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Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach
Published 2012-01-01“…Even with certain limitations, the technique has already shown significant promise to increase our understanding of parasite biology needed for rationalized drug and vaccine design. Further improvements to the mutagenesis technique and the design of novel genetic screens should lead us to some exciting discoveries about the critical weaknesses of Plasmodium, and greatly aid in the development of new disease intervention strategies.…”
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1522
The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains
Published 2024-12-01“…Over the last 50 years, losses due to MDV infection have been controlled worldwide through vaccination; however, these live-attenuated vaccines are non-sterilizing and potentially contributed to the virulence evolution of MDV field strains. …”
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1523
Characterisation of EfbA from the Endodontic Pathogen Enterococcus faecalis and Prediction of Immunodominant EfbA Epitope Peptides: An In-vitro and In-silico Study
Published 2025-01-01“…Thus, there is a need to identify novel vaccine candidates as immunodominant epitope peptides from the Enterococcal Fibronectin Binding Protein-A (EfbA) protein for E. faecalis. …”
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1524
A bioinformatics approach for identifying the probable cause of the cross-interaction of antibodies to the antigenic protein HPV16 L1 with the HPV6 L1 protein
Published 2021-12-01“…In this work, the amino acid sequences of HPV16 L1 and HPV6 L1 used for the development of a binary vaccine against cervical cancer and anogenital papillomatosis have been analyzed. …”
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Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade
Published 2025-01-01“…Abstract Previously, we demonstrated that natural host-defence peptide caerin 1.1/caerin 1.9 (F1/F3) increases the efficacy of anti-PD-1 and therapeutic vaccine, in a HPV16 + TC-1 tumour model, but the anti-tumor mechanism of F1/F3 is still unclear. …”
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1526
Assessing the resilience of child immunisation programmes using geospatial modelling and interrupted time series analysis in Ethiopia and Kenya amidst the COVID-19 pandemic: tracki...
Published 2024-07-01“…The resilience of child immunisation was due to the implementation of community-based healthcare, mobile vaccinations and collaboration and partnerships for mass vaccination campaigns. …”
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1527
The Mycoplasma hyopneumoniae protein Mhp274 elicits mucosal and systemic immune responses in mice
Published 2025-02-01“…The bottleneck in the development of more effective vaccines for MPS is the stimulation of effective immune responses in the host. …”
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1528
A machine learning and clustering-based approach for county-level COVID-19 analysis.
Published 2022-01-01“…This paper employs both supervised and unsupervised methods to identify the critical county-level demographic, mobility, weather, medical capacity, and health related county-level factors for studying COVID-19 propagation prior to the widespread availability of a vaccine. We use this feature subspace to aggregate counties into meaningful clusters to support more refined disease analysis efforts.…”
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1529
Du macaque rhésus au macaque fascicularis : le refus de l’Inde de l’exportation de ses rhésus (1970-1990)
Published 2018-03-01“…The use of the rhesus monkey as an animal model in biomedical research during the 1950’s, principally for toxicity tests and polio vaccine production, fostered a dependence upon countries that exported these animals. …”
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1530
Does the COVID-19 XBB Omicron subvariant signal the beginning of the end of the pandemic?
Published 2024-12-01“…This is to be expected in the natural evolution of a virus in a population highly vaccinated with a vaccine targeting the spike protein of the original Wuhan strain of the virus. …”
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1531
Clinical Features and Outcomes of Serotype 19A Invasive Pneumococcal Disease in Calgary, Alberta
Published 2014-01-01“…BACKGROUND: Streptoccocus pneumoniae serotype 19A (ST19A) became an important cause of invasive pneumococcal disease (IPD) after the introduction of the conjugate vaccine.…”
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1532
Hepatitis B virus infections in pregnant women and children in the era of HBV elimination
Published 2024-12-01“…Attention was paid to the incidence of latent HBV infections among children and adolescents and the role of the vaccine dose and additional hepatitis B booster vaccination in the prevention of HBV, especially in highly endemic areas and risk groups. …”
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1533
Fractional-Order Epidemic Model for Measles Infection
Published 2024-01-01“…Therefore, it is recommended that the government provide financial assistance for vaccine distribution.…”
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1534
2009 H1N1 Influenza
Published 2011-04-01“…We performed a literature search of PubMed using the following keywords: H1N1, influenza, vaccine, pregnancy, children, treatment, epidemiology, and review. …”
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Short-term effects of air pollution on the infectious disease spectrum in Shanghai, China: a time-series analysis from 2013 to 2019
Published 2025-01-01“…A 10 μg/m3 increase in O3 was associated with a higher risk of total NNIDs (relative risk [RR] at lag 1 month: 1.29, 95% confidence interval [CI]: 1.02–1.65), vaccine-preventable diseases (RR at lag 1 month: 1.75, 95% CI: 1.02–3.01), and sexually transmitted and bloodborne diseases (RR at lag 2 month: 1.12, 95% CI: 1.00–1.26). …”
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1538
Determinants maintaining healthcare personnel’s motivation during COVID-19 pandemic in Uganda
Published 2025-01-01“…COVID-19 knowledge was high, with over 70% answering questions correctly, although vaccine effectiveness had a slightly lower accuracy rate. …”
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1539
Assessment of Knowledge, Attitude and Practices of Health Workers Towards Hepatitis B Virus Infection Prevention in Health Centers of Bushenyi District.
Published 2024“…Thus, we recommend that all health workers in the health centers should be vaccinated before they enter into health professional practices.…”
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1540
Therapeutic Endoscopic Ultrasonography: Intratumoral Injection for Pancreatic Adenocarcinoma
Published 2013-01-01“…We then describe our technique in detail, including our experience injecting the AdV-tk adenoviral vector to create an in situ vaccine effect.…”
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