Jae-Yeon Park, Hyun-Jin Shin

“…Self-assembling ferritin nanoparticle technology is a widely used vaccine development platform for enhancing the efficacy of subunit vaccines by displaying multiple antigens on nanocages. …”
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Seroprevalence of SARS-CoV-2 and risk factors for infection among children in Uganda: A serial cross-sectional study. by Irene Bagala, Jane Frances Namuganga, Patience Nayebare, Gloria Cuu, Thomas Katairo, Isaiah Nabende, Samuel Gonahasa, Martha Nassali, Stephen Tukwasibwe, Grant Dorsey, Joaniter I Nankabirwa, Sabrina Bakeera-Kitaka, Sarah Kiguli, Bryan Greenhouse, Isaac Ssewanyana, Moses R Kamya, Jessica Briggs

“…By the follow-up survey, 52.7% of adults had received at least one COVID-19 vaccine dose. Overall seroprevalence in children was higher at follow-up compared to baseline (71.6% versus 19.2%, p < 0.001). …”
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Outer Membrane Proteome Analysis of Indian Strain of Pasteurella multocida Serotype B:2 by MALDI-TOF/MS Analysis by A. Prasannavadhana, Santosh Kumar, Prasad Thomas, Laxmi Narayan Sarangi, Santosh Kumar Gupta, Adyasha Priyadarshini, Viswas Konasagara Nagaleekar, Vijendra Pal Singh

“…Further functional in vivo study of the proteins identified are required to explore the utility of these proteins in developing diagnostics and vaccine against HS.…”
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Subnational trends and inequalities of under-immunisation and zero-dose among children aged 12–23 months in Uganda: a national population-based cross-sectional study by Aluísio J D Barros, Peter Waiswa, Rornald Muhumuza Kananura, Jennifer Harris Requejo, Ronald Wasswa, Thiago M Santos

“…Objective Despite the Global Vaccine Action Plan’s goal of at least 90% vaccine coverage for all children, Uganda has made limited progress in vaccination over the past decade. …”
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Cross-Cultural Sense-Making of Global Health Crises: A Text Mining Study of Public Opinions on Social Media Related to the COVID-19 Pandemic in Developed and Developing Economies by Adham Kahlawi, Firas Masri, Wasim Ahmed, Josep Vidal-Alaball

“…Over time, all 3 countries displayed a shift in discourse toward vaccine-related topics during the later phase of the pandemic, highlighting its global significance. …”
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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

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Immunizing adult female mice with a TcpA-A2-CTB chimera provides a high level of protection for their pups in the infant mouse model of cholera. by Gregory A Price, Randall K Holmes

“…These data support the concept of including both TcpA and CTB as immunogens in development of an effective multivalent subunit vaccine against V. cholerae.…”
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Phage display as a tool for identifying HIV-1 broadly neutralizing antibodies by A. N. Chikaev, A. P. Rudometov, Yu. A. Merkulyeva, L. I. Karpenko

“…A major obstacle to the development of an effective HIV vaccine is an extensive genetic and antigenic variability of the virus. …”
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Detection and Phylogenetic Analysis of an Exotic Strain of Porcine Epidemic Diarrhea Virus and Its Effect on an Affected Herd Immunized Against the Endemic Strain in Thailand by Christopher James Stott, Patumporn Jermsutjarit, Pornchai Pornpanom, Hongyao Lin, Angkana Tantituvanont, Dachrit Nilubol

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Evaluation of Melongosides as Potential Inhibitors of NS2B-NS3 Activator-Protease of Dengue Virus (Serotype 2) by Using Molecular Docking and Dynamics Simulation Approach by Partha Biswas, Ommay Hany Rumi, Dhrubo Ahmed Khan, Md Nasir Ahmed, Nusratun Nahar, Rownak Jahan, Md Nazmul Hasan Zilani, Tridib K Paul, Anamul Hasan, Tohmina Afroze Bondhon, Khoshnur Jannat, Md Nazmul Hasan, Mohammed Rahmatullah

“…Dengue has no available drugs for treatment; CYD-TDV is the only vaccine thus far approved for use by a few countries in the world. …”
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