Spontaneous high clonal expansion of Wilms’ tumor gene 1-specific cytotoxic T-lymphocytes in patients with Wilms’ tumor gene 1-expressing solid tumor by Soyoko Morimoto, Yukie Tanaka, Jun Nakata, Fumihiro Fujiki, Kana Hasegawa, Hiroko Nakajima, Sumiyuki Nishida, Akihiro Tsuboi, Naoki Hosen, Naoki Kagawa, Motohiko Maruno, Akira Myoui, Takayuki Enomoto, Shuichi Izumoto, Mitsugu Sekimoto, Naoya Hashimoto, Toshiki Yoshimine, Atsushi Kumanogoh, Yusuke Oji, Yoshihiro Oka, Haruo Sugiyama

“…However, the spontaneous WT1-specific immune response before WT1 peptide vaccination in patients with WT1-expressing tumors (PTs) remains unclear. …”
Get full text

Incidence of seroma and postoperative complications after breast surgery before and during the Covid-19 pandemic: results from a retrospective multicenter analysis by Maximilian Heinz Beck, Izabela A. Brachaczek, Pimrapat Gebert, Jens-Uwe Blohmer, Askin C. Kaya, Julia S. M. Zimmermann, Julia C. Radosa, Maria M. Karsten

“…The occurrence of these seromas has been associated with prior SARS-CoV-2 infection or SARS-CoV-2 vaccination. So far, there are few systematic analyses on postoperative complications in breast surgery since the emergence of the SARS-CoV-2 pandemic. …”
Get full text

Community case study: an academia-industry-government partnership that monitors and predicts outbreaks in Tri-County Detroit area since 2017 by Irene Xagoraraki, Liang Zhao, Yabing Li, Brijen Miyani, John Norton, James Broz, Andrew Kaye, Anna Mehrotra, Anil Gosine, Scott Withington, Stacey McFarlane, Russell A. Faust

“…The results of our surveillance efforts are used to assist local health departments in their understanding and response efforts for health issues in the TCDA, facilitating public health messaging for local awareness, targeted clinical testing, and increased vaccination efforts. Our data are available to the local health departments, and our methodological advancements are published and have been used by other communities nationwide and beyond. …”
Get full text

Contributing Factors of Anxiety on Healthcare Workers during COVID-19 Pandemic at Referral Hospital of Sumatra Region in Indonesia by Christine Raphaela Tiarmauli Simanjuntak, Bintang Yinke Magdalena Sinaga, Parluhutan Siagian, Elmeida Effendy, Fotarisman Zaluchu

“…Conclusion:Factors such as gender, marital status, parental status, post-COVID-19 status, family history of COVID-19, vaccination history, and comorbidities did not significantly affect anxiety levels among healthcare workers during the COVID-19 pandemic at Adam Malik General Hospital Medan. …”
Get full text

Behavior changes to promote preconception health: a systematic review by Maiko Suto, Kimiko Inaoka, Daichi Suzuki, Aya Nitamizu, Naoko Arata, Erika Ota

“…Although a consensus exists on the efficacy of folic acid supplementation and preconception vaccination, evidence regarding comprehensive approaches to preconception care targeting the general population remains lacking. …”
Get full text

Computational Study of the Phytochemical Constituents from Uncaria tomentosa Stem Bark against SARS-CoV-2 Omicron Spike Protein by Oscar Herrera-Calderon, Abdulrahman M. Saleh, Andres F. Yepes-Perez, Nada H. Aljarba, Saad Alkahtani, Gaber El-Saber Batiha, Renan Dilton Hañari-Quispe, Haydee Chavez, Josefa Bertha Pari-Olarte, Eddie Loyola-Gonzales, José Santiago Almeida-Galindo, José Francisco Kong-Chirinos, Taoufiq Benali

“…The SARS-CoV-2 Omicron variant has spread rapidly and is considered the predominant variant in the world, and its main characteristic is related to evade immunity from natural infection or vaccines, due to its multiple mutations in the spike protein. …”
Get full text

Baicalein inhibits PRRSV through direct binding, targeting EGFR, and enhancing immune response by Jing Wu, Qi Lu, Jing Hou, Yueqin Qiu, Min Tian, Li Wang, Kaiguo Gao, Xuefen Yang, Zongyong Jiang

“…The current commercial vaccines have limited effectiveness, and there are strict restrictions on the use of antiviral chemical drugs. …”
Get full text

Sexually transmitted diseases and immunology articles pushed by WeChat official accounts are of most interest to the Chinese public: A national cross-sectional study in China by Yi Li, Yinan Zhao, Ning Yao, Shuang Zhou, Beibei Jiang, Ying Xiong, Chunbei Zhou

“…Results: A total of 720 most influential articles from 76 WOAs operated by 69 CDCs were selected for analysis. “Suzhou Vaccination”, “China CDC News” and “Guangdong CDC” were the three top WOAs pushing the most quantities of popular articles. …”
Get full text

Altered Viral Replication and Cell Responses by Inserting MicroRNA Recognition Element into PB1 in Pandemic Influenza A Virus (H1N1) 2009 by Xiaoyue Shen, Wenkui Sun, Yi Shi, Zheng Xing, Xin Su

“…This approach provides an additional layer of biosafety and thus has great potential for the application in the rational development of safer and more effective influenza viral vaccines.…”
Get full text

Evaluation of a pragmatic approach to predicting COVID-19-positive hospital bed occupancy by Azeem Majeed, Thomas Woodcock, Paul Aylin, Julian Redhead, Derryn Lovett, Jacques Naude

“…We extracted data on COVID-19-positive tests, vaccination records and admissions to hospitals with confirmed COVID-19 within the study period. …”
Get full text

Generation of Chicken IgY against SARS-COV-2 Spike Protein and Epitope Mapping by Yan Lu, Yajun Wang, Zhen Zhang, Jingliang Huang, Meicun Yao, Guobin Huang, Yuanyuan Ge, Peichun Zhang, Huaxin Huang, Yong Wang, Huiliang Li, Wen Wang

“…Repurposing approved drugs, developing vaccines and employing passive immunization are three major therapeutic approaches to fighting COVID-19. …”
Get full text

GENOTYPIC DIVERSITY OF DENGUE VIRUS IN AEDES MOSQUITOES COLLECTED FROM DENGUE HOTSPOT AREAS IN KUALA LUMPUR AND SELANGOR, MALAYSIA by Wan Najdah Wan Mohamad Ali, Zurainee Mohamed Nor, Rafidah Ali, Rohani Ahmad, Yvonne Ai-Lian Lim

“…The findings from this study can be utilized to the search for novel genotypes, to the observation of potential genetic alterations in dengue viruses, and to the development of vaccines.…”
Get full text

Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections by Keneth Iceland, Kasozi, Simon Peter, Musinguzi

“…BV activation of the cellular and humoral immune systems should be explored for the application of complementary medicine for the management of SARS-CoV-2 infections. BV “vaccination” is used to immunize against cytomegalovirus and can suppress metastases through the PLA2 and phosphatidylinositol-(3,4)-bisphosphate pathways. …”
Get full text

Separation and purification of chicken IgY with its field efficacy in controlling avian influenza in Muscovy ducks by F. M. Radwan, A. A. El-Shemy, N. I. Toaleb, M. A. Bastamy, M. M. Amer

“…The IgY was prepared using the polymer precipitation method and was found to have high hemagglutination inhibition (HI) mean titres against H5, H9, and ND by the 5th and 8th week post-vaccination (wpv). The separated IgY had mean HI titres against H5 7.20±0.46 and 7.60±0.74 for 5 and 8 wpv, respectively. …”

Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…Without widely available vaccines, mosquito control is the primary tool for fighting the spread of these viruses. …”
Get full text

Molecular Epidemiology of Human Norovirus Variants from Outbreaks in Zhejiang Province, China, during 2021 by Yi Sun, Yongjuan Yuan, Haiyan Mao, Lingxuan Su, Qiong Ge, Jian Gao, Changping Xu, Liming Gong

“…Continued molecular surveillance of noroviruses should be strengthened in our further efforts to the development of vaccines.…”
Get full text

Finanční zajištění židovských uprchlíků v době první světové války v Čechách by Klára Habartová

“…To prevent the spread of infectious diseases, the refugees were vaccinated, given medical checkups and inspected to ensure they were clean. …”
Get full text

Rabies transmitted from vampires to cattle: An overview. by Diego Soler-Tovar, Luis E Escobar

“…., education, early diagnosis, vaccination) have been effective. The increase in the number of outbreaks could suggest that the factors facilitating cross-species transmission could be on the rise.…”
Get full text

Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling by Jennifer S. Ward, Karl J. Schreiber, John Tam, Ji-Young Youn, Roman A. Melnyk

“…Further characterizing the intoxication mechanisms of these proteins is important for the development of vaccines and treatments for toxin-mediated disease. …”
Get full text

IL-18 Blockage Reduces Neuroinflammation and Promotes Functional Recovery in a Mouse Model of Spinal Cord Injury by Easmin Begum, Md Rashel Mahmod, Md Mahbobur Rahman, Fumiko Fukuma, Takeshi Urano, Yuki Fujita

Get full text