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Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes
Published 2019-01-01“…We obtained 30 fully human IgG antibody genes by sorting single B cells from the human immune system mice immunized with HER2-NitraTh vaccine. The analysis of antibody genes showed that sorted B cells underwent the extensive somatic mutation of the antibody genes. …”
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1424
The Average IFN-γ Secreting Capacity of Specific CD8+ T Cells Is Compromised While Increasing Copies of a Single T Cell Epitope Encoded by DNA Vaccine
Published 2012-01-01“…Previous studies suggested that both the frequency and the mean fluorescence intensity (MFI) of cytokine secreting T cells could be of great value for immunogenicity evaluation of a vaccine. In this study, by constructing epitope-based DNA vaccines encoding a previously identified CD8+ T cell epitope, we investigated the influence of multiplying epitope copies on both the frequency and the MFI of specific IFN-γ secreting CD8+ T cells. …”
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1426
Efficiency enhancement in main path extraction in mRNA vaccine field: A novel approach leveraging intermediate patents, with shielding origin and terminus patent edges
Published 2025-12-01Subjects: “…mRNA vaccine…”
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1427
High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents
Published 2025-01-01“…Methods In a two year longitudinal study with Dutch NH residents (n = 107), aged 50 years and over, we monitored antibody responses in serum prior to and after vaccination with a third, fourth BNT162b2 (wild-type; WT), and a BNT162b2 bivalent (WT/OMI BA.1) fifth vaccine. …”
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1428
Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine
Published 2014-01-01“…Human immunodeficiency virus (HIV) possesses a major threat to the human life largely due to the unavailability of an efficacious vaccine and poor access to the antiretroviral drugs against this deadly virus. …”
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1429
COVID-19 vaccine uptake in Skåne county, Sweden, in relation to individual-level and area-level sociodemographic factors: a register-based cross-sectional analysis
Published 2024-04-01“…From these ORs, there were consistent differences in the estimated proportion vaccinated both for ≥2 doses and booster vaccination. …”
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1430
The Expressions of the Immunity- and Muscle Development-Related Genes of 40-Day-Old Broilers Are Promoted in Response to the <i>In Ovo</i> and Dietary Supplemental Administration of Calcidiol in Conjunction with the <i>In Ovo</i> Administration of Marek’s Disease Vaccine
Published 2024-12-01Subjects: Get full text
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1431
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1432
Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis
Published 2025-01-01Subjects: Get full text
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1433
Tissue‐resident memory T cells in diseases and therapeutic strategies
Published 2025-01-01Subjects: Get full text
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1434
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1436
PfCSP-ferritin nanoparticle malaria vaccine antigen formulated with aluminum-salt and CpG 1018® adjuvants: Preformulation characterization, antigen-adjuvant interactions, and mouse immunogenicity studies
Published 2025-12-01Subjects: “…Malaria vaccine…”
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1437
Editorial: Antigen presentation in cancer immune responses
Published 2025-01-01Subjects: Get full text
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1438
Treatment approaches in advanced penile cancer: targeted therapies and immunotherapy
Published 2025-01-01Subjects: Get full text
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