Protein-Protein Interactions Inferred from Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences by Chuan-Ching Huang, Chuan Yi Tang

“…However, no efficient vaccine for NoVs exists because of their variable genome sequences. …”
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[IN1438] Dengue and Dengue Virus in Florida by Yasmin V. Ortiz, Daniel W. Pérez-Ramos, Eric P. Caragata, Panpim Thongsripong

“…The biology and ecology of the primary vectors, Aedes aegypti and Aedes albopictus, play  important roles in the disease's transmission cycle. No vaccine and no specific antiviral treatments are yet available, and diagnosis is difficult because dengue symptoms overlap with those of other, similar febrile illnesses. …”
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VALIDATION OF REAL-TIME REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION FOR INDIRECT ASSESSMENT OF FMD VIRUS TITRE by D. A. Lozovoy, M. I. Doronin, V. A. Starikov, D. V. Mikhalishin, A. A. Shishkova, A. M. Timina, A. B. Borisov

“…Procedure for validation of the method for indirect assessment of cultural FMD virus titre (T FMDV) in raw materials used for vaccine production with real time reverse transcription polymerase chain reaction (RT-PCRrt) based on determined amplifcation threshold cycle value (Ct) using linear regression model, TFMDV= –0.2956Ct+ 11.4650, is described in the paper. …”
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Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysisResearch in context by Anis Rassi, Jr, Alyssa Grimshaw, Ashwin Sarwal, Ranjit Sah, Sangam Shah, Nelson I. Agudelo Higuita, Fabio Mahamed Rassi, Michaele Francesco Corbisiero, Hannah M. Kyllo, Jordan Stellern, Samantha Kaplan, Luis A. Marcos, Edgar A. Ramírez-García, Martin Casapia, Peter Hotez, Maria Elena Bottazzi, Shital Patel, Carlos Franco-Paredes, José Antonio Marin-Neto, Andrés F. Henao-Martínez

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Nonviral targeted mRNA delivery: principles, progresses, and challenges by Xi He, Guohong Li, Letao Huang, Haixing Shi, Sha Zhong, Siyu Zhao, Xiangyu Jiao, Jinxiu Xin, Xiaoling Yin, Shengbin Liu, Zhongshan He, Mengran Guo, Chunli Yang, Zhaohui Jin, Jun Guo, Xiangrong Song

“…Abstract Messenger RNA (mRNA) therapeutics have garnered considerable attention due to their remarkable efficacy in the treatment of various diseases. The COVID‐19 mRNA vaccine and RSV mRNA vaccine have been approved on the market. …”
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Pandemic Fictions: Covid-19 and the Cultures of Dystopia by Sean Mark

“…Dystopian works like 1984, The Eyes of Darkness, The Matrix and Black Mirror have been lauded for their foresight, while former health secretary, Matt Hancock, has stated that watching Contagion affected his planning of the vaccine rollout. This essay reflects on the relationship between dystopian cultures and Covid-19, examining, firstly, the role that figurations of dystopia have played in the collective and political response to the pandemic. …”
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Algorithms for Processing Coronavirus Genomes for the Goals and Objectives of Modern Immunoinformatics, Vaccinomics, and Virology by M. V. Sprindzuk, A. S. Vladyko, L. P. Titov, Lu Zhuozhuang, V. I. Bernik

“…However, for the complete analysis and implementation of, for example, the epitope vaccines, subsequent validation by the laboratory and in vivo experiments are required.…”
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Aging Adults and Seasonal Influenza: Does the Vitamin D Status (H)Arm the Body? by Pierre Olivier Lang, Dimitrios Samaras

“…Evidence that VitD affects clearance of selected pathogens is supported by epidemiological and clinical data, while its coadministration with influenza vaccine in mice enhanced both mucosal and systemic antibody responses. …”
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Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections by Aziz Alami Chentoufi, Lbachir BenMohamed

“…The progress and limitations in developing a safe and efficient mucosal herpes vaccine are discussed.…”
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Epitope mapping of recombinant Salmonella enterica serotype Heidelberg flagellar hook-associated protein by in silico and in vivo approaches by Hung-Yueh Yeh

“…Conclusions These findings provide a rational for further evaluation of these shared linear epitopes in vaccine development to cover the chicken population.…”
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Compartmental Models Driven by Renewal Processes: Survival Analysis and Applications to SVIS Epidemic Models by Divine Wanduku, Md Mahmud Hasan

“…Applications are provided for the SVIS (Susceptible-Vaccinated-Infected-Susceptible) disease epidemic model to investigate the impacts of hazard rate functions (HRFs) on disease control. …”
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AFRICAN SWINE FEVER VIRUS: USE OF GENETIC MARKERS IN ANALYSIS OF ITS ROUTES OF SPREAD by A. Mazloum, A. S. Igolkin, N. N. Vlasova, D. V. Romenskaya

“…Specific structure of the virus and long genome, encoding genes with unknown function, and circulation of 24 genotypes and 9 serotypes of the virus hinder the development of ASF vaccine. The article shows that the use of many specific genetic markers during determination of relationship and study of pathways of ASF virus global spread is the most accurate method.…”
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Imaging Early Steps of Sindbis Virus Infection by Total Internal Reflection Fluorescence Microscopy by Youling Gu, Yuanzheng Yang, Yuechueng Liu

“…Sindbis virus (SINV) is an alphavirus that has a broad host range and has been widely used as a vector for recombinant gene transduction, DNA-based vaccine production, and oncolytic cancer therapy. …”
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Significance of Persistent Inflammation in Respiratory Disorders Induced by Nanoparticles by Yasuo Morimoto, Hiroto Izumi, Etsushi Kuroda

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Drug Target Identification and Prioritization for Treatment of Ovine Foot Rot: An In Silico Approach by Abhishek Acharya, Lalit C. Garg

“…These proteins may be considered as potential vaccine candidates or drug targets for designing antibiotics against the bacterium. …”
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Long-Term Survival and PSA Control with Radiation and Immunotherapy for Node Positive Prostate Cancer by M. Kamrava, Kwong Y. Tsang, R. A. Madan, A. Kaushal, C. N. Coleman, J. Gulley

“…Further evaluation of therapeutic cancer vaccines in combination with radiation and hormonal therapy in the definitive management of prostate cancer is warranted.…”
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Laboratory Diagnosis of Mumps in a Partially Immunized Population: The Nova Scotia Experience by TF Hatchette, R Davidson, S Clay, J Pettipas, J LeBlanc, S Sarwal, M Smieja, KR Forward

“…BACKGROUND: In 2007, Atlantic Canada experienced a large outbreak of mumps predominately in university students who had received a single dose of measles, mumps and rubella vaccine. The present study describes the performance characteristics of reverse transcriptase polymerase chain reaction (RT-PCR) on buccal and urine specimens and immunoglobulin M (IgM) serology in this partially immune population.…”
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Maternal Satisfaction towards Childhood Immunization Service and Its Associated Factors in Wadla District, North Wollo, Ethiopia, 2019 by Fisha Alebel GebreEyesus, Nega Tezera Assimamaw, Netsanet Tsegaye GebereEgziabher, Bisrat Zeleke Shiferaw

“…Furthermore, the multivariable logistic regression analysis showed that short waiting time before receiving service [AOR=1.83; 95%CI=1.21−2.79], greeting from care providers, [AOR=5.69; 95%CI=3.36−9.65], having information about the current vaccine [AOR=2.03; 95%CI=1.25−3.32], dose of vaccine [AOR=2.24; 95%CI=1.40−3.58], and next immunization schedule [AOR=3.21; 95%CI=1.70−6.04] were also significantly associated with maternal satisfaction towards childhood immunization services. …”
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Tracking acute flaccid paralysis in Niger: a half-decade epidemiological portrait (2016–2021) by El Khalef Ishagh, Marc Talatou Ouédraogo, Batouré Oumarou, Mutenda Sheria Kaya, Gbaguidi Aichatou Diawara, Abdoulaye Macire Camara, Seyni Moussa, Kuyangisa Bienvenu, Joseph Toko, Hamidou Harouna, Haladou Moussa, N.’Zue Kofi, Jacques L. Tamuzi, Patrick D. M. C. Katoto, Charles S. Wiysonge, Blanche-Philomene Melanga Anya, Manengu Casimir Tshikolasoni

“…Abstract Background Recently, a total of 74 circulating vaccine-derived poliovirus (cVDPV) outbreaks were detected in 39 countries, with 672 confirmed Acute Flaccid Paralysis (AFP) cases identified in 27 countries. …”
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Immunisation schedule of the Pediatric Spanish Association: 2024 recommendations by Francisco José Álvarez García, Antonio Iofrío de Arce, Javier Álvarez Aldeán, Elisa Garrote Llanos, Lucía López Granados, María Luisa Navarro Gómez, Valentín Pineda Solas, Irene Rivero Calle, Jesús Ruiz-Contreras, Ignacio Salamanca de la Cueva, Pepe Serrano Marchuet, Francisco José Álvarez García, Antonio Iofrío de Arce, Javier Álvarez Aldeán, María Garcés-Sánchez, Elisa Garrote Llanos, Abián Montesdeoca Melián, María Luisa Navarro Gómez, Valentín Pineda Solas, Irene Rivero Calle, Jesús Ruiz-Contreras, Pepe Serrano Marchuet

“…The AEP 2025 Vaccination and Immunization Schedule recommended for children, adolescents and pregnant women residing in Spain features the following novelties:Due to the increase in measles cases and outbreaks in recent years, we recommend advancing the second dose of measles, mumps and rubella (MMR) vaccine to 2 years of age.As a consequence of the above, since many autonomous communities (ACs) use the quadrivalent vaccine for the second dose of MMR and varicella vaccines, we recommend, for all ACs, advancing the second dose of varicella vaccine to 2 years of age.Due to the very significant increase in cases of pertussis since late 2023 and especially in 2024, we recommend advancing the dose of Tdap given in adolescence to 10–12 years of age.To complete protection against meningococcal disease in adolescence, we recommend vaccination against MenB at age 12 years.We believe that vaccination against seasonal influenza should be routine up to age 18 years, but given the disappointing coverage in children aged 6–59 months, we currently consider that improving this coverage should be prioritised, extending vaccination to children and adolescents aged 5–18 years once this objective has been achieved.Among other aspects, the routine immunization tables for healthy individuals and risk groups, the use of the new extended-valence conjugate vaccines against pneumococcal disease, routine vaccination at 4 months of age with MenACWY and vaccination against SARS-CoV-2 for individuals aged more than 6 months with risk factors remain unchanged with respect to the 2024 schedule. …”
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