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    Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes by Liangliang Jiang, Tao Jiang, Jianhua Luo, Yanliang Kang, Yue Tong, Xiaoda Song, Xiangdong Gao, Wenbing Yao, Hong Tian

    Published 2019-01-01
    “…We obtained 30 fully human IgG antibody genes by sorting single B cells from the human immune system mice immunized with HER2-NitraTh vaccine. The analysis of antibody genes showed that sorted B cells underwent the extensive somatic mutation of the antibody genes. …”
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  4. 1424

    The Average IFN-γ Secreting Capacity of Specific CD8+ T Cells Is Compromised While Increasing Copies of a Single T Cell Epitope Encoded by DNA Vaccine by Yanmin Wan, Jing Wang, Haizhu Zhou, Zhidong Hu, Xiaonan Ren, Jianqing Xu

    Published 2012-01-01
    “…Previous studies suggested that both the frequency and the mean fluorescence intensity (MFI) of cytokine secreting T cells could be of great value for immunogenicity evaluation of a vaccine. In this study, by constructing epitope-based DNA vaccines encoding a previously identified CD8+ T cell epitope, we investigated the influence of multiplying epitope copies on both the frequency and the MFI of specific IFN-γ secreting CD8+ T cells. …”
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    High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents by Marloes I Hofstee, Joanna Kaczorowska, Abigail Postema, Erna Zomer, Maren van Waalwijk, Gustaaf Jonathans, Lia GH de Rond, Gaby Smits, Lotus L van den Hoogen, Gerco den Hartog, Anne-Marie Buisman

    Published 2025-01-01
    “…Methods In a two year longitudinal study with Dutch NH residents (n = 107), aged 50 years and over, we monitored antibody responses in serum prior to and after vaccination with a third, fourth BNT162b2 (wild-type; WT), and a BNT162b2 bivalent (WT/OMI BA.1) fifth vaccine. …”
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  8. 1428

    Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine by Sajib Chakraborty, Taibur Rahman, Rajib Chakravorty

    Published 2014-01-01
    “…Human immunodeficiency virus (HIV) possesses a major threat to the human life largely due to the unavailability of an efficacious vaccine and poor access to the antiretroviral drugs against this deadly virus. …”
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    COVID-19 vaccine uptake in Skåne county, Sweden, in relation to individual-level and area-level sociodemographic factors: a register-based cross-sectional analysis by Per-Olof Östergren, Louise Bennet, Jonas Björk, Adam Mitchell, Mahnaz Moghaddassi, Malin Inghammar

    Published 2024-04-01
    “…From these ORs, there were consistent differences in the estimated proportion vaccinated both for ≥2 doses and booster vaccination. …”
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