Life Science 2.0: reframing the life science sector for ‘the benefit on mankind’ by Michaela Vallin, Göran Tomson, Beate Kampmann, Eivind Engebretsen, Stefan Swartling Peterson, Rhoda K. Wanyenze, Ole Petter Ottersen

“…The COVID-19 pandemic put the life science sector to the test. Vaccines were developed at unprecedented speed, benefiting from decades of fundamental research and now honoured by a Nobel Prize. …”
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Deep learning-based malaria parasite detection: convolutional neural networks model for accurate species identification of Plasmodium falciparum and Plasmodium vivax by Diego A. Ramos-Briceño, Alessandro Flammia-D’Aleo, Gerardo Fernández-López, Fhabián S. Carrión-Nessi, David A. Forero-Peña

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An evaluation of the severe acute respiratory infection surveillance system in Ireland by Louise Marron, Roisin Duffy, Joan O’Donnell, Lisa Domegan

“…However, improvement in the timeliness of WGS data and recording of vaccination status and equity stratifiers e.g. ethnicity, would strengthen data quality. …”
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Multiple Sclerosis and COVID-19: An Overview on Risk, Severity, and Association With Disease Modifying Therapies by Mary Hollist, Abraham Hollist, Katherine Au, Colton Betts, Maha Kirmani, Maaida Kirmani, Benjamin Armour, Mercy C Udeh, Batool F Kirmani

“…Advancements in management, including vaccinations, antiviral therapy, and targeted prophylaxis, have led to a decline in the incidence and severity of COVID-19. …”
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Analysis and Optimal Control Intervention Strategies of a Waterborne Disease Model: A Realistic Case Study by Obiora Cornelius Collins, Kevin Jan Duffy

“…The model is extended by introducing control intervention strategies such as vaccination, treatment, and water purification. Mathematical analyses of the control model are used to determine the possible benefits of these control intervention strategies. …”
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Best Management Practices for Equines in Natural Disasters by Kelsey M. Irvine, Brandi K. Phillips

“…This publication discusses disaster-specific considerations, making a plan, water and feed, documentation, fence and pasture preparations, animal identification, vaccinations, insurance, what to expect at agricultural inspection station stops, and more. …”
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The Involvement of Microglial Cells in Japanese Encephalitis Infections by Thananya Thongtan, Chutima Thepparit, Duncan R. Smith

“…Despite the availability of effective vaccines, Japanese encephalitis virus (JEV) infections remain a leading cause of encephalitis in many Asian countries. …”
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Dog demography and ecology with reference to rabies in the Amhara region, Ethiopia by Liuel Yizengaw Adnie, Wudu Temesgen Jemberu, Adane Bahiru Woreta, Adugna Berju, Araya Mengistu, Zeleke Tesema Wondie, Wassie Molla, Sefinew Alemu Mekonnen

“…Only 57 % of the dogs were confined, and 16 % of them were vaccinated. Ninety-one percent of the dog owners did not practice neutering and spaying for dog population control. …”
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Effect of nirmatrelvir/ritonavir (Paxlovid) on hospitalization among adults with COVID-19: An electronic health record-based target trial emulation from N3C. by Abhishek Bhatia, Alexander J Preiss, Xuya Xiao, M Daniel Brannock, G Caleb Alexander, Robert F Chew, Hannah Davis, Megan Fitzgerald, Elaine Hill, Elizabeth P Kelly, Hemalkumar B Mehta, Charisse Madlock-Brown, Kenneth J Wilkins, Christopher G Chute, Melissa Haendel, Richard Moffitt, Emily R Pfaff, N3C Consortium

“…We also conducted stratified analyses by vaccination status and age group. Absolute risk reduction for hospitalization was similar among patients that were vaccinated and unvaccinate, but was much greater among patients aged 65+ years than among younger patients. …”
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Immunology and the Central Nervous System by Carlos Barcia, James Curtin, Jeffrey Zirger, Daniel Larocque

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Cohort profile: the potentially preventable burden of community-acquired pneumonia in South African adults in the era of widespread PCV13 immunisation and antiretroviral therapy ro... by Jo Southern, Kennedy Otwombe, Eileen Dunne, Khuthadzo Hlongwane, Bradford D Gessner, Michelle Wong, Cheryl Cohen, Anne von Gottberg, Elizabeth Begier, Sharon Gray, Ebrahim Variava, Tumelo Moloantoa, Neil Martinson, Firdaus Nabeemeeah, Nadia Sabet, Lebohang M Mlambo, Phetho Mangena, Pattamukkil Abraham, Floris Swanepoel, Fahima Moosa, Mark Fletcher, Bha Ndungane-Tlakula, Jerusha Naidoo, Minja Milovanovic

“…Purpose In the setting of an established childhood pneumococcal vaccination programme with immediate initiation and treatment of antiretroviral therapy (ART) for people living with HIV (PLWH), the risk of adult pneumococcal community-acquired pneumonia (CAP) is not recently described. …”
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A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia by Sandra Viz-Lasheras, Alberto Gómez-Carballa, Jacobo Pardo-Seco, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Cristina Calvo, María del Carmen Martínez-Padilla, Ana Pérez-Aragón, Esteban Gómez-Sánchez, Juan Valencia-Ramos, Francisco Giménez-Sánchez, Paula Alonso-Quintela, Laura Moreno-Galarraga, Ulrich von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Clementien L. Vermont, Henriëtte A. Moll, Michael Levin, Federico Martinón-Torres, Antonio Salas

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Kawasaki Disease Complicated by Salmonella oranienburg Coinfection by Zachary Barbara, Savannah P. Ellenwood, Emily D. Loe, Joon Choi, Kathleen Ryan, Nancy Joseph

“…We present a 12-month-old vaccinated male with Kawasaki disease in the setting of Salmonella bacteremia. …”
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The Behavior of an SVIR Epidemic Model with Stochastic Perturbation by Yanan Zhao, Daqing Jiang

“…We discuss a stochastic SIR epidemic model with vaccination. We investigate the asymptotic behavior according to the perturbation and the reproduction number R0. …”
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MEASLES WITH THE COMPLICATION OF NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY; CASE REPORT by Ramna Shafique Rafique, Saleha Haider, Maria Kanwal, Saba Safdar, Tayyaba Anwar, Zain Yousaf Ally

“…It is best prevented through vaccination. Complications that can be seen in measles are otitis media, diarrhea, pneumonia, encephalitis, and myocarditis, and a long-term complication is subacute sclerosing panencephalitis. …”
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New Insights for Immune-Based Diagnosis and Therapy for Infectious Diseases by Giuseppe A. Sautto, Roberta A. Diotti, Karin Wisskirchen, Kristen M. Kahle

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Post-COVID-19 patients’ clinical-epidemiological characteristics in Baracoa, Guantánamo by Yirleidy Rodríguez Labañino, Yodanky Ochoa Rodríguez, Alexander Durán Flores, Denny Matos Laffita, Oneidis Durán Flores

“…COVID-19, in the medium term, had greater implications in the respiratory, nervous and osteomyoarticular systems. Vaccination campaigns help prevent serious symptoms of the virus and counteract complications.…”
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Research Note: Establishment of vector system harboring duck RNA polymerase I promoter for avian influenza virus by Yunyueng Jang, Yoon-Gi Baek, Yu-Na Lee, Ra Mi Cha, Yun-Chan Choi, Min-Ji Park, Youn-Jeong Lee, Eun-Kyoung Lee

“…Reverse genetics (RG) systems are extensively utilized to investigate the characteristics of influenza viruses and develop vaccines, predominantly relying on human RNA polymerase I (pol I). …”
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Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma by Yujiao Zhou, Feifei Liu, Chengmin Li, Guo Shi, Xiaolei Xu, Xue Luo, Yuanling Zhang, Jingjie Fu, Aizhong Zeng, Limin Chen

“…Secondly, bone marrow-derived DCs were infected by Ad-AAH-IRES2-EGFP to yield AAH-DC vaccines. Matured DCs were demonstrated by increased expression of CD11c, CD80, and MHC-II costimulatory molecules. …”
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Salmonella Typhimurium derived OMV nanoparticle displaying mixed heterologous O-antigens confers immunogenicity and protection against STEC infections in mice by Xiaoping Bian, Yaolin Chen, Wenjin Zhang, Xinyu Liu, Meihong Lei, Haoxiang Yuan, Mengru Li, Qing Liu, Qingke Kong

“…Abstract Shiga toxin-producing Escherichia coli (STEC) is one of the major pathogens responsible for severe foodborne infections, and the common serotypes include E. coli O157, O26, O45, O103, O111, O121, and O145. Vaccination has the potential to prevent STEC infections, but no licensed vaccines are available to provide protection against multiple STEC infections. …”
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