Immunological efficiency of Haemophilus influenzae type b polyribosyl ribitol phosphate combined with detoxified lipooligosaccharide in a rabbit model by Amin Arsang, Seyed Davar Siadat, Masoumeh Saberpour, Farshad Nojoomi

“… Background and Objectives: Haemophilus influenzae type b (Hib) could cause severe life-threatening infections in children. Combine vaccines have reduced invasive diseases, but disease management is still necessary. …”
Get full text

EVALUATION OF POPULATION-LEVEL IMMUNITY TO SARS-COV-2 ACROSS BULGARIA (END OF 2023) by Kim Ngoc, Iva Trifonova, Teodora Gladnishka, Elitsa Panayotova, Evgenia Taseva, Vladislava Ivanova, Eleonora Kutevа, Iva Vladimirova, Iva Christova

“… Background: The COVID-19 pandemic in Bulgaria was characterized by a high mortality rate and vaccination efforts yielded suboptimal results. Understanding population immunity is important as new SARS-CoV-2 variants continue to emerge. …”
Get full text

Caecal Perforation from Primary Intestinal Tuberculosis in Pregnancy by Soe Lwin, Nina Lau Lee Jing, Haris Suharjono, Mardiana binti Kipli, Tin Moe Nwe, Myat San Yi, Lucas Luk Tien Wee

“…The incidence of tuberculosis (TB) is rising worldwide, despite the efficacy of the BCG vaccination. Populations at greatest risk of contracting TB are migrant communities, as well as immunocompromised individuals. …”
Get full text

A Case of Fulminant Meningococcemia: It Is All in the Complement by Kellie L. Hawkins, Mariah Hoffman, Sonia Okuyama, Sarah E. Rowan

“…As this new biologic agent becomes more widely prescribed, providers should be aware of the increased risk of meningococcemia. In addition to vaccination, providers may consider the use of oral penicillin for antibiotic prophylaxis against Neisseria meningitidis in these cases of functional complement deficiency.…”
Get full text

Different types of control over epidemic processes of pasteurellosis and haemorrhagic septicemia by S. I. Dzhupina

“…Correspondingly, the control over pasteurellosis epidemic process is realized by satisfaction of animal needs by environmental conditions (dry bedding, satisfactory air exchange, time in the open air, etc.) and the control over haemorrhagic cepticemia epidemic process is realized by vaccination of production animals according to epizooto-logical showings and use of repellents and insecticides.…”
Get full text

Modeling and analyzing the transmission dynamics of visceral leishmaniasis by Lan Zou, Jing Chen, Shigui Ruan

“…The basic reproduction number and sensitivity analysis show that the control of dog-sandfly transmission is more important for the elimination of the disease. Vaccination of susceptible dogs, treatment of infective dogs, as well as control of vertical transmission in dogs are effective prevention and control measures for visceral leishmaniasis.…”
Get full text

Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies. by Peter R McIlroy, Le Thanh Mai Pham, Thomas Sheffield, Maxwell A Stefan, Christine E Thatcher, James Jaryenneh, Jennifer L Schwedler, Anupama Sinha, Christopher A Sumner, Iris K A Jones, Stephen Won, Ryan C Bruneau, Dina R Weilhammer, Zhuoming Liu, Sean Whelan, Oscar A Negrete, Kenneth L Sale, Brooke Harmon

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to persist, demonstrating the risks posed by emerging infectious diseases to national security, public health, and the economy. Development of new vaccines and antibodies for emerging viral threats requires substantial resources and time, and traditional development platforms for vaccines and antibodies are often too slow to combat continuously evolving immunological escape variants, reducing their efficacy over time. …”
Get full text

Attitudes of Final-Year Medical Students in Jordan Towards Volunteering During a Pandemic by Alassaf A, Gharaibeh L, Alkubaisi F, Alkhawaldeh M, Dababseh S, Odeh R

“…Around 60% of students were willing to participate in future voluntary work that does not involve patients infected with COVID-19, while 29.3% of them were willing to do so depending on the type of pandemic and the availability of vaccines. There were 86.1% of students who thought that participating in voluntary work involving infected patients during pandemics, should be optional; where 10.1% suggested that it should be compulsory if vaccines were available.Conclusion: The majority of medical students did not volunteer during the COVID 19 pandemic. …”
Get full text

The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 by Lingxian Qiu, Wenting Luo, Youlan Chen, Zhinan Guo, Jiali Quan, Jiahuang Chi, Yingying Guan, Yue Huang, Yilan Lin

Get full text

One Health risk perception among the urban vulnerable dwellers of Gujarat, India: A cross-sectional assessment by Pratiksha Ganasva, Sandul Yasobant, Krupali Patel, Deepak Saxena

“…Another significant difference was observed in the perception on animal waste disposal sites with 58.9% of livestock keepers and 80.0% of non-livestock keepers considering such sites as risky factors (P=0.000). Furthermore, vaccination awareness was high, with 85.4% of livestock handlers and 88.7% of non-livestock handlers being aware of vaccination as a preventive measure against zoonotic diseases. …”
Get full text

Impact of non-pharmacological interventions on the first wave of COVID-19 in Portugal 2020 by Dinis B. Loyens, Constantino Caetano, Carlos Matias-Dias

“…Introduction: The COVID-19 pandemic caused over 7 million global deaths. Without vaccines during the first wave, governments implemented nonpharmacological interventions (NPIs) such as lockdowns, school closures, and travel restrictions. …”
Get full text

Anti-nucleocapsid SARS-CoV-2 antibody seroprevalence in previously infected persons with immunocompromising conditions-United States, 2020-2022. by Anna Bratcher, Jefferson M Jones, William A Meyer, Rehan Waheed, Huda Yazgi, Aaron Harris, Adi V Gundlapalli, Kristie E N Clarke

“…These individuals show weaker immunogenicity following vaccination than individuals without IC, yet immunogenicity after SARS-CoV-2 infection is poorly understood. …”
Get full text

Arginase-1-specific T cells target and modulate tumor-associated macrophages by Mads Hald Andersen, Inés Lecoq, Ayako Wakatsuki Pedersen, Evelina Martinenaite, Shamaila Munir Ahmad, Maria Perez-Penco, Lucia Lara de la Torre, Marion Chapellier, Lars Rønn Olsen, Mia Aaboe-Jørgensen, Hannah Jorinde Glöckner, Anne Mette Askehøj Rømer

“…Tumor-conditioned media (TCM) derived from Arg1-vaccinated mice induced significantly higher upregulation of MHC-II on exposed myeloid cells compared with controls. …”
Get full text

On application of optimal control to SEIR normalized models: Pros and cons by Maria do Rosário de Pinho, Filipa Nunes Nogueira

“…We use optimal control to control by vaccination the spread of a generic infectious disease described by a normalized model with $L^1$ cost. …”
Get full text

Diagnosis and Management of Bacterial Meningitis in the Paediatric Population: A Review by Catherine L. Tacon, Oliver Flower

“…Over recent decades new vaccines have led to a change in epidemiology of the disease; however, it remains a condition that requires a high index of suspicion, prompt diagnosis, and early management in the emergency department. …”
Get full text

New insights into the mechanisms of the immune microenvironment and immunotherapy in osteosarcoma by Cong Luo, Xingxing Min, Danying Zhang

“…It involves recent immunotherapy advances, including monoclonal antibodies, tumor vaccines, immune cell therapies, checkpoint inhibitors, and oncolytic viruses, and discusses combining these with standard treatments.…”
Get full text

South African Rheumatism and Arthritis Association 2024 guidelines for the management of axial spondyloarthritis by A B Maharaj, R Benitha, K Makan, R du Toit, D Haasbroek, C Balton, P Govender, M van Dam, F Paruk, B Hodkinson

“…Screening for comorbidities and vaccination is advised. …”
Get full text

Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

Get full text

Faktor Risiko yang Berhubungan dengan Kejadian Pneumonia pada Balita di Kelurahan Air Tawar Barat Padang by Yulia Efni, Rizanda Machmud, Dian Pertiwi

“…</em><em>5%), exposure to cigarette smoke (</em><em>74.1</em><em>%), a history of low birth weight (</em><em>3.7</em><em>%), did not get measles </em><em>vaccinations</em><em> (40</em><em>.</em><em>7%) and malnutrition (25</em><em>.…”
Get full text

KLRB1 expression in nasopharyngeal mucosa as a prognostic biomarker in COVID-19 patients by Marilina García-Aranda, María Ángeles Onieva, Desirée Martín-García, Raúl Quirós, Inmaculada López, María Padilla-Ruiz, Teresa Téllez, Beatriz Martínez-Gálvez, María Luisa Hortas, Alberto García-Galindo, José González-Gomariz, Rubén Armañanzas, Francisco Rivas-Ruiz, Alfonso Serrano, Isabel Barragán-Mallofret, Maximino Redondo

“…While univariate analysis identified a significant association between KLRB1 expression and vaccination status (p < 0.05), only low KLRB1 expression (OR 1.135, 95% CI: 1.0-1.280), and age (OR 1.033, 95% CI: 1.006–1.061) were confirmed as independent risk factors for ICU admission or death, regardless of other studied variables such as comorbidities, vaccination status, or smoking habits. …”
Get full text